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https://www.readbyqxmd.com/read/28738624/multiplexed-analysis-combining-distinctly-sized-cdte-mpa-quantum-dots-and-chemometrics-for-multiple-mutually-interfering-analyte-determination
#1
Dayana B Bittar, David S M Ribeiro, Ricardo N M J Páscoa, José X Soares, S Sofia M Rodrigues, Rafael C Castro, Leonardo Pezza, Helena R Pezza, João L M Santos
Semiconductor quantum dots (QDs) have demonstrated a great potential as fluorescent probes for heavy metals monitoring. However, their great reactivity, whose tunability could be difficult to attain, could impair selectivity yielding analytical results with poor accuracy. In this work, the combination in the same analysis of multiple QDs, each with a particular ability to interact with the analyte, assured a multi-point detection that was not only exploited for a more precise analyte discrimination but also for the simultaneous discrimination of multiple mutually interfering species, in the same sample...
November 1, 2017: Talanta
https://www.readbyqxmd.com/read/28738563/urinary-volatile-fingerprint-based-on-mass-spectrometry-for-the-discrimination-of-patients-with-lung-cancer-and-controls
#2
Álvaro García Ramos, Ana Pérez Antón, Miguel Del Nogal Sánchez, José Luis Pérez Pavón, Bernardo Moreno Cordero
Profile signals of urine samples corresponding to patients with lung cancer and controls were obtained using a non-separative methodology. The method is based on the coupling of a headspace sampler, a programed temperature vaporizer and a mass spectrometer (HS-PTV-MS). With only a centrifugation step as prior sample treatment, the samples were subjected to the headspace generation process and the volatiles generated were introduced into the PTV where they were trapped in the Tenax® packed liner while the solvent was purged...
November 1, 2017: Talanta
https://www.readbyqxmd.com/read/28738558/elemental-source-attribution-signatures-for-calcium-ammonium-nitrate-can-fertilizers-used-in-homemade-explosives
#3
Carlos G Fraga, Alexander V Mitroshkov, Nikhil S Mirjankar, Brian P Dockendorff, Angie M Melville
Calcium ammonium nitrate (CAN) is a widely available fertilizer composed of ammonium nitrate (AN) mixed with some form of calcium carbonate such as limestone or dolomite. CAN is also frequently used to make homemade explosives. The potential of using elemental profiling and chemometrics to match both pristine and reprocessed CAN fertilizers to their factories of origin for use in future forensic investigations was examined. Inductively coupled plasma-mass spectrometry (ICP-MS) was used to determine the concentrations of 64 elements in 125 samples from 11 CAN stocks from 6 different CAN factories...
November 1, 2017: Talanta
https://www.readbyqxmd.com/read/28738459/-gene-gene-interaction-on-central-obesity-in-school-aged-children-in-china
#4
L W Fu, M X Zhang, L J Wu, L W Gao, J Mi
Objective: To investigate possible effect of 6 obesity-associated SNPs in contribution to central obesity and examine whether there is an interaction in the 6 SNPs in the cause of central obesity in school-aged children in China. Methods: A total of 3 502 school-aged children who were included in Beijing Child and Adolescent Metabolic Syndrome (BCAMS) Study were selected, and based on the age and sex specific waist circumference (WC) standards in the BCAMS study, 1 196 central obese cases and 2 306 controls were identified...
July 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/28738313/high-throughput-phenotyping-to-accelerate-crop-breeding-and-monitoring-of-diseases-in-the-field
#5
REVIEW
Nadia Shakoor, Scott Lee, Todd C Mockler
Effective implementation of technology that facilitates accurate and high-throughput screening of thousands of field-grown lines is critical for accelerating crop improvement and breeding strategies for higher yield and disease tolerance. Progress in the development of field-based high throughput phenotyping methods has advanced considerably in the last 10 years through technological progress in sensor development and high-performance computing. Here, we review recent advances in high throughput field phenotyping technologies designed to inform the genetics of quantitative traits, including crop yield and disease tolerance...
