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the pseudotumor cerebri syndrome

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https://www.readbyqxmd.com/read/27903844/therapeutic-approaches-to-pediatric-pseudotumor-cerebri-new-insights-from-literature-data
#1
Giovanna Vitaliti, Piero Pavone, Nassim Matin, Omidreza Tabatabaie, Salvatore Cocuzza, Michele Vecchio, Luigi Maiolino, Paola Di Mauro, Angelo Conti, Riccardo Lubrano, Agostino Serra, Raffaele Falsaperla
The pseudotumor cerebri syndrome (PTCS), also known as idiopathic intracranial hypertension (IIH), is characterized by signs and symptoms of increased intracranial pressure such as headache and cranial nerve palsies, in the absence of any space-occupying mass. This condition commonly affects overweight women of childbearing age, even if it is also frequent in men and children. Children with PTCS may present with atypical signs and symptoms, with a different prognosis compared to adults. However, the treatment is the same for both children and adults, even if there are no strict treatment guidelines in regards...
November 30, 2016: International Journal of Immunopathology and Pharmacology
https://www.readbyqxmd.com/read/27825557/probable-pseudotumor-cerebri-complex-in-25-children-further-support-of-a-concept
#2
Daniel Tibussek, Felix Distelmaier, Michael Karenfort, Stefani Harmsen, Dirk Klee, Ertan Mayatepek
BACKGROUND: Cerebrospinal fluid (CSF) opening pressure (OP) of ≥28 cm H2O is now considered a diagnostic criterion for Pseudotumor cerebri syndrome (PTCS) in children. However, it has been proposed that a diagnosis of "probable" PTCS can be made with an OP < 28 cm H2O if other diagnostic criteria are met. We report a group of children with probable PTCS. METHODS: Retrospective analysis of 25 children diagnosed with PTCS but with a CSF OP below 28 cm H2O...
October 27, 2016: European Journal of Paediatric Neurology: EJPN
https://www.readbyqxmd.com/read/27786584/medication-related-pseudotumor-cerebri-syndrome
#3
Olga R Thon, John W Gittinger
Pseudotumor cerebri syndrome refers to elevated intracranial pressure associated with papilledema without an identified etiology for intracranial hypertension. Over the past few decades, several medications have been described to be associated with this syndrome. We searched the literature for those case reports and series and evaluated the evidence for the association of such medications with pseudotumor cerebri syndrome.
October 27, 2016: Seminars in Ophthalmology
https://www.readbyqxmd.com/read/27743925/subarachnoid-hemorrhage-following-angioplasty-and-stenting-in-a-patient-with-primitive-drainage-pattern-of-the-basal-vein-of-rosenthal
#4
Rustum Karanjia, Alfredo A Sadun, Angelos A Konstas
Severe visual loss may occur in patients with pseudotumor cerebri (PTC), also known as idiopathic intracranial hypertension. Transverse sinus stenosis is 1 cause of PTC syndrome. Although the role of transverse sinus stenosis in the pathogenesis of the disease remains controversial, recent case series of transverse sinus stenting have reported very high rates of symptom response and resolution of papilledema with improvement or at least stabilization of the visual fields and visual acuity (Ahmed et al., 2011)...
October 12, 2016: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/27681952/surgical-treatment-of-pseudotumor-cerebri
#5
Hamza Karabag, Mehtap Kocaturk, Kadri Burak Ethemoglu, Ozlem Ethemoglu, Ahmet Celal Iplikcioglu
AIM: To share our experience with idiopathic intracranial hypertension. MATERIAL AND METHODS: All patients believed to have pseudotumor cerebri underwent a fundus oculi examination to confirm the existence of papillary stasis and lumbar puncture (LP) to measure cerebrospinal fluid (CSF) pressure. Patients who did not respond to medical treatment underwent fundus oculi examinations at 3-week intervals. Patients with CFS pressures exceeding 240 mm H2O underwent at least three LPs at 3-day intervals...
