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Stenosis spinal canal

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https://www.readbyqxmd.com/read/27889106/expression-of-the-jak-stat-signaling-pathway-in-the-ligamentum-flavum-of-patients-with-lumbar-spinal-canal-stenosis
#1
Hitoshi Yamahata, Koji Osuka, Tatsuro Aoyama, Muneyoshi Yasuda, Hiroshi Tokimura, Kazunori Arita, Masakazu Takayasu
BACKGROUND: Ligamentum flavum (LF) hypertrophy is an important cause of lumbar spinal canal stenosis (LSS), one of the most common spinal disorders in the elderly. Although many cytokines are reported to be associated with LF hypertrophy, the intracellular signaling system is rarely discussed. The purpose of this study was to identify the JAK/STAT signaling pathway and to examine the role of the JAK/STAT systems in the hypertrophied LF. METHODS: The LF of 10 LSS patients was analyzed and the expression of JAK1, STAT3, phosphorylated (p)-STAT3, and actin was examined by Western blot analysis...
November 23, 2016: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
https://www.readbyqxmd.com/read/27828664/surgical-treatment-of-denis-type-b-thoracolumbar-burst-fracture-with-neurological-deficiency-by-paraspinal-approach
#2
H Wu, D-X Zhao, R Jiang, X-Y Zhou
We aimed to describe the surgical technique and clinical outcomes of paraspinal-approach reduction and fixation (PARF) in a group of patients with Denis type B thoracolumbar burst fracture (TLBF) with neurological deficiencies. A total of 62 patients with Denis B TLBF with neurological deficiencies were included in this study between January 2009 and December 2011. Clinical evaluations including the Frankel scale, pain visual analog scale (VAS) and radiological assessment (CT scans for fragment reduction and X-ray for the Cobb angle, adjacent superior and inferior intervertebral disc height, and vertebral canal diameter) were performed preoperatively and at 3 days, 6 months, and 1 and 2 years postoperatively...
2016: Brazilian Journal of Medical and Biological Research, Revista Brasileira de Pesquisas Médicas e Biológicas
https://www.readbyqxmd.com/read/27788683/analysis-of-the-independent-risk-factors-of-neurologic-deficit-after-thoracolumbar-burst-fracture
#3
Peifu Tang, Anhua Long, Tao Shi, Licheng Zhang, Lihai Zhang
BACKGROUND: The objective of this study is to identify the independent risk factors of neurologic deficit after thoracolumbar burst fracture. Traumatic fractures of the thoracolumbar spine are the most common type of spinal column fractures. Many studies have attempted to determine whether neurologic deficit in such fractures is related to spinal canal stenosis or other parameters observed on axial computed tomography. However, this relationship remains controversial. METHODS: A review of the clinical data and axial computed tomography (CT) for 105 patients was performed...
October 24, 2016: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/27775931/sublaminar-decompression-a-new-technique-for-spinal-canal-decompression-in-the-treatment-of-stenosis-in-degenerative-spinal-conditions
#4
Khaled M Kebaish, Benjamin D Elder, Sheng-Fu L Lo, Timothy F Witham
STUDY DESIGN: Technical report and case illustration. OBJECTIVE: To review the rationale and steps for a sublaminar decompression in the setting of adult deformity surgery and in degenerative spondylosis. SUMMARY OF BACKGROUND DATA: Several variations of lumbar laminotomy and posterior decompressions have been reported, although these are primarily in the setting of isolated lumbar stenosis, and often focus on treatment of central stenosis...
October 21, 2016: Clinical Spine Surgery
https://www.readbyqxmd.com/read/27753699/lumbar-spinal-surgery-in-patients-with-parkinson-disease-a-multicenter-retrospective-study
#5
Hiroaki Kimura, Shunsuke Fujibayashi, Bungo Otsuki, Mitsuru Takemoto, Jitsuhiko Shikata, Seiichi Odate, Mutsumi Matsushita, Akira Kusuba, Youngwoo Kim, Takeshi Sakamoto, Kei Watanabe, Masato Ota, Masanori Izeki, Naoya Tsubouchi, Shuichi Matsuda
STUDY DESIGN: A multicenter, retrospective study. OBJECTIVE: To identify the factors that affect surgery-related complications and to clarify the surgical strategy for treating lumbar disorders in Parkinson disease (PD). SUMMARY OF BACKGROUND DATA: Previous studies have reported a high complication rate for spinal surgery in patients with PD. Because of the limited number of studies, there are no guidelines for spinal surgery for PD patients...
