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agitation and dementia

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https://www.readbyqxmd.com/read/29149790/impressions-of-using-the-cohen-mansfield-agitation-inventory-as-an-outcome-measure-lessons-learnt-for-future-clinical-researchers-innovative-practice
#1
Lindsey Brett, Victoria Traynor, Shahla Meedya, Paul Stapley
The Cohen-Mansfield Agitation Inventory was a tool originally developed for use in research to measure agitation and subsequently used in clinical settings. It was the primary outcome measure for a randomised controlled trial which evaluated the effects and feasibility of a physiotherapist-led physical exercise intervention on agitation and physical performance of individuals living with dementia in nursing homes. The study produced weak results in regards to the Cohen-Mansfield Agitation Inventory due to small sample size and perceived issues with the use of the Cohen-Mansfield Agitation Inventory...
January 1, 2017: Dementia
https://www.readbyqxmd.com/read/29146222/nursing-staff-distress-associated-with-neuropsychiatric-symptoms-in-young-onset-dementia-and-late-onset-dementia
#2
Jeannette C L van Duinen-van den IJssel, Ans J M J Mulders, Martin Smalbrugge, Sandra A Zwijsen, Britt Appelhof, Syste U Zuidema, Marjolein E de Vugt, Frans R J Verhey, Christian Bakker, Raymond T C M Koopmans
OBJECTIVE: The aims of this study were (1) to investigate the relationship between different neuropsychiatric symptoms (NPS) and the level of distress experienced by nurses caring for residents with young-onset dementia (YOD) and (2) to compare these findings with those for nurses caring for residents with late-onset dementia (LOD). DESIGN/SETTING: This is a retrospective study conducted in Dutch long-term care facilities. Data were used from the Behavior and Evolution of Young-ONset Dementia studies (BEYOND) Parts I and II and the WAAL Behavior in Dementia-II (Waalbed-II) study...
November 14, 2017: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/29136228/opioid-prescription-use-in-nursing-home-residents-with-advanced-dementia
#3
Charlotte Griffioen, Bettina S Husebo, Elisabeth Flo, Monique A A Caljouw, Wilco P Achterberg
Background: Although proper pain treatment may require opioids, discussion continues about possible undertreatment or overtreatment in persons with advanced dementia. Objective: To investigate the prevalence of pain, frequency of opioid prescription use, and factors associated with strong opioid prescription use in nursing homes. Design: Cross-sectional study. Setting and Subjects: Eighteen Norwegian nursing homes; 327 persons with advanced dementia and behavioral disturbances participated...
November 9, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/29130813/museums-health-and-wellbeing-research-co-developing-a-new-observational-method-for-people-with-dementia-in-hospital-contexts
#4
Nuala Morse, Helen Chatterjee
AIMS: The aim of this article is to present a new observational tool for assessing the impacts of museum object handling for people with moderate-to-severe dementia in hospital settings, focusing on wellbeing, social interaction, level of engagement and agitation. This article presents a four-step approach to collaboration towards co-developing the tool, which involved a range of academics, museums professionals, and health and social care partners, and describes the process of integrating multiple perspectives towards common research methodologies...
November 1, 2017: Perspectives in Public Health
https://www.readbyqxmd.com/read/29107460/electroconvulsive-therapy-for-agitation-and-aggression-in-dementia-a-systematic-review
#5
Julia F van den Berg, Henk C Kruithof, Rob M Kok, Esmée Verwijk, Harm-Pieter Spaans
OBJECTIVES: Many patients with dementia develop agitation or aggression in the course of their disease. In some severe cases, behavioral, environmental, and pharmacological interventions are not sufficient to alleviate these potentially life-threatening symptoms. It has been suggested that in those cases, electroconvulsive therapy (ECT) could be an option. This review summarizes the scientific literature on ECT for agitation and aggression in dementia. METHODS: We performed a systematic review in accordance with PRISMA guidelines...
