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https://www.readbyqxmd.com/read/27911489/palliative-care-interventions-in-advanced-dementia
#1
REVIEW
Edel Murphy, Katherine Froggatt, Sheelah Connolly, Eamon O'Shea, Elizabeth L Sampson, Dympna Casey, Declan Devane
BACKGROUND: Dementia is a chronic, progressive and ultimately fatal neurodegenerative disease. Advanced dementia is characterised by profound cognitive impairment, inability to communicate verbally and complete functional dependence. Usual care of people with advanced dementia is not underpinned universally by a palliative approach. Palliative care has focused traditionally on care of people with cancer but for more than a decade, there have been increased calls worldwide to extend palliative care services to include all people with life-limiting illnesses in need of specialist care, including people with dementia...
December 2, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27911487/external-inspection-of-compliance-with-standards-for-improved-healthcare-outcomes
#2
REVIEW
Gerd Flodgren, Daniela C Gonçalves-Bradley, Marie-Pascale Pomey
BACKGROUND: Inspection systems are used in healthcare to promote quality improvements (i.e. to achieve changes in organisational structures or processes, healthcare provider behaviour and patient outcomes). These systems are based on the assumption that externally promoted adherence to evidence-based standards (through inspection/assessment) will result in higher quality of healthcare. However, the benefits of external inspection in terms of organisational-, provider- and patient-level outcomes are not clear...
December 2, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27911468/radical-cystectomy-and-cutaneous-ureterostomy-in-4-dogs-with-trigonal-transitional-cell-carcinoma-description-of-technique-and-case-series
#3
Rafael Ricardo Huppes, Leandro Z Crivellenti, Andrigo Barboza De Nardi, Bruno Roque Lima, Cristiane Alves Cintra, Jorge Luiz Costa Castro, Christopher A Adin
OBJECTIVE: To describe radical cystectomy followed by cutaneous ureterostomy as a treatment of invasive bladder neoplasia in dogs. STUDY DESIGN: Retrospective study. ANIMALS: Client-owned dogs with transitional cell carcinoma of the bladder trigone (n=4). METHODS: Perioperative complications and long-term outcomes of dogs that underwent cutaneous ureterostomy following radical cystectomy and lymphadenectomy for transitional cell carcinoma of the urinary bladder trigone were reviewed...
December 1, 2016: Veterinary Surgery: VS
https://www.readbyqxmd.com/read/27911460/retrospective-comparison-of-two-different-approaches-for-ultrasound-guided-internal-jugular-vein-cannulation-in-hemodialysis-patients
#4
Antonio Treglia, Dario Musone, Francesco Amoroso
BACKGROUND: Prevalent hemodialysis patients with vascular access consisting of a central venous catheter (CVC) are continuously increasing over the years. Improvement in evolution and CVC placement procedures represents therefore an essential tool to enhance performance and reduce intraoperative and long-term CVC complications. Internal jugular vein (IJV) catheterization techniques are different according to ultrasound probe position in relation to vein axis and to needle direction in relation to ultrasound beam...
December 2, 2016: Journal of Vascular Access
https://www.readbyqxmd.com/read/27911456/mid-term-results-of-recap-magnum-taperloc-metal-on-metal-total-hip-arthroplasty-with-mean-follow-up-of-7-1-years
#5
Antonios A Koutalos, Aristotelis Kourtis, Ian C Clarke, Evert J Smith
INTRODUCTION: Despite enthusiasm for metal-on-metal bearings, disappointing short- to mid-term outcomes has all but halted the use of this bearing articulation. This review presents mid-term results for the ReCap Magnum total hip replacement. PATIENTS AND METHODS: This prospective study evaluated 79 ReCap/Magnum/Taperloc total hip replacements with mean follow-up of 7.1 (range 3.7-9.2) years. 43 were female and 36 male. Metal ions were measured and radiographic measurement included a 'margin of safety' angle to quantify risk of edge loading...
December 2, 2016: Hip International: the Journal of Clinical and Experimental Research on Hip Pathology and Therapy
https://www.readbyqxmd.com/read/27911446/treatment-patterns-of-ranibizumab-intravitreal-injection-and-dexamethasone-intravitreal-implant-for-retinal-vein-occlusion-in-the-usa
#6
S Nghiem-Buffet, S Baillif, S Regnier, A Skelly, N Yu, A Sodi
PurposeRanibizumab, an anti-vascular endothelial growth factor, and dexamethasone, a corticosteroid, have been shown to be effective in treating macular oedema secondary to retinal vein occlusion (RVO) (central RVO (CRVO) and branch RVO (BRVO)). Their real-world usage, however, has yet to be compared. We therefore evaluated ophthalmology visits for both drugs using US patient-level data.MethodsThe IMS Health Real-World Data Medical Claims database was used to identify treatment-naive patients receiving ranibizumab intravitreal injections or dexamethasone intravitreal implants between June 2010 and February 2014 who had 12 months of follow-up data...
