keyword
MENU ▼
Read by QxMD icon Read
search

MCM

keyword
https://www.readbyqxmd.com/read/28530570/enhanced-antimicrobial-activity-of-essential-oil-components-immobilized-on-silica-particles
#1
María Ruiz-Rico, Édgar Pérez-Esteve, Andrea Bernardos, Félix Sancenón, Ramón Martínez-Máñez, María D Marcos, José M Barat
The antimicrobial activity of essential oils components (EOCs) is well-known. However, their high volatility and powerful aroma limit their application in the formulation of a wide range of food products. In this context, the antimicrobial activity of carvacrol, eugenol, thymol and vanillin grafted onto the surface of three silica supports with different morphologies, textural properties and chemical reactivities (fumed silica, amorphous silica and MCM-41) was evaluated herein. Materials characterization revealed a good immobilization yield and all the devices showed a micro-scale particle size...
October 15, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28525881/preparation-of-mesoporous-cs-pom-mof-199-mcm-41-under-two-different-synthetic-methods-for-a-highly-oxidesulfurization-of-dibenzothiophene
#2
Si-Wen Li, Jia-Rong Li, Qi-Ping Jin, Zhi Yang, Rong-Lan Zhang, Rui-Min Gao, Jian-She Zhao
Two different synthetic methods, the direct method and the substitution method, were used to synthesize the Cs-POM@MOF-199@MCM-41 (Cs-PMM), in which the modified heteropolyacid with cesium salt has been encapsulated into the pores with the mixture of MOF and MCM-41. The structural properties of the as-prepared catalysts were characterized using various analytical techniques: powder X-ray diffraction, FT-IR, SEM, TEM, XPS and BET, confirming that the Cs-POM active species retained its Keggin structure after immobilization...
April 15, 2017: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/28525331/an-immunohistochemical-analysis-of-lymphocytic-infiltrations-in-canine-skin-cancers
#3
J A Madej, J P Madej, S Dzimira, M Nowak
Lymphocytic infiltrations located in the extracellular matrix often accompany canine skin cancer. They can be characterised as an inflammatory infiltration and/or a second tumour - lymphoma. The aim of this study was an immunohistochemical analysis of a lymphocytic infiltration which accompanies spontaneous skin cancer. Twenty basal cell carcinoma, 20 non-keratinizing squamous cell carcinoma, 20 keratinizing squamous cell carcinoma and 8 sebaceous gland carcinoma samples which were accompanied by a lymphocytic infiltration and/or secondary lymphatic follicles were verified histopathologically...
March 28, 2017: Polish Journal of Veterinary Sciences
https://www.readbyqxmd.com/read/28524659/synthesis-molecular-docking-molecular-dynamics-studies-and-biological-evaluation-of-4h-chromone-1-2-3-4-tetrahydropyrimidine-5-carboxylate-derivatives-as-potential-anti-leukemic-agents
#4
Zahra Dolatkhah, Shahrzad Javanshir, Ahmad Shahir Sadr, Jaber Hosseini, Soroush Sardari
A series of 4H-chromone-1,2,3,4-tetrahydropyrimidine-5-carboxylates derivatives were synthesized via a three component one-pot condensation of chromone-3-carbaldehyde, alkyl acetoacetate, and urea or thiourea, using MCM-41-SO3H as efficient nanocatalysts and evaluated for their anticancer activity using a combined in silico docking and molecular dynamics protocol to estimate the binding affinity of the title compounds with the Bcr-Abl oncogene. Two programs, AutoDock 4 and AutoDock Vina software were applied to dock the target protein with synthesized compounds and ATP...
May 19, 2017: Journal of Chemical Information and Modeling
https://www.readbyqxmd.com/read/28521161/visible-light-photo-fenton-oxidation-of-phenol-with-rgo-%C3%AE-feooh-supported-on-al-doped-mesoporous-silica-mcm-41-at-neutral-ph-performance-and-optimization-of-the-catalyst
#5
Ying Wang, Mingxing Liang, Jiasheng Fang, Jun Fu, Xiaochun Chen
In this study, α-FeOOH on reduced graphene oxide (rGO-α-FeOOH) supported on an Al-doped MCM-41 catalyst (RFAM) was optimized for the visible-light photo-Fenton oxidation of phenol at neutral pH. The stability of the catalysts, effect of bubbling aeration, and degradation intermediates were investigated. Results indicated that RFAM with a large Brunauer-Emmett-Teller (BET) area and mesoporous structure displayed excellent catalytic activity for the visible-light-driven (VLD) photo-Fenton process. Phenol degradation was well described by a pseudo-first-order reaction kinetics model...
