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https://www.readbyqxmd.com/read/29678456/inflatable-penile-prosthesis-placement-scratch-technique-and-postoperative-vacuum-therapy-as-a-combined-approach-in-the-definitive-treatment-of-patients-with-peyronie-s-disease
#1
G Antonini, E De Berardinis, F Del Giudice, G M Busetto, S Lauretti, R Fragas, B I Chung, S L Conti, D Giannarelli, I Sperduti, M S Gross, P E Perito
PURPOSE: Peyronie's disease (PD) is a devastating condition resulting in penile deformity, erectile dysfunction (ED), pain and emotional distress. This prospective two institution study evaluates a multimodal surgical and mechanical combined approach in the definitive treatment of PD and concomitant ED. MATERIALS AND METHODS: 145 selected patients underwent endocavernosal disruption of the PD plaques via the "scratch technique" followed by inflatable penile prosthesis (IPP) insertion...
April 17, 2018: Journal of Urology
https://www.readbyqxmd.com/read/29675596/post-finasteride-syndrome-and-post-ssri-sexual-dysfunction-two-sides-of-the-same-coin
#2
REVIEW
Silvia Giatti, Silvia Diviccaro, Giancarlo Panzica, Roberto Cosimo Melcangi
Sexual dysfunction is a clinical condition due to different causes including the iatrogenic origin. For instance, it is well known that sexual dysfunction may occur in patients treated with antidepressants like selective serotonin reuptake inhibitors (SSRI). A similar side effect has been also reported during treatment with finasteride, an inhibitor of the enzyme 5alpha-reductase, for androgenetic alopecia. Interestingly, sexual dysfunction persists in both cases after drug discontinuation. These conditions have been named post-SSRI sexual dysfunction (PSSD) and post-finasteride syndrome (PFS)...
April 19, 2018: Endocrine
https://www.readbyqxmd.com/read/29668838/organizational-effects-of-the-antiandrogen-vinclozolin-on-penis-development-in-the-mouse
#3
Ciro M Amato, Morgan Boyd, Joshua Yang, Krista A McCoy
Endocrine disrupting chemicals (EDCs) are pollutants found throughout the environment that disrupt normal endocrine processes. In mice, penis development is thought to be most susceptible to EDCs during a critical developmental window occurring on embryonic days (E) 15.5-17.5. However, androgen signaling begins on E13.5 when Androgen Receptor (AR) protein is found in the genitalia and testosterone is circulating. We hypothesize that disrupting androgen signaling prior to the established critical window sensitizes the penis to future androgen disruption...
April 14, 2018: Biology of Reproduction
https://www.readbyqxmd.com/read/29668507/classification-and-treatment-of-the-adult-buried-penis
#4
Ursula Mirastschijski
In contrast to the concealed penis found in children, the adult buried penis (BP) is associated with obesity or found in patients after massive weight loss. Bariatric patients present with enormous prepubic fat masses into which the penile shaft retracts. As a consequence, urinating problems occur with wetting of the adjacent tissue. Many BP patients are circumcised with recurrence and worsening of the symptoms. In postbariatric patients, the penis is not engulfed into the prepubic tissue. In contrast to highly obese patients, the BP is covered underneath the cutaneous apron...
April 17, 2018: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/29665137/morphological-development-of-baculum-and-forelimb-second-to-fourth-digit-ratio-in-mice
#5
Minami Fuse, Kazuhiko Sawada
The baculum (or os penis) is the non-appendicular osseous tissue owned by nine orders of mammals. In rodents, the baculum consists of three segments derived from developmentally-distinct origins: proximal endochondral, central intramembranous and distal cartilaginous segments (Murakami and Mizuno 1984). This report attempted to assess a contribution of physiological levels of prenatal testosterone to the mouse baculal morphology.
