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Penis cancer

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https://www.readbyqxmd.com/read/29785317/a-rare-case-of-penile-metastases-as-a-harbinger-of-primary-pulmonary-adenosquamous-carcinoma
#1
Partha Hota, Tejas N Patel, Xiaofeng Zhao, Carrie Schneider, Omar Agosto
Although lung cancer has a high propensity for distant metastatic disease, penile metastases from primary lung neoplasms are considered particularly rare. A 71-year-old male presented to our hospital with a rapidly enlarging hard palpable penile mass. MR imaging demonstrated two penile masses centered in the left and right corpus cavernosa. Subsequent CT imaging revealed a spiculated pulmonary mass in the right upper lobe with PET/CT, MRI, and surgical exploration, demonstrating evidence of metastases to the left adrenal gland, right subscapularis muscle, brain, and small bowel...
2018: Case Reports in Radiology
https://www.readbyqxmd.com/read/29782301/lymphangioma-circumscriptum-post-radiotherapy-for-penile-cancer-treated-with-co%C3%A2-laser
#2
Dietmar Schulz, Andreas Lein, Ancuta Proca Nicula, Katrin Schierle, Caius Solovan
Lymphangioma circumscriptum (LC) is a rare, benign condition, predominantly characterized by the malformation of lymphatic skin vessels. Its onset may be congenital or due to secondary causes such as radiotherapy, infections, or surgical procedures. We present the case of a 55-year-old patient with a pathologic history of squamous cell carcinoma of the penis followed by radical penectomy. Due to metastasis to the locoregional lymph nodes, the entire affected area was subsequently treated with radiation therapy, receiving a total dose of 55...
April 2018: Acta Dermatovenerologica Croatica: ADC
https://www.readbyqxmd.com/read/29743937/epidemiologic-and-economic-burden-of-hpv-diseases-in-spain-implication-of-additional-5-types-from-the-9-valent-vaccine
#3
Noelia López, Aureli Torné, Agustín Franco, María San-Martin, Elisabet Viayna, Carmen Barrull, Nuria Perulero
Background: A new nonavalent human papillomavirus (HPV) vaccine that includes genotypes 6/11/16/18/31/33/45/52/58 has been recently approved in Spain. A previous study has shown that attributable fraction of HPV related diseases in Spain is consistent with that reported in European and global studies. The aim of the present study was to estimate the annual direct costs associated to the following HPV-related diseases: genital warts, high grade precancerous lesions and cancer of cervix, vulva, vagina, anus and penis and head and neck cancer, caused by genotypes included in the nonavalent (9vHPV) and quadrivalent vaccines (4vHPV), in Spanish men and women...
2018: Infectious Agents and Cancer
https://www.readbyqxmd.com/read/29719080/lymphovenous-anastomosis-and-debulking-procedure-for-treatment-of-combined-severe-lower-extremity-and-genital-lymphedema-a-case-report
#4
Mario F Scaglioni, Semra Uyulmaz
Lymphedema most commonly occurs after cancer treatment and can affect limbs and genitalia. Genital lymphedema (GL) is a rare condition and can be disabling psychologically and physically. It often occurs along with lower extremity lymphedema (LEL). Conservative and physiologic reconstructive surgery such as lymphaticovenous anastomosis (LVA) offer good treatment options for LEL. GL however remains a reconstructive dilemma. The most effective surgical therapies in advanced GL are still debulking procedures in properly selected patients...
May 2, 2018: Microsurgery
https://www.readbyqxmd.com/read/29684955/-a-case-of-sarcomatoid-squamous-cell-carcinoma-of-the-penis
#5
Atsushi Wanifuchi, Takashi Shimizu, Hiroshi Hotta
A 74-year-old man presented to our hospital with the swelling of penis in May 2016. Physical examination revealed a goose egg-sized lump at the tip of the penis under foreskin. After dorsal skin incision we confirmed the 7 cm tumor on the inner preputial skin and then resected the tumor with circumcision. Histopathological examination revealed sarcomatoid squamous cell carcinoma of the penis. Computed tomography (CT) revealed swelling of bilateral inguinal lymph nodes, and we performed partial penectomy with bilateral superficial inguinal lymph node dissection in July 2016...
