keyword
MENU ▼
Read by QxMD icon Read
search

Erectile, cholesterol

keyword
https://www.readbyqxmd.com/read/27819758/effect-of-tadalafil-5mg-daily-treatment-on-the-ejaculatory-times-lower-urinary-tract-symptoms-and-erectile-function-in-patients-with-erectile-dysfunction
#1
Mehmet Karabakan, Ercument Keskin, Serkan Akdemir, Aliseydi Bozkurt
OBJECTIVE: To investigate the effect of a 5mg daily tadalafil treatment on the ejaculation time, erectile function and lower urinary tract symptoms (LUTS) in patients with erectile dysfunction. MATERIALS AND METHODS: A total of 60 patients diagnosed with erectile dysfunction were retrospectively evaluated using the international index of erectile function questionnaire-5 (IIEF-5), intravaginal ejaculatory latency time (IELT) and international prostate symptoms scores (IPSS)...
November 2, 2016: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/27619893/hyperlipidemia-impairs-erectile-function-in-rats-by-causing-cavernosal-fibrosis
#2
R Li, K Cui, T Wang, S Wang, X Li, J Qiu, G Yu, J Liu, B Wen, K Rao
Men with hyperlipidemia are more likely to have erectile dysfunction (ED) than those without hyperlipidemia, but the mechanisms are not fully understood. The aim of this study was to investigate the underlying mechanism of ED caused by hyperlipidemia. Fourteen 8-week-old Sprague-Dawley rats were randomly divided into two groups: a control group and a hyperlipidemia group (fed chow containing 4% cholesterol and 1% cholic acid). After 6 months, we assessed erectile function by performing cavernous nerve electrostimulation followed by intracavernosal pressure/mean arterial pressure measurements, as well as plasma lipid profile assessment in all rats...
September 13, 2016: Andrologia
https://www.readbyqxmd.com/read/27562011/thiol-disulphide-homeostasis-levels-in-erectile-dysfunction-patients
#3
Y Ustundag-Budak, M Sambel, M Alisik, M Aydos, O Erel, S Oner, M Demirbas, M Kilic, D Unal
This study explored the use of thiol/disulphide homeostasis as a novel oxidative stress marker in patients with erectile dysfunction (ED). Fifty-five patients aged 40-57 were divided into two groups: Group I (International Index of Erectile Function [IIEF-5] score between 22 and 25, n = 20) and Group II (IIEF-5 score < 22, n = 35). Blood samples were used to evaluate hormone levels, lipid profile and thiol/disulphide levels. A novel, fully automated method measured plasma native thiol, total thiol and disulphide levels...
August 26, 2016: Andrologia
https://www.readbyqxmd.com/read/27513408/effects-of-resveratrol-on-the-alterations-of-cavernosal-enos-and-lox-1-expression-in-the-hypercholesterolemic-condition-a-preliminary-study
#4
Ozan Bozkurt, Aykut Kefi, Ömer Demir, Nergis Murat, Sedef Gidener, Ahmet Adil Esen
BACKGROUND/AIM: The aim of this study was to determine the effects of resveratrol on the alterations of cavernosal eNOS and LOX-1 mRNA expression in the hypercholesterolemic condition. MATERIALS AND METHODS: Twenty-one New Zealand white male rabbits were separated into three groups. Rabbits were fed with a normal dietary intake for the control group and a 2% cholesterol diet for the hypercholesterolemia and resveratrol groups for 6 weeks. Resveratrol 4 mg/kg daily was administered for the resveratrol group...
2016: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/27468624/-mechanism-of-rhoa-rho-kinase-signal-pathway-induced-erectile-dysfunction-in-hyperlipidemic-rats
#5
R Li, K Cui, T Wang, S G Wang, W M Yang, J H Liu, K Rao
OBJECTIVE: To investigate the expression of RhoA/Rho-kinase (ROCK) in penile corpus cavernosum smooth muscles in rats of hyperlipidemia-induced erectile dysfunction and its molecular mechanism. METHODS: Forty male Sprague-Dawley rats were randomly divided into control and experimental groups using a random number table. Rats in the control group (n=20) were fed with regular diet for 24 weeks and those in the experimental group (n=20) with high-fat diet for the same period of time...
