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https://www.readbyqxmd.com/read/29348003/the-waterhub-at-emory-university-campus-resiliency-through-decentralized-reuse
#1
Daniel Allison, Eric Lohan, Tim Baldwin
  In the spring of 2015, Emory University in Atlanta, GA, commissioned an innovative campuswide water reclamation and reuse system known as the WaterHub®. Treating up to 400,000 gallons each day, the system can recycle the equivalent of two-thirds of the University's wastewater production and reduce the campus water footprint by up to 40 percent.One of the first district-scale water reuse systems in North America, the WaterHub mines wastewater from the campus sewer system and repurposes it for beneficial reuse on campus...
February 1, 2018: Water Environment Research: a Research Publication of the Water Environment Federation
https://www.readbyqxmd.com/read/29343675/diagnostic-accuracy-of-quantitative-flow-ratio-for-assessing-myocardial-ischemia-in-prior-myocardial-infarction
#2
Hiroki Emori, Takashi Kubo, Takeyoshi Kameyama, Yasushi Ino, Yoshiki Matsuo, Hironori Kitabata, Kosei Terada, Yosuke Katayama, Hiroshi Aoki, Akira Taruya, Kunihiro Shimamura, Shingo Ota, Atsushi Tanaka, Takeshi Hozumi, Takashi Akasaka
BACKGROUND: A novel index of the functional severity of coronary stenosis, quantitative flow ratio (QFR), may not consider the amount of viable myocardium in prior myocardial infarction (MI) because QFR is calculated from 3D quantitative coronary angiography.Methods and Results:We analyzed QFR (fixed-flow QFR [fQFR] and contrast-flow QFR [cQFR]) and fractional flow reserve (FFR) in prior-MI-related coronary arteries (n=75) and non-prior-MI-related coronary arteries (n=75). Both fQFR and cQFR directly correlated with FFR in the prior-MI-related coronary arteries (fQFR: r=0...
January 16, 2018: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/29324393/changing-students-perceptions-of-the-homeless-a-community-service-learning-experience
#3
Janet Gardner, Jan Emory
The homeless are an underserved, local vulnerable population that can benefit from a service learning clinical practicum experience for baccalaureate prepared nursing students. Negative attitudes and disrespect among healthcare workers has been identified by the homeless as a barrier to healthcare. A service learning experience with a vulnerable population has been shown to change nursing students' attitudes and beliefs. A large university in a southern city partnered with a community based organization that provided services to the homeless to educate senior nursing students in a service learning experience...
January 5, 2018: Nurse Education in Practice
https://www.readbyqxmd.com/read/29319132/evaluation-of-changes-in-perfusion-defect-and-left-ventricular-systolic-function-using-tc-99m-tetrofosmin-single-photon-emission-computed-tomography-over-3-month-period-in-patients-of-acute-myocardial-infarction-undergoing-primary-angioplasty
#4
Anil Kumar Avs, P G Kumar, Ajay Swami, Yiteedra Dinker
BACKGROUND: After a primary transluminal coronary angioplasty (PTCA) following AMI (acute myocardial infarction), the perfusion defect and LV (left ventricular) function recover/change over a period of time. The analysis immediately after the procedure may not be true depiction of the exact success of the procedure. There is varying and scanty information available on the natural course of changes in these parameters after a successful PTCA. We hypothesized that majority of change occurs at 3-4 month period...
January 10, 2018: Nuclear Medicine Review. Central & Eastern Europe
https://www.readbyqxmd.com/read/29316590/hemiarthroplasty-for-fractures-of-metastatic-bone-disease-have-different-outcomes-compared-to-fractures-without-metastasis-a-matched-pair-analysis
#5
Samuel Rosas, Alejandro Marquez-Lara, Alexander H Jinnah, Martin W Roche, Jeffrey S Willey, Chukwuweike Gwam, Cynthia L Emory
INTRODUCTION: Hemiarthropalsty (HA) for proximal femur fractures (PFF) has shown good results in the elderly patient population. It has also been used to treat fractures of the proximal femur in patients with metastatic bone disease (MBD). Nonetheless, complications still occur in both patient populations and their effect on 90-day costs can be a great burden to the healthcare system. Thus, the purpose of this study was to evaluate and compare the outcomes and costs of HA for PFF in patients with bone metastasis versus those without it...
