keyword
https://read.qxmd.com/read/38525207/metabolic-syndrome-and-heart-transplantation-an-underestimated-risk-factor
#21
JOURNAL ARTICLE
Sandro Sponga, Igor Vendramin, Veronica Ferrara, Michela Marinoni, Giulia Valdi, Concetta Di Nora, Chiara Nalli, Giovanni Benedetti, Daniela Piani, Andrea Lechiancole, Maria Parpinel, Uberto Bortolotti, Ugolino Livi
Metabolic Syndrome (MetS), a multifactorial condition that increases the risk of cardio-vascular events, is frequent in Heart-transplant (HTx) candidates and worsens with immunosuppressive therapy. The aim of the study was to analyze the impact of MetS on long-term outcome of HTx patients. Since 2007, 349 HTx patients were enrolled. MetS was diagnosed if patients met revised NCEP-ATP III criteria before HTx, at 1, 5 and 10 years of follow-up. MetS was present in 35% of patients pre-HTx and 47% at 1 year follow-up...
2024: Transplant International
https://read.qxmd.com/read/38525163/exploring-the-diagnostic-value-of-high-frequency-ultrasound-technology-for-subcutaneous-lipohypertrophy-in-diabetes-patients-receiving-insulin-injections
#22
JOURNAL ARTICLE
Zhan-He Sun, Cheng-Hong Yu, Xin Wang
OBJECTIVE: This study aims to investigate the clinical application value of high-frequency ultrasound technology in diagnosing subcutaneous lipohypertrophy at insulin injection sites in diabetes patients. METHODS: All diabetes patients treated in our hospital from January 2022 to January 2023 were selected as the study subjects. The incidence of subcutaneous lipohypertrophy was calculated at the end of the study period. All patients were screened, and those meeting the inclusion criteria were registered, and basic data were collected...
2024: Diabetes, Metabolic Syndrome and Obesity
https://read.qxmd.com/read/38525162/a-prediction-model-of-preeclampsia-in-hyperglycemia-pregnancy
#23
JOURNAL ARTICLE
Yan Fang, Huali Liu, Yuan Li, Ji Cheng, Xia Wang, Bing Shen, Hongbo Chen, Qunhua Wang
PURPOSE: To investigate the risk factors associated with preeclampsia in hyperglycemic pregnancies and develop a predictive model based on routine pregnancy care. PATIENTS AND METHODS: The retrospective collection of clinical data was performed on 951 pregnant women with hyperglycemia, including those diagnosed with diabetes in pregnancy (DIP) and gestational diabetes mellitus (GDM), who delivered after 34 weeks of gestation at the Maternal and Child Health Hospital Affiliated to Anhui Medical University between January 2017 and December 2019...
2024: Diabetes, Metabolic Syndrome and Obesity
https://read.qxmd.com/read/38525161/metabolically-unhealthy-normal-weight-prevalence-and-associated-factors-in-an-adult-population-from-northwest-colombia
#24
JOURNAL ARTICLE
Julián Andrés López-Herrera, Adriana Nathaly Castillo, Jenny Elizabeth Ordoñez-Betancourth, Wilson de Jesús Martínez Quiroz, Luis Felipe Higuita-Gutiérrez, Milton F Suarez-Ortegon
BACKGROUND AND AIM: Individuals with a normal weight may have metabolic alterations at risk for chronic non-communicable diseases. The prevalence of this condition and associated factors have not been reported in Latin American populations. We aimed to estimate the presence and associated factors of Metabolically Unhealthy Normal Weight (MUNW) in adults from a public program for the control and prevention of chronic diseases in Medellín, Colombia. METHODS: Cross-sectional study...
2024: Diabetes, Metabolic Syndrome and Obesity
https://read.qxmd.com/read/38525160/erratum-sex-based-differences-and-risk-factors-for-comorbid-nonalcoholic-fatty-liver-disease-in-patients-with-bipolar-disorder-a-cross-sectional-retrospective-study-corrigendum
#25
(no author information available yet)
[This corrects the article DOI: 10.2147/DMSO.S428523.].
2024: Diabetes, Metabolic Syndrome and Obesity
https://read.qxmd.com/read/38524930/associations-of-alt-ast-a-marker-of-hepatosteatosis-with-pulse-rate-in-young-women-and-with-blood-pressure-in-middle-aged-women-independently-of-abdominal-fat-accumulation-and-insulin-resistance
#26
JOURNAL ARTICLE
Satomi Minato-Inokawa, Ayaka Tsuboi-Kaji, Mari Honda, Mika Takeuchi, Kaori Kitaoka, Miki Kurata, Bin Wu, Tsutomu Kazumi, Keisuke Fukuo
UNLABELLED: We examined whether alanine aminotransferase/aspartate aminotransferase (ALT/AST), a marker of hepatosteatosis, may be associated with a wider constellation of variables related to metabolic syndrome in Japanese women. Body fat and distribution, and metabolic syndrome-related variables were measured in 311 young and 148 middle-aged women. We had Pearson's correlation analysis and then stepwise multivariate linear regression analyses. In both middle-aged and young women, ALT/AST was associated with homeostasis model assessment insulin resistance (HOMA-IR), trunk/leg fat ratio and pulse rate...
