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Biventricular Pacing

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https://www.readbyqxmd.com/read/28219773/acute-effects-of-multi-site-biventricular-pacing-are-two-leads-really-better-than-one
#1
EDITORIAL
Ali Mehdirad, Charles Love
No abstract text is available yet for this article.
February 17, 2017: Journal of Cardiac Failure
https://www.readbyqxmd.com/read/28185354/eligibility-of-pacemaker-patients-for-subcutaneous-implantable-cardioverter-defibrillators
#2
James E Ip, Michael S Wu, Peter J Kennel, George Thomas, Christopher F Liu, Jim W Cheung, Steven M Markowitz, Bruce B Lerman
INTRODUCTION: The subcutaneous implantable cardioverter defibrillator (ICD) has emerged as a viable therapeutic option for patients who are deemed high risk for sudden cardiac death. Previous studies have shown that 7-15% of patients are not candidates for the S-ICD based on their intrinsic QRS/T-wave morphology. Presently, it is not known if the S-ICD can be considered as supplementary therapy in patients who are ventricularly paced. We sought to determine the proportion of ventricularly paced patients who would qualify for an S-ICD...
February 10, 2017: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/28161770/posterior-ventricular-restoration-treatment-for-heart-failure-a-review-past-present-and-future-aspects
#3
REVIEW
Tadashi Isomura, Yasuhisa Fukada, Takuya Miyazaki, Minoru Yoshida, Akimasa Morisaki, Masahiro Endo
Congestive heart failure (CHF) is one of the major causes of death and occurs in more than 15,000,000 patients worldwide. The incidence is expected to increase in parallel with the aging population. Most current therapies for CHF are medications, and biventricular pacing implantation as appropriated by cardiologists, or surgical interventions. The heart transplantation for indicated patients is still gold standard surgery although the 10-year survival rate is approximately 60% based on the worldwide data. However, the cardiac transplantation remains epidemiologically insignificant because of donor pool limitations...
February 4, 2017: General Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28131806/-effects-of-prolonged-endocardial-stimulation-on-left-ventricular-mechanical-synchrony-a-pilot-study-applying-gated-spect-phase-analysis-endocardial-stimulation-and-dyssynchrony
#4
Federico Ferrando-Castagnetto, Roberto Ricca-Mallada, Alejandro Vidal, Rodolfo Ferrando
OBJETIVE: To evaluate left ventricular mechanical dyssynchrony (LVMD) associated to prolonged right ventricular pacing through an innovative imaging technique, as a pilot study in Uruguay. METHODS: We performed 99mTc-MIBI gated-SPECT and phase analysis in 12 patients with pacemakers implanted at least one year before scintigraphy due to advanced atrioventricular block. Clinical data, QRS duration, rate, mode and site of pacing in right ventricle, chamber diameters, presence and extension of myocardial scar and ischemia and rest LVEF were recorded...
January 25, 2017: Archivos de Cardiología de México
https://www.readbyqxmd.com/read/28126497/acute-effects-of-multisite-biventricular-pacing-on-dyssynchrony-and-hemodynamics-in-canines-with-heart-failure
#5
Qiong Qiu, Li Yang, Jing-Ting Mai, Ying Yang, Yong Xie, Yang-Xin Chen, Jing-Feng Wang
BACKGROUND: Multisite biventricular pacing(MSP) has been proposed as an alternative strategy to improve the efficiency of conventional biventricular pacing(BVP), but its utility remains unclear. This study sought to investigate whether MSP induced better synchrony and hemodynamic effects in canines with heart failure. METHODS AND RESULTS: After 3 weeks' rapid right ventricular pacing(RVP), 7 canines were sutured with 4 left ventricular(LV) leads on anterior, lateral, posterior and apical wall, and followed by MSP and BVP...
