Johannes Hofland, Massimo Falconi, Emanuel Christ, Justo P Castaño, Antongiulio Faggiano, Angela Lamarca, Aurel Perren, Simona Petrucci, Vikas Prasad, Philippe Ruszniewski, Christina Thirlwell, Marie-Pierre Vullierme, Staffan Welin, Detlef K Bartsch
This ENETS guidance paper aims to provide practical advice to clinicians for the diagnosis, treatment and follow-up of functioning syndromes in pancreatic neuroendocrine tumours (NET). A NET-associated functioning syndrome is defined by the presence of a clinical syndrome combined with biochemical evidence of inappropriately elevated hormonal levels. Different hormonal syndromes can be encountered in pancreatic NET patients, including insulinoma, gastrinoma as well as the rare glucagonoma, VIPoma, ACTHoma, PTHrPoma, carcinoid syndrome, calcitoninoma, GHRHoma and somatostatinoma...
August 2023: Journal of Neuroendocrinology