April 2024: Diabetology International
https://read.qxmd.com/read/38524687/determinants-of-metabolic-syndrome-among-patients-receiving-anti-retro-viral-treatment-in-a-tertiary-hospital-central-ethiopia-unmatched-case-control-study
#27
JOURNAL ARTICLE
Godana Jarso, Haji Aman, Abebe Megerso
PURPOSE: Scaling up antiretroviral treatment (ART) reduces morbidity and mortality among people living with HIV/AIDS (PLHA). This success is challenged by the constellation of interrelated metabolic disorders such as metabolic syndrome (MetS). Given the changing ART regimens and schedules, increasing patient age and methodological limitations, existing evidence regarding the determinants of MetS remains inconclusive. Therefore, in the current study, we aimed to identify the determinants of MetS in patients receiving ART at a tertiary hospital in central Ethiopia...
2024: Therapeutics and Clinical Risk Management
https://read.qxmd.com/read/38523733/resistance-training-in-cardiovascular-diseases-a-review-on-its-effectiveness-in-controlling-risk-factors
#28
REVIEW
Arnengsih Nazir, Henhen Heryaman, Cep Juli, Azizah Ugusman, Januar Wibawa Martha, Marina Annette Moeliono, Nur Atik
Cardiovascular Disease (CVD), a term encompassing various disorders affecting the heart and blood vessels, includes coronary artery disease (CAD). CAD is primarily due to the development of atherosclerotic plaques that disrupt blood flow, oxygenation, and nutrient delivery to the myocardium. Risk factors contributing to CAD progression include smoking, hypertension, diabetes mellitus (DM), dyslipidaemia, and obesity. While aerobic exercise (AE) has shown promising results in controlling CVD risk factors, the impact of resistance training (RT) has not been extensively investigated...
2024: Integrated Blood Pressure Control
https://read.qxmd.com/read/38522165/metabolic-dysfunction-associated-steatotic-liver-disease-an-opportunity-for-collaboration-between-cardiology-and-hepatology
#29
REVIEW
Paolo Raggi, Jovana Milic, Marcella Manicardi, Felice Cinque, Mark G Swain, Giada Sebastiani, Giovanni Guaraldi
Altered metabolic function has many detrimental effects on the body that can manifest as cardiovascular and liver diseases. Traditional approaches to understanding and treating metabolic dysfunction-associated disorders have been organ-centered, leading to silo-type disease care. However, given the broad impact that systemic metabolic dysfunction has on the human body, approaches that simultaneously involve multiple medical specialists need to be developed and encouraged to optimize patient outcomes. In this review, we highlight how several of the treatments developed for cardiac care may have a beneficial effect on the liver and vice versa, suggesting that there is a need to target the disease process, rather than specifically target the cardiovascular or liver specific sequelae of metabolic dysfunction...
March 16, 2024: Atherosclerosis
https://read.qxmd.com/read/38520910/instruments-to-assess-diabetes-knowledge-skills-and-attitudes-of-people-living-with-diabetes-mellitus-a-cosmin-based-systematic-review
#30
REVIEW
Carla Assad Lemos, Thalita Zago Oliveira, João Paulo Alves Cunha, Daiane Vieira Medeiros Costa, Maria Olívia Barboza Zanetti, Rosana Aparecida Spadoti Dantas, Fabiana Rossi Varallo, Leonardo Régis Leira Pereira
AIMS: Since knowledge, skills, and attitudes influence the adherence to self-care behaviours, the purpose of this review was to identify available instruments that measure diabetes knowledge, skills or attitudes of people living with this health condition and to evaluate their measurement properties. METHODS: A systematic search was conducted in PubMed, EMBASE, SCOPUS, Web of Science and CINAHL databases. The methodological quality of the included studies was assessed by the Consensus-based Standards for the selection of health Measurement Instruments...
March 12, 2024: Diabetes & Metabolic Syndrome
https://read.qxmd.com/read/38520748/use-of-testosterone-replacement-therapy-to-treat-long-covid-related-hypogonadism
#31
JOURNAL ARTICLE
Alessandro Amodeo, Luca Persani, Marco Bonomi, Biagio Cangiano
SUMMARY: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can impair pituitary-gonadal axis and a higher prevalence of hypogonadism in post-coronavirus disease 2019 (COVID-19) patients compared with the general population has been highlighted. Here we report the first case of a patient affected with a long-COVID syndrome leading to hypogonadism and treated with testosterone replacement therapy (TRT) and its effects on clinical and quality of life (QoL) outcomes. We encountered a 62-year-old man who had been diagnosed with hypogonadotropic hypogonadism about 2 months after recovery from COVID-19 underwent a complete physical examination, general and hormonal blood tests, and self-reported questionnaires administration before and after starting TRT...