April 17, 2018: Congenital Anomalies
https://www.readbyqxmd.com/read/29663358/a-case-control-study-of-hiv-infection-and-cancer-in-the-era-of-antiretroviral-therapy-in-rwanda
#6
Tharcisse Mpunga, Ariana Znaor, F Regis Uwizeye, Aline Uwase, Cyprien Munyanshongore, Silvia Franceschi, Gary M Clifford
The aim of our study was to assess the association between HIV infection and cancer risk in Rwanda approximately a decade after the introduction of antiretroviral therapy (cART). All persons seeking cancer care at Butaro Cancer Center of Excellence (BCCOE) in Rwanda from 2012 to 2016 were routinely screened for HIV, prior to being confirmed with or without cancer (cases and controls, respectively). Cases were coded according to ICD-O-3 and converted to ICD10. Associations between individual cancer types and HIV were estimated using adjusted unconditional logistic regression...
April 16, 2018: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/29656064/a-prospective-study-of-patient-reported-pain-after-bulbar-urethroplasty
#7
Patrick Evans, Sorena Keihani, Benjamin N Breyer, Bradley A Erickson, James M Hotaling, Sara M Lenherr, Jeremy B Myers
PURPOSE: To understand the prevalence of chronic perineal pain, activity limitations, and patient satisfaction after urethroplasty. METHODS: From 2014-2016, we prospectively enrolled men undergoing urethroplasty for bulbar urethral strictures. Patients, before and after surgery, completed questions from the Core Lower Urinary Tract Symptom Score (CLSS) assessing pain frequency in the bladder and penis/urethra, as well as non-validated questions assessing perineal pain...
April 12, 2018: Urology
https://www.readbyqxmd.com/read/29644193/nonvenereal-penile-dermatoses-a-retrospective-study
#8
Ana Marcos-Pinto, Luís Soares-de-Almeida, João Borges-Costa
Context: A variety of nonvenereal diseases can affect the penis and diminish quality of life. Many present similar clinical features and a cutaneous biopsy may be necessary to clarify the diagnosis. Aims: To characterize nonvenereal penile dermatoses with histological confirmation in a southwestern Europe hospital during a 9-year period. Materials and Methods: A retrospective study was conducted. We reviewed all penile biopsies performed between January 1, 2007 and December 31, 2015 and studied the causes of the nonvenereal penile dermatoses...
March 2018: Indian Dermatology Online Journal
https://www.readbyqxmd.com/read/29644164/the-extra-tunical-grafting-procedure-for-peyronie-s-disease-hourglass-and-indent-deformities
#9
Amanda B Reed-Maldonado, Amjad Alwaal, Tom F Lue
Background: To describe a novel, tunica-sparing surgical technique-extra-tunical grafting (ETG)-for the treatment of penile indent and hourglass (HG) deformities and to describe patient-reported outcomes after the ETG procedure. Methods: An IRB-approved, retrospective chart review of ETG patients was performed to collect data including pre-operative deformity, operation performed, and post-operative patient-reported perception of deformity, erectile function, penile sensation, and overall satisfaction with the ETG operation...
March 2018: Translational Andrology and Urology
https://www.readbyqxmd.com/read/29642341/re-biometry-of-the-hypospadic-penis-after-hormone-therapy-testosterone-and-estrogen-a-randomized-double-blind-controlled-trial
#10
Douglas A Canning
No abstract text is available yet for this article.
April 2018: Journal of Urology
https://www.readbyqxmd.com/read/29627420/exercise-training-causes-a-partial-improvement-through-increasing-testosterone-and-enos-for-erectile-function-in-middle-aged-rats
#11
Dae Yun Seo, Sung Ryul Lee, Hyo Bum Kwak, Hyuntea Park, Kyo Won Seo, Yeon Hee Noh, Kang-Moon Song, Ji-Kan Ryu, Kyung Soo Ko, Byoung Doo Rhee, Jin Han
PURPOSE: Aging changes the balance of sex hormones and causes endothelial dysfunction in the penis, both of which are important determinants of erectile dysfunction (ED). The purpose of this study was to evaluate whether exercise training could protect against erectile dysfunction by increasing serum testosterone and penile eNOS levels in aging rats. METHODS: A total of 14 young (2-month-old) and 14 middle-aged (18-month-old) Sprague Dawley rats were randomly assigned to either untrained control (young control, [YC], middle-aged control, [MC]) or endurance exercise-trained (young exercise, [YE], middle-aged exercise, [ME]) groups with seven rats per group...
