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Skin epidemiology

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https://www.readbyqxmd.com/read/28926874/-multicenter-epidemiological-investigation-of-hospitalized-elderly-young-and-middle-aged-patients-with-severe-burn
#1
Y Tang, L X Wang, W G Xie, Z A Shen, G H Guo, J J Chen, C M Han, L C Ren, Z G Chu, M F Yin, Y Wang, D X Zhang, Y S Huang, J P Zhang
Objective: To compare and analyze the epidemiological characteristics of hospitalized elderly, young and middle-aged patients with severe burn in recent years, so as to provide reference for the prevention and treatment of elderly patients with severe burn. Methods: Relying on the entry system of epidemiological case data and biological sample of severe burn from multicenter in clinic, medical records of patients with severe burn, aged above 18, hospitalized in 8 burn wards from January 2012 to December 2015 were collected...
September 20, 2017: Zhonghua Shao Shang za Zhi, Zhonghua Shaoshang Zazhi, Chinese Journal of Burns
https://www.readbyqxmd.com/read/28925912/epidemiologic-features-of-invasive-group-a-streptococcus-infection-in-a-rural-hospital-6-year-retrospective-report-and-literature-review
#2
Kassandra Loewen, Natalie Bocking, Cai-Lei Matsumoto, Mike Kirlew, Len Kelly
INTRODUCTION: High rates of invasive group A Streptococcus disease were suspected by clinicians in northwestern Ontario. Patients with sepsis were being encountered with bacteremia positive for group A Streptococcus. This study was designed to assess the incidence of invasive group A Streptococcus infection in the region and provide best-practice treatment information. METHODS: We performed a retrospective chart review at the Sioux Lookout Meno Ya Win Health Centre (SLMHC) from 2009 to 2014 to examine rates of infection due to invasive group A Streptococcus and outcomes...
2017: Canadian Journal of Rural Medicine
https://www.readbyqxmd.com/read/28925870/pollution-and-sun-exposure-a-deleterious-synergy-mechanisms-and-opportunities-for-skin-protection
#3
Laurent Marrot
Pollutants are highly diverse chemical entities, including gases such as ozone or nitrogen and sulphur oxides and particulate matter of different sizes and with different chemical constituents. PM2.5 is composed of particles that are sometimes about ten nanometres or so in size (ultrafine particles) which can be deposited in lung alveoli, translocated into capillaries and then distributed to all organs through blood circulation. PM2.5 is often associated with toxic chemicals such as heavy metals or polycyclic aromatic hydrocarbons (PAHs) and some photo-reactive PAHs can induce strong oxidative stress under UVA exposure...
September 18, 2017: Current Medicinal Chemistry
https://www.readbyqxmd.com/read/28925103/autoimmune-diseases-involving-skin-and-intestinal-mucosa-are-more-frequent-in-adolescents-and-young-adults-suffering-from-atopic-dermatitis
#4
REVIEW
Francesca Cipriani, Alice Marzatico, Giampaolo Ricci
Evidence has emerged about the relationship between atopic dermatitis (AD) and autoimmune diseases, but the underlying mechanism of this association is complex and still unclear. Recent epidemiological data from the published work suggest a positive correlation. The aim of this review is to analyze the frequency of co-occurrence of AD and autoimmune diseases. Our systematic review included 22 articles from PubMed describing the reciprocal association between AD and autoimmune diseases. Although not all the studies achieved statistically significant results, patients suffering from autoimmune diseases involving skin and intestinal mucosa, such as vitiligo, alopecia areata, celiac disease and inflammatory bowel diseases, showed a higher risk to have AD as comorbidity...
September 19, 2017: Journal of Dermatology
https://www.readbyqxmd.com/read/28921488/report-from-the-first-european-dermato-epidemiology-network-forum
#5
A Ascott, S M Langan, I García-Doval, M A Descalzo, S A J Schmidt, T Nijsten, L M Hollestein
The first European Dermato-Epidemiology Network (EDEN) forum was held on 30-31 March 2017 in Madrid, Spain. Dermatoepidemiology describes the study of causes, prevention, health services research and evaluation of interventions of skin diseases. EDEN aims to promote high-quality research, share expertise and facilitate collaboration. These aims were achieved during the EDEN forum by including a preconference course on skin cancer epidemiology; having excellent world-leading guest speakers on causality, quality of care, pharmacoepidemiology and missing data analysis; and including delegates who presented and discussed innovative research findings...
