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https://www.readbyqxmd.com/read/28241354/effect-of-fibrinogen-concentrate-on-intraoperative-blood-loss-among-patients-with-intraoperative-bleeding-during-high-risk-cardiac-surgery-a-randomized-clinical-trial
#1
Süleyman Bilecen, Joris A H de Groot, Cor J Kalkman, Alexander J Spanjersberg, George J Brandon Bravo Bruinsma, Karel G M Moons, Arno P Nierich
Importance: Fibrinogen concentrate might partly restore coagulation defects and reduce intraoperative bleeding. Objective: To determine whether fibrinogen concentrate infusion dosed to achieve a plasma fibrinogen level of 2.5 g/L in high-risk cardiac surgery patients with intraoperative bleeding reduces intraoperative blood loss. Design, Setting, and Participants: A randomized, placebo-controlled, double-blind clinical trial conducted in Isala Zwolle, the Netherlands (February 2011-January 2015), involving patients undergoing elective, high-risk cardiac surgery (ie, combined coronary artery bypass graft [CABG] surgery and valve repair or replacement surgery, the replacement of multiple valves, aortic root reconstruction, or reconstruction of the ascending aorta or aortic arch) with intraoperative bleeding (blood volume between 60 and 250 mL suctioned from the thoracic cavity in a period of 5 minutes) were randomized to receive either fibrinogen concentrate or placebo...
February 21, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/28241228/use-of-spreader-flaps-without-dorsal-hump-reduction-and-the-effect-on-nasal-function
#2
Justin C Sowder, Andrew J Thomas, Cristian D Gonzalez, Nikhil S Limaye, Preston Daniel Ward
Importance: Internal nasal valve (INV) collapse is a common cause of nasal obstruction, and spreader grafts are the established standard of treatment. Recently, spreader flaps have gained attention in the treatment of nasal valve stenosis when performed in conjunction with dorsal hump reduction. To date, the efficacy of the spreader flap technique without dorsal hump reduction has not been previously described. Objective: To determine whether spreader flaps are equivalent to spreader grafts in correcting INV collapse in the absence of simultaneous dorsal hump reduction...
February 23, 2017: JAMA Facial Plastic Surgery
https://www.readbyqxmd.com/read/28240727/under-pressure-the-utility-of-spacers-in-univalved-fiberglass-casts
#3
Kevin Kleis, John A Schlechter, Joshua D Doan, Christine L Farnsworth, Eric W Edmonds
BACKGROUND: Univalving fiberglass casts after fracture manipulation or extremity surgery reduces the risk of developing compartment syndrome (CS). Previous experiments have demonstrated that univalving decreases intracompartmental pressures (ICPs), but increases the risk for loss of fracture reduction due to altering the mechanical properties of the cast. The purpose of this study was to correlate cast valve width within a univalved cast model to decreasing ICP. METHODS: Saline bags (1 L) were covered with stockinette, Webril, and fiberglass tape then connected to an arterial pressure line monitor...
February 24, 2017: Journal of Pediatric Orthopedics
https://www.readbyqxmd.com/read/28240641/transcatheter-mitral-valve-replacement-with-a-novel-self-expandable-prosthesis-single-institutional-experience-procedural-outcomes-and-follow-up
#4
Gian Paolo Ussia, Valeria Cammalleri, Jawahar L Mehta, Kunal Sarkar, Saverio Muscoli, Pasquale de Vico, Giovanni Ruvolo, Francesco Romeo
AIMS: We report our experience with the CardiAQ prosthetic valve using both transapical and transseptal access. Aim of our study was proving the feasibility, safety and effectiveness of a novel transcatheter mitral valve bioprosthesis. METHODS: Four patients with severe mitral regurgitation, not eligible for mitral valve surgery, were treated with the CardiAQ valve. The procedures were performed under general anaesthesia, fluoroscopic and transesophageal echocardiographic guidance...