July 21, 2017: Current Opinion in Plant Biology
https://www.readbyqxmd.com/read/28738126/comparing-plasma-phospho-tau-total-tau-and-phospho-tau-total-tau-ratio-as-acute-and-chronic-traumatic-brain-injury-biomarkers
#6
Richard Rubenstein, Binggong Chang, John K Yue, Allen Chiu, Ethan A Winkler, Ava M Puccio, Ramon Diaz-Arrastia, Esther L Yuh, Pratik Mukherjee, Alex B Valadka, Wayne A Gordon, David O Okonkwo, Peter Davies, Sanjeev Agarwal, Fan Lin, George Sarkis, Hamad Yadikar, Zhihui Yang, Geoffrey T Manley, Kevin K W Wang, Shelly R Cooper, Kristen Dams-O'Connor, Allison J Borrasso, Tomoo Inoue, Andrew I R Maas, David K Menon, David M Schnyer, Mary J Vassar
Importance: Annually in the United States, at least 3.5 million people seek medical attention for traumatic brain injury (TBI). The development of therapies for TBI is limited by the absence of diagnostic and prognostic biomarkers. Microtubule-associated protein tau is an axonal phosphoprotein. To date, the presence of the hypophosphorylated tau protein (P-tau) in plasma from patients with acute TBI and chronic TBI has not been investigated. Objective: To examine the associations between plasma P-tau and total-tau (T-tau) levels and injury presence, severity, type of pathoanatomic lesion (neuroimaging), and patient outcomes in acute and chronic TBI...
July 24, 2017: JAMA Neurology
https://www.readbyqxmd.com/read/28738088/virtual-daily-living-test-to-screen-for-mild-cognitive-impairment-using-kinematic-movement-analysis
#7
Kyoungwon Seo, Jae-Kwan Kim, Dong Hoon Oh, Hokyoung Ryu, Hojin Choi
Questionnaires or computer-based tests for assessing activities of daily living are well-known approaches to screen for mild cognitive impairment (MCI). However, questionnaires are subjective and computerized tests only collect simple performance data with conventional input devices such as a mouse and keyboard. This study explored the validity and discriminative power of a virtual daily living test as a new diagnostic approach to assess MCI. Twenty-two healthy controls and 20 patients with MCI were recruited...
2017: PloS One
https://www.readbyqxmd.com/read/28738063/atypical-speech-versus-non-speech-detection-and-discrimination-in-4-to-6-yr-old-children-with-autism-spectrum-disorder-an-erp-study
#8
Alena Galilee, Chrysi Stefanidou, Joseph P McCleery
Previous event-related potential (ERP) research utilizing oddball stimulus paradigms suggests diminished processing of speech versus non-speech sounds in children with an Autism Spectrum Disorder (ASD). However, brain mechanisms underlying these speech processing abnormalities, and to what extent they are related to poor language abilities in this population remain unknown. In the current study, we utilized a novel paired repetition paradigm in order to investigate ERP responses associated with the detection and discrimination of speech and non-speech sounds in 4- to 6-year old children with ASD, compared with gender and verbal age matched controls...
2017: PloS One
https://www.readbyqxmd.com/read/28738057/the-fatty-liver-index-as-a-predictor-of-incident-chronic-kidney-disease-in-a-10-year-prospective-cohort-study
#9
Ji Hye Huh, Jang Young Kim, Eunhee Choi, Jae Seok Kim, Yoosoo Chang, Ki-Chul Sung
BACKGROUND: Although non-alcoholic fatty liver disease (NAFLD) is considered to be associated with chronic kidney disease (CKD), long-term follow up data is lacking. We investigated whether NAFLD, as determined by the fatty liver index (FLI), could predict incident CKD in 10-year prospective cohort study. We also assessed the clinical utility of FLI to predict the development of CKD. METHODS: 6,238 adults aged 40 to 69 years without baseline CKD from the Ansan-Ansung cohort were examined...
2017: PloS One
https://www.readbyqxmd.com/read/28737713/quality-assessment-of-gentiana-rigescens-from-different-geographical-origins-using-ft-ir-spectroscopy-combined-with-hplc
#10
Zhe Wu, Yanli Zhao, Ji Zhang, Yuanzhong Wang
Gentiana rigescens is a precious herbal medicine in China because of its liver-protective and choleretic effects. A method for the qualitative identification and quantitative evaluation of G. rigescens from Yunnan Province, China, has been developed employing Fourier transform infrared (FT-IR) spectroscopy and high performance liquid chromatography (HPLC) with the aid of chemometrics such as partial least squares discriminant analysis (PLS-DA) and support vector machines (SVM) regression. Our results indicated that PLS-DA model could efficiently discriminate G...
