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https://www.readbyqxmd.com/read/29679793/self-stigma-in-ptsd-prevalence-and-correlates
#1
Kelsey A Bonfils, Paul H Lysaker, Philip T Yanos, Alysia Siegel, Bethany L Leonhardt, Alison V James, Beth Brustuen, Brandi Luedtke, Louanne W Davis
Self-stigma is the internalization of negative societal stereotypes about those with mental illnesses. While self-stigma has been carefully characterized in severe mental disorders, like schizophrenia, the field has yet to examine the prevalence and correlates of self-stigma in post-traumatic stress disorder (PTSD). Thus, we assessed self-stigma in veterans diagnosed with PTSD and compared with veterans with schizophrenia. We further examined associations between PTSD, depressive symptoms and self-stigma in the PTSD sample...
April 3, 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29678073/a-decision-support-tool-for-healthcare-professionals-in-the-management-of-hyperphosphatemia-in-hemodialysis
#2
Sisse H Laursen, Amanda A Buus, Lisbet Brandi, Peter Vestergaard, Ole K Hejlesen
Hyperphosphatemia is known as one of the more challenging conditions in end-stage renal disease patients. This study set out to present and evaluate a healthcare-oriented decision support tool in the management of hyperphosphatemia within hemodialysis therapy. A prototype module was designed to fit into the interface of a modern dialysis machine (Fresenius 5008). The prototype included three main functions: 1) immediate bedside blood sample access, 2) a model based prognosis tool with estimates of P-phosphate and 3) an overview of the user's phosphate related activities during dialysis treatments...
2018: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/29677398/does-stress-increase-risk-of-breast-cancer-a-15-year-prospective-study
#3
Phyllis Butow, Melanie Price, Joseph Coll, Katherine Tucker, Bettina Meiser, Roger Milne, Judith Wilson, Louise Heiniger, Brandi Baylock, Tracey Bullen, Prue Weideman, Kelly-Anne Phillips
OBJECTIVE: The possible impact of stress on cancer incidence remains controversial. We prospectively evaluated associations between life event stressors, social support, personality characteristics (optimism, anger control, anti-emotionality) and risk of developing primary breast cancer (BCa), in women at increased familial risk of BCa. METHODS: A prospective cohort, repeated measures design was employed. Recruitment was through the Kathleen Cuningham Foundation Consortium for Research into Familial breast cancer (kConFab), which collects genetic, epidemiological and clinical data from Australasian families with multiple BCa cases...
April 20, 2018: Psycho-oncology
https://www.readbyqxmd.com/read/29674199/the-impact-of-female-fetal-sex-on-preeclampsia-and-the-maternal-immune-milieu
#4
Brandie D Taylor, Roberta B Ness, Mark A Klebanoff, Gong Tang, James M Roberts, David M Hougaard, Kristin Skogstrand, Catherine L Haggerty
OBJECTIVE: Small studies suggest that fetal sex alters maternal inflammation. We examined the association between fetal sex, preeclampsia and circulating maternal immune markers. METHODS: This was a secondary data analysis within a nested case-control study of 216 preeclamptic women and 432 randomly selected normotensive controls from the Collaborative Perinatal Project. All women had singleton, primiparous pregnancies without chronic health conditions. Logistic regression was used to calculate odds ratios (OR) and 95% confidence intervals (CI) for associations between female fetal sex and preeclampsia...
February 24, 2018: Pregnancy Hypertension
https://www.readbyqxmd.com/read/29672020/environmental-decontamination-of-a-chemical-warfare-simulant-utilizing-a-membrane-vesicle-encapsulated-phosphotriesterase
#5
Nathan J Alves, Martin H Moore, Brandy J Johnson, Scott Nathan Dean, Kendrick Bruce Turner, Igor L Medintz, Scott A Walper
While technologies for the remediation of chemical contaminants continue to emerge, growing interest in Green technologies has led researchers to explore natural catalytic mechanisms derived from microbial species. One such method, enzymatic degradation, offers an alternative to harsh chemical catalysts and resins. Recombinant enzymes, however, are often too labile or show limited activity when challenged with non-ideal environmental conditions that may vary in salinity, pH, or other physical properties. Here, we demonstrate how phosphotriesterase encapsulated in a bacterial outer membrane vesicle (OMV) can be used to degrade the organophosphate chemical warfare agent (CWA) simulant paraoxon in environmental water samples...
