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https://www.readbyqxmd.com/read/28209098/the-predictive-value-of-negative-capsule-endoscopy-for-the-indication-of-obscure-gastrointestinal-bleeding-no-reassurance-in-the-long-term
#1
C Van de Bruaene, P Hindryckx, C Snauwaert, D Dooremont, B Vanduyfhuys, L Vandenabeele, M De Vos, D De Looze
BACKGROUND: Capsule Endoscopy (CE) has become the first-line tool to identify an underlying etiology for Obscure Gastrointestinal Bleeding (OGIB) in the small bowel (SB). This study aims to investigate the long-term outcome of patients with a negative CE. METHODS: Retrospective review of standardized application forms of all patients who underwent CE for OGIB at the Ghent University Hospital between 2002 and 2013. Follow-up data on patients with a negative CE result (n=263) were collected by contacting the referring physician...
September 2016: Acta Gastro-enterologica Belgica
https://www.readbyqxmd.com/read/28203157/azathioprine-hypersensitivity-syndrome-two-cases-of-febrile-neutrophilic-dermatosis-induced-by-azathioprine
#2
Majed Aleissa, Perrine Nicol, Marion Godeau, Emilie Tournier, Frederic de Bellissen, Marie-Angèle Robic, Cristina Bulai Livideanu, Juliette Mazereeuw-Hautier, Carle Paul
BACKGROUND: Azathioprine is an immunosuppressive agent used in the treatment of immune-mediated diseases. Azathioprine hypersensitivity syndrome is a rare adverse reaction occurring a few days to weeks after the administration of azathioprine. CASE 1: A 36-year-old male with ulcerative colitis presented with erythematous plaques, pustules and erosions on the lower back, buttocks and thighs associated with high fever (39°C) 2 weeks after the initiation of azathioprine 100 mg/day...
January 2017: Case Reports in Dermatology
https://www.readbyqxmd.com/read/28198943/clinic-validation-protocol-for-venous-ulcers-in-high-complexity
#3
Daniele Vieira Dantas, Gilson de Vasconcelos Torres, Marina de Góes Salvetti, Isabelle Katherinne Fernandes Costa, Rodrigo Assis Neves Dantas, Rhayssa de Oliveira E Araújo
Objective: To perform clinical validation of a clinical protocol for treatment of individuals with venous ulcers in highly complex health services. Method: Methodological quantitative study conducted by four specialist nurses who evaluated 32 patients with venous ulcers, at the Onofre Lopes University Hospital, in Natal/Rio Grande do Norte. Data was collected between July and December/2013 and analysis was carried out using Kappa test (K), considering K ≥ 0.61...
February 9, 2017: Revista Gaúcha de Enfermagem
https://www.readbyqxmd.com/read/28198913/body-composition-in-patients-with-crohn-s-disease-and-ulcerative-colitis
#4
Ivi Ribeiro Back, Sonia Silva Marcon, Natalia Moreno Gaino, Daniela Salate Biagioni Vulcano, Mariana de Souza Dorna, Ligia Yukie Sassaki
BACKGROUND: The nutritional status of individuals with inflammatory bowel diseases is directly related to the severity of the disease and is associated with poor prognosis and the deterioration of immune competence. OBJECTIVE: To assess the nutritional status and the body composition of outpatients with inflammatory bowel diseases. METHODS: A cross-sectional study was conducted with clinical and nutritional assessment of patients with Crohn's disease and ulcerative colitis...
February 13, 2017: Arquivos de Gastroenterologia
https://www.readbyqxmd.com/read/28198912/inflammatory-bowel-disease-outpatient-treatment-profile
#5
Rachael Miranda Dos Santos, Ana Teresa Pugas Carvalho, Kelly Dos Santos Silva, Selma Petra Chaves Sá, Aparecida Helena Dos Santos, Millene Ramos Sandinha
BACKGROUND: Crohn's disease and ulcerative colitis are the two major forms of inflammatory bowel disease. The incidence and prevalence of both conditions have increased and are progressively increasing. These diseases are frequently recurrent and clinically highly severe. In Brazil, the lack of epidemiological data related to such diseases has left these patients in a vulnerable state and contributed to increased morbidity. OBJECTIVE: To describe the profiles of patients with inflammatory bowel disease treated in an outpatient service in Brazil...
