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Lymphoedema

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https://www.readbyqxmd.com/read/29916444/information-technology-in-morbidity-management-of-human-lymphatic-filariasis-a-promising-tool-in-global-programme-for-elimination-of-lymphatic-filariasis
#1
R Renuka Devi, V Raju
Background & objectives: India is a signatory to the 1997 World Health Assembly resolutions on lymphatic fila- riasis, and other neglected tropical diseases, and supports global elimination of lymphatic filariasis by 2020. The global programme to eliminate lymphatic filariasis (GPELF) has two main components, viz. interrupting transmission of LF through mass drug administration; and managing morbidity and preventing disability. Consorted efforts by the Public Health Department in Tamil Nadu state (India) for elimination of LF was launched in the year 1997 concentrating on both the components of the programme...
January 2018: Journal of Vector Borne Diseases
https://www.readbyqxmd.com/read/29906199/lymphoedema-support-network-update
#2
Karen Friett
No abstract text is available yet for this article.
April 1, 2018: British Journal of Community Nursing
https://www.readbyqxmd.com/read/29906197/mobiderm-autofit-an-adjustable-sleeve-that-enables-patients-to-self-manage-lymphoedema
#3
Marie Todd, Charlotte Stubbs, Stacy Pugh
Lymphoedema can result in debilitating physical and psychosocial morbidity and when combined with other chronic comorbidity, often requires holistic, specialist management that encompasses all the complex and compounding problems. Self-care is an integral component of any treatment strategy, however, the patient must be fully prepared and ongoing support should be provided. Self-care consists of managing the symptoms of lymphoedema but should include other fundamental aspects of healthy living, for example, maintaining a healthy weight and activity levels...
April 1, 2018: British Journal of Community Nursing
https://www.readbyqxmd.com/read/29906195/my-road-to-discovering-lymphoedema-and-beyond
#4
Trevor Walton
No abstract text is available yet for this article.
April 1, 2018: British Journal of Community Nursing
https://www.readbyqxmd.com/read/29896974/a-novel-mutation-in-the-conserved-sequence-of-vascular-endothelial-growth-factor-receptor-3-leads-to-primary-lymphoedema
#5
Ting Dai, Bohan Li, Bo He, Liwei Yan, Liqiang Gu, Xiaolin Liu, Jian Qi, Ping Li, Xiang Zhou
Objective To investigate whether lymphoedema in a Chinese family showed the hereditary and clinical characteristics of Milroy disease, an autosomal dominant form of congenital lymphoedema, typically characterized by chronic lower limb tissue swelling due to abnormal lymphatic vasculature development, and to perform mutational analyses of vascular endothelial growth factor receptor ( VEGFR)3. Methods Individuals from a three-generation family affected by congenital lymphoedema were clinically assessed for Milroy disease...
January 1, 2018: Journal of International Medical Research
https://www.readbyqxmd.com/read/29869912/is-there-an-inequity-of-uk-lymphoedema-service-provision
#6
Ioan Humphreys
No abstract text is available yet for this article.
June 2, 2018: British Journal of Community Nursing
https://www.readbyqxmd.com/read/29866673/prenatal-thoraco-amniotic-chest-drain-insertion-to-manage-a-case-of-fetal-hydrops-secondary-to-foxc2
#7
Nidhi Gulati, Rachel Katie Morris, Denise Williams, Mark David Kilby
Lymphoedema-distichiasis is an inherited autosomal dominant disorder of the lymphatic system. Rarely, it is associated with fetal hydrops; the risk and severity of which increases with successive generations. The causative gene is a member of the forkhead transcription factor family ( FOXC2 ). We describe a fetus presenting with early-onset, rapidly progressing body wall oedema, bilateral pleural effusions and a pericardial effusion in a mother with known FOXC2 mutation. First trimester chorionic villus sampling confirmed FOXC2 mutation in the fetus when there was only a large nuchal translucency...
June 4, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29857904/neuromuscular-taping-reduces-blood-pressure-in-systemic-arterial-hypertension
#8
M Shah, P O O Julu, J A Monro, J Coutinho, C Ijeh, B K Puri
Systemic arterial hypertension, a well-known cause of morbidity, is associated with dysfunction of the autonomic nervous system. Neuromuscular taping (also known as kinesio taping, medical taping and Vendje neuromuscular) allows movement and muscle activity to treat pain, muscle disorders and lymphoedema, in which its mode of action may involve muscular stimulation leading to increased local blood circulation or stimulating dermatological, muscular and fascial structures with a form of passive massage. We hypothesised that neuromuscular taping may reduce blood pressure in systemic arterial hypertension...
