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https://www.readbyqxmd.com/read/29457262/handheld-reflectance-confocal-microscopy-dermatoscopy-and-histopathological-correlation-of-common-inflammatory-balanitis
#1
F Lacarrubba, A E Verzì, M Ardigò, G Micali
BACKGROUND: The term balanitis includes a variety of inflammatory skin diseases involving the glans penis whose clinical diagnosis may be challenging. A biopsy is often required to obtain a definitive diagnosis, although it is barely accepted by patients. Reflectance confocal microscopy (RCM), that provides a real-time, en face imaging of the epidermis and upper dermis, is currently utilized for the diagnosis of some neoplastic and inflammatory skin diseases. The aim of this study was to analyze the RCM handheld findings of some common balanitis and to correlate them with dermatoscopy and histopathological features...
February 18, 2018: Skin Research and Technology
https://www.readbyqxmd.com/read/29447059/therapeutic-potential-of-mucuna-pruriens-linn-on-ageing-induced-damage-in-dorsal-nerve-of-the-penis-and-its-implication-on-erectile-function-an-experimental-study-using-albino-rats
#2
Prakash Seppan, Ibrahim Muhammed, Karthik Ganesh Mohanraj, Ganesh Lakshmanan, Dinesh Premavathy, Sakthi Jothi Muthu, Khayinmi Wungmarong Shimray, Sathya Bharathy Sathyanathan
OBJECTIVE: To study the effect of ethanolic seed extract of Mucuna pruriens on damaged dorsal nerve of the penis (DNP) in aged rat in relation to penile erection. METHODS: The rats were divided into four groups Young (3 months), Aged (24 - 28 months), Aged + M. pruriens, and Young + M. pruriens (200 mg/kg b.w/60 days) and were subjected to the hypophysial - gonadal axis, nerve conduction velocity (NCV), and penile reflex. DNP sections were stained with nitric oxide synthase (nNOS), nicotinamide adenine dinucleotide phosphate (NaDPH) diaphorase, androgen receptor (AR), and osmium tetroxide...
February 15, 2018: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/29444762/hemimegalencephaly-with-bannayan-riley-ruvalcaba-syndrome
#3
Ryan Ghusayni, Monisha Sachdev, William Gallentine, Mohamad A Mikati, Marie T McDonald
Hemimegalencephaly is known to occur in Proteus syndrome, but has not been reported, to our knowledge, in the other PTEN mutation-related syndrome of Bannayan-Riley-Ruvalcaba. Here, we report a patient with Bannayan-Riley-Ruvalcaba syndrome who also had hemimegalencephaly and in whom the hemimegalencephaly was evident well before presentation of the characteristic manifestations of Bannayan-Riley-Ruvalcaba syndrome. An 11-year-old boy developed drug-resistant focal seizures on the fifth day of life. MRI revealed left hemimegalencephaly...
February 14, 2018: Epileptic Disorders: International Epilepsy Journal with Videotape
https://www.readbyqxmd.com/read/29438589/baus-consensus-document-for-the-management-of-male-genital-emergencies-penile-fracture
#4
REVIEW
R W Rees, G Brown, T Dorkin, M Lucky, R Pearcy, M Shabbir, C J Shukla, D J Summerton, A Muneer
Male genital emergencies relating to the penis and scrotum are rare and require prompt investigation and surgical intervention. Clinicians are often unfamiliar with the management of these conditions and may not work in a specialist centre with on-site expertise in genitourethral surgery available. The aim of these consensus statements is to provide a best practice guidance for urological surgeons based in the UK and developed by an expert consensus. Penile fracture is a rare emergency and in the majority of cases requires prompt exploration and repair to prevent erectile dysfunction and penile curvature...
February 13, 2018: BJU International
https://www.readbyqxmd.com/read/29423307/the-importance-of-the-bulbocavernosus-reflex
#5
REVIEW
Jean Gabriel Previnaire
The BCR consists of the contraction of the bulbocavernosus muscle in response to squeezing the glans penis or clitoris, and is mediated through the pudendal nerve. In case of a complete lesion, the presence of BCR is indicative of intact S2-S4 spinal reflex arcs and loss of supraspinal inhibition, determining an upper motor neuron (UMN) lesion, its absence a lower motor neuron (LMN) lesion. The BCR further helps distinguish conus medullaris from cauda equina syndromes. Sensory or motor function in the most caudal sacral segments, not BCR, defines the sacral sparing as part of the International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI)...