February 13, 2017: Arquivos de Gastroenterologia
https://www.readbyqxmd.com/read/28194903/vitamin-k-antagonist-therapy-is-a-risk-factor-for-ulcer-development-and-death-among-dialyzed-patients
#6
Andreana De Mauri, Massimo Torreggiani, Marco Brambilla, Doriana Chiarinotti
Peripheral artery disease is a common complication among dialyzed patients. Since Vitamin K antagonists promote metastatic calcifications and these are the main determinants of vascular damage, we investigated their role in the development of lower limb ulcers in dialyzed patients. We retrospectively enrolled 316 dialyzed patients, aged 68 ± 15 years, 65% male, 32% diabetic, 43% with ischemic heart disease and followed them for 36 ± 25 months. 60 patients assumed Vitamin K antagonists: they were older, with a higher prevalence of heart disease, at greater risk of death and they developed more ulcers and underwent more lower limb amputations compared to the rest of our cohort...
February 14, 2017: Therapeutic Apheresis and Dialysis
https://www.readbyqxmd.com/read/28194393/resection-osteotomy-for-calcaneus-flattening-after-micro-surgical-flap-technical-note
#7
Mário Yoshihide Kuwae, Edegmar Nunes Costa, Ricardo Pereira da Silva, Alexandre Daher Albieri, Frederico Barra de Moraes
An open fracture of the calcaneus with loss of substance is a challenging injury and requires specialized care, involves high costs, and demands attention despite its lower incidence. The main complications are osteomyelitis, pressure ulcers, and fistulas, as well as pain conditions in the lateral, medial, and plantar regions. This is due to the wide loss of tissue and the change in anatomical conformation of the calcaneus in some cases. However, in cases of flattening of the calcaneus bone, these complications may be prevented or treated successfully...
January 2017: Revista Brasileira de Ortopedia
https://www.readbyqxmd.com/read/28194218/brazilian-amazon-traditional-medicine-and-the-treatment-of-difficult-to-heal-leishmaniasis-wounds-with-copaifera
#8
REVIEW
Kelly Cristina Oliveira de Albuquerque, Andreza do Socorro Silva da Veiga, João Victor da Silva E Silva, Heliton Patrick Cordovil Brigido, Erica Patrícia Dos Reis Ferreira, Erica Vanessa Souza Costa, Andrey Moacir do Rosário Marinho, Sandro Percário, Maria Fâni Dolabela
The present study describes the use of the traditional species Copaifera for treating wounds, such as ulcers scarring and antileishmanial wounds. It also relates phytochemical studies, evaluation of the leishmanicidal activity, and toxicity. The species of Copaifera with a higher incidence in the Amazon region are Copaifera officinalis, Copaifera reticulata, Copaifera multijuga Hayne. The copaiba oil is used in the Amazon's traditional medicine, especially as anti-inflammatory ingredient, in ulcers healing, and in scarring and for leishmaniasis...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28191024/recent-trends-in-pharmacological-activity-of-alkaloids-in-animal-colitis-potential-use-for-inflammatory-bowel-disease
#9
REVIEW
Ana Cristina Alves de Almeida, Felipe Meira de-Faria, Ricardo José Dunder, Luis Paulo Bognoni Manzo, Alba Regina Monteiro Souza-Brito, Anderson Luiz-Ferreira
Inflammatory bowel disease (IBD) is a chronic and disrupted inflammation of the gastrointestinal tract. IBD have two main conditions, Crohn's disease and ulcerative colitis, and have been extensively investigated in recent years. Antibiotics derived from salicylates, steroids, immunosuppressors, and anti-TNF therapy are part of the therapeutic arsenal for IBD. However, very often patients stop responding to treatments over the time. In this context, searching for alternative agents is crucial for IBD clinical management...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28190472/gastroprotective-and-anti-secretory-mechanisms-of-2-phenylquinoline-an-alkaloid-isolated-from-galipea-longiflora
#10
Eduardo Breviglieri, Luisa Mota da Silva, Thaise Boeing, Lincon Bordignon Somensi, Benhur Judah Cury, Alberto Gimenez, Valdir Cechinel Filho, Sérgio Faloni de Andrade
BACKGROUND: We previously described the gastroprotective effect of 2-phenylquinoline (2-PQ), the main alkaloid isolated from the bark of Galipea longiflora (Rutaceae). However, despite the significant and promising results, the pharmacological mechanisms of the gastroprotection induced by 2-PQ have not been investigated. PURPOSE: To evaluate the mechanisms underlying the gastroprotective effects of 2-PQ. STUDY DESIGN: We used an in vivo mouse ulcer model and in vitro methodologies involving H⁺/K⁺-ATPase and L929 murine fibroblasts...
