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Vascular Calification

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https://www.readbyqxmd.com/read/28693029/angio-oct-de-la-zona-avascular-foveal-en-ojos-con-oclusi%C3%A3-n-venosa-de-la-retina
#1
Juliana Wons, Maximilian Pfau, Magdalena A Wirth, Florentina J Freiberg, Matthias D Becker, Stephan Michels
Objetivo: El objetivo del estudio comprendía visualizar y cuantificar las alteraciones patológicas de la zona avascular foveal (ZAF) mediante angio-OCT en ojos con oclusión venosa de la retina (OVR) en comparación con el ojo contralateral sano. Procedimientos: La angio-OCT se llevó a cabo mediante el sistema Avanti® RTVue 100 XR (Optovue Inc., Fremont, Calif., EE. UU.). Los bordes de la capa vascular superficial (CVS) se definieron como 3 μm por debajo de la membrana limitante interna y 15 μm por debajo de la capa plexiforme interna y, para la capa vascular profunda (CVP), como 15 y 70 μm por debajo de la membrana limitante interna y de la capa plexiforme interna, respectivamente...
July 11, 2017: Ophthalmologica. Journal International D'ophtalmologie
https://www.readbyqxmd.com/read/28666823/overstenting-the-hypogastric-artery-during-endovascular-aneurysm-repair-with-and-without-prior-coil-embolization-a%C3%A2-comparative-analysis-from-the-engage-registry
#2
Rutger A Stokmans, Pieter P H L Broos, Marc R H M van Sambeek, Joep A W Teijink, Philippe W M Cuypers
BACKGROUND: Endovascular aneurysm repair of aortoiliac or iliac aneurysms is often performed with stent graft coverage of the origin of the hypogastric artery (HA) to ensure adequate distal seal. It is considered common practice to perform adjunctive coiling of the HA to prevent a type II endoleak. Our objective was to question the necessity of pre-emptive coiling by comparing the outcomes of HA coverage with and without prior coil embolization. METHODS: Data from the Endurant Stent Graft Natural Selection Global Postmarket Registry (ENGAGE), which prospectively enrolled 1263 endovascular aneurysm repair patients between March 2009 and April 2011 from multiple centers worldwide, were used for this study...
June 27, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28655551/adult-venous-endothelium-is-a-niche-for-highly-proliferative-and-vasculogenic-endothelial-colony-forming-cells
#3
Linden Green, Richard H Ofstein, Brian Rapp, M Reza Saadatzadeh, Janak R Bhavsar, Andres Fajardo, Michael C Dalsing, David A Ingram, Michael P Murphy
OBJECTIVE: Postnatal resident endothelium of blood vessels has been proposed to represent terminally differentiated tissue that does not replicate. We previously isolated endothelial colony-forming cells (ECFCs) from human umbilical cord blood (CB) and term placenta by using colony-forming assays and immunocytochemistry. We showed that ECFCs are highly proliferative and form functioning vessels in vivo, the defining characteristics of a true endothelial progenitor cell. This exploratory investigation was conducted to determine whether the endothelium of healthy adult blood vessels contained resident ECFCs...
June 24, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28583728/conical-neck-is-strongly-associated-with-proximal-failure-in-standard-endovascular-aneurysm-repair
#4
Georgios A Pitoulias, Andrés Reyes Valdivia, Suteekhanit Hahtapornsawan, Giovanni Torsello, Apostolos G Pitoulias, Martin Austermann, Claudio Gandarias, Konstantinos P Donas
OBJECTIVE: Hostile proximal aortic neck (HN) challenges the suitability for standard endovascular aneurysm repair (EVAR) of patients at high risk for "open" repair. However, there has been little if any focus placed on the individual role of the "nonlength" HN features in EVAR outcomes. The aim of this study was to evaluate their individual and potentially predictive role in outcomes of EVAR under HN conditions. METHODS: Data of 156 consecutive EVAR patients with short (<15 mm) HN, treated with the Endurant device (Medtronic Cardiovascular, Santa Rosa, Calif) at three European academic vascular centers between 2007 and 2015, were collected and retrospectively analyzed...