2018: Spinal Cord Series and Cases
https://www.readbyqxmd.com/read/29418090/s2k-leitlinie-hpv-assoziierte-l%C3%A3-sionen-der-%C3%A3-u%C3%A3-eren-genitalregion-und-des-anus-genitalwarzen-und-krebsvorstufen-der-vulva-des-penis-und-der-peri-und-intraanalen-haut-kurzfassung
#6
Gerd E Gross, Ricardo N Werner, Jürgen C Becker, Norbert H Brockmeyer, Stefan Esser, Monika Hampl, Sara Hommel, Johannes Jongen, Dominik S Mestel, Thomas Meyer, Karl U Petry, Andreas Plettenberg, Klaus Püschel, Peter Schneede, Helmut Schöfer, Karl Sotlar, Gerhard Weyandt, Ulrike Wieland, Miriam Wiese-Posselt, Alexander Nast
No abstract text is available yet for this article.
February 2018: Journal der Deutschen Dermatologischen Gesellschaft, Journal of the German Society of Dermatology: JDDG
https://www.readbyqxmd.com/read/29418083/s2k-guideline-hpv-associated-lesions-of-the-external-genital-region-and-the-anus-anogenital-warts-and-precancerous-lesions-of-the-vulva-the-penis-and-the-peri-and-intra-anal-skin-short-version
#7
Gerd E Gross, Ricardo N Werner, Jürgen C Becker, Norbert H Brockmeyer, Stefan Esser, Monika Hampl, Sara Hommel, Johannes Jongen, Dominik S Mestel, Thomas Meyer, Karl U Petry, Andreas Plettenberg, Klaus Püschel, Peter Schneede, Helmut Schöfer, Karl Sotlar, Gerhard Weyandt, Ulrike Wieland, Miriam Wiese-Posselt, Alexander Nast
No abstract text is available yet for this article.
February 2018: Journal der Deutschen Dermatologischen Gesellschaft, Journal of the German Society of Dermatology: JDDG
https://www.readbyqxmd.com/read/29416825/prognosis-of-men-with-penile-metastasis-and-malignant-priapism-a-systematic-review
#8
REVIEW
Andrea Cocci, Oliver W Hakenberg, Tommaso Cai, Gabriella Nesi, Lorenzo Livi, Beatrice Detti, Andrea Minervini, Girolamo Morelli, Marco Carini, Sergio Serni, Mauro Gacci
Metastases to the penis are rare, but can have severe consequences. The aim of this study was to systematically review the literature in order to gain more information on the presentation and prognosis of this metastatic disease. We reviewed the literature relating to all case reports, series and reviews about penile metastasis, from 2003 to 2013, through a Medline search. We identified 63 articles and 69 patients. Metastases were located on the root (38.8%), the shaft (38.8%) or the glans (22.2%) of the penis...
January 5, 2018: Oncotarget
https://www.readbyqxmd.com/read/29414500/priapism-as-the-initial-sign-in-hematologic-disease-case-report-and-literature-review
#9
Luis Cuitláhuac Becerra-Pedraza, Luis Enrique Jiménez-Martínez, Iran Peña-Morfin, Rogelio Nava-Esquivel, Juan Alfredo Villegas-Martínez
INTRODUCTION: Priapism is an uncommon sign and sometimes considered a diagnosis challenge into systemic disease; this is defined as ≥4 h continuous penile erection, without sexual stimulation. We state that this work has been reported in line with the SCARE criteria PRESENTATION OF CASE: A Mexican 52-year-old man was brought to the emergency room with priapism of six days of evolution. His medical history reported fatigue and waxy pallor had begun a month ago, the rest of interrogation was unremarked...