April 5, 2018: Experimental Gerontology
https://www.readbyqxmd.com/read/29625136/surgical-management-of-adult-acquired-buried-penis-impact-on-urinary-and-sexual-quality-of-life-outcomes
#12
Katherine M Theisen, Thomas W Fuller, Paul Rusilko
OBJECTIVES: To assess postoperative patient-reported quality of life outcomes following surgical management of adult acquired buried penis (AABP). We hypothesize that surgical treatment of AABP results in improvements in urinary and sexual quality of life. METHODS: Patients that underwent surgical treatment of AABP were retrospectively identified. The Expanded Prostate Cancer Index (EPIC) questionnaire was completed at ≥ 3 months postoperatively, and completed retrospectively to define preoperative symptoms...
April 3, 2018: Urology
https://www.readbyqxmd.com/read/29623703/penile-reconstructive-surgery-in-peyronie-disease-challenges-in-restoring-normal-penis-size-shape-and-function
#13
REVIEW
Eric Chung
PURPOSE: To provide an overview of current approaches to penile reconstructive surgery in Peyronie disease (PD), and to discuss the challenges in restoring normal penile size and function. METHODS: A systematic literature search was conducted to identify the published literature relevant to PD and penile reconstructive surgery. A summary of the published guidelines from major organisations is included in this review paper. DISCUSSION: Penile plication is simple and minimally invasive, and tends to preserve potency in most patients...
March 29, 2018: World Journal of Men's Health
https://www.readbyqxmd.com/read/29623695/a-case-series-of-patients-who-underwent-laparoscopic-extraperitoneal-radical-prostatectomy-with-the-simultaneous-implant-of-a-penile-prosthesis-focus-on-penile-length-preservation
#14
Nicola Mondaini, Tommaso Cai, Enrico Sarti, Gaia Polloni, Andrea Gavazzi, Duccio Conti, Andrea Cocci, Maarten Albersen, Gianmartin Cito, Riccardo Bartoletti
PURPOSE: There are many grey areas in the field of penile rehabilitation after radical prostatectomy (RP). The preservation of the full dimensions of the penis is an important consideration for improving patients' compliance for the treatment. We present the first case series of patients treated by laparoscopic extraperitoneal RP and simultaneous penile prosthesis implantation (PPI) in order to preserve the full length of the penis and to improve patients' satisfaction. MATERIALS AND METHODS: From June 2013 to June 2014, 10 patients underwent simultaneous PPI (with an AMS InhibiZone prosthesis) and RP...
January 26, 2018: World Journal of Men's Health
https://www.readbyqxmd.com/read/29622476/total-penile-reconstruction-a-systematic-review
#15
REVIEW
A Yao, M J Ingargiola, C D Lopez, P Sanati-Mehrizy, N M Burish, E M Jablonka, P J Taub
BACKGROUND: Phalloplasty poses a unique challenge to the plastic and reconstructive surgeon. The development of advanced microsurgical techniques has greatly augmented the range of surgical approaches available. METHODS: A systematic review of the MEDLINE and Cochrane databases was performed to identify clinical studies of total penile reconstruction published within the last 10 years using the search algorithm: "(phallus or penis or penile) and (reconstruction or phalloplasty or transplant)"...
February 14, 2018: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/29619903/healing-of-spongiosus-cutaneous-fistula-with-hyperbaric-oxygen-therapy-hbot-a-case-report
#16
Pier A Della Camera, Gianmartin Cito, Simone Morselli, Francesco Sessa, Davide Facchiano, Andrea Cocci, Mauro Gacci, Sergio Serni, Marco Carini, Alessandro Natali
INTRODUCTION: We present a case of a spongiosus-cutaneous fistula in a 39-year-old man with recurrent episodes of cutaneous abscess in dorsal middle third penis (5 × 3 cm) treated with Hyperbaric Oxygen Therapy (HBOT). CASE REPORT: After emptying nodular abscess, the patient was noncompliant for further surgery. Therefore, it was suggested the association between HBOT and antibiotic therapy. HBOT is carried out in a hyperbaric room, where the internal pressure is increased (compression phase) by entering compressed air up to 283...
