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https://www.readbyqxmd.com/read/28728352/the-association-between-physical-activity-and-atrial-fibrillation-applying-heaviside-function-in-survival-analysis-the-multi-ethnic-study-of-atherosclerosis-mesa
#1
Yaser Mokhayeri, Seyed Saeed Hashemi Nazari, Mohammad Ali Mansournia, Hamid Soori, Soheila Khodakarim
Objectives: Although the effect of physical activity (PA) on the incidence of atrial fibrillation (AF) has been studied, contradictory results have been reported. These seemingly different results may reflect alternate effects of different types of PA upon AF as well as gender interactions. Therefore, we aimed to evaluate the association of PA types namely total, moderate/vigorous, intentional, as well as walking pace on AF risk, in men and women. Methods: Using the MESA Typical Week Physical Activity Survey, three PA measures and walking pace among 6487 men and women aged 45-84 years were calculated...
June 18, 2017: Epidemiology and Health
https://www.readbyqxmd.com/read/28727907/novel-role-of-surfactant-protein-a-in-bacterial-sinusitis
#2
George T Noutsios, Amanda L Willis, Julie G Ledford, Eugene H Chang
BACKGROUND: Chronic rhinosinusitis (CRS) is a common inflammatory disorder of the upper airway characterized by chronic inflammation and significant sinonasal remodeling. CRS is comprised of 2 major subgroups, based on whether polyps are present or absent. In some cases, it is characterized by colonization with opportunistic pathogens such as Pseudomonas aeruginosa (PA), Staphylococcus aureus, and other bacteria. The innate immune system of the sinonasal epithelium is the first line of defense against inhaled pathogens...
July 20, 2017: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/28727801/proponent-or-collaborative-physician-perspectives-and-approaches-to-disease-modifying-therapies-in-sickle-cell-disease
#3
Nitya Bakshi, Cynthia B Sinha, Diana Ross, Kirshma Khemani, George Loewenstein, Lakshmanan Krishnamurti
Sickle cell disease (SCD) is an inherited blood disorder that primarily affects African-American and other ethnic minority populations. There are three available disease-modifying therapies for sickle cell disease: hydroxyurea (HU), bone marrow transplantation (BMT), and chronic blood transfusion (CBT). Since these treatments vary in their therapeutic intent, efficacy in preventing progression of the disease, short and long-term adverse effects, costs and patient burden, the decision-making process regarding these therapies is complicated for both the patient and healthcare provider...
2017: PloS One
https://www.readbyqxmd.com/read/28727796/effects-of-health-risk-assessment-and-counselling-on-physical-activity-in-older-people-a-pragmatic-randomised-trial
#4
Anna Marie Herghelegiu, André Moser, Gabriel Ioan Prada, Stephan Born, Matthias Wilhelm, Andreas E Stuck
BACKGROUND: Interventions to increase physical activity (PA) among older community-dwelling adults may be enhanced by using multidimensional health risk assessment (HRA) as a basis for PA counselling. METHODS: The study was conducted among nondisabled but mostly frail persons 65 years of age and older at an ambulatory geriatric clinic in Bucharest, Romania. From May to July 2014, 200 participants were randomly allocated to intervention and control groups. Intervention group participants completed an initial HRA questionnaire and then had monthly counselling sessions with a geriatrician over a period of six months that were aimed at increasing low or maintaining higher PA...
2017: PloS One
https://www.readbyqxmd.com/read/28727643/improving-early-adolescent-girls-motor-skill-a-cluster-randomized-controlled-trial
#5
Natalie Lander, Philip J Morgan, Jo Salmon, Lisa M Barnett
BACKGROUND: Physical activity (PA) levels decline substantially during adolescence, and are consistently lower in girls. Competency in a range of fundamental movement skills (FMS) may serve as a protective factor for the decline in PA typically observed in adolescent girls; yet, girls' mastery in FMS is low. Whilst interventions can improve FMS, there is a lack of interventions targeting girls, and very few are conducted in high schools. Additionally, interventions are usually conducted by researchers, not teachers, and thus have little chance of being embedded into curricula...
