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https://www.readbyqxmd.com/read/28089997/the-impact-of-age-and-sex-on-in-hospital-outcomes-of-chronic-total-occlusion-percutaneous-coronary-intervention
#1
Aris Karatasakis, Rahel Iwnetu, Barbara A Danek, Dimitri Karmpaliotis, Khaldoon Alaswad, Farouc A Jaffer, Robert W Yeh, David E Kandzari, Nicholas J Lembo, Mitul Patel, Ehtisham Mahmud, William L Lombardi, R Michael Wyman, J Aaron Grantham, Anthony H Doing, Catalin Toma, James W Choi, Barry F Uretsky, Jeffrey W Moses, Ajay J Kirtane, Ziad A Ali, Manish Parikh, Judit Karacsonyi, Bavana V Rangan, Craig A Thompson, Subhash Banerjee, Emmanouil S Brilakis
OBJECTIVES: We sought to determine the effect of age and sex on procedural outcomes and efficiency of chronic total occlusion (CTO) percutaneous coronary intervention (PCI). METHODS: We examined the clinical and angiographic characteristics and outcomes of 1675 CTO-PCIs performed in 1644 patients between 2012 and 2016 at 15 United States centers. RESULTS: Mean age was 65.3 ± 10 years and 1408 (86%) were men. Overall technical and procedural success rates were 88% and 87%, respectively...
January 15, 2017: Journal of Invasive Cardiology
https://www.readbyqxmd.com/read/28060128/pulmonary-nodule-size-5-mm-still-warrants-investigation-in-patients-with-osteosarcoma-and-ewing-sarcoma
#2
Jared Kusma, Cody Young, Han Yin, Joseph R Stanek, Nicholas Yeager, Jennifer H Aldrink
BACKGROUND: Osteosarcoma (OS) and Ewing sarcoma (ES) have a high propensity to develop pulmonary metastases. Lung lesions with calcification, peripheral location, and size >5 mm are more likely to represent malignant metastases. We evaluated the incidence of malignancy in nodules 5 mm or less to potentially guide decisions between biopsy and observation. MATERIALS AND METHODS: A retrospective review of patients <25 years of age with metastatic OS and ES treated at our institution between 2001 and 2014 who had undergone pulmonary nodule biopsy was performed...
January 5, 2017: Journal of Pediatric Hematology/oncology
https://www.readbyqxmd.com/read/28053696/invasive-thymoma-with-pure-red-cell-aplasia-and-amegakaryocytic-thrombocytopenia
#3
Takuya Onuki, Yusuke Kiyoki, Sho Ueda, Masatoshi Yamaoka, Seiich Shimizu, Masaharu Inagaki
We here describe a case involving a 67-yearold female patient who was referred to our hospital due to severe anemia (hemoglobin, 5.0 g/dL), thrombocytopenia (platelet count, 0.6 × 10(4)/μL), and a mediastinal shadow with calcification noted on X-ray. On admission, an anterior mediastinal tumor was detected, and bone marrow biopsy revealed few megakaryocytes and severely reduced numbers of erythroid cells. The diagnosis was thymoma with pure red cell aplasia (PRCA) and acquired amegakaryocytic thrombocytopenia (AAMT)...
November 2, 2016: Hematology Reports
https://www.readbyqxmd.com/read/28043582/mediastinal-lymphadenopathy-in-pediatric-tuberculosis-in-computed-tomography-scan
#4
Payam Mehrain, Amin Momeni Moghaddam, Elham Tavakol, Afshin Amini, Mehrdad Moghimi, Ali Kabir, Ali Akbar Velayati
BACKGROUND/OBJECTIVES: Pediatric tuberculosis is usually a primary infection presenting mainly as mediastinal or hilar adenopathy in computed tomography (CT) scan. In this study, we study the distribution and other CT scan characteristics of mediastinal lymphadenopathy in childhood tuberculosis. METHODS: Chest CT scans of 75 cases of pediatric tuberculosis at Masih Daneshvari Hospital in Tehran, Iran, from 2009 to 2013 were studied regarding characteristics of mediastinal lymphadenopathy...
December 2016: International Journal of Mycobacteriology
https://www.readbyqxmd.com/read/28031656/a-very-unusual-cause-of-hemoptysis
#5
Pablo Loarte, Geraldo Holguín, Ronny Cohen
The use of Lucite balls or spheres played a role in the management of tuberculosis during the first decade of the 20th century. Several complications have been reported with the use of this surgical technique, but are rarely seen nowadays. The availability of effective oral regimens has forced to abandon this approach. Calcification of these spheres within the lung cavity produced a series of late complications result of the migration of these foreign bodies to adjacent structures, causing erosion of blood vessels and nerves...