January 23, 2017: Journal of Cardiac Failure
https://www.readbyqxmd.com/read/28113292/non-invasive-personalisation-of-a-cardiac-electrophysiology-model-from-body-surface-potential-mapping
#6
Sophie Giffard-Roisin, Thomas Jackson, Lauren Fovargue, Jack Lee, Herve Delingette, Reza Razavi, Nicholas Ayache, Maxime Sermesant
Modelling cardiac electrophysiology (EP) can help understand pathologies and predict the response to therapies. Moreover, estimating patient-specific parameters of the EP model is crucial to obtain personalised information. The novelty of this paper is to use non-invasive data (body surface potential mapping, BSPM) in order to personalise the main parameters of a cardiac EP model for predicting different pacing conditions. First, an efficient forward model is proposed, coupling the Mitchell- Schaeffer transmembrane potential model with a current dipole formulation...
November 16, 2016: IEEE Transactions on Bio-medical Engineering
https://www.readbyqxmd.com/read/28088306/ventricular-fibrillation-occurring-after-atrioventricular-node-ablation-despite-minimal-difference-between-pre-and-post-ablation-heart-rates
#7
F Squara, G Theodore, D Scarlatti, E Ferrari
We report the case of an 82-year-old man presenting with ventricular fibrillation (VF) occurring acutely after atrioventricular node (AVN) ablation. This patient had severe valvular cardiomyopathy, chronic atrial fibrillation (AF), and underwent prior to the AVN ablation a biventricular implantable cardiac defibrillator positioning. The VF was successfully cardioverted with one external electrical shock. What makes this presentation original is that the pre-ablation spontaneous heart rate in AF was slow (84 bpm), and that VF occurred after ablation despite a minimal heart rate drop of only 14 bpm...
February 2017: Annales de Cardiologie et D'angéiologie
https://www.readbyqxmd.com/read/28066827/optimized-left-ventricular-endocardial-stimulation%C3%A2-is-superior-to-optimized-epicardial%C3%A2-stimulation-in-ischemic-patients-with%C3%A2-poor-response-to-cardiac-resynchronization%C3%A2-therapy-a%C3%A2-combined-magnetic-resonance-imaging-electroanatomic%C3%A2-contact-mapping-and-hemodynamic
#8
Jonathan M Behar, Tom Jackson, Eoin Hyde, Simon Claridge, Jaswinder Gill, Julian Bostock, Manav Sohal, Bradley Porter, Mark O'Neill, Reza Razavi, Steve Niederer, Christopher Aldo Rinaldi
OBJECTIVES: The purpose of this study was to identify the optimal pacing site for the left ventricular (LV) lead in ischemic patients with poor response to cardiac resynchronization therapy (CRT). BACKGROUND: LV endocardial pacing may offer benefit over conventional CRT in ischemic patients. METHODS: We performed cardiac magnetic resonance, invasive electroanatomic mapping (EAM), and measured the acute hemodynamic response (AHR) in patients with existing CRT systems...
December 2016: JACC. Clinical Electrophysiology
https://www.readbyqxmd.com/read/28041584/hemodynamics-of-his-bundle-pacing
#9
REVIEW
Luca Alberti, Paolo Pieragnoli, Giuseppe Ricciardi, Luigi Padeletti
This review will focus on the feasibility of long term His bundle pacing and its effects on left ventricle (LV) hemodynamics. Compared with right ventricular pacing, His bundle pacing results in a more physiological electro-mechanical activation that contributes to preserve LV function. Moreover some studies showed a similar effect to biventricular pacing in patients with heart failure and left bundle branch block. Recent observations indicate that His bundle pacing should be considered as an optimal site to pace right ventricle in patients who are candidates for cardiac resynchronization therapy...
January 2017: Journal of Electrocardiology
https://www.readbyqxmd.com/read/28032941/permanent-his-bundle-pacing-the-past-present-and-future
#10
REVIEW
Parikshit S Sharma, Kenneth A Ellenbogen, Richard G Trohman
Long-term right ventricular (RV) apical pacing has been associated with an increased risk of death, heart failure, and atrial fibrillation (AF). Alternative sites for RV pacing have not proven to be superior to RV apical pacing. Cardiac resynchronization therapy (CRT) using a biventricular (BiV) lead system is indicated for patients with a low left ventricular ejection fraction and QRS prolongation, but there remains about a 25-30% nonresponse rate. CRT has been less effective for nonleft bundle branch block conduction delay and with normal/low normal left ventricular function...