February 2018: Hinyokika Kiyo. Acta Urologica Japonica
https://www.readbyqxmd.com/read/29663358/a-case-control-study-of-hiv-infection-and-cancer-in-the-era-of-antiretroviral-therapy-in-rwanda
#6
Tharcisse Mpunga, Ariana Znaor, F Regis Uwizeye, Aline Uwase, Cyprien Munyanshongore, Silvia Franceschi, Gary M Clifford
The aim of our study was to assess the association between HIV infection and cancer risk in Rwanda approximately a decade after the introduction of antiretroviral therapy (cART). All persons seeking cancer care at Butaro Cancer Center of Excellence (BCCOE) in Rwanda from 2012 to 2016 were routinely screened for HIV, prior to being confirmed with or without cancer (cases and controls, respectively). Cases were coded according to ICD-O-3 and converted to ICD10. Associations between individual cancer types and HIV were estimated using adjusted unconditional logistic regression...
April 16, 2018: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/29625136/surgical-management-of-adult-acquired-buried-penis-impact-on-urinary-and-sexual-quality-of-life-outcomes
#7
Katherine M Theisen, Thomas W Fuller, Paul Rusilko
OBJECTIVES: To assess postoperative patient-reported quality of life outcomes following surgical management of adult acquired buried penis (AABP). We hypothesize that surgical treatment of AABP results in improvements in urinary and sexual quality of life. METHODS: Patients that underwent surgical treatment of AABP were retrospectively identified. The Expanded Prostate Cancer Index (EPIC) questionnaire was completed at ≥ 3 months postoperatively, and completed retrospectively to define preoperative symptoms...
April 3, 2018: Urology
https://www.readbyqxmd.com/read/29609831/birth-defects-in-children-of-men-exposed-in-utero-to-diethylstilbestrol-des
#8
Michel Tournaire, Emmanuel Devouche, Sylvie Epelboin, Anne Cabau, Annabel Dunbavand, Anne Levadou
OBJECTIVE: Prenatal exposure to diethylstilbestrol (DES) is associated with adverse effects, including genital anomalies and cancers in men and women. Animal studies showed birth defects and tumors in the offspring of mice prenatally exposed to DES. In humans, birth defects, such as hypospadias were observed in children of prenatally exposed women. The aim of this research was to assess the birth defects in children of prenatally exposed men. METHODS: In a retrospective study conceived by a patients' association (Réseau DES France), the reports of men prenatally exposed to DES on adverse health effects in their children were compared with those of unexposed controls and general population...
March 3, 2018: Thérapie
https://www.readbyqxmd.com/read/29589134/the-relationship-between-hpv-status-and-chemoradiotherapy-in-the-locoregional-control-of-penile-cancer
#9
Zhigang Yuan, Arash O Naghavi, Dominic Tang, Youngchul Kim, Kamran A Ahmed, Jasreman Dhillon, Anna R Giuliano, Philippe E Spiess, Peter A Johnstone
BACKGROUND: Penile cancer (PeCa) is a rare, aggressive malignancy often associated with the human papillomavirus (HPV). The practice of a personalized risk-adapted approach is not yet established. This study is to assess the relationship between HPV tumor status and chemoradiotherapy (CRT) in PeCa locoregional control (LRC). METHODS: We retrospectively identified patients with HPV status who were diagnosed with squamous cell carcinoma of the penis and treated with surgical resection between 1999 and 2016...
March 27, 2018: World Journal of Urology
https://www.readbyqxmd.com/read/29581680/sexuality-in-surgically-treated-carcinoma-penis-patients-and-their-partners
#10
Gajanan S Bhat, Girish Nelivigi, Vijayakumar Barude, Anuradha Shastry
Most common treatment offered to carcinoma penis patients is surgery. This results in not only mutilation of the genitals but also affects their sexuality. The treating physician fails to address the issue due to the paucity of the data in this regard. Hence, we decided to evaluate sexuality in these patients after surgical treatment for penile cancer. Most of the times, their partners also face problems of sex and sexuality, regarding which there is no literature. Hence, we decided to include their partners also in the study...
