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https://www.readbyqxmd.com/read/27508841/-op-7c-09-coffee-smoking-habits-and-blood-pressure-in-the-light-of-a-single-nucleotide-polimorphysm-of-cyp1a1-1a2-gene
#1
A Tagetti, U Ericson, M Montagnana, P Almgren, P M Nilsson, G Engstrom, B Hedblad, P Minuz, M Orho-Melander, O Melander, C Fava
OBJECTIVE: Between genetic variants pinpointed in genome wide association study there is the rs1378942 near the CYP1A1/CYP1A2 locus. Coffee consumption has been associated with blood pressure (BP) but with sometimes contrasting evidences. A part of BP-coffee relationship could be mediated by genetic mechanisms: that is single nucleotide polymorphisms (SNPs) nearby the CYP1A2 gene, which metabolize caffeine, could influence BP. Indeed, smoking habit induces the expression of the CYP1A2 enzyme whereas coffee consumption itself could increase CYP1A2 activity...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27087403/secondary-fracture-prevention-needs-to-happen-in-the-country-too-the-first-two-and-a-half-years-of-the-coffs-fracture-prevention-clinic
#2
Sandy Fraser, Peter K K Wong
OBJECTIVE: To report the initial two and a half years' experience of one of the first Fracture Liaison Services in regional Australia. DESIGN: Case study. SETTING: Hospital Clinic, mid-north coast NSW. PARTICIPANTS: Patients aged ≥50 years with a fragility fracture identified at Coffs Harbour Health Campus July 2012 to December 2014. INTERVENTION: Patients were identified by a Fracture Liaison Coordinator (FLC) and seen in Fracture Prevention Clinic (FPC) by a rheumatologist...
April 18, 2016: Australian Journal of Rural Health
https://www.readbyqxmd.com/read/26025618/prevalence-of-vocal-tract-discomfort-in-the-flemish-population-without-self-perceived-voice-disorders
#3
Anke Luyten, Laura Bruneel, Iris Meerschman, Evelien D'haeseleer, Mara Behlau, Camille Coffé, Kristiane Van Lierde
OBJECTIVES: The main aim of this study was to assess the prevalence of Vocal Tract Discomfort (VTD) in the Flemish population without self-perceived voice disorders using the VTD scale and to examine the relationship between vocal load and VTD symptoms. In addition, consistency between the VTD scale and the Voice Handicap Index (VHI) and the Corporal Pain scale was evaluated. METHODS: A total of 333 participants completed the VTD scale, the VHI, and the Corporal Pain scale...
May 2016: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/25565776/coffee-and-caffeine-potentiate-the-antiamyloidogenic-activity-of-melatonin-via-inhibition-of-a%C3%AE-oligomerization-and-modulation-of-the-tau-mediated-pathway-in-n2a-app-cells
#4
Li-Fang Zhang, Zhi-Wei Zhou, Zhen-Hai Wang, Yan-Hui Du, Zhi-Xu He, Chuanhai Cao, Shu-Feng Zhou
There is an increasing prevalence of Alzheimer's disease (AD), which has become a public health issue. However, the underlying mechanisms for the pathogenesis of AD are not fully understood, and the current therapeutic drugs cannot produce acceptable efficacy in AD patients. Previous animal studies have shown that coffee (Coff), caffeine (Caff), and melatonin (Mel) have beneficial effects on AD. Disturbed circadian rhythms are observed in AD, and chronotherapy has shown promising effects on AD. In this study, we examined whether a combination of Coff or Caff plus Mel produced a synergistic/additive effect on amyloid-β (Aβ) generation in Neuro-2a (N2a)/amyloid precursor protein (APP) cells and the possible mechanisms involved...
2015: Drug Design, Development and Therapy
https://www.readbyqxmd.com/read/25437024/how-well-do-patients-understand-written-instructions-health-literacy-assessment-in-rural-and-urban-rheumatology-outpatients
#5
Peter K K Wong, Laura Christie, Jenny Johnston, Alison Bowling, Diane Freeman, Fred Joshua, Paul Bird, Karen Chia, Hanish Bagga
The aim of this study was to assess health literacy (word recognition and comprehension) in patients at a rural rheumatology practice and to compare this to health literacy levels in patients from an urban rheumatology practice.Inclusion criteria for this cross-sectional study were as follows: ≥18-year-old patients at a rural rheumatology practice (Mid-North Coast Arthritis Clinic, Coffs Harbour, Australia) and an urban Sydney rheumatology practice (Combined Rheumatology Practice, Kogarah, Australia). Exclusion criteria were as follows: ill-health precluding participation; poor vision/hearing, non-English primary language...