2016: Annali Italiani di Chirurgia
https://www.readbyqxmd.com/read/27430448/visual-impairment
#6
Carl Ellenberger
This chapter can guide the use of imaging in the evaluation of common visual syndromes: transient visual disturbance, including migraine and amaurosis fugax; acute optic neuropathy complicating multiple sclerosis, neuromyelitis optica spectrum disorder, Leber hereditary optic neuropathy, and Susac syndrome; papilledema and pseudotumor cerebri syndrome; cerebral disturbances of vision, including posterior cerebral arterial occlusion, posterior reversible encephalopathy, hemianopia after anterior temporal lobe resection, posterior cortical atrophy, and conversion blindness...
2016: Handbook of Clinical Neurology
https://www.readbyqxmd.com/read/27409508/pediatric-optical-coherence-tomography-in-clinical-practice-recent-progress
#7
Helena Lee, Frank A Proudlock, Irene Gottlob
PURPOSE: Optical coherence tomography (OCT) has revolutionized the diagnosis and management of adult retinal and optic nerve disease. Children were deprived of this technology until the recent development of handheld spectral-domain OCT (HH-SDOCT). In this article, we review the applications of OCT imaging in pediatric ophthalmology. METHODS: This study was a review of the literature. RESULTS: The acquisition and interpretation of pediatric tomograms differ significantly from those for adults, with adjustments needed to account for the shorter axial lengths, higher refractive errors, and ongoing retinal and optic nerve development in the pediatric eye...
July 1, 2016: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/27244842/presumed-pseudotumor-cerebri-syndrome-after-withdrawal-of-inhaled-glucocorticoids
#8
Young Joon Kwon, Julian L Allen, Grant T Liu, Shana E McCormack
Pseudotumor cerebri syndrome (PTCS) is characterized by increased intracranial pressure with normal brain parenchyma and cerebrospinal fluid constituents. PTCS after withdrawal of systemic corticosteroids also has been described in children. In contrast, to our knowledge, PTCS after withdrawal of inhaled glucocorticoids has not previously been described. Here we report the case of an 8-year and 6-month-old girl who developed signs and symptoms consistent with PTCS after withdrawal of inhaled glucocorticoids...
June 2016: Pediatrics
https://www.readbyqxmd.com/read/27079408/-pseudotumor-cerebri-secondary-to-consumption-of-minocycline-in-a-pediatric-patient
#9
Lucas O González Gili, Ignacio R Buffone, Laura E Carrara, María B Coto, Eliana A Fortunatti, Mabel Dejtera, María F García Elliot, Alejandra Giacone, Anabella C Luncio, Sebastián D Masnicoff, María B Oviedo Crosta, Marianela Parroua, Mariana Romano
Pseudotumor cerebri is a syndrome characterized by an elevated intracranial pressure greater than 20 cmH2O with ventricles and cerebrospinal fluid of normal characteristics. Consumption of minocycline have been described among the causes associated with this syndrome. We present a 13-year old female patient with a history of acne treated with minocycline who began with severe headache, diplopia and blurred vision. The diagnosis of pseudotumor cerebri was made, indicating the immediate antibiotic suspension and the beginning of the treatment with acetazolamide...
April 2016: Archivos Argentinos de Pediatría
https://www.readbyqxmd.com/read/26709738/farris-tang-retractor-in-optic-nerve-sheath-decompression-surgery
#10
Jennifer A Spiegel, Jason A Sokol, Thomas J Whittaker, Benjamin Bernard, Bradley K Farris
PURPOSE: Our purpose is to introduce the use of the Farris-Tang retractor in optic nerve sheath decompression surgery. METHODS: The procedure of optic nerve sheath fenestration was reviewed at our tertiary care teaching hospital, including the use of the Farris-Tang retractor. RESULTS: Pseudotumor cerebri is a syndrome of increased intracranial pressure without a clear cause. Surgical treatment can be effective in cases in which medical therapy has failed and disc swelling with visual field loss progresses...
2016: Orbit
https://www.readbyqxmd.com/read/26411233/a-case-of-idiopathic-intracranial-hypertension-associated-with-pcos
#11
Y J Lee, J E Jeong, J K Joo, K S Lee
Idiopathic intracranial hypertension (IIH) is a rare neurologic disorder. It is also known as pseudotumor cerebri. The incidence of IIH is one to two per 100,000 population annually. The higher incidence is in obese women from 15 to 44 years. The main symptoms are headache and visual loss. It mostly affects women of childbearing age who are overweight or obese. There are many theories of pathogenesis of IIH, but precise pathogenesis is unknown. One of the causes of IIH is intracranial venous sinus thrombosis...