December 29, 2016: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/28025231/cardiac-resynchronization-therapy-by-multipoint-pacing-improves-response-of-left-ventricular-mechanics-and-fluid-dynamics-a-three-dimensional-and-particle-image-velocimetry-echo-study
#11
Mariachiara Siciliano, Federico Migliore, Luigi Badano, Emanuele Bertaglia, Gianni Pedrizzetti, Stefano Cavedon, Alessandro Zorzi, Domenico Corrado, Sabino Iliceto, Denisa Muraru
AIMS: To characterize the effect of multipoint pacing (MPP) compared to biventricular pacing (BiV) on left ventricle (LV) mechanics and intraventricular fluid dynamics by three-dimensional echocardiography (3DE) and echocardiographic particle imaging velocimetry (Echo-PIV). METHODS AND RESULTS: In 11 consecutive patients [8 men; median age 65 years (57-75)] receiving cardiac resynchronization therapy (CRT) with a quadripolar LV lead (Quartet,St.Jude Medical,Inc...
December 26, 2016: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28011838/analysis-of-lead-placement-optimization-metrics-in-cardiac-resynchronization-therapy-with-computational-modelling
#12
Andrew Crozier, Bojan Blazevic, Pablo Lamata, Gernot Plank, Matthew Ginks, Simon Duckett, Manav Sohal, Anoop Shetty, Christopher A Rinaldi, Reza Razavi, Steven A Niederer, Nicolas P Smith
AIMS: The efficacy of cardiac resynchronization therapy (CRT) is known to vary considerably with pacing location, however the most effective set of metrics by which to select the optimal pacing site is not yet well understood. Computational modelling offers a powerful methodology to comprehensively test the effect of pacing location in silico and investigate how to best optimize therapy using clinically available metrics for the individual patient. METHODS AND RESULTS: Personalized computational models of cardiac electromechanics were used to perform an in silico left ventricle (LV) pacing site optimization study as part of biventricular CRT in three patient cases...
December 2016: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28011837/non-invasive-model-based-measures-of-ventricular-electrical-dyssynchrony-for-predicting-crt-outcomes
#13
Christopher T Villongco, David E Krummen, Jeffrey H Omens, Andrew D McCulloch
AIMS: Left ventricular activation delay due to left bundle branch block (LBBB) is an important determinant of the severity of dyssynchronous heart failure (DHF). We investigated whether patient-specific computational models constructed from non-invasive measurements can provide measures of baseline dyssynchrony and its reduction after CRT that may explain the degree of long-term reverse ventricular remodelling. METHODS AND RESULTS: LV end-systolic volume reduction (ΔESVLV) measured by 2D trans-thoracic echocardiography in eight patients following 6 months of CRT was significantly (P < 0...
December 2016: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28011836/new-insights-from-a-computational-model-on-the-relation-between-pacing-site-and-crt-response
#14
Marieke Pluijmert, Peter H M Bovendeerd, Joost Lumens, Kevin Vernooy, Frits W Prinzen, T Delhaas
AIMS: Cardiac resynchronization therapy (CRT) produces clinical benefits in chronic heart failure patients with left bundle-branch block (LBBB). The position of the pacing site on the left ventricle (LV) is considered an important determinant of CRT response, but the mechanism how the LV pacing site determines CRT response is not completely understood. The objective of this study is to investigate the relation between LV pacing site during biventricular (BiV) pacing and cardiac function...
December 2016: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28000309/utilization-of-permanent-his-bundle-pacing-for-management-of-pro-arrhythmia-related-to-bi-ventricular-pacing
#15
Aamir Sofi, Pugazhendhi Vijayaraman, S Serge Barold, Bengt Herweg
Biventricular pacing has occasionally been associated with ventricular pro-arrhythmia which at times can be refractory to conventional antiarrhythmic drug therapy and ablative intervention. Recently, permanent His bundle pacing has emerged as a reasonable alternative to right ventricular and biventricular pacing. In addition, by maintaining the physiologic pattern of ventricular electrical activation it is less likely to be arrhythmogenic. We here report the use of permanent His-bundle pacing to manage ventricular pro-arrhythmia that developed after initiation of biventricular pacing and was unresponsive to antiarrhythmic and ablative therapy...