November 2014: Medicine (Baltimore)
https://www.readbyqxmd.com/read/25075672/effect-of-coffee-and-a-cola-based-soft-drink-on-the-color-stability-of-bleached-bovine-incisors-considering-the-time-elapsed-after-bleaching
#6
Rodrigo Pirolo, Rafael Francisco Lia Mondelli, Gisele Maria Correr, Carla Castiglia Gonzaga, Adilson Yoshio Furuse
UNLABELLED: There is no consensus about the waiting time necessary for the patient to start consuming beverages containing colorants again after bleaching. OBJECTIVE: To evaluate the influence of beverages with coloring agents on bleached bovine incisors considering the time elapsed after bleaching. MATERIALS AND METHODS: Sixty bovine incisors were bleached with 35% hydrogen peroxide for in-office use (Whiteness HP Max) and divided into 10 groups...
November 2014: Journal of Applied Oral Science: Revista FOB
https://www.readbyqxmd.com/read/24299440/improving-osteoporosis-management-following-minimal-trauma-fracture-in-a-regional-setting-the-coffs-fracture-card-project
#7
Cheryl Tulk, Pam Lane, Anne Gilbey, Helena Johnston, Karen Chia, Lee Mitchell, Hanish Bagga, Peter K K Wong
OBJECTIVES: To improve osteoporosis (OSP) management following minimal trauma fracture (MTF) with few additional resources. DESIGN: Population intervention with serial cross-sectional analysis. SETTING: Regional setting involving primary care, base hospital and private hospital. PARTICIPANTS: Patients with MTF. INTERVENTION: A 'Fracture Card' prompting OSP management was provided to all patients post-MTF...
December 2013: Australian Journal of Rural Health
https://www.readbyqxmd.com/read/23837920/epiplasmins-and-epiplasm-in-paramecium-the-building-of-a-submembraneous-cytoskeleton
#8
Anne Aubusson-Fleury, Geneviève Bricheux, Raghida Damaj, Michel Lemullois, Gérard Coffe, Florence Donnadieu, France Koll, Bernard Viguès, Philippe Bouchard
In ciliates, basal bodies and associated appendages are bound to a submembrane cytoskeleton. In Paramecium, this cytoskeleton takes the form of a thin dense layer, the epiplasm, segmented into regular territories, the units where basal bodies are inserted. Epiplasmins, the main component of the epiplasm, constitute a large family of 51 proteins distributed in 5 phylogenetic groups, each characterized by a specific molecular design. By GFP-tagging, we analyzed their differential localisation and role in epiplasm building and demonstrated that: 1) The epiplasmins display a low turnover, in agreement with the maintenance of an epiplasm layer throughout the cell cycle; 2) Regionalisation of proteins from different groups allows us to define rim, core, ring and basal body epiplasmins in the interphase cell; 3) Their dynamics allows definition of early and late epiplasmins, detected early versus late in the duplication process of the units...
July 2013: Protist
https://www.readbyqxmd.com/read/23520129/pyrosequencing-assessment-of-prokaryotic-and-eukaryotic-diversity-in-biofilm-communities-from-a-french-river
#9
Geneviève Bricheux, Loïc Morin, Gwenaël Le Moal, Gérard Coffe, Damien Balestrino, Nicolas Charbonnel, Jacques Bohatier, Christiane Forestier
Despite the recent and significant increase in the study of aquatic microbial communities, little is known about the microbial diversity of complex ecosystems such as running waters. This study investigated the biodiversity of biofilm communities formed in a river with 454 Sequencing™. This river has the particularity of integrating both organic and microbiological pollution, as receiver of agricultural pollution in its upstream catchment area and urban pollution through discharges of the wastewater treatment plant of the town of Billom...