July 2018: Medical Hypotheses
https://www.readbyqxmd.com/read/29804748/first-successful-experimental-implantation-of-a-drainage-device-to-reduce-lymphoedema-in-a-rat-lymphoedema-model
#9
Valentina Triacca, Marco Pisano, Claudia Lessert, Benoit Petit, Karima Bouzourene, Aimable Nahimana, Marie-Catherine Vozenin, Nikolaos Stergiopulos, Melody A Swartz, Lucia Mazzolai
OBJECTIVE/BACKGROUND: Despite recent advances in pharmacological research and microsurgery, lymphoedema remains an incurable disease that deeply affects quality of life. There is an urgent need for innovative approaches to restore continuous lymph flow in affected tissues. To this end, the efficacy of a subcutaneously implanted draining device in reducing lymphoedema volume in a rat hindlimb lymphoedema model was tested. METHODS: A rat model of chronic lymphoedema was developed by surgical removal of popliteal and inguinal lymph nodes, followed by irradiation...
May 24, 2018: European Journal of Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/29799792/woundcare4heroes-steps-in-to-help-veterans-with-lymphoedema
#10
Rachel Masker
No abstract text is available yet for this article.
June 1, 2018: British Journal of Community Nursing
https://www.readbyqxmd.com/read/29799780/is-there-an-inequity-of-uk-lymphoedema-service-provision
#11
Ioan Humphreys
No abstract text is available yet for this article.
June 2, 2018: British Journal of Community Nursing
https://www.readbyqxmd.com/read/29774284/rapid-integrated-clinical-survey-to-determine-prevalence-and-co-distribution-patterns-of-lymphatic-filariasis-and-onchocerciasis-in-a-loa-loa-co-endemic-area-the-angolan-experience
#12
Miguel Brito, Rossely Paulo, Pedro Van-Dunem, António Martins, Thomas R Unnasch, Robert J Novak, Benjamin Jacob, Michelle C Stanton, David H Molyneux, Louise A Kelly-Hope
The Republic of Angola is a priority country for onchocerciasis and lymphatic filariasis (LF) elimination, however, the co-distribution of the filarial parasite Loa loa (loiasis) is a significant impediment, due to the risk of severe adverse events (SAEs) associated with ivermectin used in mass drug administration (MDA) campaigns. Angola has a high risk loiasis zone identified in Bengo Province where alternative interventions may need to be implemented; however, the presence and geographical overlap of the three filarial infections/diseases are not well defined...
August 2017: Parasite Epidemiology and Control
https://www.readbyqxmd.com/read/29773516/lymphoedema-management-to-prevent-acute-dermatolymphangioadenitis-in-podoconiosis-in-northern-ethiopia-golbet-a-pragmatic-randomised-controlled-trial
#13
Henok Negussie, Meseret Molla, Moses Ngari, James A Berkley, Esther Kivaya, Patricia Njuguna, Greg Fegan, Abreham Tamiru, Abebe Kelemework, Trudie Lang, Melanie J Newport, Andy McKay, Fikre Enquoselassie, Gail Davey
BACKGROUND: Podoconiosis (also known as endemic, non-filarial elephantiasis) affects about 4 million subsistence farmers in tropical Africa. Poor awareness of the condition and inadequate evidence for the efficacy of treatment mean that no government in an endemic country yet offers lymphoedema management for patients with podoconiosis. Among patients with filarial lymphoedema, trials suggest that limb care is effective in reducing the most disabling sequelae: episodes of acute dermatolymphangioadenitis...
May 14, 2018: Lancet Global Health
https://www.readbyqxmd.com/read/29771349/study-of-lymphoedema-of-non-filarial-origin-in-the-northwest-region-of-cameroon-spatial-distribution-profiling-of-cases-and-socio-economic-aspects-of-podoconiosis
#14
Samuel Wanji, Jonas A Kengne-Ouafo, Kebede Deribe, Ayok M Tembei, Abdel Jelil Njouendou, Dizzel Bita Tayong, David D Sofeu-Feugaing, Fabrice R Datchoua-Poutcheu, Jorge Cano, Emanuele Giorgi, Yolande F Longang-Tchounkeu, Peter A Enyong, Melanie J Newport, Gail Davey
Background: Although podoconiosis is endemic in Cameroon, little is known about its epidemiology and spatial distribution. Methods: This cross-sectional, population-based study enrolled all adults (≥15 y) residing in the districts of the northwest region of Cameroon for 10 or more years. Participants were interviewed and had a physical examination. The study outcomes were prevalence estimates of lymphoedema and podoconiosis. House-to-house screening was conducted by Community Health Implementers (CHIs)...