May 7, 2017: Chemosphere
https://www.readbyqxmd.com/read/28518076/facile-preparation-of-ultrafine-aluminum-hydroxide-particles-with-or-without-mesoporous-mcm-41-in-ambient-environments
#6
Viktor Dubovoy, Ravi Subramanyam, Michael Stranick, Laurence Du-Thumm, Long Pan
An aqueous suspension of nanogibbsite was synthesized via the titration of aluminum aqua acid [Al(H2O)6](3+) with L-arginine to pH 4.6. Since the hydrolysis of aqueous aluminum salts is known to produce a wide array of products with a wide range of size distributions, a variety of state-of-the-art instruments (i.e., (27)Al/(1)H NMR, FTIR, ICP-OES, TEM-EDX, XPS, XRD, and BET) were used to characterize the synthesis products and identification of byproducts. The product, which was comprised of nanoparticles (10-30 nm), was isolated using gel permeation chromatography (GPC) column technique...
May 11, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28516862/non-essential-mcm-related-proteins-mediate-a-response-to-dna-damage-in-the-archaeon-methanococcus-maripaludis
#7
Alison D Walters, James P J Chong
The single minichromosome maintenance (MCM) protein found in most archaea has been widely studied as a simplified model for the MCM complex that forms the catalytic core of the eukaryotic replicative helicase. Organisms of the order Methanococcales are unusual in possessing multiple MCM homologues. The Methanococcus maripaludis S2 genome encodes four MCM homologues, McmA-McmD. DNA helicase assays reveal that the unwinding activity of the three MCM-like proteins is highly variable despite sequence similarities and suggests additional motifs that influence MCM function are yet to be identified...
May 18, 2017: Microbiology
https://www.readbyqxmd.com/read/28512278/use-of-collagen-matrix-for-augmentation-of-the-peri-implant-soft-tissue-at-the-time-of-immediate-implant-placement
#8
Gregor-Georg Zafiropoulos, Gordon John
AIM: The aim of this study was to determine the treatment outcome of the use of a porcine monolayer collagen matrix (mCM) to augment peri-implant soft tissue in conjunction with immediate implant placement as an alternative to patient's own connective tissue. MATERIALS AND METHODS: A total of 27 implants were placed immediately in 27 patients (14 males and 13 females, with a mean age of 52.2 years) with simultaneous augmentation of the soft tissue by the use of a mCM...
May 1, 2017: Journal of Contemporary Dental Practice
https://www.readbyqxmd.com/read/28507434/enhanced-oral-bioavailability-of-valsartan-using-a-polymer-based-supersaturable-self-microemulsifying-drug-delivery-system
#9
Dong Woo Yeom, Bo Ram Chae, Ho Yong Son, Jin Han Kim, Jun Soo Chae, Seh Hyon Song, Dongho Oh, Young Wook Choi
A novel, supersaturable self-microemulsifying drug delivery system (S-SMEDDS) was successfully formulated to enhance the dissolution and oral absorption of valsartan (VST), a poorly water-soluble drug, while reducing the total quantity for administration. Poloxamer 407 is a selectable, supersaturating agent for VST-containing SMEDDS composed of 10% Capmul(®) MCM, 45% Tween(®) 20, and 45% Transcutol(®) P. The amounts of SMEDDS and Poloxamer 407 were chosen as formulation variables for a 3-level factorial design...
2017: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/28498654/template-mediated-ni-ii-dispersion-in-mesoporous-sio2-for-preparation-of-highly-dispersed-ni-catalysts-influence-of-template-type
#10
Xin Ning, Yiyuan Lu, Heyun Fu, Haiqin Wan, Zhaoyi Xu, Shourong Zheng
Supported Ni catalysts on three mesoporous SiO2 supports (e.g. SBA-15, MCM-41 and HMS) were prepared by a solid state reaction between Ni(NO3)2 and organic template occluded mesoporous SiO2. For comparison, supported Ni catalysts on mesoporous SiO2 prepared by the conventional impregnation method were also included. The catalysts were characterized by scanning electron microscope, X-ray diffraction, UV-Vis diffuse reflectance spectroscopy, N2 adsorption, X-ray photoelectron spectroscopy, H2 temperature-programmed reduction, transmission electron microscopy, and transmission electron microscopy-energy dispersive X-ray...