June 2013: MicrobiologyOpen
https://www.readbyqxmd.com/read/23494484/food-and-health-individual-cultural-or-scientific-matters
#10
Karin Nordström, Christian Coff, Håkan Jönsson, Lennart Nordenfelt, Ulf Görman
In personalized nutrition, food is a tool for good health, implying an instrumental relationship between food and health. Food receives a secondary value, while health would appear to be a descriptive biological concept. This article gives an introduction to cultural understandings of food and health. The wider definition of food and health is explored in relation to the commonly used scientific approach that tends to take a more reductionist approach to food and health. The different discourses on food and health are being discussed in relation to ethical aspects of personalized nutrition...
July 2013: Genes & Nutrition
https://www.readbyqxmd.com/read/23200532/characterization-and-evolution-of-natural-aquatic-biofilm-communities-exposed-in-vitro-to-herbicides
#11
Geneviève Bricheux, Gwenaël Le Moal, Claire Hennequin, Gérard Coffe, Florence Donnadieu, Christophe Portelli, Jacques Bohatier, Christiane Forestier
River biofilms are assemblies of autotrophic and heterotrophic microorganisms that can be affected by pollutants such as those found in watersheds and wastewater treatment plants. In the laboratory, experimental biofilms were formed from river water, and their overall composition was investigated. Denaturing gradient gel electrophoresis (DGGE) and cytometry were used to assess the richness and diversity of these communities. The software Cytostack (available on request) was developed to treat and analyze the cytometric data...
February 2013: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/22707845/how-friendship-network-characteristics-influence-subjective-well-being
#12
Mariska van der Horst, Hilde Coffé
This article explores how friendship network characteristics influence subjective well-being (SWB). Using data from the 2003 General Social Survey of Canada, three components of the friendship network are differentiated: number of friends, frequency of contact, and heterogeneity of friends. We argue that these characteristics shape SWB through the benefits they bring. Benefits considered are more social trust, less stress, better health, and more social support. Results confirm that higher frequency of contacts and higher number of friends, as well as lower heterogeneity of the friendship network are related to more social trust, less stress, and a better health...
July 2012: Social Indicators Research
https://www.readbyqxmd.com/read/22130970/high-resolution-mapping-of-candidate-alleles-for-desiccation-resistance-in-drosophila-melanogaster-under-selection
#13
Marina Telonis-Scott, Madeleine Gane, Sarah DeGaris, Carla M Sgrò, Ary A Hoffmann
The ability to counter periods of low humidity is an important determinant of distribution range in Drosophila. Climate specialists with low physiological tolerance to desiccation stress are restricted to the tropics and may lack the ability to further increase resistance through evolution. Although the physiological adaptations to desiccation stress are well studied in Drosophila and other ectotherms, factors underlying evolutionary responses remain unknown because of a paucity of genetic data. We address this issue by mapping evolutionary shifts in D...
May 2012: Molecular Biology and Evolution
https://www.readbyqxmd.com/read/21516140/gender-gaps-in-political-participation-across-sub-saharan-african-nations
#14
Hilde Coffe, Catherine Bolzendahl
A substantial literature has studied gender differences in political participation in Western industrialized democracies, but little is known about such gaps in sub-Saharan African nations. Using 2005 Afrobarometer data, this paper presents a systematic investigation of the gender gap in political participation across 18 sub-Saharan African countries. In line with cultural isomorphism, patterns in gender gaps across different types of participation generally mirror those of Western democracies, with small to no gender gaps in registration to vote, but substantial gaps in less institutionalized types of participation...
June 2011: Social Indicators Research
https://www.readbyqxmd.com/read/21466968/-predonation-interview-by-a-trained-and-authorized-paramedical-staff-feasibility-reliability-and-safety
#15
MULTICENTER STUDY
C Coffe, B Romieu, C Adjou, B Giraudeau, B Bastard, B Danic, B Pelletier
INTRODUCTION: Predonation interview accounts for a major step in transfusion safety. In France, it must be performed by a physician, following a methodical questioning and a standardized questionnaire. Faced with this evolution, the value of a strictly medical expertise has been progressively losing importance. In many countries, blood donor selection is being organized by non medical trained staff (Québec, Switzerland, e.g.). A decree of April 30, 2006 allowed the Établissement français du sang to experiment a predonation interview by an authorized paramedical staff in the form of a two-phase prospective multicenter study over a year...