May 16, 2018: International Health
https://www.readbyqxmd.com/read/29724903/natural-history-of-gata2-deficiency-in-a-survey-of-79-french-and-belgian-patients
#15
Jean Donadieu, Marie Lamant, Claire Fieschi, Flore Sicre de Fontbrune, Aurélie Caye, Marie Ouachee, Blandine Beaupain, Jacinta Bustamante, Hélène A Poirel, Bertrand Isidor, Eric Van Den Neste, Antoine Neel, Stanislas Nimubona, Fabienne Toutain, Vincent Barlogis, Nicolas Schleinitz, Thierry Leblanc, Pierre Rohrlich, Felipe Suarez, Dana Ranta, Wahid Abou Chahla, Bénédicte Bruno, Louis Terriou, Sylvie Francois, Bruno Lioure, Guido Ahle, Françoise Bachelerie, Claude Preudhomme, Eric Delabesse, Hélène Cavé, Christine Bellanné-Chantelot, Marlène Pasquet
Heterozygous germline GATA2 mutations strongly predispose to leukaemia, immunodeficiency, and/or lymphoedema. We now describe a series of 79 patients (53 families) diagnosed since 2011, compiling all patients in France and Belgium, with a follow up of 2249 patients/years. Median age at first clinical symptoms was 18.6 years (range, 0-61 years). Severe infectious diseases (mycobacteria, fungus, and human papilloma virus) and haematological malignancies were the most common first manifestations. The probability of remaining symptom-free was 8% at 40 years old...
May 3, 2018: Haematologica
https://www.readbyqxmd.com/read/29723583/psychometric-development-of-the-upper-limb-lymphoedema-questionnaire-demonstrated-the-patient-reported-outcome-measure-to-be-a-robust-measure-for-breast-cancer-related-lymphoedema
#16
Angela E Williams, Frances Rapport, Ian T Russell, Hayley A Hutchings
OBJECTIVE: To develop and undertake initial validation of a patient-reported outcome measure (PROM) to assess health-related quality of life in patients with breast cancer-related upper limb lymphedema (ULL). STUDY DESIGN AND SETTING: We developed and validated the Upper Limb Lymphedema Quality of Life (ULLQoL) scale in two stages: devising the items and pre-testing with patients and clinicians; longitudinal validation to test its psychometric properties - underlying dimensions, internal consistency, test-retest reliability, construct validity, and responsiveness...
April 30, 2018: Journal of Clinical Epidemiology
https://www.readbyqxmd.com/read/29704765/lymphatic-endothelial-progenitor-cells-origins-and-roles-in-lymphangiogenesis
#17
REVIEW
Jan Kazenwadel, Natasha L Harvey
How are lymphatic vessels built? What are the sources of progenitor cells employed to construct lymphatic vessels during embryogenesis and in pathological situations? Are lymphatic vessels in different tissues built the same way? These questions have been highly topical and actively debated in the field of lymphangiogenesis research for more than 100 years. While embryonic veins and cells of mesenchymal origin have been recognised as sources of embryonic lymphatic endothelial cells for many years, recent advances in technology have revealed the existence of additional sources of lymphatic endothelial cells important for embryonic lymphangiogenesis...
April 25, 2018: Current Opinion in Immunology
https://www.readbyqxmd.com/read/29674402/cutaneous-lymphangitis-carcinomatosa-made-cervicofacial-oedema-intractable-in-a-patient-with-superior-vena-cava-syndrome
#18
Eriko Kashihara, Osamu Kanai, Misato Okamura, Tadashi Mio
Cutaneous lymphangitis carcinomatosa (CLC) is a rare form of cutaneous metastasis that causes lymphoedema and various eruptions. We report a case of lung cancer with CLC that caused both superior vena cava (SVC) stenosis and cervicofacial oedema, suggestive of SVC syndrome. A 64-year-old woman with lung adenocarcinoma presented with cervicofacial oedema and erythema, followed by severe dyspnoea 2 months after four cycles of carboplatin, pemetrexed and bevacizumab triplet therapy. Although chest CT indicated SVC stenosis, cervicofacial oedema remained despite treating the SVC stenosis via balloon dilation...
April 19, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29663122/worldwide-assessment-of-healthcare-personnel-dealing-with-lymphoedema
#19
Henrike Schulze, Marisa Nacke, Christoph Gutenbrunner, Catarina Hadamitzky
BACKGROUND: Lymphoedema is a pandemic with about 250 million people suffering from this condition worldwide. Lymphatic diseases have considerable public health significance, but yet few professionals are specialised in their management causing a substantial burden on health resources. AIMS AND OBJECTIVES: This study aims to give an overview of the approximate number of medical professionals, professional societies, institutions and companies dealing with lymphoedema in various countries...
April 16, 2018: Health Economics Review
https://www.readbyqxmd.com/read/29587549/the-importance-of-the-rehabilitation-program-following-an-internal-hemipelvectomy-and-reconstruction-with-limb-salvage-gait-analysis-and-outcomes-a-case-study
#20
Adele Wingrave, Hannah Jarvis
BACKGROUND: Chondrosarcomas account for approximately 20% of bone sarcomas, with the most common site being the lower limb. Hemipelvectomies that involve hindquarter amputation have previously been the treatment of choice for pelvic tumors. However, with advances in chemotherapy, radiotherapy, imaging and surgical techniques more patients are now being treated with limb salvage surgery. The rehabilitation outcomes following an internal hemipelvectomy have not been well identified and there is currently little, if any, gait analysis data on rehabilitation following hemipelvectomy in limb salvage patients...
March 28, 2018: Disability and Rehabilitation
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