keyword
MENU ▼
Read by QxMD icon Read
search

Slow wave sleep

keyword
https://www.readbyqxmd.com/read/28735929/electrophysiological-and-microstructural-features-of-sleep-in%C3%A2-children%C3%A2-at-high-risk-for-depression-a-preliminary-study
#1
Gianluca Sesso, Flora Bat-Pitault, Aurore Guyon, Sabine Plancoulaine, Tommaso Banfi, Giulia Milioli, Liborio Parrino, Ugo Faraguna, Patricia Franco
OBJECTIVE: This preliminary study investigated electrophysiological and microstructural features of sleep in children and adolescents 4-18 years of age who were born to depressed mothers. METHODS: A total of 31 healthy subjects (15 male and 16 female) participated in the study. In this sample, 20 children born to mothers diagnosed with Major Depressive Disorder (MDD) were designated as "high-risk"; 11 children born to mothers without a personal history of depression were designated as "low-risk...
August 2017: Sleep Medicine
https://www.readbyqxmd.com/read/28735928/efficacy-and-safety-of-almorexant-in-adult-chronic-insomnia-a-randomized-placebo-controlled-trial-with-an-active-reference
#2
Jed Black, Giora Pillar, Jan Hedner, Olli Polo, Ouali Berkani, Sara Mangialaio, Abdel Hmissi, Gary Zammit, Goran Hajak
BACKGROUND AND OBJECTIVES: The orally active dual OX1R and OX2R antagonist, almorexant, targets the orexin system for the treatment of primary insomnia. This clinical trial assessed the effect of almorexant on sleep maintenance and other sleep endpoints, and its safety and tolerability in adults. PATIENTS AND METHODS: Prospective, randomized, double-blind, placebo-controlled, active referenced trial in male and female adults aged 18-64 years with chronic, primary insomnia...
August 2017: Sleep Medicine
https://www.readbyqxmd.com/read/28734769/influence-of-epileptic-activity-during-sleep-on-cognitive-performance-in-benign-childhood-epilepsy-with-centrotemporal-spikes
#3
Andreea Nissenkorn, Adi Pappo, Yael Feldmann, Gali Heimer, Omer Bar-Yosef, Michal Tzadok, Orli Polack, Ayelet Bord, Miriam Levav, Bruria Ben-Zeev
BACKGROUND: Benign childhood epilepsy with centrotemporal spikes is benign childhood epilepsy, presenting between 4 and 10 years of age, characterized by typical clinical and EEG findings. Despite excellent prognosis, there are reports of mild cognitive, language, fine motor and behavioral difficulties. In its atypical form - electrical status epilepticus during slow wave sleep, continuous epileptiform activity during sleep lead to severe neurocognitive deterioration. Our objective was to investigate the influence of abundant sleep epileptiform activity, not fulfilling the criteria for electrical status epilepticus during Slow Wave Sleep, discovered randomly in children without overt intellectual impairment...
July 11, 2017: European Journal of Paediatric Neurology: EJPN
https://www.readbyqxmd.com/read/28729692/extensive-astrocyte-synchronization-advances-neuronal-coupling-in-slow-wave-activity-in-vivo
#4
Zsolt Szabó, László Héja, Gergely Szalay, Orsolya Kékesi, András Füredi, Kornélia Szebényi, Árpád Dobolyi, Tamás I Orbán, Orsolya Kolacsek, Tamás Tompa, Zsombor Miskolczy, László Biczók, Balázs Rózsa, Balázs Sarkadi, Julianna Kardos
Slow wave activity (SWA) is a characteristic brain oscillation in sleep and quiet wakefulness. Although the cell types contributing to SWA genesis are not yet identified, the principal role of neurons in the emergence of this essential cognitive mechanism has not been questioned. To address the possibility of astrocytic involvement in SWA, we used a transgenic rat line expressing a calcium sensitive fluorescent protein in both astrocytes and interneurons and simultaneously imaged astrocytic and neuronal activity in vivo...
July 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28729438/electrophysiological-evidence-that-the-retrosplenial-cortex-displays-a-strong-and-specific-activation-phased-with-hippocampal-theta-during-paradoxical-rem-sleep
#5
Koike Bruna Del Vechio, Farias Kelly Soares, Billwiller Francesca, Almeida-Filho Daniel, Libourel Paul-Antoine, Tiran-Cappello Alix, Parmentier Régis, Blanco Wilfredo, Ribeiro Sidarta, Luppi Pierre-Herve, Queiroz Claudio Marcos
It is widely accepted that cortical neurons are similarly more activated during waking and paradoxical sleep (PS, aka REM) than during slow wave sleep (SWS). However, we recently reported using Fos labeling that only a few limbic cortical structures including the retrosplenial (RSC) and anterior cingulate (ACA) cortices contain a large number of neurons activated during PS hypersomnia. Our aim in the present study was to record local field potentials (LFPs) and unit activity from these two structures across all vigilance states in freely moving male rats to determine whether the RSC and the ACA are electrophysiologically specifically active during basal PS episodes...
