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https://www.readbyqxmd.com/read/28329336/remote-ischaemic-preconditioning-reduces-acute-kidney-injury-in-adult-patients-undergoing-cardiac-surgery-with-cardiopulmonary-bypass-a-meta-analysis
#1
Bin Yi, Xiang Chen, Han Shi, Tiao Lin, Haifeng Lin, Yi Xu, Jian Rong
This article represents the first attempt to perform a pooled analysis about remote ischaemic preconditioning (RIPC) in reduction of acute kidney injury (AKI) of adult patients undergoing cardiac surgery with cardiopulmonary bypass (CPB). A systematic search was performed using PubMed (1966-5 January 2016), the Cochrane Library (1996-5 January 2016), the Web of Science (1986-5 January 2016) and Chinese database (SinoMed) (1978-5 January 2016) to identify studies that have described the effect of RIPC on AKI in adult patients undergoing cardiac surgery with CPB...
December 22, 2016: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/28329088/short-course-adjunctive-gentamicin-as-empirical-therapy-in-patients-with-severe-sepsis-and-septic-shock-a-prospective-observational-cohort-study
#2
David S Y Ong, Jos F Frencken, Peter M C Klein Klouwenberg, Nicole Juffermans, Tom van der Poll, Marc Bonten, Olaf Cremer
Background.: Meta-analyses failed to demonstrate clinical benefits of beta lactam plus aminoglycoside combination therapy, compared to beta lactam monotherapy, in patients with sepsis. However, few data exist on the effects of short-course adjunctive aminoglycoside therapy in sepsis patients with organ failure or shock. Methods.: We prospectively enrolled consecutive patients with severe sepsis or septic shock in two intensive care units in the Netherlands from 2011 to 2015...
February 28, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28329026/the-effect-of-early-versus-late-initiation-of-renal-replacement-therapy-in-patients-with-acute-kidney-injury-a-meta-analysis-with-trial-sequential-analysis-of-randomized-controlled-trials
#3
Yan-Mei Feng, Yuan Yang, Xiao-Li Han, Fan Zhang, Dong Wan, Rui Guo
BACKGROUND: The optimal timing for initiating renal replacement therapy (RRT) in patients with acute kidney injury (AKI) remains controversial. METHODS: We conducted a meta-analysis with trial sequential analysis (TSA) of randomized controlled trials (RCTs) using PUBMED, Cochrane Library databases, and Web of Science (from January 1, 1985, to August 21, 2016). Adult patients with AKI who received RRT with different timing were included. The primary outcome was mortality...
2017: PloS One
https://www.readbyqxmd.com/read/28322584/editorial-comment-on-end-2016-0851-ra-r1
#4
Sara L Best
In their meta-analysis, Jones and colleagues found that bilateral synchronous PCNL was associated with similar stone free outcomes and complication rates as those reported for unilateral PCNL. The authors do an excellent job in emphasizing that BS-PCNL has primarily been reported by high volume centers. Previous investigations have demonstrated that PCNL outcomes are better and complication rates are lower at high volume centers.(1) Institutions that perform few PCNLs should be cautious about performing simultaneous bilateral procedures as their complication rate may be higher and exposing the patient to acute kidney injury could prove devastating...
March 21, 2017: Journal of Endourology
https://www.readbyqxmd.com/read/28306589/older-adult-kidney-function-assessment-and-rounding-creatinine-led-to-medication-dosing-error
#5
Timothy Nguyen, Yanique Foster, Shpres Cekaj
BACKGROUND/AREAS OF UNCERTAINTY: Kidney function assessment in older adults can be unreliable because of many factors, and inaccurate assessment can lead to medication dosing error. Practitioners may have adopted the method of rounding creatinine to an arbitrary number 1.0 because of change in muscle mass and age-related change. This has in fact proven to cause more harm than good, potentially leading to underdosing of many medications. DATA SOURCES: A literature search performed using PubMed with the following key words (rounding serum creatinine, rounding serum creatinine AND pharmacist or pharmacy, rounding serum creatinine AND doctor or physician or healthcare, rounding serum creatinine AND kidney function) with no restrictions (dates or any other requirement)...