December 22, 2017: Surgical Technology International
https://www.readbyqxmd.com/read/29313398/a-15-year-review-of-secondary-and-tertiary-optic-nerve-sheath-fenestration-for-idiopathic-intracranial-hypertension
#6
Andrew J Anzeljc, Patrick Frias, Brent R Hayek, Nancy Canter Weiner, Ted H Wojno, H Joon Kim
PURPOSE: Optic nerve sheath fenestration (ONSF) is a common surgical option for patients with idiopathic intracranial hypertension (IIH) with vision loss refractory to medical management. Little is known about the visual benefit of repeated ONSF. The authors aimed to assess the efficacy of secondary and tertiary ONSF in patients with IIH. METHODS: A retrospective chart review was performed on all patients with repeat ONSF for IIH at Emory University from 1999 to 2016...
January 9, 2018: Orbit
https://www.readbyqxmd.com/read/29306690/differential-change-on-depressive-symptom-factors-with-antidepressant-medication-and-cognitive-behavior-therapy-for-major-depressive-disorder
#7
Boadie W Dunlop, Steven P Cole, Charles B Nemeroff, Helen S Mayberg, W Edward Craighead
BACKGROUND: Major depressive disorder (MDD) is a heterogeneous condition and individual patients are likely to be differentially responsive to specific treatments. In an exploratory factor analysis of three rating scales, the Genome-based Therapeutic Drugs for Depression (GENDEP) trial identified three factors that were differentially associated with outcome to nortriptyline and escitalopram. However, this factor analysis has neither been replicated or applied to a psychotherapy treatment...
December 27, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29303890/comparative-outcomes-and-toxicities-for-ruthenium-106-versus-palladium-103-in-the-treatment-of-choroidal-melanoma
#8
Hasan Danish, Matthew J Ferris, Ehsan Balagamwala, Jeffrey M Switchenko, Kirtesh R Patel, Maria Choudhary, Caroline Craven, Pia Mendoza, John Suh, Chris Bergstrom, Hans E Grossniklaus, Thomas M Aaberg, Arun Singh, Ian R Crocker, Mohammad K Khan
For the treatment of choroidal melanoma, palladium-103 (Pd) and ruthenium-106 (Ru) plaque brachytherapy shows reduced toxicity compared with the historical standard iodine-125. No report has directly compared the clinical outcomes between Pd and Ru, and the reasons for the selection of one over the other remain purely theoretical. Patients with choroidal melanoma with apical tumor height up to 5 mm were included. Patients from Emory University were treated with Pd between 1993 and 2012. Patients from Cleveland Clinic were treated with Ru between 2005 and 2010...
January 3, 2018: Melanoma Research
https://www.readbyqxmd.com/read/29289917/the-number-of-prior-lines-of-systemic-therapy-as-a-prognostic-factor-for-patients-with-brain-metastases-treated-with-stereotactic-radiosurgery-results-of-a-large-single-institution-retrospective-analysis
#9
Claire M Lanier, Emory McTyre, Michael LeCompte, Christina K Cramer, Ryan Hughes, Kounosuke Watabe, Hui-Wen Lo, Stacey O'Neill, Michael T Munley, Adrian W Laxton, Stephen B Tatter, Jimmy Ruiz, Michael D Chan
OBJECTIVES: It is presently unknown whether patients with brain metastases from heavily pre-treated cancers have a significantly different prognosis than those with less pre-treatment. In this study we sought to identify whether the number of prior lines of systemic therapy are associated with clinical outcomes in patients with brain metastases who received stereotactic radiosurgery (SRS). PATIENTS AND METHODS: Between July 2000 and July 2017, 377 patients with brain metastases were treated with upfront SRS...
December 27, 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/29289540/a-randomized-controlled-study-comparing-a-dpp4-inhibitor-linagliptin-and-basal-insulin-glargine-in-patients-with-type-2-diabetes-in-long-term-care-and-skilled-nursing-facilities-linagliptin-ltc-trial
#10
Guillermo E Umpierrez, Saumeth Cardona, David Chachkhiani, Maya Fayfman, Sahebi Saiyed, Heqiong Wang, Priyathama Vellanki, J Sonya Haw, Darin E Olson, Francisco J Pasquel, Theodore M Johnson
OBJECTIVES: Safe and easily implemented treatment regimens are needed for the management of patients with type 2 diabetes mellitus (T2DM) in long-term care (LTC) and skilled nursing facilities. DESIGN: This 6-month open-label randomized controlled trial compared the efficacy and safety of a DPP4 inhibitor (linagliptin) and basal insulin (glargine) in LTC residents with T2DM. SETTINGS: Three LTC institutions affiliated with a community safety-net hospital, US Department of Veterans Affairs and Emory Healthcare System in Atlanta, Georgia...