July 20, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28729115/arousal-and-drug-abuse
#6
REVIEW
Francisco J Urbano, Verónica Bisagno, Edgar Garcia-Rill
The reticular activating system (RAS) is not an amorphous region but distinct nuclei with specific membrane properties that dictate their firing during waking and sleep. The locus coeruleus and raphe nucleus fire during waking and slow wave sleep, with the pedunculopontine nucleus (PPN) firing during both waking and REM sleep, the states manifesting arousal-related EEG activity. Two important discoveries in the PPN in the last 10 years are, 1) that some PPN cells are electrically coupled, and 2) every PPN cell manifests high threshold calcium channels that allow them to oscillate at beta/gamma band frequencies...
July 17, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/28722021/activation-of-the-gabaergic-parafacial-zone-maintains-sleep-and-counteracts-the-wake-promoting-action-of-the-psychostimulants-armodafinil-and-caffeine
#7
C Anaclet, K Griffith, P M Fuller
We previously reported that acute and selective activation of GABA-releasing parafacial zone (PZ(Vgat)) neurons in behaving mice produces slow-wave-sleep (SWS), even in the absence of sleep deficit, suggesting that these neurons may represent, at least in part, a key cellular substrate underlying sleep drive. It remains however to be determined if PZ(Vgat) neurons actively maintain, as oppose to simply gate, SWS. To begin to experimentally address this knowledge gap, we asked whether activation of PZ(Vgat) neurons could attenuate or block the wake-promoting effects of two widely used wake-promoting psychostimulants, armodafinil or caffeine...
July 19, 2017: Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28712436/association-of-symptoms-of-insomnia-and-sleep-parameters-among-kidney-transplant-recipients
#8
Katalin Z Ronai, Andras Szentkiralyi, Alpar S Lazar, Zsolt I Lazar, Istvan Papp, Ferenc Gombos, Rezso Zoller, Maria E Czira, Anett V Lindner, Istvan Mucsi, Robert Bodizs, Miklos Z Molnar, Marta Novak
OBJECTIVE: Insomnia complaints are frequent among kidney transplant (kTx) recipients and are associated with fatigue, depression, lower quality of life and increased morbidity. However, it is not known if subjective insomnia symptoms are associated with objective parameters of sleep architecture. Thus, we analyze the association between sleep macrostructure and EEG activity versus insomnia symptoms among kTx recipients. METHODS: Participants (n1=100) were selected from prevalent adult transplant recipients (n0=1214) followed at a single institution...
August 2017: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/28702729/improvement-of-the-night-sleep-quality-by-electrocutaneous-subthreshold-stimulation-synchronized-with-the-slow-wave-sleep
#9
Yu V Gulyaev, A S Bugaev, P A Indursky, V M Shakhnarovich, V V Dementienko
Changes in sleep characteristics were studied under the non-wake-up stimulation with current pulses of less than 1 μA on average, applied to the palmar surface skin receptors during Δ-sleep. A significant increase in duration of the first and second cycles of deep sleep has been found, as well as a shorter latent period before the Δ-sleep onset and a longer time of the rapid sleep (REM phase). The sleep structure improvement was accompanied by the reduced reactive anxiety and depression and an increase in subjective physical efficiency...
May 2017: Doklady Biological Sciences: Proceedings of the Academy of Sciences of the USSR, Biological Sciences Sections
https://www.readbyqxmd.com/read/28697944/vocabulary-learning-benefits-from-rem-after-slow-wave-sleep
#10
Laura J Batterink, Carmen E Westerberg, Ken A Paller
Memory reactivation during slow-wave sleep (SWS) influences the consolidation of recently acquired knowledge. This reactivation occurs spontaneously during sleep but can also be triggered by presenting learning-related cues, a technique known as targeted memory reactivation (TMR). Here we examined whether TMR can improve vocabulary learning. Participants learned the meanings of 60 novel words. Auditory cues for half the words were subsequently presented during SWS in an afternoon nap. Memory performance for cued versus uncued words did not differ at the group level but was systematically influenced by REM sleep duration...