December 2, 2016: Eye
https://www.readbyqxmd.com/read/27911424/-effectiveness-of-soft-contact-lenses-in-severe-keratoconjunctivitis-sicca-treated-with-local-immunosuppressive-therapy
#7
T N Safonova, O V Gladkova, V I Boev, A A Fedorov
AIM: To study the effectiveness of soft contact lenses in severe keratoconjunctivitis sicca (KCS) treated with local immunosuppressive therapy. MATERIAL AND METHODS: We have examined 41 patients (60 eyes) with severe KCS, including 3 men (4 eyes) and 38 women (56 eyes) aged from 27 to 76 years. Group 1 consisted of 22 persons (30 eyes) who were prescribed cyclosporine А 0.05% instillations 2 times daily, artificial tears, and soft contact lenses. Group 2 consisted of 19 patients (30 eyes) who received instillations of cyclosporine А 0...
2016: Vestnik Oftalmologii
https://www.readbyqxmd.com/read/27911302/association-between-cognitive-status-before-surgery-and-outcomes-in-elderly-patients-with-hip-fracture-in-a-dedicated-orthogeriatric-care-pathway
#8
Lorene Zerah, Judith Cohen-Bittan, Mathieu Raux, Anthony Meziere, Cendrine Tourette, Christian Neri, Marc Verny, Bruno Riou, Frederic Khiami, Jacques Boddaert
BACKGROUND: Dementia is associated with a worse prognosis of hip fracture, but the impact of a dedicated geriatric care pathway on the prognosis of these patients has not been evaluated. OBJECTIVE: According to the cognitive status before surgery, our main objective was to compare mortality rate at 6 months; secondary outcomes were to compare in-hospital complications, the risk of new institutionalization, and the ability to walk at 6 months. METHODS: Between 2009 and 2015, all patients (>70 years) admitted after hip fracture surgery into a dedicated unit of peri-operative geriatric care were included: patients with dementia (DP), without dementia (NDP), and with cognitive status not determined (CSND)...
November 28, 2016: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/27911274/high-expression-of-mucin13-associates-with-grimmer-postoperative-prognosis-of-patients-with-non-metastatic-clear-cell-renal-cell-carcinoma
#9
Zhiying Xu, Yidong Liu, Yuanfeng Yang, Jieti Wang, Guodong Zhang, Zheng Liu, Hangcheng Fu, Zewei Wang, Haiou Liu, Jiejie Xu
BACKGROUND: Mucin13 (MUC13) is a transmembrane glycoprotein that is aberrantly expressed in ovarian and gastro-intestinal tumors, but its role in renal cell carcinoma remains elusive. The purpose of this study is to evaluate the prognostic value of MUC13 expression in patients with non-metastatic clear cell renal cell carcinoma (ccRCC) after surgical resection. RESULTS: MUC13 high expression was associated with high Fuhrman grade (p < 0.001), high SSIGN score (p = 0...
November 29, 2016: Oncotarget
https://www.readbyqxmd.com/read/27911262/magnetic-resonance-elastography-vs-transient-elastography-in-detection-of-fibrosis-and-noninvasive-measurement-of-steatosis-in-patients-with-biopsy-proven-nonalcoholic-fatty-liver-disease
#10
Charlie C Park, Phirum Nguyen, Carolyn Hernandez, Ricki Bettencourt, Kimberly Ramirez, Lynda Fortney, Jonathan Hooker, Ethan Sy, Mosab H Alquiraish, Mark A Valasek, Emily Rizo, Lisa Richards, David Brenner, Claude B Sirlin, Rohit Loomba
BACKGROUND & AIMS: Magnetic-resonance-imaging (MRI) techniques and ultrasound-based transient elastography (TE) can be used in noninvasive diagnosis of fibrosis and steatosis in patients with nonalcoholic fatty liver disease (NAFLD). We performed a prospective study to compare the performance of magnetic resonance elastography (MRE) vs TE for in diagnosis of fibrosis, and MRI-based proton density fat fraction (MRI-PDFF) analysis vs TE-based controlled attenuation parameter (CAP) for diagnosis of steatosis in patients undergoing biopsy to assess NAFLD...