July 12, 2016: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/27439215/improvement-of-endothelial-function-in-a-murine-model-of-mild-cholesterol-induced-atherosclerosis-by-mineralocorticoid-antagonism
#6
Mario T Kratz, Stephan H Schirmer, Magnus Baumhäkel, Michael Böhm
BACKGROUND AND AIMS: The renin-angiotensin-aldosterone-system (RAAS) plays a role in endothelial dysfunction and atherosclerosis. During treatment with RAAS-inhibitors, elevated aldosterone may sustain "aldosterone escape". METHODS: We investigated the effects of treatment with the mineralocorticoid antagonist eplerenone (Ep) compared with ramipril (Rami) or the combination of both on oxidative stress, plaque formation and endothelial function, in atherosclerotic apolipoprotein E deficient mice (ApoE(-/-)-mice)...
August 2016: Atherosclerosis
https://www.readbyqxmd.com/read/27436076/effects-of-8-year-treatment-of-long-acting-testosterone-undecanoate-on-metabolic-parameters-urinary-symptoms-bone-mineral-density-and-sexual-function-in-men-with-late-onset-hypogonadism
#7
Sompol Permpongkosol, Kalayanee Khupulsup, Supatra Leelaphiwat, Sarawan Pavavattananusorn, Supranee Thongpradit, Thanom Petchthong
INTRODUCTION: The long-term effects of long-acting testosterone undecanoate (TU) and androgen receptor CAG repeat lengths in Thai men with late-onset hypogonadism (LOH) have not been reported. AIM: To analyze the 8-year follow-up effects of intramuscular TU therapy on metabolic parameters, urinary symptoms, bone mineral density, and sexual function and investigate CAG repeat lengths in men with LOH. METHODS: We reviewed the medical records of 428 men with LOH who had been treated with TU and 5 patients were diagnosed with prostate cancer during TU therapy...
August 2016: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/27172660/-risk-factors-of-erectile-dysfunction-in-patients-with-cardiovascular-diseases
#8
Jun-ping Xing, Liang Ning, Hui-ming Chen, Tan Tan
OBJECTIVE: To investigate the penile erectile function of hospitalized male patients with cardiovascular diseases, the incidence of erectile dysfunction (ED) in this cohort, and the relationship of ED with cardiovascular diseases and its risk factors. METHODS: Using a self-designed questionnaire, we conducted an investigation among the hospitalized patients in the Department of Cardiovascular Diseases of the First and Second Affiliated Hospitals of Xi'an Jiaotong University...
March 2016: Zhonghua Nan Ke Xue, National Journal of Andrology
https://www.readbyqxmd.com/read/27125688/the-synergy-effect-of-daidzein-and-genistein-isolated-from-butea-superba-roxb-on-the-reproductive-system-of-male-mice
#9
Griangsak Eumkeb, Sudarat Tanphonkrang, Kittipot Sirichaiwetchakoon, Tanaporn Hengpratom, Wanatkamon Naknarong
Butea superba Roxb. (BS) has been used in Thai men as an aphrodisiac, and prevent erectile dysfunction. Nevertheless, the active ingredients, dosages, have not been cleared. Hence, this study was to investigate the effect of compounds from the BS on the reproductive parameters of male mice. The results revealed that BS was extracted to afford biochanin A and genistein, which were first reported on BS, and daidzein. The mice were treated by daidzein and genistein alone and in combination. The results showed that the sperm number and motility, cholesterol and testosterone level of all isoflavones-treated groups were significantly higher than controls (p < 0...
April 29, 2016: Natural Product Research
https://www.readbyqxmd.com/read/27052235/-sex-and-gender-aspects-in-regard-to-clinical-practice-recommendations-for-pre-diabetes-and-diabetes
#10
Alexandra Kautzky-Willer, Heidemarie Abrahamian, Raimund Weitgasser, Peter Fasching, Fritz Hoppichler, Monika Lechleitner
Metabolic diseases dramatically affect life of men and women from infancy up to old age and are a major challenge for clinicians. Health professionals are confronted with different needs of women and men. This article aims at an increase of gender awareness and the implementation of current knowledge of gender medicine in daily clinical practice with regard to pre-diabetes and diabetes. Sex and gender affect screening and diagnosis of metabolic diseases as well as treatment strategies and outcome. Impaired glucose and lipid metabolism, regulation of energy balance and body fat distribution are related to steroid hormones and therefore impose their influence on cardiovascular health in both men and women...