February 2018: Urologia
https://www.readbyqxmd.com/read/29619588/autoimmune-inflammatory-syndrome-induced-by-mineral-oil-a-health-problem
#17
Olga Vera-Lastra, Gabriela Medina, María Pilar Cruz-Domínguez, Gabriel Medrano Ramírez, Raymundo Benjamin Priego Blancas, Ana Lilia Peralta Amaro, Anabel Villanueva Martínez, Jesús Sepúlveda Delgado, Luis J Jara
Autoimmune/inflammatory syndrome induced by adjuvant (ASIA) includes the following conditions: siliconosis, Gulf War syndrome, macrophagic myofasciitis syndrome, and post-vaccination phenomena. Afterward, other syndromes have been recognized, such as in ASIA by mineral oil (ASIA-MO). These conditions are triggered by adjuvants and they are the result of the interplay of genetic and environmental factors. ASIA-MO is defined as the infiltration of oily type modeling substances for cosmetic purposes. It has been reported in many countries and used surreptitiously...
April 4, 2018: Clinical Rheumatology
https://www.readbyqxmd.com/read/29619442/comparison-of-multiplex-single-round-pcr-and-microscopy-in-diagnosis-of-amoebiasis
#18
Sri-Hidajati Bs, Sukmawati Basuki, Suhintam Pusarawati, Kusmartisnawati, Lynda Rossyanti, Sri Wijayanti Sulistyowati, Dwi Peni Kartikasari, Heny Arwati, Indah Tantular, Alpha Fardah, Andy Darma, Retno Handajani, Subijanto Marto Soedarmo
Background: Amoebiasis, the cause of dysentery and extra-intestinal abscesses, now becomes second fatal parasitic disease in the world. As routine microscopic diagnosis cannot differentiate causative Entamoeba histolytica from non-pathogenic E. dispar and E. moshkovskii , better diagnosis has to be searched. Materials and Methods: Multiplex single round PCR was tested and compared with results of microscopy of wet preparation on 30 samples of diarrheic stools and extra intestinal lesions from amoebiasis suspected patients...
2018: African Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29617773/females-peer-influence-and-support-for-adolescent-males-receiving-voluntary-medical-male-circumcision-services
#19
Michelle R Kaufman, Kim H Dam, Kriti Sharma, Lynn M Van Lith, Karin Hatzold, Arik V Marcell, Webster Mavhu, Catherine Kahabuka, Lusanda Mahlasela, Eshan U Patel, Emmanuel Njeuhmeli, Kim Seifert Ahanda, Getrude Ncube, Gissenge Lija, Collen Bonnecwe, Aaron A R Tobian
Background: While female involvement in voluntary medical male circumcision (VMMC) has been studied among adults, little is known about the influence of adolescent females on their male counterparts. This study explored adolescent females' involvement in VMMC decision making and the postoperative wound healing process in South Africa, Tanzania, and Zimbabwe. Methods: Across 3 countries, 12 focus group discussions were conducted with a total of 90 adolescent females (aged 16-19 years)...
April 3, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29609831/birth-defects-in-children-of-men-exposed-in-utero-to-diethylstilbestrol-des
#20
Michel Tournaire, Emmanuel Devouche, Sylvie Epelboin, Anne Cabau, Annabel Dunbavand, Anne Levadou
OBJECTIVE: Prenatal exposure to diethylstilbestrol (DES) is associated with adverse effects, including genital anomalies and cancers in men and women. Animal studies showed birth defects and tumors in the offspring of mice prenatally exposed to DES. In humans, birth defects, such as hypospadias were observed in children of prenatally exposed women. The aim of this research was to assess the birth defects in children of prenatally exposed men. METHODS: In a retrospective study conceived by a patients' association (Réseau DES France), the reports of men prenatally exposed to DES on adverse health effects in their children were compared with those of unexposed controls and general population...
March 3, 2018: Thérapie
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