July 8, 2017: Neurobiology of Learning and Memory
https://www.readbyqxmd.com/read/28691719/narcolepsy-type-1-and-hypersomnia-associated-with-a-psychiatric-disorder-show-different-slow-wave-activity-dynamics
#11
Ewa Walacik-Ufnal, Anna Justyna Piotrowska, Dorota Wołyńczyk-Gmaj, Piotr Januszko, Bartłomiej Gmaj, Marcin Ufnal, Marek Kabat, Marcin Wojnar
The aim of the study was to compare electrophysiological parameters of night sleep in narcolepsy type 1 and hypersomnia associated with a psychiatric disorder. Fortyfour patients: 15 with narcolepsy type 1, 14 with hypersomnia associated with a psychiatric disorder and 15 age- and sex-matched controls participated in the study. The study subjects filled in the Athens Insomnia Scale (AIS) and the Beck Depression Inventory (BDI). The severity of daytime sleepiness was quantified subjectively using the Epworth Sleepiness Scale (ESS) and the Stanford Sleepiness Scale (SSS), and objectively using the Multiple Sleep Latency Test (MSLT)...
2017: Acta Neurobiologiae Experimentalis
https://www.readbyqxmd.com/read/28690583/correlating-interictal-spikes-with-sigma-and-delta-dynamics-during-non-rapid-eye-movement-sleep
#12
Frédéric Zubler, Annalisa Rubino, Giorgio Lo Russo, Kaspar Schindler, Lino Nobili
Interictal spikes (IS) are one of the major hallmarks of epilepsy. Understanding the factors promoting or suppressing IS would increase our comprehension of epilepsy and possibly open new avenues for therapy. Sleep strongly influences epileptic activity, and the modulatory effects of the different sleep stages on IS have been studied for decades. However, several aspects are still disputed, in particular the role of sleep spindles and slow waves in the activation of IS during Non-REM sleep. Here, we correlate the rate of IS with quantitative measures derived from stereo-EEG during one Non-REM cycle in 10 patients suffering from drug-resistant epilepsy due to type 2 focal cortical dysplasia...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28683451/sleep-related-electrophysiology-and-behavior-of-tinamous-eudromia-elegans-tinamous-do-not-sleep-like-ostriches
#13
Ryan K Tisdale, Alexei L Vyssotski, John A Lesku, Niels C Rattenborg
The functions of slow wave sleep (SWS) and rapid eye movement (REM) sleep, distinct sleep substates present in both mammals and birds, remain unresolved. One approach to gaining insight into their function is to trace the evolution of these states through examining sleep in as many taxonomic groups as possible. The mammalian and avian clades are each composed of two extant groups, i.e., the monotremes (echidna and platypus) and therian (marsupial and eutherian [or placental]) mammals, and Palaeognaths (cassowaries, emus, kiwi, ostriches, rheas, and tinamous) and Neognaths (all other birds) among birds...
July 7, 2017: Brain, Behavior and Evolution
https://www.readbyqxmd.com/read/28680119/increased-stability-and-breakdown-of-brain-effective-connectivity-during-slow-wave-sleep-mechanistic-insights-from-whole-brain-computational-modelling
#14
Beatrice M Jobst, Rikkert Hindriks, Helmut Laufs, Enzo Tagliazucchi, Gerald Hahn, Adrián Ponce-Alvarez, Angus B A Stevner, Morten L Kringelbach, Gustavo Deco
Recent research has found that the human sleep cycle is characterised by changes in spatiotemporal patterns of brain activity. Yet, we are still missing a mechanistic explanation of the local neuronal dynamics underlying these changes. We used whole-brain computational modelling to study the differences in global brain functional connectivity and synchrony of fMRI activity in healthy humans during wakefulness and slow-wave sleep. We applied a whole-brain model based on the normal form of a supercritical Hopf bifurcation and studied the dynamical changes when adapting the bifurcation parameter for all brain nodes to best match wakefulness and slow-wave sleep...
July 5, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28679286/local-differences-in-computational-sleep-depth-parameters-in-healthy-school-aged-children
#15
Sari-Leena Himanen, Eero Huupponen, Marjukka Jussila, Anna-Maria Lapinlampi, Outi Saarenpää-Heikkilä
OBJECTIVE: Slow wave sleep in children reflects several processes, such as sleep pressure, synaptic density, and cortical maturation. Deep sleep in children is abundant and our aim was to discover whether examining electroencephalography (EEG) mean frequency would help separate these processes. METHODS: Sleep EEG of 28 generally healthy 7- to 11-year-old children (14 first graders, 14 third graders, 14 girls, 14 boys) was analyzed. Median non-rapid eye movement (NREM) sleep EEG frequency (median sleep depth, in Hz) and the amount of computational deep sleep using the thresholds of 2 Hz and 4 Hz (DS2% and DS4%, respectively) were calculated from the frontopolar, central, and occipital EEG derivations...