September 25, 2017: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/29107312/using-complementary-and-alternative-medicine-to-treat-pain-and-agitation-in-dementia-a-review-of-randomized-controlled-trials-from-long-term-care-with-potential-use-in-critical-care
#6
REVIEW
Alison R Anderson, Jie Deng, Robert S Anthony, Sebastian A Atalla, Todd B Monroe
The risk of pain in adults with dementia worsens with advancing age. Painful comorbidities may be underassessed and inadequately treated. Receiving treatment in critical care settings may indicate greater occurrences of pain and complications. Pain may exacerbate behavioral and psychological symptoms of dementia (BPSD), such as agitation. Complementary and alternative medicine (CAM) therapies may alleviate pain and BPSD, and continuity of therapy may bolster these therapeutic effects. This review did not reveal an apparent benefit of aromatherapy; however, improvements in BPSD have been shown previously...
December 2017: Critical Care Nursing Clinics of North America
https://www.readbyqxmd.com/read/29100197/using-simulated-family-presence-to-decrease-agitation-in-older-hospitalized-delirious-patients-a-randomized-controlled-trial
#7
Christine M Waszynski, Kerry A Milner, Ilene Staff, Sheila L Molony
BACKGROUND: Simulated family presence has been shown to be an effective nonpharmacological intervention to reduce agitation in persons with dementia in nursing homes. Hyperactive or mixed delirium is a common and serious complication experienced by hospitalized patients, a key feature of which is agitation. Effective nonpharmacological interventions to manage delirium are needed. OBJECTIVES: To examine the effect of simulated family presence through pre-recorded video messages on the agitation level of hospitalized, delirious, acutely agitated patients...
October 7, 2017: International Journal of Nursing Studies
https://www.readbyqxmd.com/read/29073741/a-systematic-review-of-the-effectiveness-of-medical-cannabis-for-psychiatric-movement-and-neurodegenerative-disorders
#8
REVIEW
Keane Lim, Yuen Mei See, Jimmy Lee
The discovery of endocannabinoid's role within the central nervous system and its potential therapeutic benefits have brought forth rising interest in the use of cannabis for medical purposes. The present review aimed to synthesize and evaluate the available evidences on the efficacy of cannabis and its derivatives for psychiatric, neurodegenerative and movement disorders. A systematic search of randomized controlled trials of cannabis and its derivatives were conducted via databases (PubMed, Embase and the Cochrane Central Register of Controlled Trials)...
November 30, 2017: Clinical Psychopharmacology and Neuroscience: the Official Scientific Journal of the Korean College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/29067350/neuropsychiatric-signs-and-symptoms-of-alzheimer-s-disease-new%C3%A2-treatment-paradigms
#9
REVIEW
Krista L Lanctôt, Joan Amatniek, Sonia Ancoli-Israel, Steven E Arnold, Clive Ballard, Jiska Cohen-Mansfield, Zahinoor Ismail, Constantine Lyketsos, David S Miller, Erik Musiek, Ricardo S Osorio, Paul B Rosenberg, Andrew Satlin, David Steffens, Pierre Tariot, Lisa J Bain, Maria C Carrillo, James A Hendrix, Heidi Jurgens, Brendon Boot
Neuropsychiatric symptoms (NPSs) are hallmarks of Alzheimer's disease (AD), causing substantial distress for both people with dementia and their caregivers, and contributing to early institutionalization. They are among the earliest signs and symptoms of neurocognitive disorders and incipient cognitive decline, yet are under-recognized and often challenging to treat. With this in mind, the Alzheimer's Association convened a Research Roundtable in May 2016, bringing together experts from academia, industry, and regulatory agencies to discuss the latest understanding of NPSs and review the development of therapeutics and biomarkers of NPSs in AD...
