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https://www.readbyqxmd.com/read/28806620/a-novel-intestinal-rotation-method-for-digestive-reconstruction-after-combined-pancreaticoduodenectomy-and-extended-right-hemicolectomy-a-case-report-and-surgical-technique
#1
Kosei Takagi, Takahito Yagi, Yuzo Umeda, Ryuichi Yoshida, Daisuke Nobuoka, Takashi Kuise, Kenjiro Kumano, Takeshi Kojima, Takuro Fushimi, Toshiyoshi Fujiwara
INTRODUCTION: Pancreaticoduodenectomy (PD) combined with extended right hemicolectomy (RH) is a challenging procedure for locally advanced malignancies. However, information concerning the reconstruction method of the digestive system is limited. Here, we present a case and surgical technique of a novel intestinal rotation method for digestive reconstruction after PD combined with RH. PRESENTATION OF CASE: A 62-year-old man with locally advanced pancreatic cancer received conversion surgery combined with PD and RH after preoperative chemotherapy...
August 8, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28806516/scalable-and-facile-preparation-of-highly-stretchable-electrospun-pedot-pss-pu-fibrous-nonwovens-towards-wearable-conductive-textile-applications
#2
Yichun Ding, Wenhui Xu, Wenyu Wang, Hao Fong, Zhengtao Zhu
Flexible and stretchable conductive textiles are highly desired for potential applications in wearable electronics. This study demonstrates a scalable and facile preparation of all-organic nonwoven that is mechanically stretchable and electrically conductive. Polyurethane (PU) fibrous nonwoven is prepared via the electrospinning technique; in the following step, the electrospun PU nonwoven is dip-coated with the conducting polymer poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate) (PEDOT:PSS). This simple method enables convenient preparation of PEDOT:PSS@PU nonwovens with initial sheet resistance in the range of 35~240 Ω/ sq (i...
August 14, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28805370/chirality-transfer-from-chiral-monoamines-to-an-m-phthalic-diamide-linked-zinc-bisporphyrinate-with-a-benzylamide-substituent
#3
Qingyun Hu, Congcong Zhuo, Yong Wang, Chuanjiang Hu, Jianping Lang
An m-phthalic diamide-linked bisporphyrin with a benzylamide substituent has been designed and synthesized. It has two types of carbonyl groups. In the solution of this zinc bisporphyrinate, these carbonyl groups are involved in the formation of two different Zn-O coordination interactions: one is formed between neighboring zinc bisporphyrinates; another is formed within zinc bisporphyrinate. The chirality sensing abilities of this zinc porphyrinate to a number of chiral monoamines have been examined. When zinc bisporphyrinate was mixed with a series of chiral monoamines, the signs of the circular dichroism spectra for the chiral monoamines of the same handedness with an aryl group as the substituent are just opposite to those with an alkyl group as the substituent...
August 14, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/28805224/molecular-dynamics-based-strength-estimates-of-beta-solenoid-proteins
#4
Amanda Parker, Krishnakumar Ravikumar, Daniel Cox
The use of beta solenoid proteins as functionalizable, nanoscale, self-assembling molecular building blocks may have many applications, including templating the growth of wires or higher-dimensional structures. By understanding their mechanical strengths, we can efficiently design the proteins for specific functions. We present a study of the mechanical properties of seven beta solenoid proteins using GROMACS molecular dynamics software to produce force/torque-displacement data, implement umbrella sampling of bending/twisting trajectories, produce Potentials of Mean Force (PMFs), extract effective spring constants, and calculate rigidities for two bending and two twisting directions for each protein...
August 14, 2017: Soft Matter
https://www.readbyqxmd.com/read/28800324/fluid-in-the-tissue-channels-of-vascular-adventitia-investigated-by-afm-and-tem
#5
Xinxiao Han, Hongyi Li, Wenda Hua, Luru Dai, Zhuo Ao, Fulong Liao, Dong Han
BACKGROUND: Tissue channels as a part of microcirculation system have been proposed over three decade, playing an important role in fluid transportation as reported. Adventitia of inferior vena cava (IVC) is a typical hierarchical porous media with abundant tissue channels. Its fluid transportation behaviors attract massive research interest. However, the mechanism of the driving force and microstructure was lack of deep research. OBJECTIVE: This study was to investigate the microstructural basis of fluid transportation within inferior vena cava (IVC)...
