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Pregnancy infection

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https://www.readbyqxmd.com/read/29792359/adverse-effect-analysis-of-high-intensity-focused-ultrasound-in-the-treatment-of-benign-uterine-diseases
#1
Yunchang Liu, Wendy Wenyi Zhang, Min He, Chunmei Gong, Bin Xie, Xiangxia Wen, Dandan Li, Lian Zhang
OBJECTIVE: To retrospectively analyze the adverse effects of high-intensity focused ultrasound (HIFU) in management of benign uterine diseases. MATERIALS AND METHODS: From 2011 to 2017, 27,053 patients with benign uterine diseases were treated with HIFU in 19 centers in China. Among them, 17,402 patients had uterine fibroids, 8434 had adenomyosis, 876 had caesarean scar pregnancies, and 341 had placenta accreta. RESULTS: The median age, height, weight, BMI of the patients was 42 years, 158 mm, 56 kg, 22...
May 24, 2018: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/29789240/effect-of-maternal-immunization-against-pertussis-in-medellin-and-the-metropolitan-area-colombia-2016-2017
#2
Doracelly Hincapié-Palacio, María Cristina Hoyos, Jesus Ochoa, Nilton Montoya, Diego García, Elkin Osorio
BACKGROUND: In 2013, pertussis immunization (Tdap) for pregnant women was implemented in Colombia to protect newborns in response to increased pertussis incidence. OBJECTIVE: To assess the effect of Tdap maternal immunization on the concentration of mother/umbilical cord antibodies and the occurrence of pertussis in infants during their first six months of life. METHODS: A cohort study in eight randomly selected hospitals in Medellin and metropolitan area of Antioquia, Colombia was conducted in 2015-2016...
May 19, 2018: Vaccine
https://www.readbyqxmd.com/read/29788108/porphyromonas-gingivalis-strain-dependent-inhibition-of-uterine-spiral-artery-remodeling-in-the-pregnant-rat
#3
P Phillips, M B Brown, A Progulske-Fox, X J Wu, L Reyes
Porphyromonas gingivalis (Pg), is an important periodontal pathogen that is also implicated in pregnancy complications involving defective deep placentation (DDP). We hypothesized that Pg invasion of the placental bed promotes DDP. Pregnant rats were intravenously inoculated with sterile vehicle, Pg strain W83, or A7436 at gestation day (GD) 14 (acute cohort). Non-pregnant rats received repeated oral inoculations for 3 months before breeding (chronic cohort). Tissues and/or sera were collected at GD18 for analysis...
May 18, 2018: Biology of Reproduction
https://www.readbyqxmd.com/read/29787622/mother-to-child-transmission-of-hiv-in-australia-and-other-high-income-countries-trends-in-perinatal-exposure-demography-and-uptake-of-prevention-strategies
#4
REVIEW
Kelly O'Donovan, Theophilus I Emeto
Virtual elimination of mother-to-child transmission (MTCT) of human immunodeficiency virus (HIV) is a global target. A review of the literature was conducted using medical databases and health department websites to examine the current trends related to perinatal HIV exposure and MTCT in Australia in comparison with other high-income countries (HICs). The review discusses the uptake of prevention strategies and barriers that impede MTCT prevention. The literature suggests an increase in the numbers of HIV-exposed deliveries, but a marked decline in the rates of MTCT within HICs...
May 22, 2018: Australian & New Zealand Journal of Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/29786583/incidence-and-risk-factors-of-spina-bifida-in-children
#5
Mariana O Ryznychuk, Mariana I Kryvchanska, Irina V Lastivka, Roman Ye Bulyk
OBJECTIVE: Introduction: The pathogenesis of spina bifida depends on time, region, race and ethnicity. It is found in 4.7 per 10.000 of live born children worldwide. The aim: The incidence in children of Northern Bukovina was analyzed. The spina bifida incidence for 2007-2016 in this region, as well as, compared to some countries according to EUROCAT data was studied. PATIENTS AND METHODS: Materials and methods: A retrospective study to analyze the risk factors for spina bifida was carried out...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29785877/hepatitis-b-virus-lymphotropism-emerging-details-and-challenges
#6
Shivali S Joshi, Carla S Coffin
The hepatitis B virus (HBV) is predominantly a hepatotropic virus but also infects cells of the lymphatic system. HBV genomes (DNA, messenger (m)RNA, covalently closed circular (ccc) DNA) and proteins have been found in extrahepatic sites such as peripheral blood mononuclear cells (PBMC), lymph nodes, spleen, bone marrow and cerebrospinal fluid. HBV entry into hepatocytes occurs by binding of the HBV preS1 surface protein to its specific receptor, the bile acid transporter, sodium taurocholate co-transporting polypeptide (NTCP)...