April 19, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29668514/the-role-of-nps-in-medication-assisted-treatment-for-opioid-use-disorder
#6
Brandi Parker Cotton, Ginette G Ferszt
No abstract text is available yet for this article.
May 17, 2018: Nurse Practitioner
https://www.readbyqxmd.com/read/29667744/intraurethral-erbium-yag-laser-for-the-management-of-urinary-symptoms-of-genitourinary-syndrome-of-menopause-a-pilot-study
#7
Adrian Gaspar, Sandra Maestri, Joaquin Silva, Hugo Brandi, Daniel Luque, Neža Koron, Zdenko Vižintin
OBJECTIVES: Genitourinary syndrome of menopause (GSM) combines the conditions of vulvovaginal atrophy (VVA) and urinary tract dysfunction, which is a result of urethral atrophy. There are several treatment methods available for the management of vulvovaginal symptoms of GSM, whereas urinary tract dysfunction often remains overlooked and undertreated. The objective of this pilot study was to assess the safety and efficacy of intraurethral Er:YAG laser treatment of urinary symptoms of GSM...
April 18, 2018: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/29667694/a-grounded-theory-investigation-into-sophomore-students-recall-of-depression-during-their-freshman-year-in-college-a-pilot-study
#8
Julie M Brandy, Theresa A Kessler, Christina H Grabarek
Using a grounded theory approach, the current descriptive qualitative design was conducted with sophomore students to understand the meaning participants gave their freshman experiences with depression. Twelve participants were recruited using scripted class announcements across campus. After informed consent, interviews began with the question: What was the experience of your freshman year in college? All interviews were completed with the primary investigator and transcribed verbatim. Interviews were analyzed using constant comparative methodology...
April 17, 2018: Journal of Psychosocial Nursing and Mental Health Services
https://www.readbyqxmd.com/read/29664924/evidence-supporting-a-role-for-astrocytes-in-the-regulation-of-cognitive-flexibility-and-neuronal-oscillations-through-the-ca2-binding-protein-s100%C3%AE
#9
Adam T Brockett, Gary A Kane, Patrick K Monari, Brandy A Briones, Pierre-Antoine Vigneron, Gabriela A Barber, Andres Bermudez, Uma Dieffenbach, Alexander D Kloth, Timothy J Buschman, Elizabeth Gould
The medial prefrontal cortex (mPFC) is important for cognitive flexibility, the ability to switch between two task-relevant dimensions. Changes in neuronal oscillations and alterations in the coupling across frequency ranges have been correlated with attention and cognitive flexibility. Here we show that astrocytes in the mPFC of adult male Sprague Dawley rats, participate in cognitive flexibility through the astrocyte-specific Ca2+ binding protein S100β, which improves cognitive flexibility and increases phase amplitude coupling between theta and gamma oscillations...
2018: PloS One
https://www.readbyqxmd.com/read/29661941/mental-health-of-transgender-and-gender-nonconforming-youth-compared-with-their-peers
#10
Tracy A Becerra-Culqui, Yuan Liu, Rebecca Nash, Lee Cromwell, W Dana Flanders, Darios Getahun, Shawn V Giammattei, Enid M Hunkeler, Timothy L Lash, Andrea Millman, Virginia P Quinn, Brandi Robinson, Douglas Roblin, David E Sandberg, Michael J Silverberg, Vin Tangpricha, Michael Goodman
BACKGROUND: Understanding the magnitude of mental health problems, particularly life-threatening ones, experienced by transgender and/or gender nonconforming (TGNC) youth can lead to improved management of these conditions. METHODS: Electronic medical records were used to identify a cohort of 588 transfeminine and 745 transmasculine children (3-9 years old) and adolescents (10-17 years old) enrolled in integrated health care systems in California and Georgia. Ten male and 10 female referent cisgender enrollees were matched to each TGNC individual on year of birth, race and/or ethnicity, study site, and membership year of the index date (first evidence of gender nonconforming status)...