October 27, 2016: Gastroenterology
https://www.readbyqxmd.com/read/27911239/microvascular-decompression-of-the-cochleovestibular-nerve-for-treatment-of-tinnitus-and-vertigo-a-systematic-review-and-meta-analysis-of-individual-patient-data
#11
Minke J C van den Berge, J Marc C van Dijk, Iris A Posthumus, Nynke Smidt, Pim van Dijk, Rolien H Free
OBJECTIVE Microvascular decompression (MVD) is regarded as a valid treatment modality in neurovascular conflicts (NVCs) causing, for example, trigeminal neuralgia and hemifacial spasms. An NVC of the cochleovestibular nerve might cause tinnitus and/or vertigo; however, general acceptance of MVD for this indication is lacking. The aim of this study was to investigate the effectiveness, safety, and prognostic factors for success of MVD of the cochleovestibular nerve. METHODS A systematic review and meta-analysis of individual patient data (IPD) were conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses and Individual Patient Data (PRISMA-IPD) guidelines...
December 2, 2016: Journal of Neurosurgery
https://www.readbyqxmd.com/read/27911236/patient-versus-physician-reported-facial-disability-in-vestibular-schwannoma-an-international-cross-sectional-study
#12
Øystein Vesterli Tveiten, Matthew L Carlson, Frederik Goplen, Erling Myrseth, Colin L W Driscoll, Rupavathana Mahesparan, Michael J Link, Morten Lund-Johansen
OBJECTIVE Patient-reported outcomes are increasingly used in studies of vestibular schwannoma (VS); however, few studies have examined self-evaluated facial nerve function and its relation to physician-reported outcomes. The primary objective of this study was to compare patient self-evaluations of facial disability with physician-evaluated facial nerve status and with self-evaluations of a healthy control group. The second objective was to provide insight into the controversial subject of the optimal initial management of small- and medium-sized VSs; consequently, the authors compared patient-reported facial nerve disability following treatment via observation (OBS), Gamma Knife surgery (GKS), or microsurgery (MS)...
December 2, 2016: Journal of Neurosurgery
https://www.readbyqxmd.com/read/27911139/volumetric-response-of-intracranial-meningioma-after-photon-or-particle-irradiation
#13
Petra Mozes, Jan Oliver Dittmar, Daniel Habermehl, Eric Tonndorf-Martini, Katalin Hideghety, Anne Dittmar, Jürgen Debus, Stephanie E Combs
BACKGROUND: Meningiomas are usually slow growing, well circumscribed intracranial tumors. In symptom-free cases observation with close follow-up imaging could be performed. Symptomatic meningiomas could be surgically removed and/or treated with radiotherapy. The study aimed to evaluate the volumetric response of intracranial meningiomas at different time points after photon, proton, and a mixed photon and carbon ion boost irradiation. PATIENTS AND METHODS: In Group A 38 patients received proton therapy (median dose: 56 GyE in 1...
December 2, 2016: Acta Oncologica
https://www.readbyqxmd.com/read/27911114/changes-of-tangential-traction-after-macular-peeling-correlation-between-en-face-analysis-and-macular-sensitivity
#14
Mario R Romano, Gilda Cennamo, Ida Cesarano, Domenico Cardone, Giuseppe Nicoletti, Rodolfo Mastropasqua, Giovanni Cennamo
PURPOSE: To assess the epi- and intra-retinal morphology changes of the tangential tractions following vitreoretinal surgery for epiretinal membranes and to investigate the correlation between the depth of retinal changes and functional macular sensitivity (MS). METHODS: This is a prospective cross-sectional interventional study, in which 73 eyes of 73 patients with diagnosis of idiopathic epiretinal membrane (iERM) were evaluated. All patients received complete ophthalmic evaluation, including axial and en-face scanning spectral domain-optical coherence tomography (SD-OCT) analysis and microperimetry...
December 2, 2016: Current Eye Research
https://www.readbyqxmd.com/read/27911111/outcomes-of-scleral-buckle-removal-experience-from-the-last-decade
#15
Elad Moisseiev, Miri Fogel, Ido Didi Fabian, Adiel Barak, Joseph Moisseiev, Amir Alhalel
PURPOSE: To evaluate the indications, outcomes, and complications of scleral buckle removal over the past decade and compare to previously published data. METHODS: Forty nine eyes of 49 patients who underwent scleral buckle removal and had at least 6 months of follow-up were included in this retrospective study. Recorded parameters included demographic information, history of the retinal detachment, details of the scleral buckling surgery, indication for scleral buckle removal, time from scleral buckle placement to removal, culture results, length of follow up, visual acuity (VA) throughout the follow up, and the occurrence of any complications or need for additional surgery after scleral buckle removal...