August 11, 2017: Clinical Hemorheology and Microcirculation
https://www.readbyqxmd.com/read/28795731/twisting-induces-ferromagnetism-in-homometallic-clusters
#6
Ghenadie Novitchi, Sergi Vela, Guillaume Pilet, Cyrille Train, Vincent Robert
A helical chiral cluster bridging two sets of Cu2 units is reported. The two double-stranded ligands induce a distorted tetrahedral environment for one of the two copper(ii) ions whereas the second one remains in a standard octahedral environment. Magnetic measurements and wavefunction calculations demonstrate that the copper(ii) centres are ferromagnetically coupled (J = 7.7 cm(-1)). This ligand-driven ferromagnetic interaction thus appears as a proof-of-concept of an innovative strategy towards high-spin clusters...
August 10, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/28794228/long-axis-twisting-during-locomotion-of-elongate-fishes
#7
Cassandra M Donatelli, A P Summers, E D Tytell
Fish live in a complex world and must actively adapt their swimming behavior to a range of environments. Most studies of swimming kinematics focus on two-dimensional properties related to the bending wave that passes from head to tail. However, fish also twist their bodies in 3D around their longitudinal axis as the bending wave passes down the body. We measured and characterized this movement, which we call 'wobble', in six species of elongate fishes (Anoplarchus insignis, Xiphister mucosus, Lumpenus sagitta, Pholis laeta, Apodichthys flavidus, and Ronquilus jordani) from three different habitats (intertidal, nearshore, and subtidal) using custom video analysis software...
August 9, 2017: Journal of Experimental Biology
https://www.readbyqxmd.com/read/28793797/the-many-faces-of-long-noncoding-rnas-in-cancer
#8
Xue Wu, Oana Tudoran, George Calin, Mircea Ivan
SIGNIFICANCE: The emerging connections between an increasing number of long noncoding RNAs (lncRNAs) and oncogenic hallmarks provide a new twist to tumor complexity. Recent Advances: In the present review, we highlight specific lncRNAs that have been studied in relationship to tumorigenesis, either as participants to the neoplastic process or as markers of pathway activity or drug response. These transcripts are typically deregulated by oncogenic or tumor-suppressing signals, or respond to microenvironmental conditions such as hypoxia...
August 10, 2017: Antioxidants & Redox Signaling
https://www.readbyqxmd.com/read/28793343/a-new-approach-for-the-pre-clinical-optimization-of-a-spatial-configuration-of-bifurcated-endovascular-prosthesis-placed-in-abdominal-aortic-aneurysms
#9
Andrzej Polanczyk, Aleksandra Piechota-Polanczyk, Ludomir Stefańczyk
Complexity of the spatial configuration of an aortic implant with bifurcation in the distal part is related to changes in blood hemodynamic in the area of bifurcation which may disturb blood flow and lead to thrombus formation. This study was designed to characterize parameters which define spatial configuration of an aortic implant for which the risk of thrombus formation is the smallest. We used AngioCT data from 74 patients, aged 55 ±10 years, after endovascular procedure to prepare 3D geometries of stent-grafts...
2017: PloS One
https://www.readbyqxmd.com/read/28793213/critical-influence-of-cosolutes-and-surfaces-on-the-assembly-of-serpin-derived-amyloid-fibrils
#10
Michael W Risør, Dennis W Juhl, Morten Bjerring, Joachim Mathiesen, Jan J Enghild, Niels C Nielsen, Daniel E Otzen
Many proteins and peptides self-associate into highly ordered and structurally similar amyloid cross-β aggregates. This fibrillation is critically dependent on properties of the protein and the surrounding environment that alter kinetic and thermodynamic equilibria. Here, we report on dominating surface and solution effects on the fibrillogenic behavior and amyloid assembly of the C-36 peptide, a circulating bioactive peptide from the α1-antitrypsin serine protease inhibitor. C-36 converts from an unstructured peptide to mature amyloid twisted-ribbon fibrils over a few hours when incubated on polystyrene plates under physiological conditions through a pathway dominated by surface-enhanced nucleation...