February 24, 2017: Journal of Cardiovascular Medicine
https://www.readbyqxmd.com/read/28240599/multiferroic-properties-of-the-pbtio-sub-3-sub-la-sub-2-3-sub-sr-sub-1-3-sub-mno-sub-3-sub-interface-studied-from-first-principles
#5
Vladislav Borisov, Sergey Ostanin, Ingrid Mertig
Magnetoelectric coupling and spin polarization at the multiferroic PbTiO<sub>3</sub>/La<sub>2/3</sub>Sr<sub>1/3</sub>MnO<sub>3</sub> (PTO/LSMO) interface is studied from first principles in view of the recent experimental observation of the tunneling magnetoresistance sign inversion in Co/PZT/LSMO tunnel junctions (D. Pantel <i>et al.</i>, Nat. Mater. <b>11</b>, 289 (2012)). Our results confirm the stabilization of the locally antiferromagnetic order in the manganite when the PTO polarization points away from the LSMO side, which changes the interface magnetization by 6...
February 27, 2017: Journal of Physics. Condensed Matter: An Institute of Physics Journal
https://www.readbyqxmd.com/read/28240518/the-challenge-of-preoperative-quantification-of-functional-tricuspid-regurgitation-and-of-right-ventricle-function-what-information-is-clinically-relevant
#6
Rebecca T Hahn
Functional or secondary tricuspid regurgitation (TR) is the most common etiology of severe TR in the western world. The presence of functional TR, either isolated or in combination with left heart disease is associated with unfavorable natural history however surgical mortality for isolated tricuspid valve interventions remain higher than for any other single valve surgery. Determining the severity of TR remains a controversial area and will continue to evolve as new techniques for assessing this valve as well as the right ventricle, are investigated...
February 27, 2017: Minerva Cardioangiologica
https://www.readbyqxmd.com/read/28240433/use-of-three-dimensional-transesophageal-echocardiography-to-evaluate-mitral-valve-morphology-for-risk-stratification-prior-to-mitral-valvuloplasty
#7
Loren Francis, Alan Finley, Walead Hessami
: Mitral stenosis is often managed percutaneously with an interventional procedure such as balloon commissurotomy. Although this often results in an increased mitral valve area and improved clinical symptoms, this procedure is not benign and may have serious complications including the development of hemodynamically significant mitral valve regurgitation. Multiple scoring systems have been developed to attempt to risk stratify these patients prior to their procedure. CASE: A 64-year-old patient underwent an emergent mitral valve replacement after having percutaneous mitral balloon commissurotomy complicated by development of severe mitral regurgitation...
February 2017: Echocardiography
https://www.readbyqxmd.com/read/28240431/usefulness-of-two-and-three-dimensional-transesophageal-echocardiography-in-the-assessment-of-proximal-left-coronary-system-compression-by-a-paraprosthetic-aortic-valve-abscess
#8
Amier Ahmad, Samuel K McElwee, Amy Z Jiang, Kirolos N Barssoum, Ahmed E Elkaryoni, Mohammed J Arisha, Swetha Srialluri, Frank Seghatol, Navin C Nanda
Paraprosthetic aortic valve abscess represents a rare, but lethal complication of infective endocarditis. We report a case of proximal left coronary system compression by a paraprosthetic aortic valve abscess whose detection was augmented using live/real time three-dimensional transesophageal echocardiography. Our case illustrates the usefulness of combined two- and three-dimensional transesophageal echocardiography in detecting this finding.
February 2017: Echocardiography
https://www.readbyqxmd.com/read/28240096/role-of-%C3%AE-2-microglobulin-in-postoperative-cognitive-decline
#9
Marta Załęska-Kocięcka, Paweł Jezierski, Maciej Grabowski, Krzysztof Kuśmierski, Maciej Dąbrowski, Katarzyna Piotrowska, Marek Banaszewski, Jacek Imiela, Janina Stępińska
AIM: β2-microglobulin (β2M) was proved to affect hippocampal functions in mice. MATERIALS & METHODS: Seventy-one patients undergoing aortic valve replacement were analyzed in prospective observational study. Kidney biomarkers and Mini Mental State Examinations (MMSEs) were performed before procedure, at discharge and after 6 months. RESULTS: Patients with β2M increase over the median change (>0.42 mg/l) experienced a significant in-hospital drop in MMSE (p = 0...