December 2, 2016: Current Eye Research
https://www.readbyqxmd.com/read/27911096/evaluating-health-advice-in-a-web-2-0-environment-the-impact-of-multiple-user-generated-factors-on-hiv-advice-perceptions
#16
Joseph B Walther, Jeong-Woo Jang, Ashley A Hanna Edwards
Unlike traditional media, social media systems often present information of different types from different kinds of contributors within a single message pane, a juxtaposition of potential influences that challenges traditional health communication processing. One type of social media system, question-and-answer advice systems, provides peers' answers to health-related questions, which yet other peers read and rate. Responses may appear good or bad, responders may claim expertise, and others' aggregated evaluations of an answer's usefulness may affect readers' judgments...
December 2, 2016: Health Communication
https://www.readbyqxmd.com/read/27911025/effect-of-balloon-expandable-transcatheter-aortic-valve-replacement-positioning-a-patient-specific-numerical-model
#17
Matteo Bianchi, Gil Marom, Ram P Ghosh, Harold A Fernandez, James R Taylor, Marvin J Slepian, Danny Bluestein
Transcatheter aortic valve replacement (TAVR) has emerged as a life-saving and effective alternative to surgical valve replacement in high-risk, elderly patients with severe calcific aortic stenosis. Despite its early promise, certain limitations and adverse events, such as suboptimal placement and valve migration, have been reported. In the present study, it was aimed to evaluate the effect of various TAVR deployment locations on the procedural outcome by assessing the risk for valve migration. The deployment of a balloon-expandable Edwards SAPIEN valve was simulated via finite element analysis in a patient-specific calcified aortic root, which was reconstructed from CT scans of a retrospective case of valve migration...
December 2016: Artificial Organs
https://www.readbyqxmd.com/read/27911019/the-impact-and-measurement-of-social-dysfunction-in-late-life-depression-an-evaluation-of-current-methods-with-a-focus-on-wearable-technology
#18
REVIEW
Sophie Hodgetts, Peter Gallagher, Daniel Stow, I Nicol Ferrier, John T O'Brien
OBJECTIVE: Depression is known to negatively impact social functioning, with patients commonly reporting difficulties maintaining social relationships. Moreover, a large body of evidence suggests poor social functioning is not only present in depression but that social functioning is an important factor in illness course and outcome. In addition, good social relationships can play a protective role against the onset of depressive symptoms, particularly in late-life depression. However, the majority of research in this area has employed self-report measures of social function...
December 2, 2016: International Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/27911009/echocardiographic-predictors-of-outcome-in-patients-with-chronic-obstructive-pulmonary-disease
#19
Ivan Stankovic, Robert Marcun, Aleksandra Janicijevic, Jerneja Farkas, Sasa Kadivec, Ivan Ilic, Aleksandar N Neskovic, Mitja Lainscak
BACKGROUND: We aimed to assess the relationship between echocardiographic characteristics and mortality in patients with chronic obstructive pulmonary disease (COPD). METHODS: We prospectively studied 154 patients (mean age 71 ± 10 years, 71% male) with COPD. All patients underwent transthoracic Doppler echocardiography within 48 hours of hospital admission. Primary endpoint was all-cause mortality during a median period of 22 months. RESULTS: Mildly elevated tricuspid regurgitation pressure and mitral E/e' ratio were the most commonly encountered echocardiographic abnormalities, observed in 60% and 56% of patients, respectively...
December 2, 2016: Journal of Clinical Ultrasound: JCU
https://www.readbyqxmd.com/read/27911002/what-is-quality-of-life-and-how-do-we-measure-it-relevance-to-parkinson-s-disease-and-movement-disorders
#20
REVIEW
Pablo Martinez-Martin
Health-related quality of life is a patient-reported outcome that complements clinical evaluation and provides information about disease activity and effects of the treatment. The objective of this review is to present the conceptual framework, the measures, and some of their most relevant applications in the field of Parkinson's disease and movement disorders. Health-related quality of life is a subjective, individual, and multidimensional construct, and its main dimensions are physical, mental, and social, besides global perceptions of health and personal domains...
December 2, 2016: Movement Disorders: Official Journal of the Movement Disorder Society
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