June 2, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28571880/%C3%AE-tocopherol-especially-%C3%AE-tocopherol-phosphate-exerts-antiapoptotic-and-angiogenic-effects-on-rat-bone-marrow-derived-endothelial-progenitor-cells-under-high-glucose-and-hypoxia-conditions
#5
Ziheng Wu, Xiangtao Zheng, Luyang Meng, Xin Fang, Yangyan He, Donglin Li, Chengfei Zheng, Hongkun Zhang
OBJECTIVE: Considering the poor efficacy of local intramuscular injections with endothelial progenitor cells (EPCs) for critical limb ischemia in patients with diabetes, the study aimed to investigate the effect of α-tocopherol (α-T) and α-tocopherol phosphate (α-TP) on apoptosis and angiogenesis in a rat model under oxidative stress conditions. METHODS: Primary EPCs from Sprague-Dawley rats were harvested and treated with α-T and α-TP for 24 hours. Gene transcription and protein expression were evaluated by real-time polymerase chain reaction and Western blot, respectively...
May 29, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28385296/17%C3%AE-estradiol-prevents-mesenteric-injury-induced-by-occlusion-of-the-proximal-descending-aorta-in-male-rats
#6
Paulo Thales Rocha de Sousa, Ana Cristina Breithaupt-Faloppa, Cristiano de Jesus Correia, Raif Restivo Simão, Sueli Gomes Ferreira, Alfredo Inácio Fiorelli, Luiz Felipe Pinho Moreira, Paulina Sannomiya
OBJECTIVE: In surgical aortic repair or cardiac surgery with aorta occlusion, the occurrence of mesenteric ischemia and bowel injury has been associated with higher short-term mortality. The vascular protection of estrogens has been investigated and is mainly mediated by increasing the availability of nitric oxide (NO). Therefore, this study investigated the role of 17β-estradiol on visceral ischemia-reperfusion (I/R) injury after descending aorta occlusion in male rats. METHODS: Mesenteric ischemia was induced in male Wistar rats by placing a 2F Fogarty arterial embolectomy catheter (Edwards Lifesciences, Irvine, Calif) in the descending aorta, which remained occluded for 15 minutes, followed by reperfusion for up to 2 hours...
April 3, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28366302/results-of-the-valor-ii-trial-of-the-medtronic-valiant-thoracic-stent-graft
#7
Mark F Conrad, James Tuchek, Robert Freezor, Joseph Bavaria, Rodney White, Ronald Fairman
BACKGROUND: The 1-year results of endovascular exclusion of degenerative descending thoracic aortic aneurysms (DTA) with the Valiant Thoracic Stent Graft (Medtronic Vascular, Santa Rosa, Calif) have been previously reported. With long-term follow-up now complete, the 5-year results are reported. METHODS: The VALOR II trial (Evaluation of the Clinical Performance of the Valiant Thoracic Stent Graft System in the Treatment of Descending Thoracic Aneurysms of Degenerative Etiology in Subjects Who Are Candidates for Endovascular Repair) was a prospective, nonrandomized trial of the Valiant Thoracic Stent Graft system in patients with degenerative DTA...
March 30, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28214484/hybrid-operative-thrombectomy-is-noninferior-to-percutaneous-techniques-for-the-treatment-of-acute-iliofemoral-deep-venous-thrombosis
#8
Limael E Rodríguez, Aihab Aboukheir-Aboukheir, Ricardo Figueroa-Vicente, Hiram Soler-Bernardini, Guillermo Bolanos-Avila, Luis J Torruella-Bartolomei, Anthony J Comerota, Jorge L Martinez-Trabal
OBJECTIVE: Hybrid operative thrombectomy (HOT) is a novel technique for the treatment of acute iliofemoral deep venous thrombosis (IFDVT) and is an alternative to percutaneous techniques (PTs) that use thrombolytics. In this study, we compare perioperative and intermediate outcomes of HOT vs PT as interventions for early thrombus removal. METHODS: From July 2008 to May 2015, there were 71 consecutive patients who were treated with either PT (n = 31) or HOT (n = 40) for acute or subacute single-limb IFDVT...