March 1, 2017: American Journal of Therapeutics
https://www.readbyqxmd.com/read/28303428/outcomes-of-laparoscopic-and-robotic-partial-nephrectomy-for-large-4%C3%A2-cm-kidney-tumors-systematic-review-and-meta-analysis
#6
REVIEW
Nicola Pavan, Ithaar H Derweesh, Carme Maria Mir, Giacomo Novara, Lance J Hampton, Matteo Ferro, Sisto Perdonà, Dipen J Parekh, Francesco Porpiglia, Riccardo Autorino
PURPOSE: The aim of this study was to assess the outcomes of minimally invasive (laparoscopic and robotic) partial nephrectomy (MIPN) for large renal masses. MATERIALS AND METHODS: A systematic literature review was performed up to September 2016 using multiple search engines to identify studies comparing MIPN for tumors larger than 4 cm (>cT1a) with MIPN for tumors smaller than 4 cm (cT1a). The preferred reporting items for systematic reviews and meta-analyses (PRISMA) criteria were used for article selection...
March 16, 2017: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/28303021/age-and-surgical-complexity-impact-on-renoprotection-by-remote-ischemic-preconditioning-during-adult-cardiac-surgery-a-meta-analysis
#7
Chenghui Zhou, Heerajnarain Bulluck, Nengxin Fang, Lihuan Li, Derek J Hausenloy
We aimed to conduct an up-to-date meta-analysis to comprehensively assess the renoprotective effect of remote ischemic preconditioning (RIPC) in patients undergoing adult cardiac surgery. 21 randomized controlled trials (RCTs) with a total of 6302 patients were selected and identified. Compared with controls, RIPC significantly reduced the incidence of acute kidney injury (AKI) [odds ratio (OR) = 0.79; P = 0.02; I(2) = 38%], and in particular, AKI stage I (OR = 0.65; P = 0.01; I(2) = 55%)...
March 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28295643/prophylaxis-of-lymphocele-formation-after-kidney-transplantation-via-peritoneal-fenestration-a-systematic-review
#8
André Leopold Mihaljevic, Patrick Heger, Sepehr Abbasi Dezfouli, Mohammad Golriz, Arianeb Mehrabi
BACKGROUND: Lymphocele formation after kidney transplantation is a frequent complication which causes pain, secondary graft loss, rehospitalisations and reoperations. Therefore prophylaxis of lymphocele formation is of utmost importance. OBJECTIVE: To assess the effectiveness of peritoneal fenestration in renal transplantation to prevent lymphocele development METHODS: A systematic literature search was conducted combined with hand-searches on lymphocele prevention following renal transplantation using peritoneal fenestration...
March 14, 2017: Transplant International: Official Journal of the European Society for Organ Transplantation
https://www.readbyqxmd.com/read/28291624/corrigendum-to-contrast-media-use-in-patients-with-chronic-kidney-disease-undergoing-coronary-angiography-a-systematic-review-and-meta-analysis-of-randomized-trials-int-j-cardiol-2017-137-144
#9
Bhavi Pandya, Jean M Chalhoub, Valay Parikh, Sainath Gaddam, Jonathan Spagnola, Suzanne El-Sayegh, Marc Bogin, Ruben Kandov, James Lafferty, Sripal Bangalore
No abstract text is available yet for this article.
March 11, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28290837/-the-choice-of-anticoagulant-therapy-in-patients-with-non-valvular-atrial-fibrillation-and-chronic-kidney-disease
#10
N A Koziolova, E A Polyanskaya, I I Kolegova
The review shows the prevalence of atrial fibrillation (AF) in patients with chronic kidney disease (CKD), depending on the severity of the disease. Patients with non-valvular AF and CKD have a significantly increased risk of both bleeding and thromboembolic complications, and death from all causes. Evaluation of the results of randomized clinical trials (RCTs), meta-analyzes of RCTs demonstrated the advantages of the new oral anticoagulants (NOAC), such as dabigatran, rivaroxaban, apixaban, compared with warfarin in reducing the risk of bleeding in patients with AF and CKD in predialysis stage...