April 16, 2018: Pediatrics
https://www.readbyqxmd.com/read/29660028/reoperation-for-medulloblastoma-prior-to-adjuvant-therapy
#11
Prayash Patel, David Wallace, Frederick A Boop, Brandy Vaughn, Giles W Robinson, Amar Gajjar, Paul Klimo
BACKGROUND: Surgery remains an integral part of the treatment of medulloblastoma. We present our experience with repeat surgery for this tumor before initiation of adjuvant therapy. OBJECTIVE: To report what was found intraoperatively and where at time of second-look surgery and detail any postoperative events or readmissions within 90 days of surgery. METHODS: Two separate institutional databases were queried to identify patients who underwent repeat resection of suspected residual medulloblastoma from January 2003 to January 2017...
April 11, 2018: Neurosurgery
https://www.readbyqxmd.com/read/29658383/comparison-of-the-cost-effectiveness-of-biologic-drugs-used-for-moderate-to-severe-psoriasis-treatment-in-the-united-states
#12
Jashin J Wu, Steven R Feldman, Shipra Rastogi, Brandy Menges, Melissa Lingohr-Smith, Jay Lin
PURPOSE: To compare the cost-effectiveness of the newly approved biologic drug, brodalumab, with other commonly used biologics for the treatment of moderate-to-severe psoriasis in the U.S. METHODS: An economic model was constructed in Excel to compare average costs to achieve Psoriasis Area and Severity Index (PASI) 75, 90, and 100 among moderate-to-severe psoriasis patients treated with biologics. Total annual costs to health plans associated with treatment with 5 different biologics were estimated and cost-effectiveness compared using the estimated average cost per PASI 75, PASI 90, and PASI 100...
April 16, 2018: Journal of Dermatological Treatment
https://www.readbyqxmd.com/read/29655954/corrigendum-to-a-systematic-review-of-clozapine-induced-myocarditis-int-j-cardiol-259-2018-122-129
#13
Brandi L Bellissima, Malcolm D Tingle, Aleksandar Cicović, Mohammed Alawami, Christopher Kenedi
No abstract text is available yet for this article.
April 11, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29649031/low-level-of-vegetative-state-after-traumatic-brain-injury-in-a-swiss-academic-hospital
#14
Federica Stretti, Stephanie Klinzing, Ulrike Ehlers, Peter Steiger, Reto Schuepbach, Tanja Krones, Giovanna Brandi
BACKGROUND: No standards exist regarding decision making for comatose patients, especially concerning life-saving treatments. The aim of this retrospective, single-center study was to analyze outcomes and the decision-making process at the end of life (EOL) in patients with traumatic brain injury (TBI) in a Swiss academic tertiary care hospital. METHODS: Consecutive admissions to the surgical intensive care unit (ICU) with stays of at least 48 hours between January 1, 2012 and June 30, 2015 in patients with moderate to severe TBI and with fatality within 6 months after trauma were included...
April 11, 2018: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/29643198/development-of-a-real-time-rt-pcr-assay-for-the-global-differentiation-of-yellow-fever-virus-vaccine-adverse-events-from-natural-infections
#15
Holly R Hughes, Brandy J Russell, Eric C Mossel, John Kayiwa, Julius Lutwama, Amy J Lambert
Yellow fever (YF) is a reemerging public health threat with frequent outbreaks prompting large vaccination campaigns in endemic regions of Africa and South America. Specific detection of vaccine-related adverse events is resource-intensive, time-consuming and difficult to achieve during an outbreak. To address this, we have developed a highly transferable, rapid yellow fever virus (YFV) vaccine-specific real-time RT-PCR assay that distinguishes vaccine from wild-type lineages. The assay utilizes a specific hydrolysis probe that includes locked nucleic acids to enhance specific discrimination of the YFV 17D vaccine strain genome...