April 2011: Transfusion Clinique et Biologique: Journal de la Société Française de Transfusion Sanguine
https://www.readbyqxmd.com/read/21280311/-morphological-variations-of-the-nuclear-apparatus-of-astome-ciliates-almophrya-bivacuolata-and-a-maediovacuolata-protozoa-ciliophora-endocommensal-of-terricolous-oligochaetes-in-cameroon
#16
P A Nana, P Ngassam, Z Fokam, G Bricheux, P Bouchard, G Coffe, Gando T Sime, Togouet S H Zébazé
The silver impregnation supplemented by DAPI and Feulgen nuclear coloration enabled us to study the morphological variations of the nuclear apparatus of two species of endocommensal Astome ciliates, Almophrya bivacuoloata (de Puytorac & Dragesco, 1968) and A. mediovocuolata (Ngassam, 1983). We highlighted important digitations and the presence of dark bands in the structure of the "H" macronucleus of the small cellular types as well as the presence of intermediate forms between "H" and "X" in these two species...
December 2010: Parasite: Journal de la Société Française de Parasitologie
https://www.readbyqxmd.com/read/20618278/a-multidisciplinary-primary-healthcare-clinic-for-newly-arrived-humanitarian-entrants-in-regional-nsw-model-of-service-delivery-and-summary-of-preliminary-findings
#17
Gillian Gould, Kerri Viney, Michele Greenwood, John Kramer, Paul Corben
OBJECTIVE: To describe a multidisciplinary primary healthcare clinic for newly arrived humanitarian entrants in regional New South Wales and report health problems and issues encountered during the initial period of operation. METHODS: A quality assurance study of the Coffs Harbour Refugee Health Clinic (a collaboration between the Area Health Service and general practitioners) was undertaken from February to December 2006. RESULTS: Seventy-six patients received a comprehensive health assessment: 69 of these within 12 months of arrival...
June 2010: Australian and New Zealand Journal of Public Health
https://www.readbyqxmd.com/read/20407575/same-game-different-rules-gender-differences-in-political-participation
#18
Hilde Coffé, Catherine Bolzendahl
We investigate gender gaps in political participation with 2004 ISSP data for 18 advanced Western democracies (N: 20,359) using linear and logistic regression models. Controlling for socio-economic characteristics and political attitudes reveals that women are more likely than men to have voted and engaged in 'private' activism, while men are more likely to have engaged in direct contact, collective types of actions and be (more active) members of political parties. Our analysis indicates that demographic and attitudinal characteristics influence participation differently among men and among women, as well as across types of participation...
March 2010: Sex Roles
https://www.readbyqxmd.com/read/20390027/citizenship-norms-in-eastern-europe
#19
Hilde Coffé, Tanja van der Lippe
Research on Eastern Europe stresses the weakness of its civil society and the lack of political and social involvement, neglecting the question: What do people themselves think it means to be a good citizen? This study looks at citizens' definitions of good citizenship in Poland, Slovenia, the Czech Republic and Hungary, using 2002 European Social Survey data. We investigate mean levels of civic mindedness in these countries and perform regression analyses to investigate whether factors traditionally associated with civic and political participation are also correlated with citizenship norms across Eastern Europe...
May 2010: Social Indicators Research
https://www.readbyqxmd.com/read/20169800/drugs-discrimination-and-disability
#20
Frances Gibson
Whether addiction to prohibited drugs should be classified as a disability for the purposes of disability discrimination is a controversial question in Australia. The leading Australian case of Marsden v Human Rights Equal Opportunity Commission & Coffs Harbour & District Ex-Servicemen & Women's Memorial Club Ltd (HREOC, No H98/51, 30 August 1999); [2000] FCA 1619 concerned a disability discrimination complaint brought by Mr Marsden as a result of his treatment by the club. The case was brought as a public interest test case by the New South Wales Legal Aid Commission...
December 2009: Journal of Law and Medicine
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