March 2017: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://www.readbyqxmd.com/read/28190719/feasibility-and-pilot-efficacy-of-a-brief-smoking-cessation-intervention-delivered-by-vascular-surgeons-in-the-vascular-physician-offer-and-report-vapor-trial
#9
RANDOMIZED CONTROLLED TRIAL
Philip P Goodney, Emily L Spangler, Karina Newhall, Benjamin S Brooke, Andres Schanzer, Tze-Woei Tan, Adam W Beck, John H Hallett, Todd A MacKenzie, Maria O Edelen, Andrew W Hoel, Nancy A Rigotti, Alik Farber
BACKGROUND: This study determined the feasibility and potential efficacy of an evidence-based standardized smoking cessation intervention delivered by vascular surgeons to smokers with peripheral arterial disease. METHODS: We performed a cluster-randomized trial of current adult smokers referred to eight vascular surgery practices from September 1, 2014, to July 31, 2015. A three-component smoking cessation intervention (physician advice, nicotine replacement therapy, and telephone-based quitline referral) was compared with usual care...
April 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/27986486/one-year-pivotal-trial-outcomes-of-the-nellix-system-for-endovascular-aneurysm-sealing
#10
MULTICENTER STUDY
Jeffrey P Carpenter, Robert Cuff, Clifford Buckley, Christopher Healey, Sajjad Hussain, Michel M P J Reijnen, Jose Trani, Dittmar Böckler
OBJECTIVE: The Nellix EndoVascular Aneurysm Sealing (EVAS) System (Endologix, Inc, Irvine, Calif) is a novel approach to abdominal aortic aneurysm (AAA) treatment whereby polymer is used to fill the AAA sac. We report 1-year results of the investigational device exemption pivotal trial. METHODS: Eligible patients were treated at 30 sites in the United States and Europe. Inclusion criteria required an asymptomatic infrarenal AAA, with a neck length ≥10 mm and ≤60° angle, iliac artery blood lumen diameter 9 to 35 mm, access artery diameter ≥6 mm, and serum creatinine ≤2 mg/dL...
February 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/27876520/explaining-endograft-shortening-during-endovascular-repair-of-abdominal-aortic-aneurysms-in-severe-aortoiliac-tortuosity
#11
Kevin Lee, Sajjid Hossain, Maher Sabalbal, Luc Dubois, Audra Duncan, Guy DeRose, Adam H Power
OBJECTIVE: During endovascular aneurysm repair (EVAR), severely tortuous aortoiliac anatomy can alter the deployment and conformability of the endograft. The accuracy of treatment length measurements is commonly recognized to be affected by severe tortuosity. However, the exact mechanism of the postintervention length discrepancy is poorly understood. The objective of this study was to determine the mechanism of how severe aortoiliac tortuosity influences the endograft and native aorta during EVAR and its impact on the distal sealing zone...
May 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/27776696/preservation-of-hypogastric-flow-and-control-of-iliac-aneurysm-size-in-the-treatment-of-aortoiliac-aneurysms-using-the-nellix-endovascular-aneurysm-sealing-endograft
#12
MULTICENTER STUDY
Dainis K Krievins, Janis Savlovskis, Andrew H Holden, Kaspars Kisis, Andrew A Hill, Marcis Gedins, Natalija Ezite, Christopher K Zarins
OBJECTIVE: The purpose of this study was to determine the long-term effectiveness of endovascular aneurysm sealing (EVAS) in the treatment of complex aortoiliac aneurysms with preservation of hypogastric artery flow. METHODS: We reviewed all patients with abdominal aortic aneurysms (AAAs) and common iliac aneurysms (CIAs) enrolled and treated in prospective studies of EVAS using the Nellix endograft (Endologix, Irvine, Calif) at two centers from 2008 to 2014. Patients with 1 year or more of computed tomography follow-up underwent quantitative morphometric assessment by two independent vascular radiologists blinded to clinical outcome results...