July 19, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28726878/noninvasive-photoacoustic-measurement-of-glucose-by-data-fusion
#6
Ruochong Zhang, Fei Gao, Xiaohua Feng, Siyu Liu, Rahul Kishor, Yunqi Luo, Yuanjin Zheng
We proposed a novel noninvasive method for glucose detection using a photoacoustic (PA) technique utilizing both the peak-to-peak value and peak arrival time delay information. Without increasing apparatus and system complexity, we demonstrated the accuracy enhancement of 29.5% and 33.63% for high (0-7 g dL(-1)) and low (0-350 mg dL(-1)) concentration of glucose solution, compared to conventional amplitude-based prediction.
July 20, 2017: Analyst
https://www.readbyqxmd.com/read/28726347/md2-blockage-protects-obesity-induced-vascular-remodeling-via-activating-ampk-nrf2
#7
Lintao Wang, Jibo Han, Peiren Shan, Shengban You, Xuemei Chen, Yiyi Jin, Jingying Wang, Weijian Huang, Yi Wang, Guang Liang
OBJECTIVE: Obesity and increased free fatty acid (FFA) levels are tightly linked with vascular oxidative stress and remodeling. Myeloid differentiation 2 (MD2), an important protein in innate immunity, is requisite for endotoxin lipopolysaccharide responsiveness. This study shows that palmitic acid (PA) also bonds to MD2, initiating cardiac inflammatory injury. However, it is not clear whether MD2 plays a role in noninflammatory systems such as obesity- and FFA-related oxidative stress involved in vascular remodeling and injury...
July 20, 2017: Obesity
https://www.readbyqxmd.com/read/28726276/the-colonic-groove-of-the-plains-viscacha-lagostomus-maximus-histochemical-evidence-of-an-abrupt-change-in-the-glycosylation-pattern-of-goblet-cells
#8
María Florencia Tano de la Hoz, Mirta Alicia Flamini, Carolina Natalia Zanuzzi, Alcira Ofelia Díaz
The ascending colon of most rodent species shows a longitudinal colonic groove that works as a retrograde transport pathway for a mixture of bacteria and mucus toward the cecum. We describe the morphology and glycosylation pattern of the colonic groove of Lagostomus maximus to analyze the role of mucins in this anatomical feature. We also studied the distribution pattern of the interstitial cells of Cajal (ICC) to evaluate their regulatory influence on gut motility. The groove originated near the cecocolic junction and extended along the mesenteric side of the ascending colon, limited at both ends by nonpapillated ridges...
July 20, 2017: Journal of Morphology
https://www.readbyqxmd.com/read/28724983/bio-inspired-interlocking-random-3-d-structures-for-tactile-and-thermal-sensing
#9
Long Pu, Rohit Saraf, Vivek Maheshwari
Hierarchical nanostructures are tailored and used routinely in nature to accomplish tasks with high performance. Their formation in nature is accomplished without the use of any patterning process. Inspired by the performance of such structures, we have combined 2-D nanosheets with 1-D nanorods for functioning as electronic skin. These structures made in high density without any patterning process can be easily assembled over large areas. They can sense pressures as low as 0.4 Pa, with a response time in milliseconds...
July 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28724420/legal-access-to-medications-a-threat-to-brazil-s-public-health-system
#10
Ana Luiza Chieffi, Rita De Cassia Barata Barradas, Moisés Golbaum
BACKGROUND: In Brazil, health is fundamental human right guaranteed by the Constitution of 1988, which created the Brazilian Universal Health System (Sistema Único de Saúde - SUS). The SUS provides medications for outpatient care via policy of pharmaceutical assistance (PA) programmes. Despite the advances in PA policies which include the improvement in access to medications, there has been a significant increase in lawsuits related to health products and services. This study aimed to characterize the medication processes filed between 2010 and 2014 against the Secretary of State for Health of São Paulo (State Health Department of São Paulo - SES/SP), in Brazil, following PA policies...
July 19, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28723919/level-of-physical-activity-and-aerobic-capacity-associate-with-quality-of-life-in-patients-with-temporal-lobe-epilepsy
#11
Nathalia Volpato, Juliana Kobashigawa, Clarissa Lin Yasuda, Simoni Thiemi Kishimoto, Paula Teixeira Fernandes, Fernando Cendes
Epilepsy is more than seizures and includes a high risk of comorbidities and psychological disorders, leading to poor quality of life (QOL). Earlier studies have showed a sedentary lifestyle in people with epilepsy (PWE), which could contribute to poorer health and psychological problems. The purpose of the present study was to compare habits of physical activity (PA), aerobic capacity, and QOL between PWE and healthy controls in order to identify the necessity of intervention of habits and information on physical exercise (PE) and to better understand the importance of PE for PWE...