May 22, 2018: Biotechnology & Genetic Engineering Reviews
https://www.readbyqxmd.com/read/29785387/parvovirus-b19-infection-timely-diagnosis-in-pregnancy-essential
#7
REVIEW
G J Waring
No abstract text is available yet for this article.
April 2018: Case Reports in Women's Health
https://www.readbyqxmd.com/read/29784859/igg-responses-to-the-plasmodium-falciparum-antigen-var2csa-in-colombia-are-restricted-to-pregnancy-and-are-not-induced-by-exposure-to-p-vivax
#8
Mary Lopez-Perez, Mads Delbo Larsen, Rafael Bayarri-Olmos, Paulina Ampomah, Liz Stevenson, Myriam Arévalo-Herrera, Sócrates Herrera, Lars Hviid
Clinical immunity to malaria is associated with acquisition of IgG specific for members of the Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) family of clonally variant antigens on the surface of infected erythrocytes (IEs). The VAR2CSA subtype of PfEMP1 mediates IE binding in the placenta. VAR2CSA-specific IgG is normally acquired only after exposure to placental parasites. However, it was recently reported that men and children from Colombia often have high levels of functional VAR2CSA-specific IgG...
May 21, 2018: Infection and Immunity
https://www.readbyqxmd.com/read/29784112/technology-based-interventions-to-reduce-sexually-transmitted-infections-and-unintended-pregnancy-among-youth
#9
REVIEW
Laura Widman, Jacqueline Nesi, Kristyn Kamke, Sophia Choukas-Bradley, J L Stewart
PURPOSE: Technology-based interventions to promote sexual health have proliferated in recent years, yet their efficacy among youth has not been meta-analyzed. This study synthesizes the literature on technology-based sexual health interventions among youth. METHODS: Studies were included if they (1) sampled youth ages 13-24; (2) utilized technology-based platforms; (3) measured condom use or abstinence as outcomes; (4) evaluated program effects with experimental or quasi-experimental designs; and (5) were published in English...
June 2018: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
https://www.readbyqxmd.com/read/29783825/-clinical-and-molecular-analysis-of-two-chinese-siblings-with-bloom-syndrome
#10
M L Wu, X M Wang, J Li, Y Ding, Y Chen, G Y Chang, J Wang, Y P Shen
Objective: To expand the knowledge of the clinical and molecular characteristics of the children with Bloom syndrome. Methods: Clinical data of two siblings with classic Bloom syndrome of Shanghai Children's Medical Center from January 2009 to June 2017 were obtained and analyzed. The DNA of peripheral blood was collected from two Bloom syndrome siblings and their parents during 2015. The mutations were detected with high-throughput sequencing by Illumina sequencing platform. Results: The two siblings (probands) visited our department for short stature and growth retardation, they had full-term normal delivery after normal pregnancy of their mother...
May 2, 2018: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://www.readbyqxmd.com/read/29782302/reasons-for-not-using-condoms-among-heterosexual-men-in-belgrade-serbia
#11
Milan Bjekić, Sandra Sipetić-Grujičić, Hristina Vlajinac, Aleksandra Nikolić
Dear Editor, Proper and consistent use of male condoms can be a highly effective method of preventing the transmission of sexually transmitted infections (STIs) and HIV (1), but this method relies on men's willingness and ability to use condoms. In the United States of America, about 20% overall and less than 50% of adults with multiple partners used a condom at last intercourse (2). In Serbia in 2013 (3), 50.0% of women and 62.5% of men aged 15-49 who had more than one partner in the past year used a condom during their last intercourse...