January 1, 2024: Endocrinology, Diabetes & Metabolism Case Reports
https://read.qxmd.com/read/38520608/research-advances-in-stem-cell-therapy-for-erectile-dysfunction
#32
REVIEW
Wei Wang, Ying Liu, Zuo-Bin Zhu, Kun Pang, Jing-Kai Wang, Jun Gu, Zhen-Bei Li, Jian Wang, Zhen-Duo Shi, Cong-Hui Han
Erectile dysfunction (ED) is a common clinical condition that mainly affects men aged over 40 years. Various causes contribute to the progression of ED, including pelvic nerve injury, diabetes, metabolic syndrome, age, Peyronie's disease, smoking, and psychological disorders. Current treatments for ED are limited to symptom relief and do not address the root cause. Stem cells, with their powerful ability to proliferate and differentiate, are a promising approach for the treatment of male ED and are gradually gaining widespread attention...
March 23, 2024: BioDrugs: Clinical Immunotherapeutics, Biopharmaceuticals and Gene Therapy
https://read.qxmd.com/read/38519973/combined-impact-of-alcohol-consumption-and-metabolic-syndrome-on-liver-dysfunction-in-an-elderly-chinese-population
#33
JOURNAL ARTICLE
Yanrong Zhao, Xiaoxue Yuan, Tianxiang Lin, Qing Yang, Xuewen Jiang, Song Yang, Yinwei Qiu
Alcohol consumption and metabolic syndrome(MetS), both prevalent in the general population, frequently co-occur. They are recognized as significant contributors to liver dysfunction, yet their combined effect is often challenging to delineate. This study delves into the compounding influence of alcohol consumption and metabolic disorder on liver dysfunction within an elderly demographic in Zhejiang Province, China. Our findings spotlight a heightened risk of liver dysfunction among females, younger individuals, rural dwellers, those with minimal educational attainment, single individuals, and those diagnosed with MetS...
March 23, 2024: Diabetology & Metabolic Syndrome
https://read.qxmd.com/read/38519188/wet-type-grinder-treated-okara-modulates-gut-microbiota-composition-and-attenuates-obesity-in-high-fat-fed-mice
#34
JOURNAL ARTICLE
Takao Nagano, Chihiro Watanabe, Eri Oyanagi, Hiromi Yano, Takumi Nishiuchi
Wet-type grinder (WG) is a nanofiber technology used to atomize dietary fiber-rich materials. WG-treated okara (WGO) exhibits high dispersion and viscosity similar to those of viscous soluble dietary fibers. Here, we studied the effect of WGO supplementation on obesity and gut microbiota composition in high-fat diet (HFD)-fed mice. WGO intake suppressed body weight gain and fat accumulation, improved glucose tolerance, lowered cholesterol levels, and prevented HFD-induced decrease in muscle mass. WGO supplementation also led to cecum enlargement, lower pH, and higher butyrate production...
April 2024: Food Research International
https://read.qxmd.com/read/38518956/establishment-optimization-and-validation-of-a-fluorescence-polarization-based-high-throughput-screening-assay-targeting-cathepsin-l-inhibitors
#35
JOURNAL ARTICLE
Wenwen Zhou, Baoqing You, Xiaomeng Zhao, Shuyi Si, Yan Li, Jing Zhang
Cathepsin L (CTSL), a lysosomal cysteine proteinase, is primarily dedicated to the metabolic turnover of intracellular proteins. It is involved in various physiological processes and contributes to pathological conditions such as viral infection, tumor invasion and metastasis, inflammatory status, atherosclerosis, renal disease, diabetes, bone diseases, and other ailments. The coronavirus disease 2019 (COVID-19), with its rapid global spread and significant mortality, has been a worldwide epidemic since the late 2019s...
March 20, 2024: SLAS Discovery
https://read.qxmd.com/read/38518450/association-of-platelet-to-lymphocyte-ratio-levels-with-the-risk-of-cardiac-adverse-events-in-people-with-type-2-diabetes-undergoing-percutaneous-coronary-intervention-a-large-scale-prospective-cohort-study
#36
JOURNAL ARTICLE
Yanjun Song, Zhangyu Lin, Jining He, Kongyong Cui, Chenxi Song, Rui Zhang, Zechen Liu, Tao An, Guofeng Gao, Ying Gao, Kefei Dou
BACKGROUND: The platelet-to-lymphocyte ratio (PLR), a promising inflammatory biomarker, contributes to the development of atherosclerosis and type 2 diabetes (T2D). Therefore, this study aimed to elucidate the importance of PLR in predicting adverse events in people undergoing percutaneous coronary intervention (PCI) with T2D. METHODS: We consecutively enrolled 8831 people who underwent PCI and divided them into four groups according to PLR and glycemic metabolic status (PLR-Low/High without T2D, PLR-Low/High with T2D)...
