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https://www.readbyqxmd.com/read/28724358/quality-of-care-and-quality-of-life-of-people-with-dementia-living-at-green-care-farms-a-cross-sectional-study
#1
Bram de Boer, Jan P H Hamers, Sandra M G Zwakhalen, Frans E S Tan, Hilde Verbeek
BACKGROUND: Many countries are introducing smaller, more home-like care facilities that represent a radically new approach to nursing home care for people with dementia. The green care farm is a new type of nursing home developed in the Netherlands. The goal of this study was to compare quality of care, quality of life and related outcomes in green care farms, regular small-scale living facilities and traditional nursing homes for people with dementia. METHODS: A cross-sectional design was used...
July 19, 2017: BMC Geriatrics
https://www.readbyqxmd.com/read/28724302/efficacy-and-safety-of-vedolizumab-as-a-treatment-option-for-moderate-to-severe-refractory-ulcerative-colitis-in-two-patients-after-liver-transplant-due-to-primary-sclerosing-cholangitis
#2
Raúl Vicente Olmedo Martín, Víctor Amo Trillo, Rocío González Grande, Miguel Jiménez Pérez
Vedolizumab is a humanized IgG1 monoclonal antibody that selectively blocks the lymphocyte integrin α4β7 and prevents its interaction with endothelial adhesion molecules and subsequent transmigration to the gastrointestinal tract. The drug was approved in 2014 for the induction and maintenance treatment of ulcerative colitis and moderate to severe Crohn's disease that is refractory or intolerant to conventional treatment with corticoids and immunosuppressants and/or anti-TNFα drugs. However, inflammatory bowel disease has a variable behavior following liver transplant...
July 14, 2017: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/28704991/a-strange-perianal-ulcer
#3
Gaia Moretta, Clara DE Simone, Ilaria Esposito, Alessandro DI Stefani, Ketty Peris
No abstract text is available yet for this article.
July 11, 2017: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
https://www.readbyqxmd.com/read/28702316/sporotrichosis-in-a-liver-transplant-patient-a-case-report-and-literature-review
#4
Renato Ferreira da Silva, Miguel Bonfitto, Francisco Inaldo Mendes da Silva Junior, Margarete Teresa Gottardo de Ameida, Rita de Cma da Silva
The liver transplant patient was admitted to the hospital with hyperemic, granulomatous, ulcerated lesion in the anterior compartment of the right lower limb with report of local trauma. The agent Sporothrix schenckii was isolated from biopsy of the lesion and lymph nodes of the right lower limb. In this case, the treatment was difficult because the patient has severe pulmonary hypertension and took the following drugs: warfarin, sildenafil, and tacrolimus. These medicines interact with the antifungal, which made it difficult...
September 2017: Medical Mycology Case Reports
https://www.readbyqxmd.com/read/28700534/clinical-predictors-of-future-nonadherence-in-inflammatory-bowel-disease
#5
Mirjam Severs, Marie-Josée J Mangen, Herma H Fidder, Mirthe E van der Valk, Mike van der Have, Ad A van Bodegraven, Cees H M Clemens, Gerard Dijkstra, Jeroen M Jansen, Dirk J de Jong, Nofel Mahmmod, Paul C van de Meeberg, Andrea E van der Meulen-de Jong, Marieke Pierik, Cyriel Y Ponsioen, Marielle J L Romberg-Camps, Peter D Siersema, Bindia Jharap, Janneke C van der Woude, Nicolaas P A Zuithoff, Bas Oldenburg
BACKGROUND: Nonadherence to medical therapy is frequently encountered in patients with inflammatory bowel disease (IBD). We aimed to identify predictors for future (non)adherence in IBD. METHODS: We conducted a multicenter prospective cohort study with adult patients with Crohn's disease (CD) and ulcerative colitis (UC). Data were collected by means of 3-monthly questionnaires on the course of disease and healthcare utilization. Medication adherence was assessed using a visual analogue scale, ranging from 0% to 100%...