October 6, 2016: Clinical Spine Surgery
https://www.readbyqxmd.com/read/27751507/-spinal-extradural-arachnoid-cyst-a-case-report-and-review-of-literature
#6
Javier Quillo-Olvera, Javier Quillo-Reséndiz, Carlos-Francisco Gutiérrez-Partida, Manuel Rodríguez-García
BACKGROUND: Arachnoid cysts of spine are a very rare occurrence. The aetiology still remains unclear, but the most accepted explanation is the existence of areas of weakness in the spinal dura. Symptoms depend on the location in the spine. Magnetic resonance imaging is used for its diagnosis. Management depends of clinical presentation, and the surgery is reserved for patients with neurological impairment. CLINICAL CASE: A case is described of 67 year-old male with myelopathy and radiculopathy symptoms, both diagnosed simultaneously...
October 14, 2016: Cirugia y Cirujanos
https://www.readbyqxmd.com/read/27713009/cervical-spinal-canal-stenosis-first-presenting-after-spinal-cord-injury-due-to-minor-trauma-an-insight-into-the-value-of-preventive-decompression
#7
Hideki Shigematsu, Jason Pui Yin Cheung, Kin-Cheung Mak, Mauro Bruzzone, Keith D K Luk
PURPOSE: Patients with pre-existing cervical spinal canal stenosis (CSCS) may have minimal or no symptoms. However, performing preventive decompression is controversial as the incidence of CSCS leading to severe cord injury is unknown. Hence, this study aims to revisit the threshold for surgery in "silent" CSCS by reviewing the neurologic outcomes of patients with undiagnosed CSCS who sustained a cervical spinal cord injury (CSCI). METHODS: Two groups of subjects were recruited for analysis...
October 3, 2016: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
https://www.readbyqxmd.com/read/27711137/comparison-study-between-conventional-sequence-and-slice-encoding-metal-artifact-correction-semac-in-the-diagnosis-of-postoperative-complications-in-patients-receiving-lumbar-inter-body-fusion-and-pedicle-screw-fixation-surgery
#8
Sol Bee Han, Young Cheol Yoon, Jong Won Kwon
BACKGROUND AND PURPOSE: Slice-Encoding Metal Artifact Correction (SEMAC) sequence is one of the metal artifact reduction techniques of anatomical structure, but there has been no report about evaluation of post-operative complications. The purpose of this article is to compare the anatomical visibility between fast spin echo (FSE) and FSE-SEMAC and to evaluate the additional value of FSE-SEMAC in diagnostic confidence of the complications. MATERIALS AND METHODS: We conducted a retrospective study with 54 patients who received lumbar spinal surgery and MR images including FSE-SEMAC...
2016: PloS One
https://www.readbyqxmd.com/read/27685350/labor-epidural-intolerance-due-to-a-congenitally-narrowed-spinal-canal
#9
David M Dickerson, Ran Dai, Barbara M Scavone, William McDade
Reports exist of severe upper back pain of unknown etiology after administration of large volumes into the epidural space. We present a case of an otherwise healthy parturient who developed severe upper back and neck pain after receiving only a small volume of epidural medication. Magnetic resonance imaging revealed a congenitally narrowed spinal canal because of short pedicle syndrome. Epidural injectate occupies and compresses a percentage of the spinal canal and its neuronal contents. This may result in pain and epidural intolerance when continued injectate reaches a critical point, a threshold that is lower with shortened pedicles or congenital spinal stenosis...
September 28, 2016: Regional Anesthesia and Pain Medicine
https://www.readbyqxmd.com/read/27684879/laminoplasty-with-lateral-mass-screw-fixation-for-cervical-spondylotic-myelopathy-in-patients-with-athetoid-cerebral-palsy-a-retrospective-study
#10
Hua Zhou, Zhong-Jun Liu, Shao-Bo Wang, Sheng-Fa Pan, Ming Yan, Feng-Shan Zhang, Yu Sun
Although several studies report various treatment solutions for cervical spondylotic myelopathy in patients with athetoid cerebral palsy, long-term follow-up studies are very rare. None of the reported treatment solutions represent a gold standard for this disease owing to the small number of cases and lack of long-term follow-up. This study aimed to evaluate the outcomes of laminoplasty with lateral mass screw fixation to treat cervical spondylotic myelopathy in patients with athetoid cerebral palsy from a single center...