January 12, 2018: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29410690/shear-wave-elastography-can-it-be-a-new-radiologic-approach-for-the-diagnosis-of-erectile-dysfunction
#10
Rustu Turkay, Ercan Inci, Mustafa Gurkan Yenice, Volkan Tugcu
Introduction: Erectile dysfunction (ED) is a common health problem among males, and radiology has limited use in its diagnosis and treatment. Shear wave elastography (SWE) is a new sonographic technique. In this study, we examined the significance of SWE in the diagnosis of ED. Methods: The study included a total number of 70 participants. The mean age of the participants was 54.14 ± 8.03 years (range: 39 and 71 years old). We composed two groups. Group 1 had 35 patients who presented to the urology clinic in our hospital complaining of ED, and had a score of 17 or lower from the International Index of Erectile Function (IIEF) questionnaire...
August 2017: Ultrasound: Journal of the British Medical Ultrasound Society
https://www.readbyqxmd.com/read/29408215/the-impact-of-immediate-salvage-surgery-on-corporeal-length-preservation-in-patients-presenting-with-penile-implant-infections
#11
Diana M Lopategui, Raymond R Balise, Layla A Bouzoubaa, Steven K Wilson, Bruce R Kava
PURPOSE: Removal of an infected penile implant often results in corporeal fibrosis, irreversible penile shortening, and dissatisfaction with future implant surgery. Salvage surgery may avoid these problems, but to date no study has evaluated these specific endpoints. Patients presenting to our center with infected implants were evaluated to determine the impact of salvage surgery on penile length. MATERIALS AND METHODS: Consecutive patients undergoing removal of an infected penile prosthesis with either immediate salvage or delayed re-implantation were evaluated using a comprehensive, prospective database...
February 2, 2018: Journal of Urology
https://www.readbyqxmd.com/read/29406065/urologic-emergencies
#12
REVIEW
Adarsh S Manjunath, Matthias D Hofer
Urologic emergencies can involve the kidneys, ureters, bladder, urethra, penis, scrotum, or testicles. History and physical examination are essential to diagnosis, whereas imaging is increasingly used to confirm diagnoses. Acute urinary retention should be relieved with Foley placement. Penile emergencies include paraphimosis, which can be treated by foreskin reduction, whereas penile fracture and priapism require urologic intervention. Fournier gangrene and testicular torsion are scrotal emergencies requiring emergent surgery...
March 2018: Medical Clinics of North America
https://www.readbyqxmd.com/read/29403152/adrenocortical-carcinoma-characterized-by-gynecomastia-a-case-report
#13
Takako Takeuchi, Yuko Yoto, Akira Ishii, Takeshi Tsugawa, Masaki Yamamoto, Tsukasa Hori, Hotaka Kamasaki, Kazutaka Nogami, Takanori Oda, Akihiro Nui, Sachiko Kimura, Takuya Yamagishi, Keiko Homma, Tomonobu Hasegawa, Maki Fukami, Yoko Watanabe, Hidehiko Sasamoto, Hiroyuki Tsutsumi
We present a 4-yr-old boy with adrenocortical carcinoma (ACC), diagnosed due to the appearance of gynecomastia as the presenting symptom. Six months prior to admission, an acute growth spurt along with the development of bilateral breast swelling was observed. He did not present any features of virilization, including enlargement of the testes, increase in testis volume, and penis size. Laboratory investigations showed gonadotropin-independent hypergonadism, with low LH/ FSH levels and elevated estradiol/testosterone levels...
2018: Clinical Pediatric Endocrinology: Case Reports and Clinical Investigations: Official Journal of the Japanese Society for Pediatric Endocrinology
https://www.readbyqxmd.com/read/29394981/isolated-involvement-of-penis-in-fournier-s-gangrene-a-rare-possibility
#14
Partha Pratim Deb, Arpan Choudhary, Ranjan Kumar Dey, Ranjit Kumar Das
skin and subcutaneous tissue. Penis may be secondarily affected in some cases; however, primary isolated involvement of penis is rare. A 48-year male smoker presented with pain and blackish discoloration of the distal part of penis for the last 4 days which developed following rupture of a papulo-vesicular lesion over the prepuce of penis. It rapidly progressed to involve half of the skin of the penis. The patient was hospitalized and broad spectrum antibiotics were administered parenterally. Emergency wound debridement and urinary diversion by suprapubic cystostomy was done...