December 27, 2017: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/29288185/cohort-profile-the-emory-cardiovascular-biobank-emcab
#11
Yi-An Ko, Salim Hayek, Pratik Sandesara, Ayman Samman Tahhan, Arshed Quyyumi
PURPOSE: The Emory Cardiovascular Biobank (EmCAB) is an ongoing prospective registry of patients undergoing cardiac catheterisation, which was established to identify novel factors associated with the pathobiological process and treatment of cardiovascular disease. PARTICIPANTS: Individuals aged 18 years and older undergoing cardiac catheterisation at three Emory Healthcare sites in Atlanta are asked to participate in this prospective registry. Around 95% agree to participate...
December 29, 2017: BMJ Open
https://www.readbyqxmd.com/read/29286945/an-interpretable-machine-learning-model-for-accurate-prediction-of-sepsis-in-the-icu
#12
Shamim Nemati, Andre Holder, Fereshteh Razmi, Matthew D Stanley, Gari D Clifford, Timothy G Buchman
OBJECTIVES: Sepsis is among the leading causes of morbidity, mortality, and cost overruns in critically ill patients. Early intervention with antibiotics improves survival in septic patients. However, no clinically validated system exists for real-time prediction of sepsis onset. We aimed to develop and validate an Artificial Intelligence Sepsis Expert algorithm for early prediction of sepsis. DESIGN: Observational cohort study. SETTING: Academic medical center from January 2013 to December 2015...
December 26, 2017: Critical Care Medicine
https://www.readbyqxmd.com/read/29276556/atrial-fibrillation-predictors-on-mobile-cardiac-telemetry-in-cryptogenic-ischemic-stroke
#13
Omar Kass-Hout, Tareq Kass-Hout, Ankit Parikh, Michael Hoskins, Stephen D Clements, Srikant Rangaraju, Ali Reza Noorian, Lauren Ayala, Debra Blanke, Laura Bamford, Aaron Anderson, Samir Belagaje, Manuel Yepes, Michael Frankel, Fadi Nahab
Background and Purpose: The objective of our study was to evaluate magnetic resonance imaging (MRI) and echocardiographic characteristics that would identify patients with cryptogenic ischemic stroke (IS) and transient ischemic attack (TIA) who subsequently developed paroxysmal atrial fibrillation (PAF) on mobile cardiac outpatient telemetry (MCOT). Methods: All patients with cryptogenic IS or TIA seen at the Emory University Hospital and Emory University Hospital Midtown from January 1, 2009, to June 30, 2013, who underwent MCOT were included in this analysis...
January 2018: Neurohospitalist
https://www.readbyqxmd.com/read/29218431/external-validity-of-two-nomograms-for-predicting-distant-brain-failure-after-radiosurgery-for-brain-metastases-in-a-bi-institutional-independent-patient-cohort
#14
Roshan S Prabhu, Robert H Press, Danielle M Boselli, Katherine R Miller, Scott P Lankford, Robert J McCammon, Benjamin J Moeller, John H Heinzerling, Carolina E Fasola, Kirtesh R Patel, Anthony L Asher, Ashley L Sumrall, Walter J Curran, Hui-Kuo G Shu, Stuart H Burri
Patients treated with stereotactic radiosurgery (SRS) for brain metastases (BM) are at increased risk of distant brain failure (DBF). Two nomograms have been recently published to predict individualized risk of DBF after SRS. The goal of this study was to assess the external validity of these nomograms in an independent patient cohort. The records of consecutive patients with BM treated with SRS at Levine Cancer Institute and Emory University between 2005 and 2013 were reviewed. Three validation cohorts were generated based on the specific nomogram or recursive partitioning analysis (RPA) entry criteria: Wake Forest nomogram (n = 281), Canadian nomogram (n = 282), and Canadian RPA (n = 303) validation cohorts...
