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Pneumonia vascular access

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https://www.readbyqxmd.com/read/29061707/cell-invasion-and-pyruvate-oxidase-derived-h2o2-are-critical-for-streptococcus-pneumoniae-mediated-cardiomyocyte-killing
#1
Terry Brissac, Anukul T Shenoy, LaDonna A Patterson, Carlos J Orihuela
Streptococcus pneumoniae (Spn, the pneumococcus) is the leading cause of community-acquired pneumonia and is now recognized to be a direct contributor to adverse acute cardiac events. During invasive pneumococcal disease, Spn can gain access to the myocardium, kill cardiomyocytes, and form bacteria-filled "microlesions" causing considerable acute and long-lasting cardiac damage. While the molecular mechanisms responsible for bacterial translocation into the heart have been elucidated, the initial interactions of heart-invaded Spn with cardiomyocytes remain unclear...
October 23, 2017: Infection and Immunity
https://www.readbyqxmd.com/read/28922054/economic-burden-of-pneumococcal-infections-in-children-under-5%C3%A2-years-of-age
#2
Mehmet Ceyhan, Yasemin Ozsurekci, Kubra Aykac, Basak Hacibedel, Egemen Ozbilgili
The present study aimed to determine the cost of childhood pneumococcal infections under 5 years of age and to provide further data for future health economy studies. Electronic medical records of children diagnosed with meningitis caused by S. pneumoniae and all-cause pneumonia, and acute otitis media (AOM) between January 2013-April 2014 were retrospectively evaluated. Direct costs for the treatments of hospitalized patients (pneumonia and pneumococcal meningitis) including costs of healthcare services consisted of costs of hospital bed, examination, laboratory analyses, scanning methods, consultation, vascular access procedures, and infusion and intravenous treatments...
September 18, 2017: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/28777716/research-priorities-in-subspecialty-palliative-care-policy-initiatives
#3
Lynn F Reinke, Diane E Meier
Palliative care demonstrably improves quality of life for the seriously ill in a manner that averts preventable health crises and their associated costs. Because of these outcomes, palliative care is now broadening its reach beyond hospitals, and hospice care for those near death, to patients and their families living in the community with chronic multimorbidities that have uncertain or long expected survival. In this article, we address research needed to enable policies supportive of palliative care access and quality, including changes in regulatory, accreditation, financing, and training approaches in the purview of policy makers...
August 2017: Journal of Palliative Medicine
https://www.readbyqxmd.com/read/28238919/characteristics-management-and-outcomes-of-surgically-treated-arteriovenous-fistula-aneurysm-in-patients-on-regular-hemodialysis
#4
Hassan Al-Thani, Ayman El-Menyar, Noora Al-Thani, Mohammad Asim, Ahmed Hussein, Ahmed Sadek, Ahmed Sharaf, Amr Fares
BACKGROUND: To investigate the clinical characteristics, surgical interventions, and outcomes of arteriovenous fistula (AVF) aneurysms, we retrospectively analyzed patients on regular hemodialysis (HD). METHODS: We conducted a cohort study of all patients with HD access who presented with AVF aneurysms and underwent operative procedures over a 11-year period. Patients' demographics, comorbidities, vascular access characteristics, management of aneurysms, complications, and outcomes were analyzed...
May 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28027819/mortality-and-readmission-of-outcomes-after-discharge-from-the-surgical-intensive-care-unit-to-long-term-acute-care-hospitals
#5
Michelle C Nguyen, David S Strosberg, Teresa S Jones, Ankur Bhakta, Edward L Jones, Michael R Lyaker, Cindy A Byrd, Carly Sobol, Daniel S Eiferman
BACKGROUND: Patients with prolonged hospitalizations in the surgical intensive care unit often have ongoing medical needs that require further care at long-term, acute-care hospitals upon discharge. Setting expectations for patients and families after protracted operative intensive care unit hospitalization is challenging, and there are limited data to guide these conversations. The purpose of this study was to determine patient survival and readmission rates after discharge from the surgical intensive care unit directly to a long-term, acute-care hospital...
