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https://www.readbyqxmd.com/read/29333031/a-case-of-multifocal-eosinophilic-granuloma-involving-spine-and-pelvis-in-a-young-adult-a-radiopathological-correlation
#1
Santosh Rai, H B Sridevi, Radha R Pai, Pulastya Sanyal
We present a case of multiple osteolytic lesions in a 28-year-old adult who presented with headache, back pain, and hip pain of 6 months. There was no history of localized swelling or rise of temperature, no history of weight loss or evening rise of temperature. On examination, there were no focal neurological deficits. Routine laboratory investigations, including total leukocyte counts, differential leukocyte counts, hemoglobin, and platelet counts, were within normal limits. There was a borderline elevation of erythrocyte sedimentation rate...
October 2017: Indian Journal of Medical and Paediatric Oncology
https://www.readbyqxmd.com/read/29332238/normal-variation-in-sagittal-spinal-alignment-parameters-in-adult-patients-an-eos-study-using-serial-imaging
#2
Hwee Weng Dennis Hey, Kian Loong Melvin Tan, Vikaesh Moorthy, Eugene Tze-Chun Lau, Leok-Lim Lau, Gabriel Liu, Hee-Kit Wong
PURPOSE: To describe normal variations in sagittal spinal radiographic parameters over an interval period and establish physiological norms and guidelines for which these images should be interpreted. METHODS: Data were prospectively collected from a continuous series of adult patients with first-episode mild low back pain presenting to a single institution. The sagittal parameters of two serial radiographic images taken 6-months apart were obtained with the EOS® slot scanner...
January 13, 2018: European Spine Journal
https://www.readbyqxmd.com/read/29332029/biomechanical-effects-of-uss-fixation-with-different-screw-insertion-depths-on-the-vertebrae-stiffness-and-screw-stress-for-the-treatment-of-the-l1-fracture
#3
Jifeng Liu, Sheng Yang, Jianmin Lu, Dapeng Fu, Xipeng Liu, Depeng Shang
OBJECTIVE: To evaluate the biomechanical effects of internal fixation with different screw insertion depths on vertebrae stiffness and screw stress for L1 fracture. METHODS: The established L1 fracture was fixed with 10 different depths of screw insertion: 10-100% screw-path length (SPL). Loading on the T12 endplate was simulated. RESULTS: Screws inserted to 60-100% depths has a higher axial displacement of screw against injured vertebrae and maximum stress of screws compared to those of screws inserted to 30-50% depths and 10-20% (P< 0...
December 29, 2017: Journal of Back and Musculoskeletal Rehabilitation
https://www.readbyqxmd.com/read/29327178/clinical-impact-and-risk-factors-for-skeletal-muscle-loss-after-complete-resection-of-early-non-small-cell-lung-cancer
#4
Shinkichi Takamori, Gouji Toyokawa, Tatsuro Okamoto, Mototsugu Shimokawa, Fumihiko Kinoshita, Yuka Kozuma, Taichi Matsubara, Naoki Haratake, Takaki Akamine, Kazuki Takada, Masakazu Katsura, Fumihiko Hirai, Fumihiro Shoji, Tetsuzo Tagawa, Yoshinao Oda, Hiroshi Honda, Yoshihiko Maehara
BACKGROUND: A relationship between sarcopenia diagnosed by skeletal muscle area (SMA) and poor prognosis in cancer patients has recently been reported. This study aimed to clarify the clinical significance of postoperatively decreased SMA in patients with early non-small cell lung cancer (NSCLC). METHODS: This study selected 101 patients with pathologic stage 1 NSCLC who had undergone pre- and postoperative (~ 1 year) computed tomography scans and lobectomy between 2005 and 2010 at Kyushu University Hospital...
January 11, 2018: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/29325333/-biomechanical-effects-on-adjacent-segments-of-different-growing-rod-fixation-in-early-onset-scoliosis
#5
Y Hai, A X Pan, Y G Li, L Zang, S Yuan
Objective: To analyse the biomechanical effects on adjacent segments of different growing-rod (GR) fixation in early onset scoliosis through a finite element analysis method. Methods: A severe early-onset scoliosis patient was selected and the pre-operation and post-GR-operation (Upper instrumented levels: T(4), T(5). Lower instrumented levels: L(3), L(4)) whole spine 3-dimentional CT scan data were collected to build the finite models. Based on the different models, biomechanical differences on adjacent segments were analysed...