2015: Clinical and Experimental Obstetrics & Gynecology
https://www.readbyqxmd.com/read/26222108/factors-affecting-visual-loss-and-visual-recovery-in-patients-with-pseudotumor-cerebri-syndrome
#12
Clara L Afonso, Aley Talans, Mário Luiz Ribeiro Monteiro
PURPOSE: To investigate the frequency of visual loss (VL), possible predictive factors of VL, and improvement in patients with pseudotumor cerebri (PTC) syndrome. METHODS: We reviewed 50 PTC patients (43 females, seven males) who underwent neuro-ophthalmic examination at the time of diagnosis and after treatment. Demographic data, body mass index (BMI), time from symptom onset to diagnosis (TD), maximum intracranial pressure (MIP), occurrence of cerebral venous thrombosis (CVT), and treatment modalities were reviewed...
May 2015: Arquivos Brasileiros de Oftalmologia
https://www.readbyqxmd.com/read/26122540/neuro-ophthalmology-and-neuro-otology-update
#13
REVIEW
Daniel R Gold, David S Zee
This review summarizes topical papers from the fields of neuro-ophthalmology and neuro-otology published from August 2013 to February 2015. The main findings are: (1) diagnostic criteria for pseudotumor cerebri have been updated, and the Idiopathic Intracranial Hypertension Treatment Trial evaluated the efficacy of acetazolamide in patients with mild vision loss, (2) categorization of vestibular disorders through history and ocular motor examination is particularly important in the acute vestibular syndrome, where timely distinction between a central or peripheral localization is essential, (3) the newly described "sagging eye syndrome" provides a mechanical explanation for an isolated esodeviation that increases at distance in the aging population and (4) eye movement recordings better define how cerebellar dysfunction and/or sixth nerve palsy may play a role in other patients with esodeviations that increase at distance...
December 2015: Journal of Neurology
https://www.readbyqxmd.com/read/26079334/papilledema-and-vision-loss-caused-by-jugular-paragangliomas
#14
Paweena Lertakyamanee, Ashok Srinivasan, Lindsey B De Lott, Jonathan D Trobe
Paragangliomas that arise from the jugular bulb are known to present as masses in the neck or with hearing loss, pulsatile tinnitus, and lower cranial nerve palsies. Much less recognized is their tendency to cause increased intracranial pressure and papilledema by obstructing jugular venous outflow. Only 7 such cases have been reported and with minimal ophthalmic documentation. We describe 3 more cases to provide additional documentation and to emphasize that paragangliomas are a potential cause of the pseudotumor cerebri syndrome, and that papilledema may be overlooked when a jugular paraganglioma is diagnosed or after it has been treated...
December 2015: Journal of Neuro-ophthalmology: the Official Journal of the North American Neuro-Ophthalmology Society
https://www.readbyqxmd.com/read/26047166/relationship-between-pattern-electroretinogram-frequency-domain-oct-and-automated-perimetry-in-chronic-papilledema-from-pseudotumor-cerebri-syndrome
#15
COMPARATIVE STUDY
Clara L Afonso, Ali S Raza, André C Kreuz, Kenzo Hokazono, Leonardo P Cunha, Maria K Oyamada, Mário L R Monteiro
PURPOSE: We evaluated the ability of transient pattern electroretinogram (PERG) parameters to differentiate between eyes with visual field (VF) loss and resolved papilledema from pseudotumor cerebri syndrome (PTC) and controls, to compare PERG and optical coherence tomography (OCT) with regard to discrimination ability, and to assess the correlation between PERG, frequency domain OCT (FD-OCT), and VF measurements. METHODS: The VFs and full-field stimulation PERGs based on 48 and 14-min checks were obtained from patients with PTC (n = 24, 38 eyes) and controls (n = 26, 34 eyes)...