January 2017: Kardiologiia
https://www.readbyqxmd.com/read/28288249/association-of-intensive-blood-pressure-control-and-kidney-disease-progression-in-nondiabetic-patients-with-chronic-kidney-disease-a-systematic-review-and-meta-analysis
#11
Wan-Chuan Tsai, Hon-Yen Wu, Yu-Sen Peng, Ju-Yeh Yang, Hung-Yuan Chen, Yen-Ling Chiu, Shih-Ping Hsu, Mei-Ju Ko, Mei-Fen Pai, Yu-Kang Tu, Kuan-Yu Hung, Kuo-Liong Chien
Importance: The optimal blood pressure (BP) target remains debated in nondiabetic patients with chronic kidney disease (CKD). Objective: To compare intensive BP control (<130/80 mm Hg) with standard BP control (<140/90 mm Hg) on major renal outcomes in patients with CKD without diabetes. Data Sources: Searches of PubMed, MEDLINE, Embase, and Cochrane Library for publications up to March 24, 2016. Study Selection: Randomized clinical trials that compared an intensive vs a standard BP target in nondiabetic adults with CKD, reporting changes in glomerular filtration rate (GFR), doubling of serum creatinine level, 50% reduction in GFR, end-stage renal disease (ESRD), or all-cause mortality...
March 13, 2017: JAMA Internal Medicine
https://www.readbyqxmd.com/read/28288025/coffee-and-cancer-risk-a-summary-overview
#12
Gianfranco Alicandro, Alessandra Tavani, Carlo La Vecchia
We reviewed available evidence on coffee drinking and the risk of all cancers and selected cancers updated to May 2016. Coffee consumption is not associated with overall cancer risk. A meta-analysis reported a pooled relative risk (RR) for an increment of 1 cup of coffee/day of 1.00 [95% confidence interval (CI): 0.99-1.01] for all cancers. Coffee drinking is associated with a reduced risk of liver cancer. A meta-analysis of cohort studies found an RR for an increment of consumption of 1 cup/day of 0.85 (95% CI: 0...
March 10, 2017: European Journal of Cancer Prevention
https://www.readbyqxmd.com/read/28284738/procedure-specific-risks-of-thrombosis-and-bleeding-in-urological-non-cancer-surgery-systematic-review-and-meta-analysis
#13
REVIEW
Kari A O Tikkinen, Samantha Craigie, Arnav Agarwal, Reed A C Siemieniuk, Rufus Cartwright, Philippe D Violette, Giacomo Novara, Richard Naspro, Chika Agbassi, Bassel Ali, Maha Imam, Nofisat Ismaila, Denise Kam, Michael K Gould, Per Morten Sandset, Gordon H Guyatt
CONTEXT: Pharmacological thromboprophylaxis involves a trade-off between a reduction in venous thromboembolism (VTE) and increased bleeding. No guidance specific for procedure and patient factors exists in urology. OBJECTIVE: To inform estimates of absolute risk of symptomatic VTE and bleeding requiring reoperation in urological non-cancer surgery. EVIDENCE ACQUISITION: We searched for contemporary observational studies and estimated the risk of symptomatic VTE or bleeding requiring reoperation in the 4 wk after urological surgery...
March 8, 2017: European Urology
https://www.readbyqxmd.com/read/28280699/contrast-induced-acute-kidney-injury-in-kidney-transplant-recipients-a-systematic-review-and-meta-analysis
#14
Wisit Cheungpasitporn, Charat Thongprayoon, Michael A Mao, Shennen A Mao, Matthew R D'Costa, Wonngarm Kittanamongkolchai, Kianoush B Kashani
AIM: To evaluate the incidence of contrast-induced acute kidney injury (CIAKI) in kidney transplant recipients. METHODS: A literature search was performed using MEDLINE, EMBASE, and the Cochrane Database of Systematic Reviews from the inception of the databases through July 2016. Studies assessing the incidence of CIAKI in kidney transplant recipients were included. We applied a random-effects model to estimate the incidence of CIAKI. RESULTS: Six studies of 431 kidney transplant recipients were included in the analyses to assess the incidence of CIAKI in kidney transplant recipients...
February 24, 2017: World Journal of Transplantation
https://www.readbyqxmd.com/read/28277013/examining-the-efficacy-of-social-psychological-interventions-for-the-management-of-fatigue-in-end-stage-kidney-disease-eskd-a-systematic-review-with-meta-analysis
#15
Federica Picariello, Joanna L Hudson, Rona Moss-Morris, Iain C Macdougall, Joseph Chilcot
Fatigue affects between 42% and 89% of end-stage kidney disease (ESKD) patients, with significant repercussions on quality of life and clinical outcomes. Fatigue management revolves around pharmacotherapy or exercise, which have only modest and short-term improvements. The aim of this systematic review was to investigate whether social-psychological interventions are effective at reducing fatigue in ESKD. Databases were searched to identify randomized controlled trials (RCTs) and quasi-RCTs that determined the effect of social-psychological interventions on fatigue (primary or secondary outcome), in the renal patient population...