May 12, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28497125/mapping-ubiquitination-sites-of-s-cerevisiae-mcm10
#11
Tianji Zhang, Brandy L Fultz, Sapna Das-Bradoo, Anja-Katrin Bielinsky
Minichromosome maintenance protein (Mcm) 10 is a part of the eukaryotic replication machinery and highly conserved throughout evolution. As a multivalent DNA scaffold, Mcm10 coordinates the action of proteins that are indispensable for lagging strand synthesis, such as the replication clamp, proliferating cell nuclear antigen (PCNA). The binding between Mcm10 and PCNA serves an essential function during DNA elongation and is mediated by the ubiquitination of Mcm10. Here we map lysine 372 as the primary attachment site for ubiquitin on S...
December 2016: Biochemistry and Biophysics Reports
https://www.readbyqxmd.com/read/28494590/linking-silica-support-morphology-to-the-dynamics-of-aminopolymers-in-composites
#12
Jan-Michael Y Carrillo, Matthew E Potter, Miles A Sakwa-Novak, Simon H Pang, Christopher W Jones, Bobby G Sumpter
A combined computational and experimental approach is used to elucidate the effect of silica support morphology on polymer dynamics and CO2 adsorption capacities in aminopolymer/silica composites. Simulations are based on coarse-grained molecular dynamics simulations of aminopolymer composites where a branched aminopolymer, representing poly(ethylenimine) (PEI), is impregnated into different silica mesoporous supports. The morphology of the mesoporous supports varies from hexagonally packed cylindrical pores representing SBA-15, double gyroids representing KIT-6 and MCM-48, and cagelike structures representing SBA-16...
May 23, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/28483032/advances-in-diagnosis-and-management-of-mitochondrial-cardiomyopathy
#13
Ruiqi Zhuge, Rong Zhou, Xinhai Ni
Mitochondrial cardiomyopathy (MCM) is a series of myocardial conditions characterized by abnormal heart-muscle structure,function,or both,secondary to genetic defects involving the mitochondrial respiratory chain,in the absence of concomitant coronary artery disease,hypertension,valvular disease,or congenital heart disease. MCM patients typically have hypertrophic or dilated cardiomyopathy. Arrhythmias and left ventricular myocardial noncompaction are less common,and heart failure may occur as the first symptom in some patients...
April 20, 2017: Zhongguo Yi Xue Ke Xue Yuan Xue Bao. Acta Academiae Medicinae Sinicae
https://www.readbyqxmd.com/read/28481876/oncogenic-activity-of-amplified-miniature-chromosome-maintenance-8-in-human-malignancies
#14
D-M He, B-G Ren, S Liu, L-Z Tan, K Cieply, G Tseng, Y P Yu, J-H Luo
Miniature chromosome maintenance (MCM) proteins play critical roles in DNA replication licensing, initiation and elongation. MCM8, one of the MCM proteins playing a critical role in DNA repairing and recombination, was found to have overexpression and increased DNA copy number in a variety of human malignancies. The gain of MCM8 is associated with aggressive clinical features of several human cancers. Increased expression of MCM8 in prostate cancer is associated with cancer recurrence. Forced expression of MCM8 in RWPE1 cells, the immortalized but non-transformed prostate epithelial cell line, exhibited fast cell growth and transformation, while knock down of MCM8 in PC3, DU145 and LNCaP cells induced cell growth arrest, and decreased tumour volumes and mortality of severe combined immunodeficiency mice xenografted with PC3 and DU145 cells...
May 8, 2017: Oncogene
https://www.readbyqxmd.com/read/28476962/polyethylenimine-modified-curcumin-loaded-mesoporus-silica-nanoparticle-mcm-41-induces-cell-death-in-mcf-7-cell-line
#15
Lakshminarasimhan Harini, Bose Karthikeyan, Sweta Srivastava, Srinag Bangalore Suresh, Cecil Ross, Georgepeter Gnanakumar, Srinivasan Rajagopal, Krishnan Sundar, Thandavarayan Kathiresan
Breast cancer accounts for the first highest mortality rate in India and second in world. Though current treatment strategies are effectively killing cancer cells, they also end in causing severe side effects and drug resistance. Curcumin is a nutraceutical with multipotent activity but its insolubility in water limits its therapeutic potential as an anti-cancer drug. The hydrophilicity of curcumin could be increased by nanoformulation or changing its functional groups. In this study, curcumin is loaded on mesoporous silica nanoparticle and its anti-cancer activity is elucidated with MCF-7 cell death...