December 2016: International Journal of Angiology: Official Publication of the International College of Angiology, Inc
https://www.readbyqxmd.com/read/28009603/crospovidone-and-microcrystalline-cellulose-a-novel-description-of-pharmaceutical-fillers-in-the-gastrointestinal-tract
#6
Sophia M Shaddy, Michael A Arnold, Konstantin Shilo, Wendy L Frankel, Alan E Harzman, Peter P Stanich, Aatur D Singhi, Martha M Yearsley, Christina A Arnold
Crospovidone and microcrystalline cellulose (MCC) are pharmaceutical fillers well known in the pulmonary pathology literature. Fillers are inactive substances incorporated into medications to facilitate drug delivery. By examining 545 consecutive gastrointestinal surgical specimens from 302 patients between September 11, 2015 and October 23, 2015, we identified the fillers in 29 specimens from 26 patients. The control group consisted of an equal number of consecutive site-matched specimens collected during this same time...
December 22, 2016: American Journal of Surgical Pathology
https://www.readbyqxmd.com/read/27990453/lung-nodule-malignancy-classification-using-only-radiologist-quantified-image-features-as-inputs-to-statistical-learning-algorithms-probing-the-lung-image-database-consortium-dataset-with-two-statistical-learning-methods
#7
Matthew C Hancock, Jerry F Magnan
In the assessment of nodules in CT scans of the lungs, a number of image-derived features are diagnostically relevant. Currently, many of these features are defined only qualitatively, so they are difficult to quantify from first principles. Nevertheless, these features (through their qualitative definitions and interpretations thereof) are often quantified via a variety of mathematical methods for the purpose of computer-aided diagnosis (CAD). To determine the potential usefulness of quantified diagnostic image features as inputs to a CAD system, we investigate the predictive capability of statistical learning methods for classifying nodule malignancy...
October 2016: Journal of Medical Imaging
https://www.readbyqxmd.com/read/27957519/low-dose-chest-ct-protocol-50%C3%A2-mas-as-a-routine-protocol-for-comprehensive-assessment-of-intrathoracic-abnormality
#8
Takeshi Kubo, Yoshiharu Ohno, Mizuki Nishino, Pei-Jan Lin, Shiva Gautam, Hans-Ulrich Kauczor, Hiroto Hatabu
PURPOSE: To determine the diagnostic capability of low-dose CT (50 mAs) in comparison to standard-dose CT (150 mAs). MATERIALS AND METHODS: Fifty-nine consecutive patients underwent two non-contrast chest CT scans with different current-time products (50 and 150 mAs at 120 kVp) on a 64-detector row CT scanner. Three board certified chest radiologists independently reviewed 118 series of 2 mm-thick images (2 series for each of 59 patients) in a random order...
2016: European Journal of Radiology Open
https://www.readbyqxmd.com/read/27957516/standard-dose-vs-low-dose-ct-protocols-in-the-evaluation-of-localized-lung-lesions-capability-for-lesion-characterization-ilead-study
#9
Takeshi Kubo, Yoshiharu Ohno, Daisuke Takenaka, Mizuki Nishino, Shiva Gautam, Kazuro Sugimura, Hans Ulrich Kauczor, Hiroto Hatabu
OBJECTIVE: To determine the lesion characterization capability by low dose CT for localized lung lesions in comparison with standard dose CT. SUBJECTS AND METHODS: Approval for this study was granted by our Institutional Review Board. Fifty-two consecutive patients (36 males and 16 females, median age of 71 years.) who had CT examinations for evaluation of lung lesions comprise the study population. Two chest CT scans were performed with current time product of 50 and 150 mAs at 120 kVp, with the same scan length with a 16 detector-row CT scanner...
2016: European Journal of Radiology Open
https://www.readbyqxmd.com/read/27931056/-guideline-s2k-awmf-of-the-deutsche-gesellschaft-f%C3%A3-r-pneumologie-und-beatmungsmedizin-and-the-deutsche-gesellschaft-f%C3%A3-r-arbeitsmedizin-und-umweltmedizin-diagnostics-and-expert-opinion-in-the-occupational-disease-no-4101-silicosis-including-coal-worker-s-pneumoconiosis
#10
X Baur, M Heger, R M Bohle, K G Hering, K Hofmann-Preiß, D Nowak, A Tannapfel, H Teschler, T Voshaar, T Kraus
During the last 1.5 years an update of the guideline on silicosis was made by an interdisciplinary working group. New medical and scientific knowledge and the experience in expert opinion practice were taken into account.By preparing the initial guideline in 2010 standardization of diagnostics and adaption of the "Moers convention" which was not based on medical knowledge was in the focus, whereas the current update deals with fine emendation and extension, especially of the compensation rate (adaption with the Reichenhall recommendation)...