February 2018: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/29394072/molecular-profile-of-priapism-associated-with-low-nitric-oxide-bioavailability
#15
Justin D La Favor, Zongming Fu, Vidya Venkatraman, Trinity J Bivalacqua, Jennifer E Van Eyk, Arthur L Burnett
Priapism is a disorder in which prolonged penile erection persists uncontrollably, potentially leading to tissue damage. Priapism commonly afflicts patient populations with severely low nitric oxide (NO) bioavailability. As NO is a primary mediator of erection, the molecular mechanisms involved in priapism pathophysiology associated with low NO bioavailability are not well understood. The objective of this study was to identify dysregulated molecular targets and signaling pathways in penile tissue of a mouse model of low NO bioavailability that have potential relevance to priapism...
February 2, 2018: Journal of Proteome Research
https://www.readbyqxmd.com/read/29393077/warty-squamous-cell-carcinoma-of-glans-penis
#16
Tasleem Arif, Mohammad Adil, Noora Saeed
No abstract text is available yet for this article.
February 1, 2018: Indian Journal of Dermatology, Venereology and Leprology
https://www.readbyqxmd.com/read/29387560/successful-removal-of-a-penoscrotal-constricting-ring-in-a-49-year-old-male
#17
Yadong Lu, Teck-Wei Tan, Ko Weber Lau
Placement of constricting devices around the penis and scrotum for autoerotic purposes or increasing sexual performance represents a well-known challenge for urologists and can result in serious complications. The removal of the constricting devices can be challenging and often requires resourcefulness and multidisciplinary approach. We report one case of successful removal of a penoscrotal constricting metal ring in a 49-year-old male using a hand-held orthopaedic saw under ketamine and midazolam sedation in the emergency department...
October 2017: Asian Journal of Urology
https://www.readbyqxmd.com/read/29375780/the-baubellum-is-more-developmentally-and-evolutionarily-labile-than-the-baculum
#18
Michael Lough-Stevens, Nicholas G Schultz, Matthew D Dean
Understanding the evolutionary forces that influence sexual dimorphism is a fundamental goal in biology. Here, we focus on one particularly extreme example of sexual dimorphism. Many mammal species possess a bone in their penis called a baculum. The female equivalent of this bone is called the baubellum and occurs in the clitoris, which is developmentally homologous to the male penis. To understand the potential linkage between these two structures, we scored baculum/baubellum presence/absence across 163 species and analyzed their distribution in a phylogenetic framework...
January 2018: Ecology and Evolution
https://www.readbyqxmd.com/read/29373631/physiological-and-anatomical-outputs-of-rat-genital-cortex
#19
Constanze Lenschow, Michael Brecht
Rat somatosensory genital cortex contains a large sexually monomorphic representation of the penis in males and the clitoris in females. Genital cortex microstimulation-evoked movements of legs, trunk and genitals, which showed sex-specific differences related to mating behaviors and included thrusting in males and lordosis-like movements in females. Erections/tumescence of penis or clitoris could not be evoked, however. Anterograde tracer injections into penis/clitoris cortex revealed eleven corticocortical and 10 subcortical projection targets, which were qualitatively similar in both sexes...
January 24, 2018: Cerebral Cortex
https://www.readbyqxmd.com/read/29373264/disseminated-fusariosis-emerged-from-prolonged-local-genital-infection-after-cord-blood-transplantation
#20
Kohei Okada, Tomoyuki Endo, Daigo Hashimoto, Tomoyuki Saga, Takahide Ara, Reiki Ogasawara, Atsushi Yasumoto, Makoto Ibata, Mutsumi Takahata, Akio Shigematsu, Takeshi Kondo, Yasunori Muraosa, Toshifumi Nomura, Hiromi Kanno-Okada, Satoshi Hashino, Shinya Tanaka, Katsuhiko Kamei, Takanori Teshima
Disseminated fusariosis (DF) is a rare life threatening fungal infection in immunocompromised hosts. We herein report a case of a fatal DF mimicking varicella zoster virus (VZV) infection that was emerged from a localized genital infection during cord blood transplantation (CBT) in a patient with severe aplastic anemia (SAA). The patient developed an ulcer following small painful vesicles mimics herpes simplex virus infection (HSV) on the glans penis before CBT, but a Fusarium species was identified. Despite administration of voriconazole, liposomal amphotericin B and granulocyte transfusion, the lesion was extended to extensive skin looked like VZV infection and the patients died after CBT...
January 16, 2018: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
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