March 6, 2017: Health Psychology Review
https://www.readbyqxmd.com/read/28271326/the-impact-of-metformin-use-on-survival-in-kidney-cancer-patients-with-diabetes-a-meta-analysis
#16
Yang Li, Liyi Hu, Qinghong Xia, Yongqiang Yuan, Yonghua Mi
PURPOSE: The effects of metformin on the prognosis of kidney cancer patients with diabetes are in controversial. The present study is conducted to classify the association of metformin use with the survival of patients with kidney cancer. METHODS: Electronic databases, namely PubMed and Web of Science, were used to search the eligible studies up to December, 2016. Pooled hazard ratio (HR) and its corresponding 95% confidence interval (95% CI) were calculated. It was considered as statistically significant when P value was <0...
March 7, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28270640/prevalence-of-depression-in-hemodialysis-patients-in-iran-a-systematic-review-and-meta-analysis
#17
Hamid Ravaghi, Masoud Behzadifar, Meysam Behzadifar, Masood Taheri Mirghaed, Aidin Aryankhesal, Morteza Salemi, Nicola Luigi Bragazzi
INTRODUCTION: Chronic kidney disease is a public health problem worldwide that is highly associated with psychological disorders. This study aimed to assess prevalence of depression in hemodialysis patients in Iran. MATERIALS AND METHODS: Relevant studies were identified from the PubMed, ISI Web of Science, Ovid, Scopus, EMBase, and Iranian databases including Magiran, SID, IranMedex, and Irandoc, up to December 2015. The DerSimonian-Laird random effects model was employed to estimate the overall pooled prevalence...
March 2017: Iranian Journal of Kidney Diseases
https://www.readbyqxmd.com/read/28266136/the-effects-of-dipeptidyl-peptidase-4-inhibitors-in-type-2-diabetic-patients-with-moderate-to-severe-chronic-kidney-disease-meta-analysis-of-randomized-controlled-trials-by-using-unadjusted-data
#18
Man Yang, Ling Wang, Lijie Gu, Weijie Yuan
BACKGROUND: Three meta-analyses evaluated the effects of dipeptidyl peptidase-4 (DPP-4) inhibitors in type 2 diabetic patients with chronic kidney disease (CKD) recently. However, direct combination of adjusted and unadjusted data in these meta-analyses, which may be questionable. The present study aimed to perform a meta-analysis of the effects of DPP-4 inhibitors in type 2 diabetic patients with moderate to severe CKD, by using unadjusted data from randomized controlled trials (RCTs)...
March 7, 2017: Journal of Diabetes
https://www.readbyqxmd.com/read/28265827/association-of-helicobacter-pylori-with-chronic-kidney-diseases-a-meta-analysis
#19
Karn Wijarnpreecha, Charat Thongprayoon, Pitchaphon Nissaisorakarn, Veeravich Jaruvongvanich, Kiran Nakkala, Ridhmi Rajapakse, Wisit Cheungpasitporn
BACKGROUND/OBJECTIVES: The reported risk of chronic kidney disease (CKD) in patients with Helicobacter pylori infection is conflicting. This meta-analysis was conducted to summarize all available data and to estimate the prevalence and association between H. pylori and kidney disease and CKD. METHODS: Comprehensive literature review was conducted using MEDLINE and EMBASE database through October 2016 to identify studies that reported the prevalence or the association between H...
March 6, 2017: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/28262412/minimally-invasive-laparoscopic-and-robotic-assisted-techniques-versus-open-techniques-for-kidney-transplant-recipients-a-systematic-review
#20
Sven Wagenaar, Johanna H Nederhoed, Arjan W J Hoksbergen, H Jaap Bonjer, Willem Wisselink, Gabrielle H van Ramshorst
CONTEXT: Literature on conventional and minimally invasive operative techniques has not been systematically reviewed for kidney transplant recipients. OBJECTIVE: To systematically evaluate, summarize, and review evidence supporting operating technique and postoperative outcome for kidney transplant recipients. EVIDENCE ACQUISITION: A systematic review was conducted in PubMed-Medline, Embase, and Cochrane Library between 1966 up to September 1, 2016, according to Preferred Reporting Items for Systematic Review and Meta-analysis guidelines...
March 3, 2017: European Urology
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