September 2017: Alzheimer's & Dementia: Translational Research & Clinical Interventions
https://www.readbyqxmd.com/read/29067332/ub-311-a-novel-ubith-%C3%A2-amyloid-%C3%AE-peptide-vaccine-for-mild%C3%A2-alzheimer-s%C3%A2-disease
#10
Chang Yi Wang, Pei-Ning Wang, Ming-Jang Chiu, Connie L Finstad, Feng Lin, Shugene Lynn, Yuan-Hung Tai, Xin De Fang, Kesheng Zhao, Chung-Ho Hung, Yiting Tseng, Wen-Jiun Peng, Jason Wang, Chih-Chieh Yu, Be-Sheng Kuo, Paul A Frohna
INTRODUCTION: A novel amyloid β (Aβ) synthetic peptide vaccine (UB-311) has been evaluated in a first-in-human trial with patients of mild-to-moderate Alzheimer's disease. We describe translational research covering vaccine design, preclinical characterization, and phase-I clinical trial with supportive outcome that advances UB-311 into an ongoing phase-II trial. METHODS: UB-311 is constructed with two synthetic Aβ1-14-targeting peptides (B-cell epitope), each linked to different helper T-cell peptide epitopes (UBITh(®)) and formulated in a Th2-biased delivery system...
June 2017: Alzheimer's & Dementia: Translational Research & Clinical Interventions
https://www.readbyqxmd.com/read/29059136/successful-use-of-escitalopram-for-the-treatment-of-visual-hallucinations-in-patients-with-parkinson-disease
#11
Joseph Bergman, Paul P Lerner, Shmuel Sokolik, Vladimir Lerner, Anatoly Kreinin, Chanoch Miodownik
INTRODUCTION: Patients with Parkinson disease (PD) frequently experience visual hallucinations (VH). Visual hallucinations are most often viewed as an adverse effect of antiparkinsonian treatment. Possible treatments for this disturbance include a reduction of antiparkinsonian medications, adding atypical antipsychotics, or cholinesterase inhibitors. Some studies demonstrated that selective serotonin reuptake inhibitors may be an optional treatment for patients experiencing psychosis or agitation in dementia...
November 2017: Clinical Neuropharmacology
https://www.readbyqxmd.com/read/29035934/dextrometorphan-paroxetine-but-not-dronabinol-effective-for-treatment-resistant-aggression-and-agitation-in-an-elderly-patient-with-lewy-body-dementia
#12
Robert Wilhelm, Björn Ahl, Ion-George Anghelescu
No abstract text is available yet for this article.
October 13, 2017: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/28986942/management-of-behavioral-and-psychological-symptoms-of-dementia-bpsd-by-an-aroma-massage-with-acupressure-treatment-protocol-a-randomized-clinical-trial
#13
Jo Kamen Ka-Man Fung, Hector Wing-Hong Tsang
AIMS AND OBJECTIVES: This study evaluates the clinical effectiveness of a multi-component aroma-massage with an acupressure treatment protocol and compared it to cognitive training for the management of BPSD. BACKGROUND: Pharmacological interventions have been unsatisfactory in managing BPSD; thus, complementary and alternative medicine has been extensively researched to identify an adjunct safe and cost-effective intervention. DESIGN: This RCT utilized a three-arm parallel group design...
October 6, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28985387/neuropsychiatric-symptoms-and-psychotropic-drug-use-in-patients-with-dementia-in-general-practices
#14
Petra Borsje, Peter L B J Lucassen, Roland B Wetzels, Anne Margriet Pot, Raymond T C M Koopmans
Background: Neuropsychiatric symptoms (NPS) frequently occur in community-dwelling patients with dementia and they are also frequently prescribed psychotropic drugs. The prescription of psychotropic drugs has been found to be associated with the level of NPS. Data on NPS in patients with dementia in general practices are scarce. Objectives: The aim of this study was to assess the prevalence rates of NPS and psychotropic drug use (PDU) in patients with dementia in general practices...