December 7, 2017: Journal of Neuro-oncology
https://www.readbyqxmd.com/read/29204530/hippocampal-dose-volume-histogram-predicts-hopkins-verbal-learning-test-scores-after-brain-irradiation
#15
Catherine Okoukoni, Emory R McTyre, Diandra N Ayala Peacock, Ann M Peiffer, Roy Strowd, Christina Cramer, William H Hinson, Steve Rapp, Linda Metheny-Barlow, Edward G Shaw, Michael D Chan
Purpose: Radiation-induced cognitive decline is relatively common after treatment for primary and metastatic brain tumors; however, identifying dosimetric parameters that are predictive of radiation-induced cognitive decline is difficult due to the heterogeneity of patient characteristics. The memory function is especially susceptible to radiation effects after treatment. The objective of this study is to correlate volumetric radiation doses received by critical neuroanatomic structures to post-radiation therapy (RT) memory impairment...
October 2017: Advances in Radiation Oncology
https://www.readbyqxmd.com/read/29198929/racial-differences-in-the-development-of-de-novo-donor-specific-antibodies-and-treated-antibody-mediated-rejection-after-heart-transplantation
#16
Robert Townsend Cole, Jonathan Gandhi, Robert A Bray, Howard M Gebel, Michael Yin, Nikolaz Shekiladze, An Young, Aubrey Grant, Ian Mahoney, S Raja Laskar, Divya Gupta, Kunal Bhatt, Wendy Book, Andrew Smith, Duc Nguyen, J David Vega, Alanna A Morris
BACKGROUND: Despite improvements in outcomes after heart transplantation, black recipients have worse survival compared with non-black recipients. The source of such disparate outcomes remains largely unknown. We hypothesize that a propensity to generate de-novo donor-specific antibodies (dnDSA) and subsequent antibody-mediated rejection (AMR) may account for racial differences in sub-optimal outcomes after heart transplant. In this study we aimed to determine the role of dnDSA and AMR in racial disparities in post-transplant outcomes...
November 4, 2017: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/29186335/the-oncoppi-portal-an-integrative-resource-to-explore-and-prioritize-protein-protein-interactions-for-cancer-target-discovery
#17
Andrei A Ivanov, Brian Revennaugh, Lauren Rusnak, Valentina Gonzalez-Pecchi, Xiulei Mo, Margaret A Johns, Yuhong Du, Lee A D Cooper, Carlos S Moreno, Fadlo R Khuri, Haian Fu
Motivation: As cancer genomics initiatives move toward comprehensive identification of genetic alterations in cancer, attention is now turning to understanding how interactions among these genes lead to the acquisition of tumor hallmarks. Emerging pharmacological and clinical data suggest a highly promising role of cancer-specific protein-protein interactions (PPIs) as druggable cancer targets. However, large-scale experimental identification of cancer-related PPIs remains challenging, and currently available resources to explore oncogenic PPI networks are limited...
November 24, 2017: Bioinformatics
https://www.readbyqxmd.com/read/29186324/robust-inference-of-population-structure-from-next-generation-sequencing-data-with-systematic-differences-in-sequencing
#18
Peizhou Liao, Glen A Satten, Yi-Juan Hu
Motivation: Inferring population structure is important for both population genetics and genetic epidemiology. Principal components analysis (PCA) has been effective in ascertaining population structure with array genotype data but can be difficult to use with sequencing data, especially when low depth leads to uncertainty in called genotypes. Because PCA is sensitive to differences in variability, PCA using sequencing data can result in components that correspond to differences in sequencing quality (read depth and error rate), rather than differences in population structure...
November 27, 2017: Bioinformatics
https://www.readbyqxmd.com/read/29179694/correction-to-protocol-for-the-emory-university-african-american-vaginal-oral-and-gut-microbiome-in-pregnancy-cohort-study
#19
Elizabeth J Corwin, Carol J Hogue, Bradley Pearce, Cherie C Hill, Timothy D Read, Jennifer Mulle, Anne L Dunlop
Following publication of the original article [1], the authors pointed out that the Methods included one step that is no longer necessary but which was inadvertently carried over from an earlier protocol.
November 27, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29160015/response-to-in-reply-to-mast-cell-disorders-in-ehlers-danlos-syndrome-jaime-vengoechea-department-of-human-genetics-emory-university
#20
Suranjith L Seneviratne, Anne Maitland, Lawrence B Afrin
No abstract text is available yet for this article.
November 21, 2017: American Journal of Medical Genetics. Part A
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