September 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27683710/cervical-disc-herniation-as-a-trigger-for-temporary-cervical-cord-ischemia
#11
Güliz Acker, Ulf C Schneider, Zarko Grozdanovic, Peter Vajkoczy, Johannes Woitzik
BACKGROUND: Disc herniations are only reported in few case reports as a rare cause of acute spinal ischemia. A surgical treatment has not been described so far in these reports with analysis of diffusion weighted magnetic resonance imaging (DWI/MRI) before and after surgery. The aim of our study is to report a case of cervical spinal cord ischemia caused by cervical disc herniation and discuss the literature concerning diagnostic and treatment options. METHODS: A 72-year-old female patient developed an acute progressive tetraparesis with emphasis on the upper extremities...
June 2016: Journal of Spine Surgery (Hong Kong)
https://www.readbyqxmd.com/read/27683674/lumbar-interbody-fusion-techniques-indications-and-comparison-of-interbody-fusion-options-including-plif-tlif-mi-tlif-olif-atp-llif-and-alif
#12
REVIEW
Ralph J Mobbs, Kevin Phan, Greg Malham, Kevin Seex, Prashanth J Rao
Degenerative disc and facet joint disease of the lumbar spine is common in the ageing population, and is one of the most frequent causes of disability. Lumbar spondylosis may result in mechanical back pain, radicular and claudicant symptoms, reduced mobility and poor quality of life. Surgical interbody fusion of degenerative levels is an effective treatment option to stabilize the painful motion segment, and may provide indirect decompression of the neural elements, restore lordosis and correct deformity. The surgical options for interbody fusion of the lumbar spine include: posterior lumbar interbody fusion (PLIF), transforaminal lumbar interbody fusion (TLIF), minimally invasive transforaminal lumbar interbody fusion (MI-TLIF), oblique lumbar interbody fusion/anterior to psoas (OLIF/ATP), lateral lumbar interbody fusion (LLIF) and anterior lumbar interbody fusion (ALIF)...
December 2015: Journal of Spine Surgery (Hong Kong)
https://www.readbyqxmd.com/read/27679727/imaging-of-juvenile-idiopathic-arthritis-part-ii-ultrasonography-and-mri
#13
REVIEW
Iwona Sudoł-Szopińska, Elżbieta Grochowska, Piotr Gietka, Mateusz Płaza, Grzegorz Pracoń, Fadhil Saied, Marta Walentowska-Janowicz
Juvenile idiopathic arthritis is the most common autoimmune systemic disease of the connective tissue affecting individuals in the developmental age. Radiography, which was described in the first part of this publication, is the standard modality in the assessment of this condition. Ultrasound and magnetic resonance imaging enable early detection of the disease which affects soft tissues, as well as bones. Ultrasound assessment involves: joint cavities, tendon sheaths and bursae for the presence of synovitis, intraand extraarticular fat tissue to visualize signs of inflammation, hyaline cartilage, cartilaginous epiphysis and subchondral bone to detect cysts and erosions, and ligaments, tendons and their entheses for signs of enthesopathies and tendinopathies...
September 2016: Journal of Ultrasonography
https://www.readbyqxmd.com/read/27676973/sustainable-reduction-in-the-occurrence-of-falls-in-a-parkinson-s-patient-who-followed-an-intensive-and-specific-rehabilitation-program-to-recalibrate-verticality-perception
#14
Laure Mathevon, Nicolas Leroux, Céline Piscicelli, Emmanuelle Clarac, Shenhao Dai, Patrice Davoine, Paul Krack, Dominic Perennou
OBJECTIVE: To take care of postural disorders is a major issue in Parkinson's disease (PD). We present a documented observation suggesting the existence of a biased representation of verticality in PD, resulting in a severe retropulsion and recurrent falls. A rehabilitation program aimed to modulate verticality perception dramatically improved the postural perception of the vertical, trunk posture and balance abilities, and reduced retropulsion as well as lastingly fall frequency. OBSERVATIONS: A 68 year-old patient with Parkinson's disease fall backward 3 times a day...
September 2016: Annals of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/27660596/effect-of-tens-versus-placebo-on-walking-capacity-in-patients-with-lumbar-spinal-stenosis-a-protocol-for-a-randomized-controlled-trial
#15
Carlo Ammendolia, Pierre Côté, Y Raja Rampersaud, Danielle Southerst, Brian Budgell, Claire Bombardier, Gillian Hawker
BACKGROUND: Lumbar spinal stenosis (LSS) is a growing health problem and a leading cause of disability and loss of independence in older adults. It is usually caused by age-related degenerative narrowing of the spinal canals leading to compression and ischemia of the spinal nerves and symptoms of neurogenic claudication. Limited walking ability is the dominant functional impairment caused by LSS. Animal studies suggest increased blood flow to the spinal nerves and spinal cord with superficial paraspinal electrical stimulation...