August 8, 2017: Biophysical Journal
https://www.readbyqxmd.com/read/28792893/large-stroke-high-fidelity-pzn-pt-single-crystal-stake-actuator
#11
Yu Huang, Yue Xue Xia, Dian Hua Lin, Kui Yao, Leong Chew Lim
A new piezoelectric actuator design, called "Stake" actuator, is proposed and demonstrated in this work. As an example, the stake actuator is made of four d32-mode PZN-5.5%PT single crystals, each of 25mmL × 8mmW × 0.4mmT in dimensions, bonded with the aid of polycarbonate (PC) edge guide-cum-stiffeners into a square-pipe configuration for improved bending and twisting strengths and capped with top and bottom pedestals made of 1.5 mm thick anodized aluminium. The resultant stake actuator measured 9 mm × 9 mm × 28 mm...
August 3, 2017: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
https://www.readbyqxmd.com/read/28792036/probing-the-interplay-between-geometric-and-electronic-structure-in-a-two-dimensional-k-tcnq-charge-transfer-network
#12
P J Blowey, L A Rochford, D A Duncan, D A Warr, T-L Lee, D P Woodruff, G Costantini
Scanning tunnelling microscopy (STM), low energy electron diffraction (LEED), ultraviolet and soft X-ray photoelectron spectroscopy (UPS and SXPS) have been used to characterise the formation of a coadsorption phase of TCNQ and K on Ag(111), while the normal incident X-ray standing waves (NIXSW) technique has been used to obtain quantitative structural information. STM and LEED show that an ordered incommensurate phase is formed in which the K atoms are surrounded by four TCNQ molecules in a 'windmill' motif, characteristic of other metal/TCNQ phases, in which the nominal TCNQ : K stoichiometry is 1 : 1...
August 9, 2017: Faraday Discussions
https://www.readbyqxmd.com/read/28791647/analysis-of-epithelial-mesenchymal-transition-induced-by-overexpression-of-twist
#13
Jing-Wen Bai, Yong-Qu Zhang, Yao-Chen Li, Guo-Jun Zhang
Breast cancer, the most common malignancy among women worldwide, is a heterogeneous disease, and it therefore has remarkably different biological characteristics and clinical behavior. Breast cancer has been divided into several different molecular subtypes based on the status of estrogen receptor (ER), progesterone receptor (PR), human epidermal growth factor 2 (HER2, also named as ErbB2) status. Her2 is a member of EGFR family of transmembrane tyrosine kinase-type receptors, and is involved in the activation of its downstream signaling cascades, which could promote cell proliferation, metastasis, and angiogenesis in tumors...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28791480/a-more-realistic-disc-herniation-model-incorporating-compression-flexion-and-facet-constrained-shear-a-mechanical-and-microstructural-analysis-part-ii-high-rate-or-surprise-loading
#14
Zhi Shan, Kelly R Wade, Meredith L Schollum, Peter A Robertson, Ashvin Thambyah, Neil D Broom
PURPOSE: Part I of this study explored mechanisms of disc failure in a complex posture incorporating physiological amounts of flexion and shear at a loading rate considerably lower than likely to occur in a typical in vivo manual handling situation. Given the strain-rate-dependent mechanical properties of the heavily hydrated disc, loading rate will likely influence the mechanisms of disc failure. Part II investigates the mechanisms of failure in healthy discs subjected to surprise-rate compression while held in the same complex posture...
August 8, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28791412/benzo-a-pyrene-enhances-the-emt-associated-migration-of-lung-adenocarcinoma-a549-cells-by-upregulating-twist1
#15
Xi Chen, Hongbing Peng, Jian Xiao, Anqi Guan, Bin Xie, Bixiu He, Qiong Chen
Benzo(a)pyrene (BaP), an important toxic component of cigarette smoke, can cause lung cancer and lead to the progression of lung cancer. In the present study, we investigated the effect of BaP on the migration of lung adenocarcinoma A549 cells. BaP (1 µM) promoted the migration of A549 cells in a time-dependent manner and upregulated the expression of the Twist family BHLH transcription factor 1 (Twist1). BaP also induced upregulation of the mesenchymal markers N-cadherin and vimentin and downregulation of the epithelial marker E-cadherin...