February 2017: IET Nanobiotechnology
https://www.readbyqxmd.com/read/28476157/microglia-amplify-inflammatory-activation-of-astrocytes-in-manganese-neurotoxicity
#16
Kelly S Kirkley, Katriana A Popichak, Maryam F Afzali, Marie E Legare, Ronald B Tjalkens
BACKGROUND: As the primary immune response cell in the central nervous system, microglia constantly monitor the microenvironment and respond rapidly to stress, infection, and injury, making them important modulators of neuroinflammatory responses. In diseases such as Parkinson's disease, Alzheimer's disease, multiple sclerosis, and human immunodeficiency virus-induced dementia, activation of microglia precedes astrogliosis and overt neuronal loss. Although microgliosis is implicated in manganese (Mn) neurotoxicity, the role of microglia and glial crosstalk in Mn-induced neurodegeneration is poorly understood...
May 5, 2017: Journal of Neuroinflammation
https://www.readbyqxmd.com/read/28476080/investigating-the-heavy-metal-adsorption-of-mesoporous-silica-materials-prepared-by-microwave-synthesis
#17
Wenjie Zhu, Jingxuan Wang, Di Wu, Xitong Li, Yongming Luo, Caiyun Han, Wenhui Ma, Sufang He
Mesoporous silica materials (MSMs) of the MCM-41 type were rapidly synthesized by microwave heating using silica fume as silica source and evaluated as adsorbents for the removal of Cu(2+), Pb(2+), and Cd(2+) from aqueous solutions. The effects of microwave heating times on the pore structure of the resulting MSMs were investigated as well as the effects of different acids which were employed to adjust the solution pH during the synthesis. The obtained MCM-41 samples were characterized by nitrogen adsorption-desorption analyses, X-ray powder diffraction, and transmission electron microscopy...
December 2017: Nanoscale Research Letters
https://www.readbyqxmd.com/read/28465488/rack1-promotes-lung-cancer-cell-growth-via-an-mcm7-rack1-akt-signaling-complex
#18
Liangru Fei, Yinan Ma, Meiyu Zhang, Xiaofang Liu, Yuan Luo, Congcong Wang, Haiyan Zhang, Wenzhu Zhang, Yuchen Han
MCM7, a member of the miniature chromosome maintenance (MCM) protein family, is crucial for the initiation of DNA replication and proliferation in eukaryotic cells. In this report, we demonstrate that RACK1 regulates cell growth and cell cycle progression in human non-small-cell lung cancer by mediating MCM7 phosphorylation through an MCM7/RACK1/Akt signaling complex. RACK1 functions as a central scaffold that brings Akt into physical proximity with MCM7. Overexpression of RACK1 increases interactions between Akt and MCM7 and promotes Akt-dependent MCM7 phosphorylation, which in turn increases MCM7 binding to chromatin and MCM complex formation...
April 15, 2017: Oncotarget
https://www.readbyqxmd.com/read/28459842/phosphorylated-stat5-directly-facilitates-parvovirus-b19-dna-replication-in-human-erythroid-progenitors-through-interaction-with-the-mcm-complex
#19
Safder S Ganaie, Wei Zou, Peng Xu, Xuefeng Deng, Steve Kleiboeker, Jianming Qiu
Productive infection of human parvovirus B19 (B19V) exhibits high tropism for burst forming unit erythroid (BFU-E) and colony forming unit erythroid (CFU-E) progenitor cells in human bone marrow and fetal liver. This exclusive restriction of the virus replication to human erythroid progenitor cells is partly due to the intracellular factors that are essential for viral DNA replication, including erythropoietin signaling. Efficient B19V replication also requires hypoxic conditions, which upregulate the signal transducer and activator of transcription 5 (STAT5) pathway, and phosphorylated STAT5 is essential for virus replication...
May 2017: PLoS Pathogens
https://www.readbyqxmd.com/read/28459566/a-heterogeneous-gold-i-catalyzed-2-2-1-annulation-of-terminal-alkynes-nitriles-and-oxygen-atoms-leading-to-2-5-disubstituted-oxazoles
#20
Weisen Yang, Rongli Zhang, Feiyan Yi, Mingzhong Cai
The first heterogeneous gold(I)-catalyzed [2 + 2 + 1] annulation of terminal alkynes, nitriles, and oxygen atoms has been achieved by using an MCM-41-immobilized phosphine-gold(I) complex as catalyst and 8-methylquinoline N-oxide as oxidant under mild conditions, yielding a variety of 2,5-disubstituted oxazoles in good to excellent yields with broad substrate scope. The new heterogeneous gold(I) catalyst can easily be recovered by simple filtration of the reaction solution and recycled for at least eight times without significant loss of activity...
May 1, 2017: Journal of Organic Chemistry
keyword
keyword
36218
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"