September 17, 2017: British Journal of Dermatology
https://www.readbyqxmd.com/read/28917451/postinflammatory-hyperpigmentation-a-comprehensive-overview-epidemiology-pathogenesis-clinical-presentation-and-noninvasive-assessment-technique
#6
REVIEW
Narumol Silpa-Archa, Indermeet Kohli, Suteeraporn Chaowattanapanit, Henry W Lim, Iltefat Hamzavi
Postinflammatory hyperpigmentation (PIH) commonly occurs after various endogenous and exogenous stimuli, especially in dark-skinned individuals. PIH is one of the most common complications of procedures performed using laser and other light sources. The severity of PIH is determined by the inherent skin color, degree and depth of inflammation, degree of dermoepidermal junction disruption, inflammatory conditions, and the stability of melanocytes, leading to epidermal and dermal melanin pigment deposition...
October 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/28916903/merkel-cell-carcinoma-epidemiology-pathogenesis-diagnosis-and-therapy
#7
REVIEW
Teresa Amaral, Ulrike Leiter, Claus Garbe
Merkel cell carcinoma (MCC) is a rare and aggressive skin cancer with a neuroendocrine phenotype. Incidence varies according to the geographic regions but is overall increasing. Different risk factors have been identified namely advanced age, immunosuppression, and ultraviolet light exposure. An association between MCC and polyomavirus infection is known. However, the exact mechanism that leads to carcinogenesis is yet to be fully understood. Surgery when feasible is the recommended treatment for localized disease, followed by adjuvant radiation or chemoradiation...
September 16, 2017: Reviews in Endocrine & Metabolic Disorders
https://www.readbyqxmd.com/read/28915699/biological-effects-and-epidemiological-consequences-of-arsenic-exposure-and-reagents-that-can-ameliorate-arsenic-damage-in-vivo
#8
REVIEW
Chinthalapally V Rao, Sanya Pal, Altaf Mohammed, Mudassir Farooqui, Mark P Doescher, Adam S Asch, Hiroshi Y Yamada
Through contaminated diet, water, and other forms of environmental exposure, arsenic affects human health. There are many U.S. and worldwide "hot spots" where the arsenic level in public water exceeds the maximum exposure limit. The biological effects of chronic arsenic exposure include generation of reactive oxygen species (ROS), leading to oxidative stress and DNA damage, epigenetic DNA modification, induction of genomic instability, and inflammation and immunomodulation, all of which can initiate carcinogenesis...
August 22, 2017: Oncotarget
https://www.readbyqxmd.com/read/28913989/patterns-of-inhalant-allergen-sensitization-and-geographical-variation-in-korean-adults-a-multicenter-retrospective-study
#9
Min Gyu Kang, Mi Yeong Kim, Woo Jung Song, Sujeong Kim, Eun Jung Jo, Seung Eun Lee, Jae Woo Kwon, Sang Min Lee, Chan Sun Park, Hye Kyung Park, Heung Woo Park, Yoon Seok Chang, Jaechun Lee, Young Min Lee, Young Koo Jee, Jong Myung Lee, Inseon S Choi, Sang Heon Cho
PURPOSE: Inhalant allergen sensitization is one of the major factors involved in the pathogenesis of allergic respiratory diseases. However, the sensitization is determined by interactions between genetic and environmental factors. Thus, testing panels of inhalant allergens may differ among geographical areas. Here we aimed to determine 10 common inhalant allergens in Korean adult patients with suspected respiratory allergies and to examine the variation between different geographical locations...
November 2017: Allergy, Asthma & Immunology Research
https://www.readbyqxmd.com/read/28913297/pyogenic-granuloma-a-retrospective-analysis-of-cases-treated-over-a-10-year
#10
Mun Geun Koo, Soo Hyang Lee, So Eun Han
BACKGROUND: Pyogenic granuloma (PG) is a benign vascular lesion of the mucosa and skin. Recent studies of the epidemiology of PG are rare. We aimed to retrospectively analyze characteristics of PG cases in South Korea. METHODS: We reviewed the medical records of 155 patients treated for PG between March 2005 and May 2014. The male-to-female ratio was 1:1.2 (70 males, 85 females). The mean age of patients was 35.3 years. RESULTS: A high occurrence was observed in the first and third decades in males, and the fourth to fifth decades in females...