March 15, 2024: Diabetes & Metabolic Syndrome
https://read.qxmd.com/read/38517308/metabolic-syndrome-burden-determinants-and-treatment-status-in-an-urban-slum-resettlement-colony-in-delhi-india
#37
JOURNAL ARTICLE
Shivani Rao, Saurav Basu, Kajal Nandi, M M Singh, Heena Lalwani, Vansh Maheshwari, Amod Borle, Nandini Sharma
BACKGROUND: Metabolic syndrome (MetS) in low-resource settings contributes to accentuated risk of cardiovascular disease, including stroke. The study objective was to estimate the prevalence, determinants and treatment status of MetS in an urban slum resettlement population in Delhi, India. METHODS: This study was conducted from February to May 2023. Multiphase sampling was conducted with 1910 individuals screened for abdominal obesity (AO), with 996 detected as having AO, of which, 400 were selected by simple random sampling and further evaluated for triglycerides (TGs), high-density lipoprotein (HDL) and fasting glucose levels...
March 22, 2024: International Health
https://read.qxmd.com/read/38516881/-impact-of-self-reported-periodontal-status-on-oral-health-related-quality-of-life-in-adult-population-with-type-2-diabetes-from-mexico-city
#38
JOURNAL ARTICLE
José Armando Falcón-Flores, María Eugenia Jiménez-Corona, Sergio Flores-Hernández, Marisela Vázquez-Duran, Aida Jiménez-Corona
OBJECTIVE: Periodontitis ranks sixth as a type 2 diabetes (T2D) complication. According to its severity, it may cause pain, discomfort and tooth loss. The aim of this study was to evaluate the impact of self-reported periodontal status on the Oral Health Related Quality of Life (OHRQoL) of people with T2D. METHODS: A cross-sectional study was conducted involving seventy-nine adults with T2D who visited the Metabolic Syndrome clinic at the Cosío Villegas National Institute of Respiratory Diseases in Mexico City between August and November 2010...
March 14, 2024: Revista Española de Salud Pública
https://read.qxmd.com/read/38516814/review-article-new-developments-in-biomarkers-and-clinical-drug-development-in-alpha-1-antitrypsin-deficiency-related-liver-disease
#39
REVIEW
Rohit Loomba, Ginger Clark, Jeff Teckman, Veeral Ajmera, Cynthia Behling, Mark Brantly, David Brenner, Jeanine D'Armiento, Michael W Fried, Janani S Iyer, Mattias Mandorfer, Don C Rockey, Monica Tincopa, Raj Vuppalanchi, Zobair Younossi, Aleksander Krag, Alice M Turner, Pavel Strnad
BACKGROUND: Alpha-1 antitrypsin liver disease (AATLD) occurs in a subset of patients with alpha-1 antitrypsin deficiency. Risk factors for disease progression and specific pathophysiologic features are not well known and validated non-invasive assessments for disease severity are lacking. Currently, there are no approved treatments for AATLD. AIMS: To outline existing understanding of AATLD and to identify knowledge gaps critical to improving clinical trial design and development of new treatments...
March 22, 2024: Alimentary Pharmacology & Therapeutics
https://read.qxmd.com/read/38515400/metabolic-syndrome-and-cardiovascular-disease-in-cancer-survivors
#40
JOURNAL ARTICLE
Kensuke Ueno, Hidehiro Kaneko, Yuta Suzuki, Akira Okada, Satoshi Matsuoka, Katsuhito Fujiu, Nobuaki Michihata, Taisuke Jo, Norifumi Takeda, Hiroyuki Morita, Kentaro Kamiya, Junya Ako, Koichi Node, Hideo Yasunaga, Issei Komuro
BACKGROUND: The risk of subsequent cardiovascular disease (CVD) is high in cancer survivors. Although metabolic syndrome is an established risk factor for CVD, its association with cancer survivors has not yet been established. This study aimed to clarify whether metabolic syndrome is associated with subsequent CVD risk in patients with cancer using a nationwide epidemiological dataset. METHODS: We retrospectively analysed 53 510 patients with a history of breast, colorectal, or stomach cancer, which is reportedly a major site for developing cancer in Japan...
March 22, 2024: Journal of Cachexia, Sarcopenia and Muscle
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