July 11, 2017: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/28700056/injuries-caused-by-freshwater-stingrays-in-the-tapaj%C3%A3-s-river-basin-a-clinical-and-sociodemographic-study
#6
Paulo Afonso Martins Abati, Pasesa Pascuala Quispe Torrez, Francisco Oscar de Siqueira França, Fabio Lambertini Tozzi, Flávio Mileo Bacelar Guerreiro, Suellen Aline Torres Dos Santos, Sheyla Mara Silva de Oliveira, Vidal Haddad
INTRODUCTION: Freshwater stingray envenomations are an important cause of morbidity in riverine populations living in various regions of Brazil. The sequelae include temporary or permanent disability. This study aimed to identify sociodemographic, clinical, and therapeutic aspects related to stingray injuries in such populations. METHODS: This cross-sectional study was conducted in the Extractive Reserve of Tapajos-Arapiuns, located in the municipalities of Santarém and Aveiro (Pará State)...
May 2017: Revista da Sociedade Brasileira de Medicina Tropical
https://www.readbyqxmd.com/read/28698211/extra-rectal-lymphogranuloma-venereum-in-france-a-clinical-and-molecular-study
#7
Arnaud Desclaux, Arabella Touati, Didier Neau, Cécile Laurier-Nadalié, Cécile Bébéar, Bertille de Barbeyrac, Charles Cazanave
OBJECTIVES: To describe a series of extrarectal lymphogranuloma venereum (LGV) cases diagnosed in France. METHODS: Consecutive LGV cases confirmed at the French Reference Centre for chlamydiae with an extrarectal sample from January 2010 to December 2015 were included. The first part of the study consisted of a retrospective case note review and analysis. In a second part, the complete ompA gene sequence of our samples was determined. RESULTS: There were 56 cases overall: 50 cases of genital LGV and six cases of pharyngeal LGV...
July 11, 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/28694758/safety-assessment-and-antioxidant-activity-of-lantana-montevidensis-leaves-contribution-to-its-phytochemical-and-pharmacological-activity
#8
Luiz Marivando Barros, Antonia Eliene Duarte, Emily Pansera Waczuk, Katiane Roversi, Francisco Assis Bezerra da Cunha, Mirian Rolon, Cathia Coronel, Maria Celeste Vega Gomez, Irwin Rose Alencar de Menezes, José Galberto Martins da Costa, Aline Augusti Boligon, Waseem Hassan, Diogo Onofre Souza, João Batista Teixeira da Rocha, Jean Paul Kamdem
Lantana camara, the widely studied species, and L. montevidensis, the less studied species of the genus Lantana are both used in traditional medicine for the same purpose (anti-asthma, anti-ulcer, anti-tumor, etc). However, little is known about the toxicity of L. montevidensis and there is limited information on its chemical constituents. Here, we investigated for the first time the genotoxicity and cytotoxicity of the ethanolic (EtOH) and aqueous extracts from the leaves of Lantana montevidensis in human leukocytes, as well as their possible interaction with human erythrocyte membranes in vitro...
2017: EXCLI journal
https://www.readbyqxmd.com/read/28694133/ectopic-pregnancy-in-women-with-inflammatory-bowel-disease-a-22-year-nationwide-cohort-study
#9
Punyanganie S de Silva, Helene H Hansen, Sonja Wehberg, Sonia Friedman, Bente M Nørgård
BACKGROUND & AIMS: Data on early adverse pregnancy outcomes in inflammatory bowel disease (IBD) such as ectopic pregnancy (EP) remain limited. We assessed the risk of EP in pregnancies of Danish women with IBD compared to all other Danish women over a 22-year period. In addition, we examined the disease-specific risk of EP in pregnancies of women with ulcerative colitis (UC) or Crohn's disease (CD) who underwent IBD-related surgical procedures. METHODS: We obtained nationwide data in all women of child-bearing age who had at least one pregnancy resulting in either an EP, hydatiform mole, induced abortion, miscarriage, or live birth from January 1994 through 2015...