February 15, 2017: Phytomedicine: International Journal of Phytotherapy and Phytopharmacology
https://www.readbyqxmd.com/read/28188042/molecular-finds-of-pressure-ulcer-a-bioinformatics-approach-in-pressure-ulcer
#11
Eloa Mangabeira Santos, Lucyana Conceição Farias, Sérgio Henrique Sousa Santos, Alfredo Maurício Batista de Paula, Carla Silvana de Oliveira E Silva, André Luiz Sena Guimarães
BACKGROUND: Understanding the biological processes underlying Pressure Ulcer (PU) is an important strategy to identify new molecular targets. Bioinformatics has emerged as an important screening tool for a broad range of diseases. OBJECTIVE: This study aim of the current study is to investigate the protein-protein interaction in the PU context by bioinformatics. METHODS: We performed a search in gene databases, and bioinformatics algorithms were used to generate molecular targets for PU based in silico investigation...
January 28, 2017: Journal of Tissue Viability
https://www.readbyqxmd.com/read/28186837/methadone-and-corrected-qt-prolongation-in-pain-and-palliative-care-patients-a-case-control-study
#12
Katherine M Juba, Tina M Khadem, David J Hutchinson, Jack E Brown
BACKGROUND: Methadone (ME) is commonly used in pain and palliative care (PPC) patients with refractory pain or intolerable opioid adverse effects (AEs). A unique ME AE is its corrected QT (QTc) interval prolongation risk, but most evidence exists in methadone maintenance therapy patients. OBJECTIVE: Our goal was to identify QTc interval prolongation risk factors in PPC patients receiving ME and other medications known to prolong the QTc interval and develop a risk stratification tool...
February 10, 2017: Journal of Palliative Medicine
https://www.readbyqxmd.com/read/28177773/gastroprotective-and-antielastase-effect-of-protein-inhibitors-from-erythrina-velutina-seeds-in-an-experimental-ulcer-model
#13
Vanessa Cristina Oliveira de Lima, Richele Janaína de Araújo Machado, Norberto Monteiro, Christina da Silva Camillo, Alexandre Coelho Serquiz, Adeliana Silva de Oliveira, Fabiola Rufino, Bruna Leal Lima Maciel, Adriana Ferreira Uchôa, Elizeu Antunes Santos, Ana Heloneida de Araújo Morais
Trypsin and chymotrypsin inhibitors from Erythrina velutina seeds have been previously isolated by our group. In previous studies using a sepsis model, we demonstrated the anti-tumor and anti-inflammatory action of these compounds. This study aimed to evaluate the gastroprotective and antielastase effect of protein inhibitors from Erythrina velutina seeds in an experimental stress induced ulcer model. Two protein isolates from E. velutina seeds, with antitrypsin (PIAT) and anti-chymotrypsin (PIAQ) activities were tested...