December 26, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/29324925/bone-scintigraphy-can-diagnose-osteoporotic-vertebral-compression-fractures-better-than-conventional-radiography
#6
Sanja Dugonjić, Boris Ajdinović, Milan Ćirković, Gorica Ristić
OBJECTIVE: Most difficult and very frequent complications of osteoporosis are vertebral compression fractures (VCF). Bone scintigraphy with 99mTc-phosphonates enables early detection of vertebral compression fractures in the first 72 hours of occuring. Typical scintigraphic findings is markedly increased radiotracer uptake in the linear pattern, throughout collapsed vertebral body. Bone scintigraphy is usefull in follow-up of vertebral fractures healing, showing reduction of radiotracer uptake in fractured vertebrae...
September 2017: Hellenic Journal of Nuclear Medicine
https://www.readbyqxmd.com/read/29324892/genetic-factors-have-a-major-effect-on-growth-number-of-vertebrae-and-otolith-shape-in-atlantic-herring-clupea-harengus
#7
Florian Berg, Oda W Almeland, Julie Skadal, Aril Slotte, Leif Andersson, Arild Folkvord
Atlantic herring, Clupea harengus, have complex population structures. Mixing of populations is known, but the extent of connectivity is still unclear. Phenotypic plasticity results in divergent phenotypes in response to environmental factors. A marked salinity gradient occurs from Atlantic Ocean (salinity 35) into the Baltic Sea (salinity range 2-12). Herring from both habitats display phenotypic and genetic variability. To explore how genetic factors and salinity influence phenotypic traits like growth, number of vertebrae and otolith shape an experimental population consisting of Atlantic purebreds and Atlantic/Baltic F1 hybrids were incubated and co-reared at two different salinities, 16 and 35, for three years...
2018: PloS One
https://www.readbyqxmd.com/read/29324879/localized-zinc-distribution-in-shark-vertebrae-suggests-differential-deposition-during-ontogeny-and-across-vertebral-structures
#8
Vincent Raoult, Nicholas Howell, David Zahra, Victor M Peddemors, Daryl L Howard, Martin D de Jonge, Benjamin L Buchan, Jane E Williamson
The development of shark vertebrae and the possible drivers of inter- and intra-specific differences in vertebral structure are poorly understood. Shark vertebrae are used to examine life-history traits related to trophic ecology, movement patterns, and the management of fisheries; a better understanding of their development would be beneficial to many fields of research that rely on these calcified structures. This study used Scanning X-ray Fluorescence Microscopy to observe zinc distribution within vertebrae of ten shark species from five different orders...
2018: PloS One
https://www.readbyqxmd.com/read/29323631/endovascular-treatment-with-tirofiban-during-the-acute-stage-of-cervical-spinal-cord-infarction-due-to-vertebral-artery-dissection
#9
Yuanling Wu, Wenxian Li, Xiaomei Xie, Zhen Jing, Weibiao Lu, Li'an Huang
CONTEXT: Cervical spinal cord infarction is a rare and severe complication of vertebral artery dissection (VAD). We report a case of VAD in an acute stage followed by cervical spinal cord infarction that was treated using direct endovascular tirofiban infusion via digital subtraction angiography (DSA) monitoring. FINDINGS: A 48-year-old man presented with vertigo, neck pain, numbness and weakness in four limbs with subsequent cardiac and respiratory arrest. Neurological examination revealed hypoesthesia below the neck with grade one myodynamia on the right side of the limbs and zero on the left side...
January 11, 2018: Journal of Spinal Cord Medicine
https://www.readbyqxmd.com/read/29323153/skeletal-characterization-of-the-fgfr3-mouse-model-of-achondroplasia-using-micro-ct-and-mri-volumetric-imaging
#10
Mohammed Salman Shazeeb, Megan K Cox, Anurag Gupta, Wen Tang, Kuldeep Singh, Cynthia T Pryce, Robert Fogle, Ying Mu, William D Weber, Dinesh S Bangari, Xiaoyou Ying, Yves Sabbagh
Achondroplasia, the most common form of dwarfism, affects more than a quarter million people worldwide and remains an unmet medical need. Achondroplasia is caused by mutations in the fibroblast growth factor receptor 3 (FGFR3) gene which results in over-activation of the receptor, interfering with normal skeletal development leading to disproportional short stature. Multiple mouse models have been generated to study achondroplasia. The characterization of these preclinical models has been primarily done with 2D measurements...