August 3, 2017: Oncology Reports
https://www.readbyqxmd.com/read/28790318/evolution-of-the-electronic-band-structure-of-twisted-bilayer-graphene-upon-doping
#16
Shengqiang Huang, Matthew Yankowitz, Kanokporn Chattrakun, Arvinder Sandhu, Brian J LeRoy
The electronic band structure of twisted bilayer graphene develops van Hove singularities whose energy depends on the twist angle between the two layers. Using Raman spectroscopy, we monitor the evolution of the electronic band structure upon doping using the G peak area which is enhanced when the laser photon energy is resonant with the energy separation of the van Hove singularities. Upon charge doping, the Raman G peak area initially increases for twist angles larger than a critical angle and decreases for smaller angles...
August 8, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28790029/twisted-intra-abdominal-cyst-in-a-neonate-a-surprise-revelation
#17
Ferzine Mohamed, Ramesh Babu Telugu, Immanuel Sampath Karl
We, herein, present a male neonate with an antenatally detected intra-abdominal cyst who presented at 18 days of life at which time, the ultrasound revealed a 5×4 cm cyst. Since he was asymptomatic, we planned to repeat the ultrasound a month later and operate if the cyst showed no regression. However, a week later, he presented with an acute abdomen, irritable cry and a repeat ultrasound showing a larger (8×6 cm) cystic mass with debris within. He was taken up for an emergency laparotomy. Intraoperatively, the cyst was found arising from the left lateral abdominal wall free from all structures with a twisted pedicle...
August 8, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28789939/bioremediation-3-0-engineering-pollutant-removing-bacteria-in-the-times-of-systemic-biology
#18
REVIEW
Pavel Dvořák, Pablo I Nikel, Jiří Damborský, Víctor de Lorenzo
Elimination or mitigation of the toxic effects of chemical waste released to the environment by industrial and urban activities relies largely on the catalytic activities of microorganisms-specifically bacteria. Given their capacity to evolve rapidly, they have the biochemical power to tackle a large number of molecules mobilized from their geological repositories through human action (e.g., hydrocarbons, heavy metals) or generated through chemical synthesis (e.g., xenobiotic compounds). Whereas naturally occurring microbes already have considerable ability to remove many environmental pollutants with no external intervention, the onset of genetic engineering in the 1980s allowed the possibility of rational design of bacteria to catabolize specific compounds, which could eventually be released into the environment as bioremediation agents...
August 5, 2017: Biotechnology Advances
https://www.readbyqxmd.com/read/28783083/fluorescent-polystyrene-films-for-the-detection-of-volatile-organic-compounds-using-the-twisted-intramolecular-charge-transfer-mechanism
#19
Mirko Borelli, Giuseppe Iasilli, Pierpaolo Minei, Andrea Pucci
Thin films of styrene copolymers containing fluorescent molecular rotors were demonstrated to be strongly sensitive to volatile organic compounds (VOCs). Styrene copolymers of 2-[4-vinyl(1,1'-biphenyl)-4'-yl]-cyanovinyljulolidine (JCBF) were prepared with different P(STY-co-JCBF)(m) compositions (m% = 0.10-1.00) and molecular weights of about 12,000 g/mol. Methanol solutions of JCBF were not emissive due to the formation of the typical twisted intramolecular charge transfer (TICT) state at low viscosity regime, which formation was effectively hampered by adding progressive amounts of glycerol...
August 6, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28782959/line-tension-of-twist-free-carbon-nanotube-lyotropic-liquid-crystal-microdroplets-on-solid-surfaces
#20
Vida Jamali, Evan Gregory Biggers, Paul van der Schoot, Matteo Pasquali
Line tension, i.e., the force on a three-phase contact line, has been a subject of extensive research due to its impact on technological applications including nanolithography and nanofluidics. However, there is no consensus on the sign and magnitude of the line tension, mainly because it only affects the shape of small droplets, below the length scale dictated by the ratio of line tension to surface tension σ/τ. This ratio is related to the size of constitutive molecules in the system, which translates to a nanometer for conventional fluids...
August 7, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
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