September 12, 2016: Biochemistry and Cell Biology, Biochimie et Biologie Cellulaire
https://www.readbyqxmd.com/read/28176198/constituents-of-leaves-from-bauhinia-curvula-benth-exert-gastroprotective-activity-in-rodents-role-of-quercitrin-and-kaempferol
#14
Ana Paula Beber, Priscila de Souza, Thaise Boeing, Lincon Bordignon Somensi, Luísa Nathália Bolda Mariano, Benhur Judah Cury, Ligia Moura Burci, Cristiane Bezerra da Silva, Euclésio Simionatto, Sérgio Faloni de Andrade, Luísa Mota da Silva
The Bauhinia genus is known as "Pata-de-Vaca" and a wide variety of these species are used in Brazilian folk medicine due to their gastroprotective properties. This study aimed to investigate the antiulcer efficacy of the hydroalcoholic extract from B. curvula (HEBC) leaves, as well as its semi-purified fraction (SPFr) and the contribution of their phytochemicals constituents for this effect. For that, ethanol 60%/HCl 0.3 M- and indomethacin-induced gastric ulcer were performed in rodents. Gastric ulcerated tissues were processed for histological, histochemical and biochemical analysis...
February 7, 2017: Inflammopharmacology
https://www.readbyqxmd.com/read/28175260/p782-a-new-compatibility-test-for-donor-selection-for-faecal-microbiota-transplantation-in-ulcerative-colitis
#15
M Ponce-Alonso, S Garcia-Fernandez, L Aguilera, E Rodriguez-de-Santiago, J R Foruny, G Roy, R DelCampo, R Canton, A Lopez-Sanroman
No abstract text is available yet for this article.
February 1, 2017: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/28175057/p302-cytomegalovirus-infection-in-pediatric-acute-severe-ulcerative-colitis-a-multicenter-case-controlled-study-from-the-pediatric-ibd-porto-group-of-espghan
#16
S Cohen, C Martinez-Vinson, M Aloi, D Turner, A Assa, L de Ridder, V M Wolters, T de Meij, P Alvisi, J Bronsky, U Kopylov
No abstract text is available yet for this article.
February 1, 2017: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/28175026/p226-comparison-of-four-different-immunoassays-for-measuring-golimumab-and-anti-golimumab-antibody-concentration-in-patients-with-ulcerative-colitis
#17
S Paul, G Duru, A De Vries, J C Marini, D Aoucheta, F Cornillie, S Nancey, I Detrez, A-E Berger, A Gils, X Roblin
No abstract text is available yet for this article.
February 1, 2017: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/28172974/p382-a-panel-of-serum-markers-for-early-detection-of-endoscopic-healing-with-infliximab-in-patients-with-ulcerative-colitis
#18
M de Bruyn, R Ringold, M Ferrante, G Van Assche, G Opdenakker, A Dukler, S Vermeire
No abstract text is available yet for this article.
February 1, 2017: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/28172961/p607-post-operative-mortality-and-predictive-factors-in%C3%A2-a%C3%A2-cohort-of-severe-refractory-ulcerative-colitis-patients-from-the-eneida-registry-1989-2013-a%C3%A2-multicenter-nationwide-study
#19
I Ordas, E Domenech, M Aguas, F Fernandez-Bañares, S García, M Peñalva, C Muñoz, V García-Sánchez, J Llaό, C E Jiménez, O Merino, F Gomollόn, M Piqueras, M Vera, L Márquez, M De Castro, A Gutiérrez, J L Cabriada, N Alcaide, X Calvet, M A Montoro, L Arias, J Panés, M Esteve
No abstract text is available yet for this article.
February 1, 2017: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/28172955/p447-vedolizumab-induces-significantly-higher-endoscopic-remission-rates-at-week-16-in-ulcerative-colitis-as-compared-to-crohn-s-disease
#20
R W M Pauwels, A C De Vries, C J Van der Woude
No abstract text is available yet for this article.
February 1, 2017: Journal of Crohn's & Colitis
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