June 2015: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/26021731/lumboatrial-shunt-in-a-patient-with-crouzon-syndrome-complicated-by-pseudotumor-cerebri
#16
Eric W Sankey, Mohamed H Khattab, Benjamin D Elder, C Rory Goodwin, Harold L Rekate, Daniele Rigamonti
A 25-year-old man with Crouzon syndrome complicated by pseudotumor cerebri and multiple shunt failures presented with progressive back and neck pain, intermittent headaches, and associated vomiting secondary to shunt infection. Due to his previous history of repeated failure of both ventriculoperitoneal and lumboperitoneal (LP) shunting procedures, the decision was made to place a lumboatrial (LA) shunt via an approach through the internal jugular vein. The procedure was uncomplicated and the man's symptoms were relieved...
September 2015: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/25973659/intra-abdominal-hypertension-and-abdominal-compartment-syndrome-in-burns-obesity-pregnancy-and-general-medicine
#17
REVIEW
Manu L N G Malbrain, Bart L De Keulenaer, Jun Oda, Inneke De Laet, Jan J De Waele, Derek J Roberts, Andrew W Kirkpatrick, Edward Kimball, Rao Ivatury
Intra-abdominal hypertension (IAH) is an important contributor to early organ dysfunction in trauma and sepsis. However, relatively little is known about the impact of intra-abdominal pressure (IAP) in general internal medicine, pregnant patients, and those with obesity or burns. The aim of this paper is to review the pathophysiologic implications and treatment options for IAH in these specific situations. A MEDLINE and PubMed search was performed and the resulting body-of-evidence included in the current review on the basis of relevance and scientific merit...
2015: Anaesthesiology Intensive Therapy
https://www.readbyqxmd.com/read/25944131/an-update-on-the-pathophysiology-of-idiopathic-intracranial-hypertension-alias-pseudotumor-cerebri
#18
REVIEW
Betül Baykan, Esme Ekizoğlu, Güneş Altıokka Uzun
Idiopathic intracranial hypertension (IIH) is a syndrome characterized by increased intracranial pressure of unknown cause, leading to severe headache, papilledema and visual disturbances. Its former name, pseudotumor cerebri, has gained popularity recently. The strongest and most consistent risk factors of IIH are obesity and female gender. Infrequently, IIH may present in the absence of papilledema showing a headache profile similar to chronic daily headache with migrainous features. There have been several proposed mechanisms to explain the etiology of this disorder associated with various clinical conditions...
2015: Aǧrı: Ağrı (Algoloji) Derneği'nin Yayın Organıdır, the Journal of the Turkish Society of Algology
https://www.readbyqxmd.com/read/25806679/acute-abducens-nerve-paralysis-in-the-pediatric-emergency-department-analysis-of-14-patients
#19
Ozlem Teksam, Ayse Gultekingil Keser, Bahadir Konuskan, Goknur Haliloglu, Kader Karli Oguz, Dilek Yalnizoglu
OBJECTIVES: Sixth cranial nerve (SCN) palsy is an uncommon but important neurological problem in patients admitted to pediatric emergency department. The underlying etiology of SCN palsy has a wide range from viral infections to intracranial tumors; therefore, a careful and systematic approach is necessary while examining these patients. METHODS: Fourteen patients who presented with acute SCN paralysis to pediatric emergency department during the last 10 years were examined...
May 2016: Pediatric Emergency Care
https://www.readbyqxmd.com/read/25622879/-usefulness-of-intracranial-pressure-continuous-monitoring-in-pseudotumor-cerebri
#20
Angel Horcajadas Almansa, Nicolás Cordero Tous, Ana Román Cutillas, Enrique Saura Rojas, Ana Jorques Infante, Benjamín Iáñez Velasco, Carlos Sánchez Corral
OBJECTIVES: To analyse the usefulness of intracranial pressure (ICP) monitoring in pseudotumor cerebri (PTC). MATERIAL AND METHODS: Ten patients with suspected PTC, but having incomplete criteria for the syndrome, on whom ICP monitoring was performed. Demographic, clinical and radiological data were collected, as well as ICP monitoring data and related complications. Results were evaluated 6 months after surgery. RESULTS: In relation to demographics, all patients were young females...
July 2015: Neurocirugía
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