April 2018: Acta Dermatovenerologica Croatica: ADC
https://www.readbyqxmd.com/read/29780421/umbilical-cord-hematoma-a-case-report-and-review-of-the-literature
#12
REVIEW
Gennaro Scutiero, Bernardi Giulia, Piergiorgio Iannone, Luigi Nappi, Danila Morano, Pantaleo Greco
Objectives: To deepen the knowledge in obstetrics on a very rare pregnancy complication: umbilical cord hematoma. Methods: A review of the case reports described in the last ten years in the literature was conducted in order to evaluate epidemiology, predisposing factors, potential outcomes, prenatal diagnosis, and clinical management. Results: Spontaneous umbilical cord hematoma is a rare complication of pregnancy which represents a serious cause of fetal morbidity and mortality...
2018: Obstetrics and Gynecology International
https://www.readbyqxmd.com/read/29779827/zika-virus-report-from-the-task-force-on-tropical-diseases-by-the-world-federation-of-societies-of-intensive-and-critical-care-medicine
#13
Gisele Sampaio Silva, Guy A Richards, Tim Baker, Jorge Hidalgo, Juan Ignacio Silesky Jiménez, Pravin Amin
Zika fever is an acute infectious disease caused by the Zika virus (ZIKV), an RNA virus belonging to the genus Flavivirus. ZIKV can be transmitted by bites from Aedes aegypti and Aedes albopictus species, sexual activity, blood transfusion and from mother to fetus during pregnancy and delivery. A total of 50 territories and countries in the Americas had reported ZIKV infections. For those with symptoms, the presentation is similar to dengue fever with body aches, joint pain, fatigue, malaise, fever and conjunctivitis lasting up to seven days...
April 5, 2018: Journal of Critical Care
https://www.readbyqxmd.com/read/29779260/fifteen-years-of-pmtct-hiv-and-syphilis-outcomes-in-haiti-from-monotherapy-to-option-b
#14
Marie Marcelle Deschamps, Deanna Jannat-Khah, Vanessa Rouzier, Jerry Bonhomme, Julma Pierrot, Myung Hee Lee, Elaine Abrams, Jean Pape, Margaret L McNairy
OBJECTIVE: To evaluate mother and infant outcomes in the largest prevention of mother-to-child-transmission (PMTCT) program in Haiti in order to identify gaps towards elimination of HIV and syphilis. METHODS: Based on retrospective data from HIV+ pregnant women and their infants enrolled in PMTCT care from 1999-2014, we assessed maternal enrolment in PMTCT, receipt of antiretrovirals before delivery, maternal retention through delivery, as well as infant enrolment in PMTCT, HIV testing, and HIV infection...
May 19, 2018: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/29776928/enrichment-of-clinically-relevant-organisms-in-spontaneous-preterm-delivered-placenta-and-reagent-contamination-across-all-clinical-groups-in-a-large-uk-pregnancy-cohort
#15
Lydia J Leon, Ronan Doyle, Ernest Diez-Benavente, Taane G Clark, Nigel Klein, Philip Stanier, Gudrun E Moore
In this study differences in the placental microbiota of term and preterm deliveries from a large UK pregnancy cohort were studied using 16S targeted amplicon sequencing. The impact of contamination from DNA extraction, PCR reagents, as well as those from delivery itself were also examined. A total of 400 placental samples from 256 singleton pregnancies were analysed and differences investigated between spontaneous preterm, non-spontaneous preterm, and term delivered placenta. DNA from recently delivered placenta was extracted, and screening for bacterial DNA was carried out using targeted sequencing of the 16S rRNA gene on the Illumina MiSeq platform...
May 18, 2018: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/29774074/placenta-specific-drug-delivery-by-trophoblast-targeted-nanoparticles-in-mice
#16
Baozhen Zhang, Lunbo Tan, Yan Yu, Baobei Wang, Zhilong Chen, Jinyu Han, Mengxia Li, Jie Chen, Tianxia Xiao, Balamurali K Ambati, Lintao Cai, Qing Yang, Nihar R Nayak, Jian Zhang, Xiujun Fan
Rationale: The availability of therapeutics to treat pregnancy complications is severely lacking, mainly due to the risk of harm to the fetus. In placental malaria, Plasmodium falciparum- infected erythrocytes (IEs) accumulate in the placenta by adhering to chondroitin sulfate A (CSA) on the surfaces of trophoblasts. Based on this principle, we have developed a method for targeted delivery of payloads to the placenta using a synthetic placental CSA-binding peptide (plCSA-BP) derived from VAR2CSA, a CSA-binding protein expressed on IEs...