January 11, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29322984/a-device-for-three-dimensional-quantitative-assessment-and-alignment-of-c1-2-vertebrae-during-posterior-distraction-and-fusion-technique-for-atlantoaxial-dislocation-and-or-basilar-invagination
#11
P B Karthik, Jayesh Sardhara, Nachiketa Tiwari, Sanjay Behari
The most common type of congenital C1-2 dislocation is a combined type in which atlanto-axial dislocation (AAD) and basilar invagination (BI) are often associated with a rotational dislocation and coronal tilt. An optimal surgical treatment involves reduction of AAD and BI with simultaneous correction of the rotation and coronal tilt to achieve an optimal cervical canal decompression, sagittal and coronal realignment and bony fusion. The most acceptable technique to facilitate this correction is the C1-C2 distraction technique, which is accomplished by the manual joint manipulation...
January 2018: Neurology India
https://www.readbyqxmd.com/read/29322910/flexible-memory-alloy-instrumentation-for-unilateral-transpedicular-kyphoplasty-and-guided-cement-augmentation-of-the-thoracic-spine
#12
G A Vastardis, A G Hadjipavlou, A E Marjan, M A Stojanovic, B Dial, K I Kazakos
The purpose of this novel study was to investigate the feasibility of unilateral transpedicular balloon kyphoplasty particularly of the upper thoracic vertebrae using an 11- gauge balloon and cement inserter, and to study the morphological parameters of the thoracic spine pedicles. We used four fresh frozen cadaveric thoracic spines with intact rib cages and skin for kyphoplasty from T1 to T12 vertebrae under C-arm fluoroscopy. The most limiting width of the pedicles 2.46+/-0.32mm was in the middle levels (T5-T8)...
March 2017: Acta Orthopaedica Belgica
https://www.readbyqxmd.com/read/29322211/-within-ring-based-sacroiliac-rod-fixation-may-overcome-the-weakness-of-spinopelvic-fixation-for-unstable-pelvic-ring-injuries-technical-notes-and-clinical-outcomes
#13
Kentaro Futamura, Tomonori Baba, Atsuhiko Mogami, Akio Kanda, Osamu Obayashi, Hideaki Iwase, Kazuo Kaneko
PURPOSE: Spinopelvic fixation and triangular osteosynthesis give firm internal fixation for unstable pelvic ring injuries (UPRI), but with sacrifice of mobility of the lumbar spine. Here, we describe the procedure and outcomes of a new approach, which we refer to as "within ring"-based sacroiliac rod fixation (SIRF). METHODS: The patient was placed in a prone position and longitudinal skin incisions were made at the medial margins of the bilateral posterior superior iliac spines (PSIS)...
January 10, 2018: International Orthopaedics
https://www.readbyqxmd.com/read/29320399/on-farm-evaluation-of-a-novel-mechanical-cervical-dislocation-device-for-poultry
#14
Jessica E Martin, Victoria Sandilands, Julian Sparrey, Laurence Baker, Dorothy E F McKeegan
Urgent development of alternative on-farm killing methods for poultry is required following the number restrictions placed on the use of traditional manual cervical dislocation by European Legislation (EU 1099/2009). Alternatives must be proven to be humane and, crucially, practical in commercial settings with multiple users. We assessed the performance and reliability of a novel mechanical cervical dislocation device (NMCD) compared to the traditional manual cervical dislocation (MCD) method. NMCD was based on a novel device consisting of a thin supportive glove and two moveable metal finger inserts designed to aid the twisting motion of cervical dislocation...
January 10, 2018: Animals: An Open Access Journal From MDPI
https://www.readbyqxmd.com/read/29317698/occlusal-disharmony-induced-stress-causes-osteopenia-of-the-lumbar-vertebrae-and-long-bones-in-mice
#15
Yasuhiro Shimizu, Masud Khan, Genki Kato, Kazuhiro Aoki, Takashi Ono
Excessive exposure to glucocorticoids causes osteoporosis in children and adults. Occlusal disharmony is known to induce an increase in serum corticosteroid levels in murine models, but the influence of occlusal disharmony-induced stress on the bone mass during the growth period has not yet been clarified. The purpose of this study was to investigate whether occlusal disharmony-induced stress decreases bone mass. Five-week-old C57BL/6J male mice were used. A 0.5-mm increase in the vertical height of occlusion was used to induce occlusal disharmony for a period of 7 days...