September 2016: Journal of Chiropractic Medicine
https://www.readbyqxmd.com/read/27651508/eidurographic-findings-following-percutaneous-epidural-adhesiolysis-failed-to-correlate-with-level-of-pain-reduction-in-patients-with-lumbar-spinal-stenosis
#16
Chan Hong Park, Sang Ho Lee
BACKGROUND : Spinal stenosis is characterized by narrowing of the spinal canal, with mechanical compression of spinal nerve roots. The latter may cause low back pain and/or leg pain, as well as neurogenic claudication. Epidural steroid injection is commonly used to treat patients with lumbar spinal stenosis (LSS), but percutaneous epidural adhesiolysis has been utilized when symptoms prove refractory. Our goal was to assess the relationship between improvement shown on epidurogram and subjective patient response to adhesiolysis...
September 20, 2016: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/27648683/decompression-surgery-for-lumbar-spinal-canal-stenosis-in-octogenarians-a-single-center-experience-of-121-consecutive-patients
#17
Alexander Antoniadis, Nils H Ulrich, Samuel Schmid, Mazda Farshad, Kan Min
INTRODUCTION: With increasing age, ubiquitous degeneration processes lead to a narrowing of the spinal canal. Degenerative lumbar spinal stenosis (DLSS) causes functional disability and is associated with back and lower extremity pain in older individuals. The goal of this study was to determine if decompression surgery can be performed safely and provide a stable benefit in our octogenarian patient population. METHODS: In this retrospective study, 121 patients over the age of 80 (mean age: 82...
September 20, 2016: British Journal of Neurosurgery
https://www.readbyqxmd.com/read/27639917/facet-joint-injection-versus-epidural-steroid-injection-for-lumbar-spinal-stenosis-intra-individual-study
#18
E Shim, J W Lee, E Lee, T Im, Y Kang, J M Ahn, H S Kang
AIM: To evaluate the efficacy of facet joint injection (FJI) for patients with lumbar central canal stenosis (LCS) in comparison with epidural steroid injection (ESI) in the same individuals. MATERIAL AND METHODS: Two hundred and fifty-two patients who underwent both FJI and ESI for LCS between January 2014 and December 2014 were considered for enrolment in the study. A radiologist retrospectively conducted a chart review and recorded which injection was chosen as the third injection after sequential injections of FJI and ESI, and why clinicians chose the particular injection method...
October 8, 2016: Clinical Radiology
https://www.readbyqxmd.com/read/27635416/the-paradoxical%C3%A2-relationship-between-ligamentum-flavum-hypertrophy-and-developmental-lumbar-spinal-stenosis
#19
Prudence Wing Hang Cheung, Vivian Tam, Victor Yu Leong Leung, Dino Samartzis, Kenneth Man-Chee Cheung, Keith Dip-Kei Luk, Jason Pui Yin Cheung
BACKGROUND: Ligamentum flavum (LF) hypertrophy is a common cause of lumbar spinal stenosis and is thought to be degeneration-driven. Developmental spinal stenosis (DSS) is characterized by pre-existing narrowed spinal canals and is likely a developmental problem that occurs in childhood. In these cases, the LF may demonstrate different characteristics as compared to degeneration-driven stenosis. Thus, this study aimed to investigate the relationship between histological changes of LF and canal size...
2016: Scoliosis and Spinal Disorders
https://www.readbyqxmd.com/read/27618324/neuroimaging-findings-in-patients-with-mucopolysaccharidosis-what-you-really-need-to-know
#20
Roberta Reichert, Lillian Gonçalves Campos, Filippo Vairo, Carolina Fischinger Moura de Souza, Juliano Adams Pérez, Juliana Ávila Duarte, Fernando Araujo Leiria, Maurício Anés, Leonardo Modesti Vedolin
Mucopolysaccharidosis (MPS) is an inherited metabolic disease and a member of the group of lysosomal storage disorders. Its hallmark is a deficiency of lysosomal enzymes involved in the degradation of mucopolysaccharides, also known as glycosaminoglycans (GAGs). The products of GAG degradation accumulate within lysosomes and in the extracellular space, thereby interfering with the degradation of other macromolecules. This process leads to chronic degeneration of cells, which in turn affects multiple organs and systems...
September 2016: Radiographics: a Review Publication of the Radiological Society of North America, Inc
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