December 2016: Pneumologie
https://www.readbyqxmd.com/read/27927880/serum-osteoprotegrin-opg-in-subclinical-atherosclerosis-in-systemic-lupus-erythematosus
#11
A N Kiani, P Aukrust, T Ueland, I Hollan, E Barr, L S Magder, M Petri
INTRODUCTION: Osteoprotegerin (OPG) is a member of the tumor necrosis factor (TNF) receptor family. It has recently been demonstrated that OPG is produced by a variety of tissues, including the cardiovascular system (heart, arteries, veins), lung, kidney, immune tissues, and bone. The OPG-RANKL signaling pathway is strongly related to vascular calcification. We determined the association of this biomarker with subclinical atherosclerosis in systemic lupus erythematous (SLE). METHODS: We measured OPG and markers of subclinical atherosclerosis (coronary artery calcium (CAC), carotid intima-media thickness (cIMT) carotid plaque) in 166 SLE patients (91% female, 64% Caucasian, 31% African American, 5% others, mean age 45 years)...
December 6, 2016: Lupus
https://www.readbyqxmd.com/read/27904539/the-effect-of-renal-transplantation-on-respiratory-muscle-strength-in-patients-with-end-stage-renal-disease
#12
Sasan Tavana, Samaneh Mirzaei
BACKGROUND: There is evidence of musculoskeletal and respiratory involvement in patients with chronic kidney disease (CKD). This is attributed to protein calorie imbalance that is caused by the disease process, and hemodialysis and is generally referred to as uremic myopathy. This results in calcification of respiratory muscles such as diaphragm and intercostal muscles. There are limited data about respiratory muscle strength in patients with CKD. We intended to evaluate the effect of kidney transplantation on respiratory muscles strength in patients with CKD...
2016: Tanaffos
https://www.readbyqxmd.com/read/27847015/determining-the-lymphadenopathy-characteristics-of-the-mediastinum-in-lung-ct-scan-of-children-with-tuberculosis
#13
Payam Mehrian, Amin Momeni Moghaddam, Elham Tavakkol, Afshin Amini, Mehrdad Moghimi, Ali Kabir, Aliakbar Velayati
OBJECTIVE/BACKGROUND: Most tuberculosis cases in children are primary infection, with difficult and imprecise diagnosis mainly based on the existence of mediastinal lymphadenopathy. Here, we investigated the characteristics of mediastinal lymphadenopathy in lung computed tomography (CT) scans of children with tuberculosis. METHODS: This cross-sectional study was performed on 75 children with tuberculosis referred to Masih Daneshvari Hospital in Tehran, Iran, from 2009 to 2013...
September 2016: International Journal of Mycobacteriology
https://www.readbyqxmd.com/read/27795800/-diffuse-and-calcified-nodular-opacities
#14
Hasna Jabri, Régis Gothard Bopaka, Nawal Lakhdar, Houda Moubachir, Wiam El Khattabi, Hicham Afif
Pulmonary adenocarcinoma is difficult to identify right away with respect to anamnestic and even to radiological data. We here report the case of a woman with dyspnea. Radiological examination showed disseminated micronodular opacity confluent in both lung fields with calcifications in certain locations. Histological examination of transbronchial biopsies allowed the diagnosis. The prognosis was poor with the death of the patient.
2016: Pan African Medical Journal
https://www.readbyqxmd.com/read/27788055/diagnosis-and-implications-of-mycobacterium-bovis-infection-in-banded-mongooses-mungos-mungo-in-the-kruger-national-park-south-africa
#15
Angela C Brüns, Manfred Tanner, Mark C Williams, Louise Botha, Amanda O'Brien, Geoffrey T Fosgate, Paul D van Helden, John Clarke, Anita L Michel
Bovine tuberculosis (bTB) was first diagnosed in the Kruger National Park (KNP) in 1990. Research has since focused on the maintenance host, the African buffalo ( Syncerus caffer ) and clinically affected lion ( Panthera leo ). However, little is known about the role of small predators in tuberculosis epidemiology. During 2011-12, we screened banded mongooses ( Mungos mungo ) in the bTB high-prevalence zone of the KNP for Mycobacterium tuberculosis complex members. Fecal swabs, tracheal swabs, and tracheal lavages of 76 banded mongooses caught in cage traps within a 2-km radius of Skukuza Rest Camp were submitted for Mycobacterium culture, isolation, and species identification...