February 2018: Indian Journal of Surgery
https://www.readbyqxmd.com/read/29509578/penile-metastases-from-renal-cell-carcinoma-pre-and-postcontrast-sonographic-findings
#11
Salvatore Gitto, Marta Vaiani, Tommaso Cascella, Rodolfo Lanocita
The prostate and bladder are the most common primary cancer sites for penile metastases. Here, we describe an unusual case of metastases from renal cell carcinoma to the penis discovered 1 month after nephrectomy in a 60-year-old man. The diagnosis was achieved using B-mode and contrast-enhanced ultrasound.
March 5, 2018: Ultrasound Quarterly
https://www.readbyqxmd.com/read/29494739/treatment-trends-and-outcomes-for-patients-with-lymph-node-positive-cancer-of-the-penis
#12
Shreyas S Joshi, Elizabeth Handorf, David Strauss, Andres F Correa, Alexander Kutikov, David Y T Chen, Rosalia Viterbo, Richard E Greenberg, Robert G Uzzo, Marc C Smaldone, Daniel M Geynisman
Importance: Penile cancer is an uncommon disease with minimal level I evidence to guide therapy. The National Comprehensive Cancer Network (NCCN) guidelines advocate a lymph node dissection (LND) or radiotherapy with consideration of perioperative chemotherapy for all patients with lymph node-positive (LN+) penile cancer without metastasis. Objectives: To determine temporal trends in use of chemotherapy for patients with LN+ penile cancer without metastasis and to evaluate outcomes between those who did or did not receive LND, chemotherapy, and radiotherapy...
March 1, 2018: JAMA Oncology
https://www.readbyqxmd.com/read/29484058/a-report-of-two-deep-seated-noncutaneous-penile-tumors-more-than-meets-the-eye
#13
Kerry Thomas, Philippe Spiess, Jamie T Caracciolo
Penile cancer is an uncommon primary genitourinary malignancy, the vast majority representing superficial squamous cell carcinomas. However, less common skin cancers, secondary malignancies, mesenchymal neoplasms, and hematopoietic tumors do affect the penis. Medical history, atypical presentation, and deep epicenter of a penile mass may raise question of a nonepithelial neoplasm. We describe and discuss 2 examples of rare deep-seated penile malignancies, leiomyosarcoma and B-cell lymphoma.
December 2017: Radiology Case Reports
https://www.readbyqxmd.com/read/29484001/para-and-intraurethral-penile-tumor-like-condilomatosis
#14
Anastasiya Atanasova Chokoeva, Uwe Wollina, Torello Lotti, Georgi Konstantinov Maximov, Ilia Lozev, Georgi Tchernev
Condyloma acuminata represents an epidermal manifestation, associated with the epidermotropic human papillomavirus (HPV). They have been reported as the most common sexually transmitted disease, with prevalence exceeding 50%, increased up to 4 times, within the last two decades, as the most common side of affection are the penis, vulva, vagina, cervix, perineum, and perianal area, with increased prevalence in young, sexually active individuals. Increased attention should be focused on lesions, caused by types, with moderate (33, 35, 39, 40, 43, 45, 51-56, 58) or high risk potential (types 16, 18) for malignant transformation, leading to further development of cancers of anus, vagina, vulva and penis, as well as cancers of the head and neck...
January 25, 2018: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29483984/simultaneous-occurrence-of-balanoposthitis-circumscripta-plasmacellularis-zoon-phimosis-and-in-situ-carcinoma-of-the-penis-case-report-with-an-unusual-ulcerated-polypoid-variant-of-zoon-s-disease-and-a-carcinoma-in-situ-of-reserve-cell-type
#15
Uwe Wollina, Jacqueline Schönlebe, Alberto Goldman, Georgi Tchernev, Torello Lotti
BACKGROUND: Zoon's balanitis is a benign disease characterized by an asymptomatic, chronic, solitary, shiny, red-orange plaque of the glans and/ or prepuce. In rare cases of Zoon's disease, penile squamous cell carcinoma developed in the chronic inflammatory lesions. CASE REPORT: We report on a 68-year-old male patient presenting with phimosis and coexistent Zoon's disease and penile carcinoma in situ treated successfully by circumcision. CONCLUSION: Coexistence of both lesions in contrast to the development of cancerous lesions within pre-existent Zoon's disease is a very rare observation...