March 2017: Arch Craniofac Surg
https://www.readbyqxmd.com/read/28904961/analysis-of-epidemiology-and-risk-factors-of-atopic-dermatitis-in-korean-children-and-adolescents-from-the-2010-korean-national-health-and-nutrition-examination-survey
#11
Kyung Suk Lee, In-Hwan Oh, Sun Hee Choi, Yeong-Ho Rha
BACKGROUND: Atopic dermatitis (AD) is a common chronic inflammatory skin disease, but only few studies involved samples of children and adolescents that are representative of the entire Korean population. This study aimed to estimate the prevalence and risk factors of AD among children and adolescents in Korea by using nationally representative data. METHODS: We used data from the fifth Korean National Health and Nutrition Examination Survey in 2010 and retrospectively evaluated 2,116 children and adolescents...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28901326/environmental-and-biological-monitoring-for-the-identification-of-main-exposure-determinants-in-vineyard-mancozeb-applicators
#12
Stefan Mandic-Rajcevic, Federico M Rubino, Eugenio Ariano, Danilo Cottica, Sara Neri, Claudio Colosio
Grapevine is a vulnerable crop to several fungal diseases often requiring the use of ethylenebisdithiocarbamate (EBDC) fungicides, such as mancozeb. This fungicide has been reported to have goitrogenic, endocrine disrupting, and possibly immunotoxic effects. The aim of this study was to assess workers' exposure in two scenarios of mancozeb application and analyse the main determinants of exposure in order to better understand their mechanism of influence. Environmental monitoring was performed using a modified Organisation for Economic Co-operation and Development (OECD) "patch" methodology and by hand-wash collection, while mancozeb's metabolite, ethylenethiourea (ETU), was measured in 24-h preexposure and postexposure urine samples...
September 13, 2017: Journal of Exposure Science & Environmental Epidemiology
https://www.readbyqxmd.com/read/28898965/late-boosting-phenomenon-in-tst-conversion-among-health-care-workers
#13
W H Farah, L E Breeher, R D Newcomb, M H Murad, A I S Vaughn, P T Hagen, R G Molella
Background: Available information is insufficient to guide determination of whether tuberculin skin test (TST) conversions of health care workers (HCWs) within 2 years of two-step testing are related to occupational exposures or to other causes, including late boosting. Aims: To describe the epidemiologic factors of TST conversion in HCWs, comparing early TST conversion (≤2 years after two-step testing) with late conversion to possibly distinguish late boosting phenomenon from occupational TST conversion...
August 1, 2017: Occupational Medicine
https://www.readbyqxmd.com/read/28895924/artificial-turf-contested-terrains-for-precautionary-public-health-with-particular-reference-to-europe
#14
Andrew Watterson
Millions of adults, children and teenagers use artificial sports pitches and playgrounds globally. Pitches are artificial grass and bases may be made up of crumb rubber from recycled tires or new rubber and sand. Player injury on pitches was a major concern. Now, debates about health focus on possible exposure and uptake of chemicals within pitch and base materials. Research has looked at potential risks to users from hazardous substances such as metals, volatile organic compounds, polycyclic aromatic hydrocarbons including benzo (a) (e) pyrenes and phthalates: some are carcinogens and others may be endocrine disruptors and have developmental reproductive effects...
September 12, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28895370/eosinophilic-esophagitis-current-evidence-based-diagnosis-and-treatment-in-children-and-adults
#15
Alfredo J Lucendo
Eosinophilic esophagitis (EoE) is a disease caused by an immune response to food antigens in contact with the esophageal mucosa that has arisen as a common disorder in current clinical practice. Its diagnosis is defined by the combination of symptoms of esophageal dysfunction and inflammation of the esophageal mucosa predominantly by eosinophils. Its chronic course and frequent progression to subepithelial fibrosis leading to strictures and narrow-caliber esophagus indicate the need for treatment. Information provided by recent clinical trials and systematic reviews allowed for the development of new clinical guidelines, endorsed by several European scientific societies...
September 11, 2017: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/28895117/updated-view-on-epidemiology-and-clinical-aspects-of-pilomatricoma-in-adults
#16
Geo Han, Ae-Ree Kim, Hae Jun Song, Chil Hwan Oh, Jiehyun Jeon
BACKGROUND: Clinically, pilomatricoma offers potential for a wide spectrum of differential diagnoses. It typically occurs in pediatric patients with the head being the most common location. A second peak of clinical presentation occurs in adults at age 50-65 years, suggesting a bimodal pattern of occurrence. OBJECTIVE: To investigate the clinical and epidemiological features of pilomatricoma in adults over 20 years old, as it is a common and frequently misdiagnosed tumor...