May 2017: Surgery
https://www.readbyqxmd.com/read/27630843/microbiology-of-non-tunnelled-catheter-related-infections
#6
Shefali Gupta, Shrikara P Mallya, Ashok Bhat, Shrikala Baliga
INTRODUCTION: Aerobic bacterial infections often complicate vascular access in patients receiving haemodialysis, leading to Catheter-Related Blood Stream Infections (CRBSI). Various studies report Gram - positive bacteria, Staphylococcus aureus (S. aureus) in particular, as the most common aetiologic agent. Studies on microbiological analysis in this subset of population from India are very few. AIM: To examine clinical and bacteriological profiles of haemodialysis patients developing CRBSI, the antibiotic susceptibility of the bacteria isolated from these patients and determine nasal carriage of S...
July 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27604617/12th-winfocus-world-congress-on-ultrasound-in-emergency-and-critical-care
#7
Yahya Acar, Onur Tezel, Necati Salman, Erdem Cevik, Margarita Algaba-Montes, Alberto Oviedo-García, Mayra Patricio-Bordomás, Mustafa Z Mahmoud, Abdelmoneim Sulieman, Abbas Ali, Alrayah Mustafa, Ihab Abdelrahman, Mustafa Bahar, Osama Ali, H Lester Kirchner, Gregor Prosen, Ajda Anzic, Paul Leeson, Maryam Bahreini, Fatemeh Rasooli, Houman Hosseinnejad, Gabriel Blecher, Robert Meek, Diana Egerton-Warburton, Edina Ćatić Ćuti, Stanko Belina, Tihomir Vančina, Idriz Kovačević, Nadan Rustemović, Ikwan Chang, Jin Hee Lee, Young Ho Kwak, Do Kyun Kim, Chi-Yung Cheng, Hsiu-Yung Pan, Chia-Te Kung, Ela Ćurčić, Ena Pritišanac, Ivo Planinc, Marijana Grgić Medić, Radovan Radonić, Abiola Fasina, Anthony J Dean, Nova L Panebianco, Patricia S Henwood, Oliviero Fochi, Moreno Favarato, Ezio Bonanomi, Ivan Tomić, Youngrock Ha, Hongchuen Toh, Elizabeth Harmon, Wilma Chan, Cameron Baston, Gail Morrison, Frances Shofer, Angela Hua, Sharon Kim, James Tsung, Isa Gunaydin, Zeynep Kekec, Mehmet Oguzhan Ay, Jinjoo Kim, Jinhyun Kim, Gyoosung Choi, Dowon Shim, Ji-Han Lee, Jana Ambrozic, Katja Prokselj, Miha Lucovnik, Gabrijela Brzan Simenc, Asta Mačiulienė, Almantas Maleckas, Algimantas Kriščiukaitis, Vytautas Mačiulis, Andrius Macas, Sharad Mohite, Zoltan Narancsik, Hugon Možina, Sara Nikolić, Jan Hansel, Rok Petrovčič, Una Mršić, Simon Orlob, Markus Lerchbaumer, Niklas Schönegger, Reinhard Kaufmann, Chun-I Pan, Chien-Hung Wu, Sarah Pasquale, Stephanie J Doniger, Sharon Yellin, Gerardo Chiricolo, Maja Potisek, Borut Drnovšek, Boštjan Leskovar, Kristine Robinson, Clara Kraft, Benjamin Moser, Stephen Davis, Shelley Layman, Yusef Sayeed, Joseph Minardi, Irmina Sefic Pasic, Amra Dzananovic, Anes Pasic, Sandra Vegar Zubovic, Ana Godan Hauptman, Ana Vujaklija Brajkovic, Jaksa Babel, Marina Peklic, Vedran Radonic, Luka Bielen, Peh Wee Ming, Nur Hafiza Yezid, Fatahul Laham Mohammed, Zainal Abidin Huda, Wan Nasarudin Wan Ismail, W Yus Haniff W Isa, Hashairi Fauzi, Praveena Seeva, Mohd Zulfakar Mazlan
A1 Point-of-care ultrasound examination of cervical spine in emergency departmentYahya Acar, Onur Tezel, Necati SalmanA2 A new technique in verifying the placement of a nasogastric tube: obtaining the longitudinal view of nasogastric tube in addition to transverse view with ultrasoundYahya Acar, Necati Salman, Onur Tezel, Erdem CevikA3 Pseudoaneurysm of the femoral artery after cannulation of a central venous line. Should we always use ultrasound in these procedures?Margarita Algaba-Montes, Alberto Oviedo-García, Mayra Patricio-BordomásA4 Ultrasound-guided supraclavicular subclavian vein catheterization...