July 14, 2017: Family Practice
https://www.readbyqxmd.com/read/28984606/the-use-of-music-playlists-for-people-with-dementia-a-critical-synthesis
#15
Sandra Garrido, Laura Dunne, Esther Chang, Janette Perz, Catherine J Stevens, Maggie Haertsch
The use of pre-recorded music to ease behavioral and psychological symptoms associated with dementia is popular in health-care contexts in both formal music therapy settings and in non-therapist led interventions. However, further understanding of how non-therapist led interventions compare to therapist led interventions is needed. This paper reviews 28 studies that used pre-recorded music with people with dementia using a critical interpretive synthesis model. Results revealed that pre-recorded music can be effective in reducing a variety of affective and behavioral symptoms, in particular agitation, even where a trained music therapist is not present...
2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28975291/antipsychotics-to-treat-agitation-or-psychosis-in-patients-with-dementia
#16
Daniel Yohanna, Adam S Cifu
No abstract text is available yet for this article.
September 19, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/28971511/relationship-between-speaking-english-as-a-second-language-and-agitation-in-people-with-dementia-living-in-care-homes-results-from-the-marque-managing-agitation-and-raising-quality-of-life-english-national-care-home-survey
#17
C Cooper, P Rapaport, S Robertson, L Marston, J Barber, M Manela, G Livingston
OBJECTIVE: As not speaking English as a first language may lead to increased difficulties in communication with staff and other residents, we (1) tested our primary hypotheses that care home residents with dementia speaking English as a second language experience more agitation and overall neuropsychiatric symptoms, and (2) explored qualitatively how staff consider that residents' language, ethnicity, and culture might impact on how they manage agitation. METHODS: We interviewed staff, residents with dementia, and their family carers from 86 care homes (2014-2015) about resident's neuropsychiatric symptoms, agitation, life quality, and dementia severity...
October 3, 2017: International Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/28936936/-treatment-of-dementia
#18
K Blom, G A H van den Elsen, H L Koek, J B Sanders, H C Kruithof, J A H R Claassen
- Treatment options for patients with dementia are limited. This article provides an overview of possible interventions, both pharmaceutical and non-pharmaceutical, for Alzheimer's disease, vascular dementia and mixed dementia.- Pharmaceutical treatment options include cholinesterase inhibitors, memantine and experimental medication. Cholinesterase inhibitors are only recommended for Alzheimer's disease and mixed dementia, not for vascular dementia or mild cognitive impairment. There is no proof of effectiveness for the other pharmaceutical options...
2017: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/28931452/factors-associated-with-appropriate-psychotropic-drug-prescription-in-nursing-home-patients-with-severe-dementia
#19
Klaas van der Spek, Raymond Tcm Koopmans, Martin Smalbrugge, Marjorie Hjmg Nelissen-Vrancken, Roland B Wetzels, Claudia Hw Smeets, Steven Teerenstra, Sytse U Zuidema, Debby L Gerritsen
BACKGROUND: We studied the patient and non-patients factors of inappropriate psychotropic drug (PD) prescription for neuropsychiatric symptoms (NPS) in nursing home patients with severe dementia. METHODS: In a cross-sectional study, the appropriateness of prescriptions was explored using the Appropriate Psychotropic drug use In Dementia (APID) index sum score. This index assesses information from medical records on indication, evaluation, dosage, drug-drug interactions, drug-disease interactions, duplications, and therapy duration...
September 21, 2017: International Psychogeriatrics
https://www.readbyqxmd.com/read/28927477/frequency-and-subgroups-of-neuropsychiatric-symptoms-in-mild-cognitive-impairment-and-different-stages-of-dementia-in-alzheimer-s-disease
#20
N Siafarikas, G Selbaek, T Fladby, J Šaltytė Benth, E Auning, D Aarsland
BACKGROUND: Neuropsychiatric symptoms (NPS), such as depression, apathy, agitation, and psychotic symptoms are common in mild cognitive impairment (MCI) and dementia in Alzheimer's disease (AD). Subgroups of NPS have been reported. Yet the relationship of NPS and their subgroups to different stages of cognitive impairment is unclear. Most previous studies are based on small sample sizes and show conflicting results. We sought to examine the frequency of NPS and their subgroups in MCI and different stages of dementia in AD...
September 20, 2017: International Psychogeriatrics
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