October 2017: International Journal of Dermatology
https://www.readbyqxmd.com/read/28892559/spirometry-adjusted-exhaled-nitric-oxide-increases-accuracy-for-assessment-of-asthma-control-in-children
#17
Carla Martins, Diana Silva, Milton Severo, João Rufo, Inês Paciência, Joana Madureira, Patrícia Padrão, Pedro Moreira, Luís Delgado, Eduardo Oliveira Fernandes, Henrique Barros, Pekka Malmberg, André Moreira
Spirometry and exhaled nitric oxide are two important complimentary tools to identify and assess asthma control in children. We aimed to determine the ability of a new suggested spirometry adjusted exhaled nitric oxide (NO) index in doing that. A random sample of 1602 schoolchildren were screened by a health questionnaire, skin-prick tests, spirometry with bronchodilation and exhaled NO. A total of 662 children were included with median (IQR) exhaled NO 11(14) ppb. ROC curves using exhaled NO equations from Malmberg, Kovesi and Buchvald, and spirometry adjusted exhaled NO values were applied to identify asthmatic children and uncontrolled asthma...
September 11, 2017: Pediatric Allergy and Immunology
https://www.readbyqxmd.com/read/28879496/tinea-corporis-caused-by-trichophyton-equinum-in-a-rider-and-review-of-the-literature
#18
Stefano Veraldi, Giovanni Genovese, Andrea Peano
BACKGROUND: Trichophyton equinum is a zoophilic dermatophyte usually causing ringworm in horses. Cases of skin infections in humans are very rare. CASE REPORT : ​We describe a case of tinea corporis caused by T. equinum on a buttock of a rider who often rode bareback with short trousers. CONCLUSION: Although T. equinum was considered in the past as a strict zoophilic dermatophyte, our case report confirms that it can cause dermatophytoses also in humans. A review of epidemiological and clinical features of human infections caused by T...
September 6, 2017: Infection
https://www.readbyqxmd.com/read/28876416/considerations-of-potential-vectors-and-animal-reservoirs-in-an-emerging-cutaneous-leishmaniasis-area-in-s%C3%A3-o-domingos-ranch-paran%C3%A3-state-in-southearn-brazil
#19
Norberto Assis Membrive, Flora Hisatugo, Thaís Gomes Verzignassi Silveira, Jorge Juarez Vieira Teixeira, Kárin Rosi Reinhold-Castro, Ueslei Teodoro
The aim of this study was to better understand the dynamics of Leishmania sand flies and reservoirs in São Domingos ranch, Arapongas municipality, Paraná State, an anthropic environment in an endemic area of cutaneous leishmaniasis (CL). Sand flies were collected in wild animal burrows, residences and in the forest, with Falcão light trap (FA), Shannon trap (SH) and quadrangular pyramidal trap (QP). The search for Leishmania was made on sand flies, biological samples of wild rodents and dogs using PCR and culture; while parasite direct search (DS) was carried out on animal skin lesions; infection of gold hamsters; and indirect immunofluorescence (IIF) test in dog blood samples...
September 4, 2017: Revista do Instituto de Medicina Tropical de São Paulo
https://www.readbyqxmd.com/read/28874315/hand-eczema-as-a-risk-factor-for-food-allergy-among-occupational-kitchen-workers
#20
Takafumi Minami, Yuma Fukutomi, Kiyoshi Sekiya, Akira Akasawa, Masami Taniguchi
BACKGROUND: An increasing number of studies in children is highlighting the importance of transdermal routes of exposure to food allergens through damaged skin in the pathogenesis of food allergies. However, data on this in adults are limited. A few case-series studies has documented development of food allergy among kitchen workers with hand eczema after direct contact exposure to foods. METHODS: To explore the significance of hand eczema as a risk factor for food allergies in adults at the epidemiological level, we performed a cross-sectional web-based questionnaire survey on kitchen workers whose exposures were classed as occupational (cooks and food handlers, n = 1592) or non-occupational (housewives, n = 1915)...
September 2, 2017: Allergology International: Official Journal of the Japanese Society of Allergology
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