July 7, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28691939/autoantibodies-against-glycoprotein-2-isoforms-in-pediatric-patients-with-inflammatory-bowel-disease
#10
Nadja Röber, Lydia Noß, Alexander Goihl, Dirk Reinhold, Josefine Jahn, Jan de Laffolie, Wolf Johannes, Gunter M Flemming, Dirk Roggenbuck, Karsten Conrad, Martin W Laass
BACKGROUND: Anti-Glycoprotein 2 (GP2) antibodies are associated with a more complicated course of Crohn's disease (CD) in adults. Four different GP2 isoforms with different length and antibody-binding sites have been identified so far but not been explored in serological studies. We aimed to investigate the diagnostic utility of autoantibodies against all 4 isoforms of GP2 in an exclusively pediatric population for the first time. METHODS: We included 278 children and adolescents with inflammatory bowel disease: 164 with CD, 114 with ulcerative colitis, 83 disease controls (acute gastrointestinal infection, nonspecific gastrointestinal functional disorders), and 219 healthy controls...
July 6, 2017: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/28691045/pharyngocutaneous-fistula-as-an-alternative-access-route-for-inserting-a-percutaneous-endoscopic-gastrostomy-tube-in-head-and-neck-cancer-patients
#11
Louise Deluiz Verdolin Di Palma, Gustavo Francisco de Souza E Mello, Cindy Lis Granados, Ricardo Dardengo Glória, Caroline Sauter Dalbem, Rolantre Lopes da Cruz, Ana Carolina Maron Ayres, Renata Sofia Camara Lisboa, Alexandre Dias Pelosi, Maria Aparecida Ferreira, Gilberto Reynaldo Mansur, Simone Guaraldi da Silva, Theresa Christina Damian Ribeiro, Fernando Luiz Dias
BACKGROUND AND STUDY AIMS:  Performing a percutaneous endoscopic gastrostomy (PEG) in head and neck cancer (HNC) patients can be challenging because of the presence of trismus, pharyngeal obstruction by tumor, and pharyngoesophageal strictures or fistula. Pharyngocutaneous fistula (PCF) is a major postoperative concern in patients submitted to total laryngectomy (TL). In the medical literature to date, the cervical fistula has been used as an access to PEG in only four reports. The aim of this study was to evaluate the safety of cervical fistula for insertion of a PEG tube...
July 2017: Endoscopy International Open
https://www.readbyqxmd.com/read/28689150/association-of-urinary-phenolic-compounds-inflammatory-bowel-disease-and-chronic-diarrheal-symptoms-evidence-from-the-national-health-and-nutrition-examination-survey
#12
Punyanganie S de Silva, Xuan Yang, Joshua R Korzenik, Rose H Goldman, Kristopher L Arheart, Alberto J Caban-Martinez
Endocrine disruptors such as phenolic compounds and parabens may be involved in chronic non-infective disease. While products incorporating these compounds are extensively utilized in consumer and personal products, little is known about their effect on bowel health. Inflammatory bowel disease (IBD) - consisting of the diseases ulcerative colitis and Crohn's disease - and irritable bowel syndrome are common chronic non-infectious diarrheal diseases. Despite limited knowledge on the etiology of IBD, these diseases have increased prevalence in industrialized countries and cause significant impairment to quality of life...