April 2016: Wiener Klinische Wochenschrift
https://www.readbyqxmd.com/read/26960674/risk-factors-for-erectile-dysfunction-in-patients-with-cardiovascular-disease
#11
Rakesh Kumar Chaudhary, Bilal Haider Shamsi, Hui-Ming Chen, Tan Tan, Kai-Fa Tang, Jun-Ping Xing
OBJECTIVE: To examine the relationship between risk factors for cardiac disease and erectile dysfunction (ED) in men from Xi'an, China. METHODS: Participants were patients with cardiovascular disease who visited the Cardiovascular Medicine Department of Xi'an Jiaotong University First Affiliated Hospital between September 2011 and March 2012. Two hundred and fifty patients were issued with questionnaires and underwent a physical examination and blood test.Risk factors for ED were identified using univariate and multivariate analyses...
June 2016: Journal of International Medical Research
https://www.readbyqxmd.com/read/26812302/sac-1004-a-pseudo-sugar-derivative-of-cholesterol-restores-erectile-function-through-reconstruction-of-nonleaky-and-functional-cavernous-angiogenesis-in-the-streptozotocin-induced-diabetic-mouse
#12
Dulguun Batbold, Kang-Moon Song, Jin-Mi Park, Soo-Hwan Park, Tack Lee, Dong-Soo Ryu, Young-Ger Suh, Young-Guen Kwon, Ji-Kan Ryu, Jun-Kyu Suh
PURPOSE: We examined whether and how Sac-1004, a vascular leakage blocker, would restore erectile function in an animal model of diabetic erectile dysfunction. MATERIALS AND METHODS: Eight-week-old C57BL/6J mice were used. Diabetes was induced by intraperitoneal injection of streptozotocin. Eight weeks after diabetes induction the animals were divided into 6 groups, including controls, diabetic mice that received repeat intracavernous injections of phosphate buffered saline (20 μl) on days -3 and 0, and diabetic mice that received repeat intracavernous injections of Sac-1004 on days -3 and 0 (1, 2, 5 and 10 μg, respectively, in 20 μl phosphate buffered saline)...
June 2016: Journal of Urology
https://www.readbyqxmd.com/read/26803454/melatonin-improves-erectile-function-in-rats-with-chronic-lower-body-ischemia
#13
Norifumi Sawada, Masanori Nomiya, Mona Zarifpour, Takahiko Mitsui, Masayuki Takeda, Karl-Erik Andersson
INTRODUCTION: Arterial occlusive disease is the leading cause of erectile dysfunction (ED). Using an established rat model we wanted to characterize the changes caused by atherosclerosis-induced chronic ischemia on penile structures and erectile function. AIM: To investigate the effect of melatonin on these parameters. METHODS: Adult male Sprague-Dawley rats were divided into control, arterial injury (AI) and AI with melatonin treatment groups...
February 2016: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/26784833/solid-lipid-nanoparticles-for-transdermal-delivery-of-avanafil-optimization-formulation-in-vitro-and-ex-vivo-studies
#14
Mallesh Kurakula, Osama A A Ahmed, Usama A Fahmy, Tarek A Ahmed
CONTEXT: Avanafil (AVA) is used in the treatment of erectile dysfunction, but is reported for its poor aqueous solubility. Solid lipid nanoparticles (SLNs) are lipid carriers that can greatly enhance drug solubility and bioavailability. OBJECTIVE: This work was aimed to formulate and optimize AVA SLNs with subsequent loading into hydrogel films for AVA transdermal delivery. MATERIALS AND METHODS: AVA SLNs were prepared utilizing homogenization followed by ultra-sonication technique...
December 2016: Journal of Liposome Research
https://www.readbyqxmd.com/read/26758995/hypovitaminosis-d-is-associated-with-erectile-dysfunction-in-type-2-diabetes
#15
Nicola Caretta, Saula Vigili de Kreutzenberg, Umberto Valente, Gabriella Guarneri, Alberto Ferlin, Angelo Avogaro, Carlo Foresta
Diabetes is an established risk factor for erectile dysfunction (ED). The pathophysiology of ED in diabetic men is multifactorial, but it mainly involves a vascular disorder related to a reduction of endothelial function. Recently, several studies have correlated ED risk factors with vitamin D deficiency. In this study, we evaluate the relationship between 25-hydroxyvitamin D [25(OH)D] levels, erectile dysfunction, and vascular disease, in type 2 diabetes mellitus men (T2DM). In this observational study, 92 T2DM males (58...