November 2016: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/27606681/findings-of-optical-coherence-tomographic-angiography-at-the-choriocapillaris-level-in-central-serous-chorioretinopathy
#13
Ari Shinojima, Akiyuki Kawamura, Ryusaburo Mori, Kyoko Fujita, Mitsuko Yuzawa
PURPOSE: To reveal vascular signals at the choriocapillaris level in central serous chorioretinopathy (CSC) using optical coherence tomographic angiography (OCTA). PROCEDURES: We analyzed vascular signals at the choriocapillaris level in 58 CSC and 51 contralateral eyes by OCTA (RTVue XR Avanti with AngioVue; Optovue Inc., Fremont, Calif., USA). Data analysis included age, best corrected visual acuity (BCVA), disease duration and serous retinal detachment (SRD) height...
2016: Ophthalmologica. Journal International D'ophtalmologie
https://www.readbyqxmd.com/read/27514438/fibroblast-growth-factor-and-vascular-endothelial-growth-factor-play-a-critical-role-in-endotheliogenesis-from-human-adipose-derived-stem-cells
#14
Sophia Khan, Miguel A Villalobos, Rachel L Choron, Shaohua Chang, Spencer A Brown, Jeffrey P Carpenter, Thomas N Tulenko, Ping Zhang
OBJECTIVE: Adipose-derived stem cells (ASCs) are a potential adult mesenchymal stem cell source for restoring endothelial function in patients with critical limb ischemia. Fibroblast growth factor 2 (FGF2) and vascular endothelial growth factor (VEGF) play a major role in angiogenesis and wound healing. This study evaluated the effects of FGF and VEGF on the proliferation, migration, and potential endothelial differentiation of human ASCs with regards to their use as endothelial cell substitutes...
May 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/27444365/analysis-of-endovascular-therapy-for-femoropopliteal-disease-with-the-supera-stent
#15
Miguel Montero-Baker, Gregory J Ziomek, Luis Leon, Aaron Gonzales, Robert S Dieter, Crystal L Gadd, John P Pacanowski
BACKGROUND: The structural limitations of currently available laser-cut nitinol stents in the highly diseased arterial system of the lower extremity are well described. These devices are frequently used in long-segment occlusions, at the adductor hiatus, and across the knee into the popliteal artery and tibial-peroneal trunk despite concerns related to the high mobility of the knee joint and the potential for external stent compression, fractures, and occlusion. The Supera stent (Abbott Vascular, Santa Clara, Calif) was developed to provide superior radial strength, fracture resistance, and flexibility compared with laser-cut nitinol stents...
October 2016: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/27237404/safety-and-effectiveness-of-total-percutaneous-access-for-fenestrated-endovascular-aortic-aneurysm-repair
#16
David E Timaran, Marilisa Soto, Martyn Knowles, J Gregory Modrall, John E Rectenwald, Carlos H Timaran
BACKGROUND: Percutaneous femoral vascular access is frequently used for aortic endovascular procedures, with a local access complication rate of 5% to 16%. Fenestrated endovascular aneurysm repair (FEVAR) has recently emerged as a new technique for the repair of short-neck and juxtarenal abdominal aortic aneurysms. The safety and effectiveness of percutaneous access for FEVAR has not been established to date. METHODS: Since United States Food and Drug Administration approval of the Zenith fenestrated aortic endograft (Cook Medical, Bloomington, Ind), 94 patients (60 Zenith fenestrated, 6 p-Branch, and 28 custom-made devices) have undergone FEVAR...