January 9, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29316367/development-of-the-lunate-shaped-caudal-fin-in-white-shark-embryos
#16
Taketeru Tomita, Minoru Toda, Kei Miyamoto, Shin-Ichiro Oka, Keiichi Ueda, Keiichi Sato
The lunate-shaped caudal fin in lamnid sharks is a morphological specialization for their thunniform mode of locomotion, but its developmental process during gestation has been poorly investigated. Observations of 21 embryonic specimens of the white shark (Carcharodon carcharias) revealed that their caudal fin morphology drastically changes from strongly heterocercal to lunate-shaped through ontogeny. This morphological change involves 1) rapid elongation of the ventral lobe, 2) increased upward curvature of the vertebra within the caudal fin, and 3) formation of keels at both lateral sides of the caudal fin base...
January 6, 2018: Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology
https://www.readbyqxmd.com/read/29315127/tidemark-avulsions-are-a-predominant-form-of-endplate-irregularity
#17
Britta Berg-Johansen, Deeptee Jain, Ellen C Liebenberg, Aaron J Fields, Thomas M Link, Conor W O'Neill, Jeffrey C Lotz
STUDY DESIGN: Descriptive histologic and MRI study of human cadaveric spines. OBJECTIVE: To identify and characterize common endplate pathologies to form a histologic foundation for an etiology-based classification system. SUMMARY OF BACKGROUND DATA: Irregularities at the spinal disc-vertebra interface are associated with back pain and intervertebral disc herniation injuries. However, there is currently a lack of consensus regarding terminology for classification...
January 8, 2018: Spine
https://www.readbyqxmd.com/read/29315121/cervical-total-disk-arthroplasty
#18
Timothy T Roberts, Ryan J Filler, Jason W Savage, Edward C Benzel
In the United States, cervical total disk arthroplasty (TDA) is US Federal Drug Administration (FDA) approved for use in both 1 and 2-level constructions for cervical disk disease resulting in myelopathy and/or radiculopathy. TDA designs vary in form, function, material composition, and even performance in vivo. However, the therapeutic goals are the same: to remove the painful degenerative/damaged elements of the intervertebral discoligamenous joint complex, to preserve or restore the natural range of spinal motion, and to mitigate stresses on adjacent spinal segments, thereby theoretically limiting adjacent segment disease (ASDis)...
January 8, 2018: Clinical Spine Surgery
https://www.readbyqxmd.com/read/29314651/prevalence-and-predictors-of-asymptomatic-vertebral-fractures-in-inflammatory-myositis
#19
Latika Gupta, Able Lawrence, Sukesh Edavalath, Ramnath Misra
AIM: To assess the frequency and risk factors of asymptomatic vertebral fractures in inflammatory myositis. PATIENTS AND METHODS: Dorsal and lumbar spine lateral radiographs were taken for adults with inflammatory myositis and scored using Genant's semi-quantitative technique. Demographic data, weight, height, postmenopausal status, duration of corticosteroid use, drug intake, co-morbidities and past history of fractures were recorded. Bone mineral density (BMD) was assessed using dual-energy X-ray absorptiometry (DEXA)...
January 5, 2018: International Journal of Rheumatic Diseases
https://www.readbyqxmd.com/read/29314261/future-osteoporotic-fracture-risk-related-to-lumbar-vertebral-trabecular-attenuation-measured-at-routine-body-ct
#20
Scott J Lee, Peter M Graffy, Ryan D Zea, Timothy J Ziemlewicz, Perry J Pickhardt
We sought to determine if vertebral trabecular attenuation values measured on routine body CT scans obtained for a variety of unrelated indications can predict future osteoporotic fractures at multiple skeletal sites. For this HIPAA-compliant and IRB-approved retrospective cohort study, trabecular attenuation of the first lumbar vertebra was measured in 1966 consecutive older adults who underwent chest and/or abdominal CT at a single institution over the course of one year. New pathologic fragility fractures that occurred after a patient's CT study date were identified through an electronic health record database query using ICD-9 codes for vertebral, hip, and extremity fractures...
January 3, 2018: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
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