2017: PloS One
https://www.readbyqxmd.com/read/28723844/associations-of-physical-activity-intensities-with-markers-of-insulin-sensitivity
#12
Charlotte Jelleyman, Charlotte L Edwardson, Joseph Henson, Laura J Gray, Alex V Rowlands, Kamlesh Khunti, Melanie J Davies, Thomas Yates
BACKGROUND: Objectively measured physical activity (PA) intensity has traditionally been categorised as light, moderate and vigorous using laboratory calibrated cut-points. The relative contribution of time spent across a spectrum of accelerometer-determined intensities on health outcomes is less clear. PURPOSE: To assess the relationship between objectively measured PA intensity on a continuous scale and markers of insulin sensitivity. METHODS: Participants at high risk of type 2 diabetes were recruited from primary care (Leicestershire, UK)...
July 19, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28723836/subjective-versus-objective-estimated-cardiovascular-disease-risk-and-adherence-to-physical-activity-in-african-american-women
#13
Nadia Robinson, Arlene Miller, JoEllen Wilbur, Louis Fogg
BACKGROUND: Cardiovascular disease (CVD) is the leading cause of death for African American (AA) women in the United States. Despite high prevalence of CVD risk factors, AA women perceive their CVD risk as low. OBJECTIVE: Our objectives were to (1) identify relationships between subjective (self-reported perceived) CVD risk and objective CVD risk estimated by the American College of Cardiology/American Heart Association atherosclerotic CVD (ASCVD) risk estimator, (2) identify demographic and psychosocial factors associated with subjective perceived risk and discrepancy with objective estimated CVD risk, and (3) determine whether subjective perceived CVD risk was associated with physical activity (PA) adherence...
July 18, 2017: Journal of Cardiovascular Nursing
https://www.readbyqxmd.com/read/28723305/prevalence-of-primary-aldosteronism-without-hypertension-in-the-general-population-results-in-shika-study
#14
Shigehiro Karashima, Mitsuhiro Kometani, Hiromasa Tsujiguchi, Hiroki Asakura, Shigeru Nakano, Mikiya Usukura, Shunsuke Mori, Masashi Ohe, Toshitaka Sawamura, Rika Okuda, Akinori Hara, Toshinari Takamura, Masakazu Yamagishi, Hiroyuki Nakamura, Yoshiyu Takeda, Takashi Yoneda
OBJECTIVE: Recent studies have reported a high prevalence of primary aldosteronism (PA) among hypertensive patients. However, few data exist regarding the prevalence of PA in the general population. Therefore, we examined the prevalence of PA in the general population including normotensive subjects. METHODS: Plasma renin activity (ng/mL/hr), plasma aldosterone concentration (pg/mL) and aldosterone renin ratio (ARR) were determined in 309 subjects aged >40 years in Horimatsu and Higashi-Matsuho district, Shika-machi, Ishikawa, Japan...
July 19, 2017: Clinical and Experimental Hypertension: CHE
https://www.readbyqxmd.com/read/28723182/cross-linked-gold-nanoparticle-membrane-resonators-as-microelectromechanical-vapor-sensors
#15
Hendrik Schlicke, Malte Behrens, Clemens J Schröter, Gregor T Dahl, Hauke Hartmann, Tobias Vossmeyer
We report a novel approach for the detection of volatile compounds employing electrostatically driven drumhead resonators as sensing elements. The resonators are based on freestanding membranes of alkanedithiol cross-linked gold nanoparticles (GNPs), which are able to sorb analytes from the gas phase. Under reduced pressure, the fundamental resonance frequency of a resonator is continuously monitored while the device is exposed to varying partial pressures of toluene, 4-methylpentan-2-one, 1-propanol, and water...