March 2017: Biomarkers in Medicine
https://www.readbyqxmd.com/read/28239994/aortic-stenosis-in-dialysis-patients
#10
REVIEW
Yousif Ahmad, Michael F Bellamy, Christopher S R Baker
Aortic valve stenosis occurs 10-20 years earlier in patients on dialysis compared with the general population. This is likely related to the exposure of the valve to a milieu that predisposes to calcification as well as increased shear stress across the valve. Objective assessment of stenosis severity is largely made using echocardiography though accurate interpretation requires an understanding of the potential pitfalls of the technique and the influence of cardiac output upon the gradient measured across the valve...
February 26, 2017: Seminars in Dialysis
https://www.readbyqxmd.com/read/28239938/lipomatosis-of-the-ileocaecal-valve-an-unusual-cause-of-small-bowel-obstruction
#11
Jiahua Huang, Raymond Yap, Neil Lambie, Francis F Lam
No abstract text is available yet for this article.
February 27, 2017: ANZ Journal of Surgery
https://www.readbyqxmd.com/read/28239757/predictive-factor-of-secondary-tricuspid-regurgitation-after-aortic-valve-replacement-for-aortic-stenosis-the-importance-of-myocardial-hypertrophy-and-diastolic-dysfunction
#12
Takashi Igarashi, Masahiro Tanji, Koki Takahashi, Keiichi Ishida, Satomi Sasaki, Hitoshi Yokoyama
OBJECTIVES: The aim of this study is to determine the predictors of secondary tricuspid regurgitation after aortic valve replacement for aortic stenosis. METHODS: Seventy-one patients, who underwent aortic valve replacement for aortic stenosis at our institute from January 2006 to July 2011, were divided into two groups: an STR group, which included 15 patients with moderate or greater than moderate secondary tricuspid regurgitation at a follow-up visit and a control group...
February 26, 2017: General Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28239201/immersogeometric-cardiovascular-fluid-structure-interaction-analysis-with-divergence-conforming-b-splines
#13
David Kamensky, Ming-Chen Hsu, Yue Yu, John A Evans, Michael S Sacks, Thomas J R Hughes
This paper uses a divergence-conforming B-spline fluid discretization to address the long-standing issue of poor mass conservation in immersed methods for computational fluid-structure interaction (FSI) that represent the influence of the structure as a forcing term in the fluid subproblem. We focus, in particular, on the immersogeometric method developed in our earlier work, analyze its convergence for linear model problems, then apply it to FSI analysis of heart valves, using divergence-conforming B-splines to discretize the fluid subproblem...
February 1, 2017: Computer Methods in Applied Mechanics and Engineering
https://www.readbyqxmd.com/read/28238646/transcatheter-aortic-valve-implantation-in-patients-with-previous-mitral-prostheses
#14
Ignacio J Amat-Santos, Carlos Cortés, Javier Castrodeza, Javier Tobar, Paol Rojas, José A San Román
No abstract text is available yet for this article.
February 23, 2017: Revista Española de Cardiología
https://www.readbyqxmd.com/read/28238508/using-a-multidimensional-prognostic-index-mpi-based-on-comprehensive-geriatric-assessment-cga-to-predict-mortality-in-elderly-undergoing-transcatheter-aortic-valve-implantation
#15
Marie-Laure Bureau, Evelyne Liuu, Luc Christiaens, Alberto Pilotto, Jean Mergy, Fabienne Bellarbre, Pierre Ingrand, Marc Paccalin
BACKGROUND: Selection of appropriate elderly who can benefit from transcatheter aortic valve implantation (TAVI) is challenging. We evaluated the prognosis of this procedure according to the comprehensive geriatric assessment (CGA) based on the multidimensional prognostic index (MPI). METHODS: Prospective observational monocentric study from January 2013 to December 2015. Consecutive patients aged ≥75 who underwent TAVI and a complete CGA were included. Baseline demographic, geriatric and cardiologic data were collected...