September 2016: Critical Ultrasound Journal
https://www.readbyqxmd.com/read/27566273/paediatric-staphylococcus-aureus-bacteraemia-a-single-centre-retrospective-cohort
#8
Jessica C Roediger, Alexander C Outhred, Bruce Shadbolt, Philip N Britton
AIM: We aimed to describe the clinical epidemiology of Staphylococcus aureus bacteraemia (SAB) at a large, tertiary/quaternary children's hospital in Australia. METHODS: We performed a retrospective chart review of SAB cases at the Children's Hospital at Westmead (CHW) over 5 years; 2006-2011. We compared frequency, clinical profile and outcomes of SAB with published data from CHW; 1994-1998. We compared health-care associated with community-associated (HCA-SAB and CA-SAB; defined epidemiologically) and methicillin-resistant with methicillin susceptible S...
February 2017: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/27053221/surgical-management-of-symptomatic-brain-stem-cavernoma-in-a-developing-country-technical-difficulties-and-outcome
#9
Ahmed Farhoud, Hisham Aboul-Enein
Brain stem cavernomas (BSCs) are angiographically occult vascular malformations in an intricate location. Surgical excision of symptomatic BSCs represents a neurosurgical challenge especially in developing countries. We reviewed the clinical data and surgical outcome of 24 consecutive cases surgically treated for brain stem cavernoma at the Neurosurgery Department, Alexandria University, between 2006 and 2014. All patients were followed up for at least 12 months after surgery and the mean follow-up period was 45 months...
July 2016: Neurosurgical Review
https://www.readbyqxmd.com/read/26090668/the-role-of-exos-in-dissemination-of-pseudomonas-aeruginosa-during-pneumonia
#10
Stephanie M Rangel, Maureen H Diaz, Claire A Knoten, Angelica Zhang, Alan R Hauser
Hospital-acquired pneumonia is associated with high rates of morbidity and mortality, and dissemination to the bloodstream is a recognized risk factor for particularly poor outcomes. Yet the mechanism by which bacteria in the lungs gain access to the bloodstream remains poorly understood. In this study, we used a mouse model of Pseudomonas aeruginosa pneumonia to examine this mechanism. P. aeruginosa uses a type III secretion system to deliver effector proteins such as ExoS directly into the cytosol of eukaryotic cells...
June 2015: PLoS Pathogens
https://www.readbyqxmd.com/read/26005388/central-venous-catheter-as-vascular-approach-for-hemodialysis-our-experiences
#11
Verica Misanovic, Fedzat Jonuzi, Dusko Anic, Mirza Halimic, Samra Rahmanovic
INTRODUCTION: Application of a central venous catheter (CVC), as a temporary or permanent vascular access for hemodialysis, has been continuous practice at the Sarajevo Pediatric Clinic, Department of Pediatric Intensive Care. The main goal of the article is to present our experiences with central venous catheters in the treatment of these patients. MATERIAL AND METHODS: In the period from January 2009 to December 2014 a total of 41 patients were treated and a total of 56 catheters were placed...