July 24, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28737573/investigating-the-impact-of-different-suspicion-of-infection-criteria-on-the-accuracy-of-quick-sepsis-related-organ-failure-assessment-systemic-inflammatory-response-syndrome-and-early-warning-scores
#11
Matthew M Churpek, Ashley Snyder, Sarah Sokol, Natasha N Pettit, Dana P Edelson
OBJECTIVE: Studies in sepsis are limited by heterogeneity regarding what constitutes suspicion of infection. We sought to compare potential suspicion criteria using antibiotic and culture order combinations in terms of patient characteristics and outcomes. We further sought to determine the impact of differing criteria on the accuracy of sepsis screening tools and early warning scores. DESIGN: Observational cohort study. SETTING: Academic center from November 2008 to January 2016...
July 21, 2017: Critical Care Medicine
https://www.readbyqxmd.com/read/28737551/vibrotactile-thresholds-on-the-mastoid-and-forehead-position-of-deaf-patients-using-radioear-b71-and-b81
#12
Karl-Johan Fredén Jansson, Bo Håkansson, Sabine Reinfeldt, Laura Fröhlich, Torsten Rahne
OBJECTIVES: The main objective of this study was to measure the vibrotactile thresholds on the mastoid process and forehead positions using patients with bilateral deafness and to compare the results from the two bone conduction vibrators Radioear B71 and B81. DESIGN: There is a possibility that the vibrotactile sensation on the skin makes it difficult to discriminate between sound and vibration. The risk is highest for patients who have bone conduction hearing thresholds in proximity to or worse than their vibrotactile thresholds...
July 21, 2017: Ear and Hearing
https://www.readbyqxmd.com/read/28737503/directional-connectivity-in-the-eeg-is-able-to-discriminate-wakefulness-from-nrem-sleep
#13
Giulia Lioi, Steven L Bell, David C Smith, David M Simpson
A reliable measure of consciousness is of great interest for various clinical applications including sleep studies and the assessment of depth of anaesthesia. A number of measures of consciousness based on the EEG have been proposed in the literature and tested in studies of dreamless sleep, general anaesthesia and disorders of consciousness. However, reliability has remained a persistent challenge. Despite considerable theoretical and experimental effort, the neural mechanisms underlying consciousness remain unclear, but connectivity between brain regions is thought to be disrupted, impairing information flow...
July 24, 2017: Physiological Measurement
https://www.readbyqxmd.com/read/28737407/label-free-monitoring-of-single-molecule-immunoreaction-with-a-nanopipette
#14
Ru-Jia Yu, Yi-Lun Ying, Yong-Xu Hu, Rui Gao, Yi-Tao Long
The nanopipette has been employed for the single molecule analysis due to its advantage of easy fabrication and controllable diameter. Herein, we present that the single molecule immunoreaction could be monitored by using the quartz nanopipette through the discrimination of characteristic blockade current, which reflect the intrinsic character of the individual unlabeled protein molecules due to its heterogenous motion in solution. Our methods show the ability to monitor the immunoreaction between single α-fetal protein (AFP) and its specific antibody in aqueous solution without any labelling...
July 24, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28737289/comparison-of-pasl-pcasl-and-background-suppressed-3d-pcasl-in-mild-cognitive-impairment
#15
Sudipto Dolui, Marta Vidorreta, Ze Wang, Ilya M Nasrallah, Abass Alavi, David A Wolk, John A Detre
We compared three implementations of single-shot arterial spin labeled (ASL) perfusion magnetic resonance imaging: two-dimensional (2D) pulsed ASL (PASL), 2D pseudocontinuous ASL (PCASL), and background-suppressed (BS) 3D PCASL obtained in a cohort of patients with mild cognitive impairment (MCI) and elderly controls. Study subjects also underwent (18) F-fluorodeoxyglucose positron emission tomography ((18) F-FDG PET). While BS 3D PCASL showed the lowest (P < 0.001) gray matter-white matter cerebral blood flow (CBF) contrast ratio, it provided the highest (P < 0...