February 16, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28238252/recommendations-for-valve-replacement-in-ischemic-mitral-regurgitation-with-compromised-ventricle
#16
Kerem M Vural
The unique features of ischemic mitral regurgitation may necessitate attention to certain points during mitral valve replacement (MVR). A few simple but practical recommendations are offered for concomitant or isolated MVR in this high-risk population which is often burdened by an extremely limited myocardial reserve.
September 2016: Journal of Heart Valve Disease
https://www.readbyqxmd.com/read/28238251/percutaneous-pulmonary-valve-implantation-in-the-patched-right-ventricular-outflow-tract-51-years-after-surgical-repair-for-tetralogy-of-fallot
#17
Sebastian Grundmann, René Hoehn, Johannes Kroll, Jochen Grohmann
Percutaneous pulmonary valve implantation (PPVI) has become a widely practiced treatment option for patients with right ventricular outflow tract (RVOT) dysfunction. For this procedure, the Melody transcatheter pulmonary valve has become the most widely used system. On-label indications are limited to the treatment of failing circumferential conduits. However, there is growing but still limited experience with the off-label treatment of native or patched RVOTs. Here, the case is reported of a 57-year-old patient in whom redo-surgery for a dysfunctional pulmonary valve could be avoided by PPVI into the patched RVOT at 51 years after tetralogy of Fallot repair...
September 2016: Journal of Heart Valve Disease
https://www.readbyqxmd.com/read/28238250/atrial-septostomy-as-a-bridge-to-replace-a-thrombosed-mechanical-aortic-valve-requiring-extracorporeal-membrane-oxygenation
#18
Adarsh Katamreddy, David F Snipelisky, Mackram F Eleid
Atrial septostomy is an infrequently used percutaneous technique to decompress either side of the heart. Here, a case is reported of atrial septostomy performed as an emergency 'bridge' procedure in a hemodynamically unstable 62-year-old man with acute mechanical prosthetic aortic valve thrombosis requiring peripheral venoarterial (VA) extracorporeal membrane oxygenation (ECMO). ECMO was placed emergently as the patient suffered cardiac arrest during anesthesia induction for surgical replacement of the thrombosed prosthetic aortic valve...
September 2016: Journal of Heart Valve Disease
https://www.readbyqxmd.com/read/28238249/aortic-valve-replacement-in-dextrocardia-and-anomalous-origin-of-the-coronary-artery
#19
Takanori Kono, Toru Takaseya, Takahiro Shojima, Kazuyoshi Takagi, Koji Akasu, Hiroyuki Tanaka
Situs inversus totalis and anomalous origin of the left coronary artery are rare conditions. An 87-year-old woman with both conditions presented to the authors' hospital with symptomatic aortic stenosis. She underwent aortic valve replacement (AVR) and coronary artery bypass grafting (CABG; saphenous vein graft to the left main trunk). The operator mainly stood on the left side of the patient and performed surgery without difficulty. Both, AVR and CABG were successfully performed despite these two rare conditions...
September 2016: Journal of Heart Valve Disease
https://www.readbyqxmd.com/read/28238248/a-simple-technique-for-aortic-root-dissection-and-massive-aortic-regurgitation-repair-after-blunt-chest-trauma
#20
Javier Gualis, Mario Castaño, Jose Manuel Martínez-Comendador, Carmen Garrote, Javier Otero, Elio Martín, Pascuale Maiorano, Jose Miguel Marcos, Rodrigo Estevez-Loureiro
Aortic regurgitation due to valve injury after blunt chest trauma is a rare condition that may be caused by leaflet or commissural rupture, aortic dissection, or a combination of both. The case is presented of a 48-year-old male patient with an aortic dissection and aortic valve commissural detachment and massive aortic regurgitation after a 12-meter vertical free fall and secondary thoracic blunt trauma. The aortic root tear and dissection was repaired with a continuous polypropylene 5/0 suture and subcommissural annuloplasty that restored the aortic valve geometry and resulted in a normally functioning aortic valve...
September 2016: Journal of Heart Valve Disease
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