April 2015: Materia Socio-medica
https://www.readbyqxmd.com/read/25741606/catheterization-of-the-carotid-artery-and-jugular-vein-to-perform-hemodynamic-measures-infusions-and-blood-sampling-in-a-conscious-rat-model
#12
Jing Feng, Yvonne Fitz, Yan Li, Melinda Fernandez, Irene Cortes Puch, Dong Wang, Stephanie Pazniokas, Brandon Bucher, Xizhong Cui, Steven B Solomon
The success of a small animal model to study critical illness is, in part, dependent on the ability of the model to simulate the human condition. Intra-tracheal inoculation of a known amount of bacteria has been successfully used to reproduce the pathogenesis of pneumonia which then develops into sepsis. Monitoring hemodynamic parameters and providing standard clinical treatment including infusion of antibiotics, fluids and drugs to maintain blood pressure is critical to simulate routine supportive care in this model but to do so requires both arterial and venous vascular access...
2015: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/25432552/ten-good-reasons-to-practice-ultrasound-in-critical-care
#13
REVIEW
Daniel Lichtenstein, Simon van Hooland, Paul Elbers, Manu L N G Malbrain
Over the past decade, critical care ultrasound has gained its place in the armamentarium of monitoring tools. A greater understanding of lung, abdominal, and vascular ultrasound plus easier access to portable machines have revolutionised the bedside assessment of our ICU patients. Because ultrasound is not only a diagnostic test, but can also be seen as a component of the physical exam, it has the potential to become the stethoscope of the 21st century. Critical care ultrasound is a combination of simple protocols, with lung ultrasound being a basic application, allowing assessment of urgent diagnoses in combination with therapeutic decisions...
November 2014: Anaesthesiology Intensive Therapy
https://www.readbyqxmd.com/read/23998786/early-clinical-outcome-of-aortic-transcatheter-valve-in-valve-implantation-in-the-nordic-countries
#14
Leo Ihlberg, Henrik Nissen, Niels-Erik Nielsen, Andreas Rück, Rolf Busund, Kaj-Erik Klaarborg, Lars Soendergaard, Jan Harnek, Heikki Miettinen, Markku Eskola, Alexander Wahba, Mika Laine
OBJECTIVE: Transcatheter valve-in-valve implantation has emerged as an option, in addition to reoperative surgical aortic valve replacement, to treat failed biologic heart valve substitutes. However, the clinical experience with this approach is still limited. We report the comprehensive experience of transcatheter valve-in-valve implantation in the Nordic countries from May 2008 to January 2012. METHODS: A total of 45 transcatheter aortic valve-in-valve implantations were performed during the study period in 11 centers...
November 2013: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/23964088/invasive-methicillin-resistant-staphylococcus-aureus-infections-among-patients-on-chronic-dialysis-in-the-united-states-2005-2011
#15
Duc B Nguyen, Fernanda C Lessa, Ruth Belflower, Yi Mu, Matthew Wise, Joelle Nadle, Wendy M Bamberg, Susan Petit, Susan M Ray, Lee H Harrison, Ruth Lynfield, Ghinwa Dumyati, Jamie Thompson, William Schaffner, Priti R Patel
BACKGROUND: Approximately 15 700 invasive methicillin-resistant Staphylococcus aureus (MRSA) infections occurred in US dialysis patients in 2010. Frequent hospital visits and prolonged bloodstream access, especially via central venous catheters (CVCs), are risk factors among hemodialysis patients. We describe the epidemiology of and recent trends in invasive MRSA infections among dialysis patients. METHODS: We analyzed population-based data from 9 US metropolitan areas from 2005 to 2011...