September 2016: Endocrine
https://www.readbyqxmd.com/read/26685713/association-between-serum-fetuin-a-level-and-erectile-function
#16
M Karabakan, A Bozkurt, M Gunay, B K Aktas, E Hirik, M Aydın, B Nuhoglu
Recent studies have shown that ED is an early symptom of atherosclerosis. Fetuin-A, a glycoprotein secreted by the liver, kidneys and choroid plexus, has been linked to systemic fibrosis and calcification in human and rat studies. Deficiency of this compound may play a role in atherosclerosis and cardiovascular disease progression. The aim of the study was to examine whether serum fetuin-A level is related to erectile function or severity of ED. Sixty ED patients without cardiovascular disease were assigned to one of the three groups (mild, moderate or severe ED) depending on ED severity...
September 2016: Andrologia
https://www.readbyqxmd.com/read/26527360/elevated-plasma-aldosterone-is-an-independent-risk-factor-for-erectile-dysfunction-in-men
#17
Fei Wu, Shanhua Mao, Tianfang Yu, Haowen Jiang, Qiang Ding, Gang Xu
INTRODUCTION: Erectile dysfunction (ED) and cardiovascular disease (CVD) share a great number of common risk factors. There is growing evidence that aldosterone, an independent CVD risk factor, is associated with ED. AIMS: The purpose of this study was to determine the relationship between plasma aldosterone and erectile dysfunction. METHODS: This study recruited 287 participants, ranging from 18 to 84 years old; 217 were suffering from ED, diagnosed by the International Index of Erectile Function 5 (IIEF-5) scores...
July 2016: World Journal of Urology
https://www.readbyqxmd.com/read/26413340/is-there-a-relationship-between-the-severity-of-erectile-dysfunction-and-the-comorbidity-profile-in-men-with-late-onset-hypogonadism
#18
Aksam A Yassin, Joanne E Nettleship, Yousef Almehmadi, Dany-Jan Yassin, Youssef El Douaihy, Farid Saad
OBJECTIVE: To determine whether the severity of erectile dysfunction (ED) in a man diagnosed with late-onset hypogonadism (LOH) gives information about his metabolic syndrome state, as patients with LOH often have sexual symptoms and associated cardiovascular and metabolic comorbidities, but the role of ED in predicting the prevalence of comorbid disease in men with low levels of testosterone is currently unknown. PATIENTS AND METHODS: Men (130) diagnosed with LOH and fulfilling the criteria of a total testosterone level of <3...
September 2015: Arab Journal of Urology
https://www.readbyqxmd.com/read/26328190/the-relationships-between-metabolic-syndrome-erectile-dysfunction-and-lower-urinary-tract-symptoms-associated-with-benign-prostatic-hyperplasia
#19
Yunus Doğan, Fatih Uruç, Bekir Aras, Aytaç Şahin, Mithat Kıvrak, Ahmet Ürkmez, Numan Doğu Güner, Sabahattin Aydın
OBJECTIVE: To determine the relationship between erectile dysfunction and metabolic syndrome (MetS) in patients with benign prostatic hyperplasia (BPH) and lower urinary tract symptoms (LUTS). MATERIAL AND METHODS: Seventy-eight patients who were admitted to our outpatient clinic because of BPH-related LUTS over 40 years of age were included in the study. Patients with LUTS and erectile dysfunction (ED) were evaluated by International Prostate Symptom Score (IPSS) and International Index of Erectile Function-5 (IIEF-5) forms...
March 2015: Turkish Journal of Urology
https://www.readbyqxmd.com/read/26302884/association-between-serum-folic-acid-level-and-erectile-dysfunction
#20
M Karabakan, A E Erkmen, O Guzel, B K Aktas, A Bozkurt, S Akdemir
This study measured the serum folic acid (FA) level in patients with erectile dysfunction (ED) and evaluated the possible association between the serum FA level and erectile function. The study divided 120 patients with ED into 3 groups of 40 patients each: those with severe, moderate and mild ED. Forty healthy men served as controls. Fasting serum samples were obtained, and the total testosterone, cholesterol and FA levels were measured using chemiluminescent immunoassays. There were no significant differences in the mean age, mean body mass index or mean serum total testosterone and cholesterol levels among the three ED groups and controls (P > 0...
June 2016: Andrologia
keyword
keyword
36251
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"