December 20, 2016: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/27989870/time-course-of-electrical-remodelling-of-native-conduction-after-cardiac-resynchronization-therapy-and-its-impact-on-clinical-outcome
#16
Marta Cvijić, David Žižek, Bor Antolič, Igor Zupan
BACKGROUND: Cardiac resynchronization therapy (CRT) induces structural and electrical remodelling (ER) in heart failure (HF) patients. Our aim was to assess time course of ER of native conduction and mechanical remodelling after CRT and impact of CRT-induced ER on clinical outcome. METHODS AND RESULTS: We prospectively included 62 patients (aged 66±10 years). Echocardiographic and ECG parameters were measured at baseline, 1, 3, 6, 9, and 12 months after implantation...
October 28, 2016: Journal of Cardiac Failure
https://www.readbyqxmd.com/read/27958262/role-of-low%C3%A2-dose-dobutamine-echocardiography-in-predicting-response-to-biventricular-pacing-results-from-the%C3%A2-multicenter-viability-in-cardiac-resynchronisation-therapy-viacrt-study
#17
Edyta Płońska-Gościniak, Jarosław D Kasprzak, Tomasz Kukulski, Katarzyna Mizia-Stec, Ewa Nowalany-Kozielska, Zbigniew Gąsior, Krystian Wita, Władysław Sinkiewicz, Hanna Szwed, Piotr Gościniak, Łukasz Chrzanowski
INTRODUCTION    The response to Cardiac Resynchronisation Therapy (CRT) varies significantly, resulting in lack of improvement among the substantial patients proportion.  OBJECTIVES    To identify mechanical dyssynchrony indices with combination of myocardial viability characteristics for predicting long-term response to CRT.  PATIENTS AND METHODS    ViaCRT was a multicentre study coordinated by the Working Group on Echocardiography of  Polish Cardiac Society. 127 patients with heart failure were assessed prospectively...
December 12, 2016: Polskie Archiwum Medycyny Wewnętrznej
https://www.readbyqxmd.com/read/27920838/successful-resynchronization-by-permanent-his-bundle-pacing-in-a-patient-with-pacing-induced-cardiomyopathy
#18
Yoji Iida, Tomoaki Izawa, Chikara Kobari, Toru Yatsuhashi, Nobuyuki Makishima
Right ventricular (RV) pacing has been reported to result in ventricular dyssynchrony, heart failure, and increased mortality. Pacing associated deterioration of left ventricular (LV) systolic function has been termed pacing-induced cardiomyopathy (PICM). While upgrading to biventricular pacing (BiVP) is an effective therapy for PICM, permanent His-bundle pacing (HBP) can be a physiological alternative to BiVP. We present a patient with PICM who responded dramatically to permanent HBP.
December 2016: Journal of Arrhythmia
https://www.readbyqxmd.com/read/27908173/pacemaker-and-icd-oversensing-induced-by-movements-near-the-mri-scanner-bore
#19
E Mattei, F Censi, G Calcagnini, R Falsaperla, E Genovese, A Napolitano, V Cannatà
PURPOSE: The effect of the movement near the MRI scanner bore for people with a pacemaker (PM) or an implantable cardioverter defibrillator (ICD) is experimentally evaluated and discussed. METHODS: The authors performed in vitro measurements on a saline-filled human-shaped phantom (male, 170 cm height), equipped first with an MR-conditional PM (bicameral configuration, DDD programming), then with an MR-conditional ICD (biventricular configuration, detection algorithms enable but shock delivery disable)...
December 2016: Medical Physics
https://www.readbyqxmd.com/read/27886925/the-role-of-atrioventricular-and-interventricular-optimization-for-cardiac-resynchronization-therapy
#20
REVIEW
Daniel B Cobb, Michael R Gold
Many patients with left ventricular systolic dysfunction may benefit from cardiac resynchronization therapy; however, approximately 30% of patients do not experience significant clinical improvement with this treatment. AV and VV delay optimization techniques have included echocardiography, device-based algorithms, and several other novel noninvasive techniques. Using these techniques to optimize device settings has been shown to improve hemodynamic function acutely; however, the long-term clinical benefit is limited...
January 2017: Heart Failure Clinics
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