November 2013: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/23273080/safety-of-everolimus-by-treatment-duration-in-patients-with-advanced-renal-cell-cancer-in-an-expanded-access-program
#16
Alfonsus J M van den Eertwegh, Pierre Karakiewicz, Sevil Bavbek, Sun Young Rha, Sergio Bracarda, Amit Bahl, Yen-chuan Ou, Dennis Kim, Ashok Panneerselvam, Oezlem Anak, Viktor Grünwald
OBJECTIVE: To retrospectively analyze the effects of treatment duration on outcomes of everolimus treatment of patients in the RAD001 Expanded-Access Clinical Trial in RCC (REACT) program. METHODS: Patients with metastatic renal cell carcinoma refractory to vascular endothelial growth factor receptor-tyrosine kinase inhibitor received everolimus (10 mg once daily), with dosing interruption or modifications allowed for toxicity. All serious and grade 3/4 adverse events and grade 1/2 adverse events leading to a change in drug administration were reported...
January 2013: Urology
https://www.readbyqxmd.com/read/22989823/clinical-characteristics-of-nursing-and-healthcare-associated-pneumonia-a-japanese-variant-of-healthcare-associated-pneumonia
#17
COMPARATIVE STUDY
Tadashi Ishida, Hiromasa Tachibana, Akihiro Ito, Hiroshige Yoshioka, Machiko Arita, Toru Hashimoto
OBJECTIVE: The aim of this study was to describe the epidemiology, clinical features, antimicrobial treatment, and outcomes of patients with nursing and healthcare-associated pneumonia (NHCAP); a new category of pneumonia proposed by the Japanese Respiratory Society. METHODS: We conducted a retrospective analysis of a prospectively collected database of patients with NHCAP and community-acquired pneumonia (CAP) hospitalized at a single center between January 2008 and December 2010, and compared their clinical characteristics...
2012: Internal Medicine
https://www.readbyqxmd.com/read/22904124/association-of-dialysis-modality-with-risk-for-infection-related-hospitalization-a-propensity-score-matched-cohort-analysis
#18
COMPARATIVE STUDY
Jean-Philippe Lafrance, Elham Rahme, Sameena Iqbal, Naoual Elftouh, Michel Vallée, Louis-Philippe Laurin, Denis Ouimet
BACKGROUND AND OBJECTIVES: Peritonitis is a well known complication of peritoneal dialysis (PD), whereas in hemodialysis (HD), bacteremia can be life threatening. Whether patients undergoing PD have higher risk than HD patients for infection-related hospitalizations (IRH) remains unknown. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: A propensity score-matched retrospective cohort of patients undergoing long-term dialysis between January 2001 and December 2007 was assembled...
October 2012: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/22892085/-septic-pulmonary-embolism-of-cutaneous-origin
#19
Agustina Sosa Beláustegui, Santiago Flagel, Eveling A Soraide, Glenda Guzmán, Beatriz Perazzi, Angela Famiglietti
Septic pulmonary embolism is a serious and rare illness characterized by pulmonary infiltrates associated with an extrapulmonary infectious focus. It is mainly related to right-sided endocarditis, pelvic thrombophlebitis, vascular access and less frequently to deep infections such as osteomyelitis, septic arthritis and pyomyositis. The community-acquired methicillin-resistant Staphylococcus aureus (MRSA) is an emerging pathogen with high virulence and rapid spread involving subjects without previous related diseases or known risk factors...
2012: Medicina
https://www.readbyqxmd.com/read/22532173/is-pre-existing-dementia-an-independent-predictor-of-outcome-after-stroke-a-propensity-score-matched-analysis
#20
Gustavo Saposnik, Moira K Kapral, Robert Cote, Paula A Rochon, Julie Wang, Stavroula Raptis, Muhammad Mamdani, Sandra E Black
With an aging population, patients are increasingly likely to present with stroke and pre-existing dementia, which may lead to greater death and disability. The aim of this work was to assess the risk of all-cause mortality and poor functional outcomes after ischemic stroke in patients with and without pre-existing dementia. We conducted a multicenter cohort study of all patients presenting to 12 tertiary care institutions participating in the Registry of the Canadian Stroke Network (RCSN) with a first ischemic stroke between 2003 and 2008...
November 2012: Journal of Neurology
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