January 25, 2018: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29476028/long-term-incidence-trends-of-hpv-related-cancers-and-cases-preventable-by-hpv-vaccination-a-registry-based-study-in-norway
#16
Bo T Hansen, Suzanne Campbell, Mari Nygård
OBJECTIVES: Examine long-term incidence trends of human papillomavirus (HPV)-related cancer in Norway, and estimate the number of cancer cases preventable by vaccines against HPV 16/18 or HPV 16/18/31/33/45/52/58. DESIGN: Observational registry-based study. We extracted incident cases of HPV-related cancer during 1953-2015 from the Cancer Registry of Norway. Tumour HPV prevalence estimates from large international meta-analyses or from Norway were used to estimate the protective potential of HPV vaccines...
February 23, 2018: BMJ Open
https://www.readbyqxmd.com/read/29470654/-molecular-characterization-of-penile-cancer-literature-review-of-new-prognostic-markers-and-potential-therapeutic-targets
#17
REVIEW
M May, S D Brookman-May, T H Ecke, M Burger
Squamous cell carcinoma of the penis (SCCP) is a rare cancer type in Western industrialized nations; nevertheless, it shows an aggressive course of disease in advanced tumor stages with accordantly high recurrence and progression rates. While molecular biomarkers are not established in clinical routine for the management of SCCP patients yet, the accordant unmet need is enormous, as adequate biomarkers would be meaningful for prognostic determination, planning of modality and extent of primary therapy, indication for inguinal lymph node resection, adjuvant treatment, and as potential targets for specific systemic treatment...
April 2018: Der Urologe. Ausg. A
https://www.readbyqxmd.com/read/29468280/-pathology-and-histopathological-evaluation-of-penile-cancer
#18
REVIEW
A Erbersdobler
BACKGROUND: Penile cancer is rare in Germany and in western European countries. Our understanding of the pathogenesis and pathology of this malignancy has increased considerably in recent years. OBJECTIVES: Clinical management has become more complex, with organ-preserving strategies being increasingly favored. Associated with these developments, the demands on the pathology reports of biopsies and surgical specimens from the penis have also increased. MATERIALS AND METHODS: According to guidelines and the relevant literature, this review outlines the most important aspects that must be considered in the classification and pathological reporting of penile cancer...
April 2018: Der Urologe. Ausg. A
https://www.readbyqxmd.com/read/29468279/-epidemiology-of-penile-cancer
#19
REVIEW
C Colberg, C van der Horst, K-P Jünemann, C M Naumann
BACKGROUND: Penile cancer represents a rarity in daily clinical practice. OBJECTIVES: The aim is to identify global differences concerning the incidence, social and risk factors. METHODS: The past and current epidemiologic literature is analyzed concerning incidence rates and risk factors. The latter are discussed concerning their potential with regard to disease prevention. RESULTS: Globally, incidence rates of penile cancer range from low to nonexistent...
April 2018: Der Urologe. Ausg. A
https://www.readbyqxmd.com/read/29465493/unusual-case-of-diffuse-penile-metastasis-of-prostate-cancer-on-68ga-psma-pet-ct-imaging-and-177lu-psma-posttherapy-scintigraphy
#20
Shelvin Kumar Vadi, Rajender Kumar, Bhagwant Rai Mittal, Ashwin Singh Parihar, Shrawan Kumar Singh
An 85-year-old man with prostate cancer for metastatic workup underwent Gallium Prostate-Specific Membrane Antigen (Ga-PSMA) PET/CT (Ga-PSMA PET/CT), which revealed unusual tracer uptake in the shaft and glans of penis as well as multiple systemic metastases in liver, skeletal, and lymph nodes. The penile lesion was proved to be metastatic adenocarcinoma from prostate on fine needle aspiration cytology. The patient underwent Lutetium (Lu)-labeled PSMA radioligand therapy, which also revealed diffuse tracer uptake in the penile shaft as well as other metastatic sites...
April 2018: Clinical Nuclear Medicine
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