April 28, 2017: ACS Sensors
https://www.readbyqxmd.com/read/28723138/hand-held-femtogram-detection-of-hazardous-picric-acid-with-hydrophobic-ag-nanopillar-sers-substrates-and-mechanism-of-elasto-capillarity
#16
Aron Hakonen, FengChao Wang, Per Ola Andersson, Håkan Wingfors, Tomas Rindzevicius, Michael Stenbæk Schmidt, Venugopal Rao Soma, Shicai Xu, YingQi Li, Anja Boisen, HengAn Wu
Picric acid (PA) is a severe environmental and security risk due to its unstable, toxic, and explosive properties. It is also challenging to detect in trace amounts and in situ because of its highly acidic and anionic character. Here, we assess sensing of PA under nonlaboratory conditions using surface-enhanced Raman scattering (SERS) silver nanopillar substrates and hand-held Raman spectroscopy equipment. The advancing elasto-capillarity effects are explained by molecular dynamics simulations. We obtain a SERS PA detection limit on the order of 20 ppt, corresponding attomole amounts, which together with the simple analysis methodology demonstrates that the presented approach is highly competitive for ultrasensitive analysis in the field...
February 24, 2017: ACS Sensors
https://www.readbyqxmd.com/read/28723074/paper-based-bimodal-sensor-for-electronic-skin-applications
#17
Minhyun Jung, Kyungkwan Kim, Bumjin Kim, Haena Cheong, Kwanwoo Shin, Oh-Sun Kwon, Jong-Jin Park, Sanghun Jeon
We present the development of a flexible bimodal sensor using a paper platform and ink-jet printing method, which are suited for low-cost fabrication processes and realization of flexible devices. In this study, we employed a vertically stacked bimodal device architecture in which a temperature sensor is stacked on top of a pressure sensor and operated on different principles, allowing the minimization of interference effects. For the temperature sensor placed in the top layer, we used the thermoelectric effect and formed a closed-loop thermocouple composed of two different printable inks: conductive PEDOT:PSS and silver nanoparticles on a flexible paper platform, and obtained temperature-sensing capability over a wide range (150 ℃)...
July 19, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28722772/understanding-leisure-time-physical-activity-voices-of-people-with-ms-who-have-moderate-to-severe-disability-and-their-family-caregivers
#18
Afolasade Fakolade, Julie Lamarre, Amy Latimer-Cheung, Trisha Parsons, Sarah A Morrow, Marcia Finlayson
BACKGROUND: Physical activity (PA) is beneficial for all people, yet people affected by multiple sclerosis (MS) find regular PA challenging. These people may include individuals with the disease who have moderate-to-severe disability and their family caregivers. For researchers and clinicians to effectively promote PA among caregiver/care-recipient dyads with moderate-to-severe MS, a comprehensive understanding of the shared PA experiences of these dyads would be beneficial. OBJECTIVE: We explored shared experiences of caregiver/care-recipient dyads affected by moderate-to-severe MS about PA and directions for intervention...
July 19, 2017: Health Expectations: An International Journal of Public Participation in Health Care and Health Policy
https://www.readbyqxmd.com/read/28722154/application-of-headspace-solid-phase-microextraction-followed-by-gas-chromatography-coupled-with-mass-spectrometry-spme-gc-ms-to-determine-esters-of-carboxylic-acids-and-other-volatile-compounds-in-d-maculatus-and-d-ater-lipids
#19
Magdalena Cerkowniak, Mieczysława I Boguś, Emilia Włóka, Piotr Stepnowski, Marek Gołębiowski
A constant problem in veterinary medicine, human healthcare, agriculture, forestry or horticulture is the large number of pests, and the lack of effective methods to combat them which cause no harm to the rest of the environment. It is recommended and desired to reduce the use of chemicals and increase the use of agents based on the knowledge acquired in the field of biology, chemistry, and agrochemicals. To learn the defense mechanisms of insects we should consider not only the site of their physiological ability to protect against external factors (cuticle), but also check the possibility of chemical protection, formed by all compounds on the surface and in the body of insects...
July 19, 2017: Biomedical Chromatography: BMC
https://www.readbyqxmd.com/read/28722133/rheological-characterization-of-gluten-from-triticale-x-triticosecale-wittmack
#20
Anna Pruska-Kędzior, Agnieszka Makowska, Zenon Kędzior, Bolesław P Salmanowicz
BACKGROUND: Triticale gluten still remains very poorly characterized rheologically. In this study the mechanical spectra of gluten isolated from four triticale cultivars were registered and fitted with Cole-Cole functions yielding the viscoelastic plateau parameters. Master spectra were calculated. Retardation test was performed and used to calculate the composite mechanical spectra and the width of viscoelastic plateau l. Protein fractional composition of triticale flour and gluten was studied using capillary zone electrophoresis...
July 19, 2017: Journal of the Science of Food and Agriculture
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