April 11, 2018: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/29642719/impact-of-pharmacist-physician-collaboration-on-osteoporosis-treatment-rates
#16
Brandi L Bowers, Amy M Drew, Christian Verry
BACKGROUND: The vast majority of women at high risk for osteoporotic fractures are not treated, despite known significant clinical and economic consequences of this prevalent condition. To date, this is the first study of this size and duration to examine the role of pharmacists in management of osteoporosis in a family medicine clinic. OBJECTIVE: To compare the initiation or continuation of prescription antifracture therapy in high-risk patients with collaborative pharmacist-physician to physician-only management; secondarily, to evaluate recommendation rates for antifracture therapy and calcium and vitamin D...
April 1, 2018: Annals of Pharmacotherapy
https://www.readbyqxmd.com/read/29621799/curriculum-based-language-assessment-with-culturally-and-linguistically-diverse-students-in-the-context-of-mathematics
#17
Brandi L Newkirk-Turner, Valerie E Johnson
Purpose: The purpose of this tutorial is to discuss the use of curriculum-based language assessment (CBLA) with students who are English language learners and students who speak nonmainstream varieties of English, such as African American English. Method: The article begins with a discussion of the discourse of mathematics and the role of the speech-language pathologist (SLP), followed by a review of studies that includes those that examined the performance of English language learner and nonmainstream dialect-speaking students on word-based math items...
April 5, 2018: Language, Speech, and Hearing Services in Schools
https://www.readbyqxmd.com/read/29619540/understanding-osteoporotic-pain-and-its-pharmacological-treatment
#18
REVIEW
R Vellucci, R Terenzi, J A Kanis, H G Kress, R D Mediati, J-Y Reginster, R Rizzoli, M L Brandi
Osteoporosis, a disorder that affects millions of people worldwide, is characterized by decreased bone mass and microstructural alterations giving rise to an increased risk of fractures. Osteoporotic fractures can cause acute and chronic pain that mainly affects elderly patients with multiple comorbidities and commonly on different drug regimens. The aim of this paper is to summarize the pathogenesis and systemic treatment of osteoporotic pain. This narrative review summarizes the main pathogenetic aspects of osteoporotic pain and the cornerstones of its treatment...
April 4, 2018: Osteoporosis International
https://www.readbyqxmd.com/read/29618071/image-guidance-for-ventricular-shunt-surgery-an-analysis-of-ventricular-size-and-proximal-revision-rates
#19
Nickalus R Khan, Michael DeCuypere, Brandy N Vaughn, Paul Klimo
BACKGROUND: Image guidance is a promising technology that could lead to lower rates of premature shunt failure by decreasing the rate of inaccurate proximal catheter placement. OBJECTIVE: To perform a detailed radiographic analysis of ventricular size using 3 well-described methods and compare proximal revision rates. METHODS: Our shunt surgery research database was queried to identify procedures (new placement or revision) where frameless stereotactic electromagnetic neuronavigation was used (January 2010-June 2016)...
April 3, 2018: Neurosurgery
https://www.readbyqxmd.com/read/29616419/clinical-presentation-and-management-of-patients-with-primary-hyperparathyroidism-in-italy
#20
F Saponaro, F Cetani, A Repaci, U Pagotto, C Cipriani, J Pepe, S Minisola, C Cipri, F Vescini, A Scillitani, A Salcuni, S Palmieri, C Eller-Vainicher, I Chiodini, B Madeo, E Kara, E Castellano, G Borretta, L Gianotti, F Romanelli, V Camozzi, A Faggiano, S Corbetta, L Cianferotti, M L Brandi, M L De Feo, A Palermo, G Vezzoli, F Maino, M Scalese, C Marcocci
PURPOSE: Evaluation of the phenotype of primary hyperparathyroidism (PHPT), adherence to International Guidelines for parathyroidectomy (PTx), and rate of surgical cure. METHOD: From January 2014-January 2016, we performed a prospective, multicenter study in patients with newly diagnosed PHPT. Biochemical and instrumental data were collected at baseline and during 1-year follow-up. RESULTS: Over the first year we enrolled 604 patients (age 61 ± 14 years), mostly women (83%), referred for further evaluation and treatment advice...
April 3, 2018: Journal of Endocrinological Investigation
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