July 6, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28685382/safety-and-efficacy-of-transarterial-radioembolisation-in-patients-with-intermediate-or-advanced-stage-hepatocellular-carcinoma-refractory-to-chemoembolisation
#13
Elisabeth G Klompenhouwer, Raphaëla C Dresen, Chris Verslype, Annouschka Laenen, Gert De Hertogh, Christophe M Deroose, Lawrence Bonne, Vincent Vandevaveye, Geert Maleux
INTRODUCTION: Transarterial chemoembolisation (TACE) is the most widely used locoregional treatment for patients with an unresectable hepatocellular carcinoma (HCC). Transarterial radioembolisation (TARE) with yttrium-90 containing microspheres is an emerging interventional treatment that could be complementary or an alternative to TACE. AIM: To evaluate the safety and efficacy of TARE in patients with HCC who are refractory to TACE with drug-eluting beads (DEB-TACE)...
July 6, 2017: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/28679280/assessing-medication-adherence-in-inflammatory-bowel-diseases-a-comparison-between-a-self-administered-scale-and-a-pharmacy-refill-index
#14
María Luisa de Castro, Luciano Sanromán, Alicia Martín, Montserrat Figueira, Noemi Martínez, Vicent Hernández, Victor Del Campo, Juan R Pineda, Jesús Martínez-Cadilla, Santos Pereira, José Ignacio Rodríguez Prada
BACKGROUND: Medication non-adherence in inflammatory bowel disease (IBD) has a negative impact on disease outcome. Different tools have been proposed to assess non-adherence. We aimed to compare a self-administered scale and a pharmacy refill index as a reliable measure of medication adherence and to determine what factors are related to adherence. METHODS: Consecutive non-active IBD outpatients were asked to fill in the self-reported Morisky Medication Adherence Scale (MMAS-8) and the Beliefs about Medication Questionnaire (BMQ)...
July 6, 2017: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/28679196/kaposi-s-sarcoma-an-unusual-penile-lesion-in-a-hiv-negative-patient
#15
Aldo Franco De Rose, Matteo Justich, Guglielmo Mantica, Nicolò Testino, Carlo Terrone
Kaposi's sarcoma (KS) of the penis is a very rare lesion and it is usually observed in HIV-infected patients. We introduce a case of KS of the penis in a 75 years old HIV negative patient with a peripheral T-cell lymphoma. He came to our attention with a painful ulcerated red lesion on the glans that stretched from the urethral meatus to the coronal skin. This lesion was found to be a KS balanopreputial in the classical variant. Penile KS must be included in the differential diagnosis of genital diseases especially when the clinical features of the lesion are aspecific and diagnosis can be made histologically by performing a biopsy...
June 30, 2017: Archivio Italiano di Urologia, Andrologia
https://www.readbyqxmd.com/read/28678976/probiotic-therapy-reduces-inflammation-and-improves-intestinal-morphology-in-rats-with-induced-oral-mucositis
#16
Dayana Gerhard, Frederico José da Silva Simão de Sousa, Rodrigo Antonio Carvalho Andraus, Paulo Eduardo Pardo, Gisele Alborguetti Nai, Hermann Bremer Neto, Michel Reis Messora, Luciana Prado Maia
The aim of the present study was to evaluate the effect of systemic administration of probiotics (PROB) on the progression of experimentally induced oral and intestinal mucositis in rats immunosuppressed by chemotherapy (5-fluorouracil: 5-FU). Twenty-four rats were divided into the following groups (n=6): GC (control), GPROB, G5FU and G5-FU/PROB. Groups GPROB and G5-FU/PROB received 1 g of probiotic incorporated into each 100 g of feed (Bacillus subtilis, Bifidobacterium bifidum, Enterococcus faecium and Lactobacilllus acidophilus), beginning 30 days before oral mucositis induction...