2018: Theranostics
https://www.readbyqxmd.com/read/29773977/journey-to-the-center-of-the-fetal-brain-environmental-exposures-and-autophagy
#17
REVIEW
Jun Lei, Pilar Calvo, Richard Vigh, Irina Burd
Fetal brain development is known to be affected by adverse environmental exposures during pregnancy, including infection, inflammation, hypoxia, alcohol, starvation, and toxins. These exposures are thought to alter autophagy activity in the fetal brain, leading to adverse perinatal outcomes, such as cognitive and sensorimotor deficits. This review introduces the physiologic autophagy pathways in the fetal brain. Next, methods to detect and monitor fetal brain autophagy activity are outlined. An additional discussion explores possible mechanisms by which environmental exposures during pregnancy alter fetal brain autophagy activity...
2018: Frontiers in Cellular Neuroscience
https://www.readbyqxmd.com/read/29773406/dynamics-of-helicobacter-pylori-infection-in-infants-during-the-first-six-months-of-life
#18
José S Merino, Liliana Araneda, Paulina Lincoñir-Campos, Cristian Parra, Katia Sáez, Apolinaria García
INTRODUCTION: Mainly due to the high percentage of infection and the ineffectiveness of treatments, Helicobacter pylori is a global health problem. Knowing the age at acquisition is key to preventing the infection. PATIENTS: Sixty-seven mothers and their respective children participated. To evaluate the presence of H. pylori, the faeces of the mother and her child were analysed using the HpSA antigen test. RESULTS: 71.6% (48/67) of pregnant mothers were positive for H...
May 14, 2018: Enfermedades Infecciosas y Microbiología Clínica
https://www.readbyqxmd.com/read/29772814/chronic-and-occult-hepatitis-b-virus-infection-in-pregnant-women-in-botswana
#19
Tshepiso Mbangiwa, Ishmael Kasvosve, Motswedi Anderson, Prisca K Thami, Wonderful T Choga, Austen Needleman, Bonolo B Phinius, Sikhulile Moyo, Melvin Leteane, Jean Leidner, Jason T Blackard, Gloria Mayondi, Betsy Kammerer, Rosemary M Musonda, Max Essex, Shahin Lockman, Simani Gaseitsiwe
The hepatitis B virus (HBV) is a global problem; however, the burden of HBV infection in pregnant women in Botswana is unknown. We sought to determine the prevalence of chronic and occult HBV infection in human immunodeficiency virus (HIV)-infected and -uninfected pregnant women in Botswana. Samples from 752 pregnant women were tested for hepatitis B surface antigen (HBsAg), and HBsAg-positive samples were tested for hepatitis B e antigen (HBeAg) and HBV DNA load. Samples that were HBsAg negative were screened for occult HBV infection by determining the HBV DNA load...
May 17, 2018: Genes
https://www.readbyqxmd.com/read/29771574/is-adding-maternal-vaccination-to-prevent-whooping-cough-cost-effective-in-australia
#20
Laure-Anne Van Bellinghen, Alex Dimitroff, Michael Haberl, Xiao Li, Andrew Manton, Karen Moeremans, Nadia Demarteau
Pertussis or whooping cough, a highly infectious respiratory infection, causes significant morbidity and mortality in infants. In adolescents and adults, pertussis presents with atypical symptoms often resulting in under-diagnosis and under-reporting, increasing the risk of transmission to more vulnerable groups. Maternal vaccination against pertussis protects mothers and newborns. This evaluation assessed the cost-effectiveness of adding maternal dTpa (reduced antigen diphtheria, Tetanus, acellular pertussis) vaccination to the 2016 nationally-funded pertussis program (DTPa [Diphtheria, Tetanus, acellular Pertussis] at 2, 4, 6, 18 months, 4 years and dTpa at 12-13 years) in Australia...
May 17, 2018: Human Vaccines & Immunotherapeutics
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