January 2017: Journal of Wildlife Diseases
https://www.readbyqxmd.com/read/27776948/-what-place-for-the-thoracostomy-thoracmyoplasty-in-the-management-of-the-chronic-pleural-empyema
#16
M Lakranbi, S Rabiou, L Belliraj, I Issoufou, F Z Ammor, J Ghalimi, Y Ouadnouni, M Smahi
INTRODUCTION: The occurrence of empyema after pneumonectomy or in suites with chronic pleural pocket is a dreaded complication. The management is long and difficult. The authors report their experience before this complication including infection control by an emptying of the pleural pocket percutaneous drainage or thoracostomy which will be complemented by a thoracomyoplasty the aim to erase the pleural pocket. MATERIALS AND METHODS: This is a retrospective study conducted between 2009 and 2015 concerning the records of 9 patients treated for empyema or in the aftermath of a lung resection or as part of a chronic pleural pocket and calcific...
December 2016: Revue de Pneumologie Clinique
https://www.readbyqxmd.com/read/27766197/uremic-lung-the-calcified-cauliflower-sign-in-the-end-stage-renal-disease
#17
Giuseppe Dilorenzo, Michele Telegrafo, Giuseppe Marano, Michele De Ceglie, Amato Antonio Stabile Ianora, Giuseppe Angelelli, Marco Moschetta
Metastatic pulmonary calcification (MPC) is a rare pathological condition consisting of lung calcium salt deposits which commonly occurs in patients affected by chronic kidney disease probably for some abnormalities in calcium and phosphate metabolism. CT represents the technique of choice for detecting MPC findings including ground glass opacities and partially calcified nodules or consolidations. We present a case of MCP in a patient affected by hepato-renal autosomic-dominant polycystic disease; chest CT revealed extensive lobar-segmental parenchymal calcification with a peculiar cauliflower shape which we called "calcified cauliflower" sign...
2016: Respiratory Medicine Case Reports
https://www.readbyqxmd.com/read/27752018/severe-metastatic-calcifications-in-a-hemodialysis-patient
#18
Jannet Labidi, Yosra Ben Ariba, Abdelkader Ben Gabsia, Faida Ajili, Riadh Battikh, Bassem Louzir, Nadia Ben Abdelhafidh, Saleh I Othman
Tissue calcification is a common complication in patients on continuous hemodialysis (HD) for chronic renal failure; however, severe calcification is unusual. Three distinct clinical types of extraosseous calcifications are found in uremic patients: vascular calcification, periarticular (tumoral) calcification, and visceral calcification (heart, lung, and kidney). We report a case of a young chronic HD patient who presented with extensive metastatic calcifi cations both vascular, visceral specially localized in the lungs, and periarticular with progressively increasing multiple subcutaneous swellings...
September 2016: Saudi Journal of Kidney Diseases and Transplantation
https://www.readbyqxmd.com/read/27741976/coronary-artery-calcification
#19
REVIEW
Kazuhiro Osawa, Rine Nakanishi, Matthew Budoff
Coronary artery calcification (CAC) is an established marker of subclinical atherosclerosis and an independent predictor of future coronary heart disease in the asymptomatic primary prevention population, particularly in the intermediate risk cohort. CAC also helps in reclassifying those patients and their risk of cardiovascular events into higher or lower risk categories. MESA (Multi-Ethnic Study of Atherosclerosis) is a National Heart, Lung, and Blood Institute-sponsored population-based medical research study involving 6,814 men and women from 6 U...
September 2016: Global Heart
https://www.readbyqxmd.com/read/27708233/advanced-lung-adenocarcinomas-with-ros1-rearrangement-frequently-show-hepatoid-cell
#20
Jing Zhao, Jing Zheng, Mei Kong, Jianya Zhou, Wei Ding, Jianying Zhou
Defining distinctive histologic characteristics of ROS1-rearranged non-small-cell lung carcinomas (NSCLCs) may help identify cases that merit molecular testing. However, the majority of previous reports have focused on surgical specimens but only limited studies assessed histomorphology of advanced NSCLCs. In order to identify the clinical and histological characteristics of ROS1-rearranged advanced NSCLCs, we examined five hundred sixteen Chinese patients with advanced NSCLCs using ROS1 fluorescence in situ hybridization and real-time polymerase chain reaction and then analyzed for clinical and pathological features...
September 30, 2016: Oncotarget
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