July 3, 2017: Brazilian Oral Research
https://www.readbyqxmd.com/read/28675163/long-term-efficacy-and-safety-of-cyclosporine-in-a-cohort-of-steroid-refractory-acute-severe-ulcerative-colitis-patients-from-the-eneida-registry-1989-2013-a-nationwide-multicenter-study
#17
I Ordás, E Domènech, M Mañosa, V García-Sánchez, E Iglesias-Flores, M Peñalva, A Cañas-Ventura, O Merino, F Fernández-Bañares, F Gomollón, M Vera, A Gutiérrez, E Garcia-Planella, M Chaparro, M Aguas, E Gento, F Muñoz, M Aguirresarobe, C Muñoz, L Fernández, X Calvet, C E Jiménez, M A Montoro, A Mir, M L De Castro, M F García-Sepulcre, F Bermejo, J Panés, M Esteve
OBJECTIVES: To determine the efficacy and safety of cyclosporine (CyA) in a large national registry-based population of patients with steroid-refractory (SR) acute severe ulcerative colitis (ASUC) and to establish predictors of efficacy and adverse events. METHODS: Multicenter study of SR-ASUC treated with CyA, based on data from the ENEIDA registry. SR-ASUC patients treated with infliximab (IFX) or sequential rescue therapy (CyA-IFX or IFX-CyA) were used as comparators...
July 4, 2017: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/28674950/confocal-laser-endomicroscopy-in-ulcerative-colitis-beyond-endoscopic-assessment-of-disease-activity
#18
F Maione, M C Giglio, G Luglio, A Rispo, M D'Armiento, B Manzo, G Cassese, P Schettino, N Gennarelli, S Siciliano, F P D'Armiento, G D De Palma
BACKGROUND: The aim of this study was to investigate the role of confocal laser endomicroscopy (CLE) in the assessment of disease activity in ulcerative colitis (UC). METHODS: Consecutive patients with UC referred to our inflammatory bowel disease unit for colonoscopy were enrolled. Patients without UC were used as controls. UC activity was evaluated by white light endoscopy and classified according to the Mayo Ulcerative Colitis Endoscopic Score of Severity. Endoscopic biopsies were also taken for histological assessment of disease activity and then assessed with CLE...
July 3, 2017: Techniques in Coloproctology
https://www.readbyqxmd.com/read/28671873/clinical-outcomes-of-golimumab-as-first-second-or-third-anti-tnf-agent-in-patients-with-moderate-to-severe-ulcerative-colitis
#19
Carlos Taxonera, Cristina Rodríguez, Federico Bertoletti, Luís Menchén, Julia Arribas, Mónica Sierra, Lara Arias, Pilar Martínez-Montiel, Alba Juan, Eva Iglesias, Alicia Algaba, Noemí Manceñido, Montserrat Rivero, Manuel Barreiro-de Acosta, Pilar López-Serrano, Federico Argüelles-Arias, Ana Gutierrez, David Busquets, Javier P Gisbert, David Olivares, Marta Calvo, Cristina Alba
BACKGROUND: Golimumab efficacy data in ulcerative colitis (UC) are limited to anti-tumor necrosis factor α (TNF)-naive patients. The aim of this study was to assess the short-term and long-term efficacy of golimumab used as first, second, or third anti-TNF in UC in a real-life clinical setting. METHODS: This retrospective multicenter cohort study included patients with moderate-to-severe UC treated with golimumab. The primary efficacy endpoints were short-term partial Mayo score response, long-term golimumab failure-free survival, and colectomy-free survival...
August 2017: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/28670843/poorly-differentiated-vaginal-adenocarcinoma-with-aggressive-behavior-pap-smear-findings
#20
José Eleutério, Francisca Margalene Medeiros de Freitas, Denise Nunes Oliveira, David Freitas Moreira, Mirley Sângela Pessoa
Vaginal carcinoma is a rare condition. In this report, we describe a case of a poorly differentiated aggressive adenocarcinoma in a woman with a three month history of vaginal bleeding and a negative Pap smear done six months prior to her consultation. Specular examination showed a normal cervix, but there was a bleeding ulcer (2 cm in diameter) in the upper third of the vagina. Cytology revealed poorly differentiated atypical cells, and the biopsy established a diagnosis of vaginal adenocarcinoma with little differentiation...
July 3, 2017: Diagnostic Cytopathology
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