July 1, 2017: Clinical EEG and Neuroscience: Official Journal of the EEG and Clinical Neuroscience Society (ENCS)
https://www.readbyqxmd.com/read/28676764/bed-rest-and-hypoxic-exposure-affect-sleep-architecture-and-breathing-stability
#16
Shawnda A Morrison, Dani Mirnik, Spela Korsic, Ola Eiken, Igor B Mekjavic, Leja Dolenc-Groselj
Objective: Despite over 50 years of research on the physiological effects of sustained bed rest, data characterizing its effects on sleep macrostructure and breathing stability in humans are scarce. This study was conducted to determine the effects of continuous exposure to hypoxia and sustained best rest, both individually and combined, on nocturnal sleep and breathing stability. Methods: Eleven participants completed three randomized, counter-balanced, 21-days trials of: (1) normoxic bed rest (NBR, PIO2 = 133...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28674176/effects-of-chronic-social-defeat-stress-on-sleep-and-circadian-rhythms-are-mitigated-by-kappa-opioid-receptor-antagonism
#17
Audrey M Wells, Elysia Ridener, Clinton A Bourbonais, Woori Kim, Harry Pantazopoulos, F Ivy Carroll, Kwang-Soo Kim, Bruce M Cohen, William A Carlezon
Stress plays a critical role in the neurobiology of mood and anxiety disorders. Sleep and circadian rhythms are affected in many of these conditions. Here we examined the effects of chronic social defeat stress (CSDS), an ethological form of stress, on sleep and circadian rhythms. We exposed male mice implanted with wireless telemetry transmitters to a 10-day CSDS regimen known to produce anhedonia (a depressive-like effect) and social avoidance (an anxiety-like effect). Electroencephalography (EEG), electromyography (EMG), body temperature, and locomotor activity data were collected continuously during the CSDS regimen and a 5-day recovery period...
July 3, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28673592/bottom-up-gamma-and-stages-of-waking
#18
E Garcia-Rill
Gamma activity has been proposed to promote the feed forward or "bottom-up" flow of information from lower to higher regions of the brain during perception. The pedunculopontine nucleus (PPN) modulates waking and REM sleep, and is part of the reticular activating system (RAS). The properties of PPN cells are unique in that all PPN neurons fire maximally at gamma band frequency regardless of electrophysiological or transmitter type, thus proposed as one origin of "bottom-up" gamma. This property is based on the presence of intrinsic membrane oscillations subserved by high threshold, voltage-dependent calcium channels...
July 2017: Medical Hypotheses
https://www.readbyqxmd.com/read/28667703/hippocampal-gamma-slow-oscillation-coupling-in-macaques-during-sedation-and-sleep
#19
Andrew G Richardson, Xilin Liu, Pauline K Weigand, Eric D Hudgins, Joel M Stein, Sandhitsu R Das, Alexander Proekt, Max B Kelz, Milin Zhang, Jan Van der Spiegel, Timothy H Lucas
Behavioral and neurophysiological evidence suggests that the slow (≤ 1 Hz) oscillation (SO) during sleep plays a role in consolidating hippocampal (HIPP)-dependent memories. The effects of the SO on HIPP activity have been studied in rodents and cats both during natural sleep and during anesthetic administration titrated to mimic sleep-like slow rhythms. In this study, we sought to document these effects in primates. First, HIPP field potentials were recorded during ketamine-dexmedetomidine sedation and during natural sleep in three rhesus macaques...
July 1, 2017: Hippocampus
https://www.readbyqxmd.com/read/28658343/overweight-in-youth-and-sleep-quality-is-there-a-link
#20
Susana Rebelo Pacheco, Ana Margalha Miranda, Raquel Coelho, Ana Cristina Monteiro, Graciete Bragança, Helena Cristina Loureiro
Objective: Overweight seems to be related to a higher prevalence of sleep disturbances. Decreased sleep duration and altered sleep quality are risk factors for obesity. Our aim was to compare the sleep pattern of overweight children with that of a matched control group and assess the relationship between sleep quality and obesity. Materials and methods: Retrospective cohort study comparing 41 overweight children with a normal-weight control group, both submitted to polysomnography...
June 26, 2017: Archives of Endocrinology and Metabolism
keyword
keyword
36211
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"