October 2016: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/27160007/optical-coherence-tomography-angiography-of-the-foveal-avascular-zone-in-retinal-vein-occlusion
#17
Juliana Wons, Maximilian Pfau, Magdalena A Wirth, Florentina J Freiberg, Matthias D Becker, Stephan Michels
PURPOSE: The aim of the study was to visualize and to quantify pathological foveal avascular zone (FAZ) alterations through optical coherence tomography angiography (OCT-A) in eyes with retinal vein occlusion (RVO) in comparison to the unaffected fellow eyes. PROCEDURES: OCT-A was conducted with the Avanti® RTVue 100 XR system (Optovue Inc., Fremont, Calif., USA). The borders of the superficial vascular layer (SVL) were defined as 3 μm below the internal limiting membrane and 15 μm below the inner plexiform layer, and for the deep vascular layer (DVL) as 15 and 70 μm below the inner plexiform layer, respectively...
2016: Ophthalmologica. Journal International D'ophtalmologie
https://www.readbyqxmd.com/read/26994956/late-single-center-outcome-of-the-talent-abdominal-stent-graft-after-a-decade-of-follow-up
#18
Yannick W 't Mannetje, Pieter P H L Broos, Roy F A van Poppel, Marc R H M van Sambeek, Joep A W Teijink, Philippe W M Cuypers
OBJECTIVE: Lifelong yearly surveillance is advised after endovascular aneurysm repair (EVAR) for abdominal aortic aneurysms. This follow-up requires a substantial amount of health care resources. The aim of this paper was to assess the occurrence of stent graft-related complications and secondary interventions during a minimum 10-year follow-up after elective EVAR. METHODS: Patients who were treated in a high-volume endovascular center in The Netherlands with the Talent infrarenal stent graft (Medtronic Vascular, Santa Rosa, Calif) between June 1999 and February 2005 were included...
September 2016: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/26937802/prediction-of-low-versus-high-recurrence-scores-in-estrogen-receptor-positive-lymph-node-negative-invasive-breast-cancer-on-the-basis-of-radiologic-pathologic-features-comparison-with-oncotype-dx-test-recurrence-scores
#19
COMPARATIVE STUDY
Vandana Dialani, Shantanu Gaur, Tejas S Mehta, Shambhavi Venkataraman, Valerie Fein-Zachary, Jordana Phillips, Alexander Brook, Priscilla J Slanetz
Purpose To review mammographic, ultrasonographic (US), and magnetic resonance (MR) imaging features and pathologic characteristics of estrogen receptor (ER)-positive, lymph node-negative invasive breast cancer and to determine the relationship of these characteristics to Oncotype DX (Genomic Health, Redwood City, Calif) test recurrence scores (ODRS) for breast cancer recurrence. Materials and Methods This institutional review board-approved retrospective study was performed in a single large academic medical center...
August 2016: Radiology
https://www.readbyqxmd.com/read/26545970/what-is-a-good-result-after-transcatheter-mitral-repair-impact-of-2-residual-mitral-regurgitation
#20
COMPARATIVE STUDY
Nicola Buzzatti, Michele De Bonis, Paolo Denti, Fabio Barili, Davide Schiavi, Giovanna Di Giannuario, Giovanni La Canna, Ottavio Alfieri
OBJECTIVE: The study objective was to assess the impact on follow-up outcomes of residual mitral regurgitation 2+ in comparison with ≤ 1+ after MitraClip (Abbott Vascular Inc, Santa Clara, Calif) repair. METHODS: We compared the outcomes of mitral regurgitation 2+ and mitral regurgitation ≤ 1 + groups among a population of 223 consecutive patients with acute residual mitral regurgitation ≤ 2+ who underwent MitraClip implantation at San Raffaele Scientific Institute (Milan, Italy) between October 2008 and December 2014...
January 2016: Journal of Thoracic and Cardiovascular Surgery
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