July 24, 2017: Human Brain Mapping
https://www.readbyqxmd.com/read/28737282/discrimination-gender-and-self-reported-aesthetic-problems-among-brazilian-adults
#16
Alexandre Baumgarten, João Luiz Bastos, Ramona Fernanda Ceriotti Toassi, Juliana Balbinot Hilgert, Fernando Neves Hugo, Roger Keller Celeste
OBJECTIVES: To explore factors associated with discrimination in healthcare services and to assess whether discrimination based on dental aesthetics differs by sex. METHODS: Cross-sectional analysis based on a household survey carried out in a city in Southern Brazil. Fifteen primary health care (PHC) units with a dental team were randomly selected, and individuals who used the public services in the catchment areas of the PHC units were interviewed. The survey questionnaire included experiences with discrimination related to health services, sociodemographic and dental characteristics...
July 24, 2017: Community Dentistry and Oral Epidemiology
https://www.readbyqxmd.com/read/28737267/appearance-and-characterization-of-fruit-image-textures-for-quality-sorting-using-wavelet-transform-and-genetic-algorithms
#17
Suchitra Khoje
Images of four qualities of Mangoes and Guavas are evaluated for colour and textural features to characterize and classify them, and to model the fruit appearance grading. The paper discusses three approaches to identify most discriminating texture features of both the fruits. In the first approach, fruit's colour and texture features are selected using Mahalanobis distance. A total of 20 colour features and 40 textural features are extracted for analysis. Using Mahalanobis distance and feature inter-correlation analyses, one best colour features [mean of a* (L*a*b* colour space) and two textural features [energy a*, contrast of H*]are selected as features for guava while two best colour features [R std, H std] and one textural features [energy b*]are selected as features for Mangoes with the highest discriminate power...
July 24, 2017: Journal of Texture Studies
https://www.readbyqxmd.com/read/28737111/habit-in-personality-and-social-psychology
#18
Wendy Wood
Habits are largely absent from modern social and personality psychology. This is due to outdated perspectives that placed habits in conflict with goals. In modern theorizing, habits are represented in memory as implicit context-response associations, and they guide responding in conjunction with goals. Habits thus have important implications for our field. Emerging research shows that habits are an important mechanism by which people self-regulate and achieve long-term goals. Also, habits change through specific interventions, such as changes in context cues...
July 1, 2017: Personality and Social Psychology Review
https://www.readbyqxmd.com/read/28736977/use-of-microbial-indicators-combined-with-environmental-factors-coupled-to-metrology-tools-for-discrimination-and-classification-of-luzhou-flavored-pit-muds
#19
Q Y Zhang, Y J Yuan, Z M Liao, W X Zhang
AIMS: Pit mud is essential for the quality and yield of Chinese Luzhou-flavored liquor. A reliable and fast method based on the use of microbial indicators combined with environmental factors coupled to metrology tools is needed to discriminate and classify different maturity levels of Luzhou-flavored pit muds. METHODS AND RESULTS: Firmicutes, Bacteroidetes, Actinobacteria, Lactobacillus, Bacillus, Methanosarcina, Methanocorpusculum, Methanoculleus and Clostridium kluyveri were microbial indicators in Luzhou-flavored pit muds...
July 23, 2017: Journal of Applied Microbiology
https://www.readbyqxmd.com/read/28736686/evaluating-changes-in-ocular-redness-using-a-novel-automated-method
#20
Francisco Amparo, Jia Yin, Antonio Di Zazzo, Tulio Abud, Ula V Jurkunas, Pedram Hamrah, Reza Dana
PURPOSE: To evaluate interobserver concordance in measured ocular redness among a group of raters using an objective computer-assisted method (ocular redness index [ORI]) and a group of clinicians using an ordinal comparative scale. METHODS: We conducted a prospective study to evaluate ocular redness in clinical photographs of 12 patients undergoing pterygium surgery. Photographs were acquired preoperatively, and at 1 week and 1 month postoperatively. One group of clinicians graded conjunctival redness in the photographs using an image-based comparative scale...
July 2017: Translational Vision Science & Technology
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