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https://www.readbyqxmd.com/read/28932875/-severe-cutaneous-drug-reactions-in-children
#1
REVIEW
M Mockenhaupt
Among severe drug reactions in children, besides Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN), a specific form of hypersensitivity syndrome which is nowadays known as "drug reaction with eosinophilia and systemic symptoms" (DRESS) has to be mentioned. Whereas SJS/TEN is considered one reaction entity of different severity, DRESS has to be distinguished from SJS/TEN but also from other severe exanthems due to multiorgan involvement. Although SJS/TEN is generally referred to as a drug reaction, only about 75% of all cases are actually caused by medications and in children it is only about 50%...
September 20, 2017: Der Hautarzt; Zeitschrift Für Dermatologie, Venerologie, und Verwandte Gebiete
https://www.readbyqxmd.com/read/28914958/assessment-of-histopathological-features-of-maculopapular-viral-exanthem-and-drug-induced-exanthem
#2
Sanjay Singh, Sujay Khandpur, Sudheer Arava, Ramashankar Rath, M Ramam, Manoj Singh, Vinod K Sharma, S K Kabra
Maculopapular exanthem (MPE) is defined as a skin eruption consisting of macules and papules which does not form a scale. When associated with oral lesions, the term exanthem with 'enanthem' term is employed (1). Viral infection and drug reaction are the commonest causes of exanthem.
September 15, 2017: Journal of Cutaneous Pathology
https://www.readbyqxmd.com/read/28893877/superimposed-lateralized-exanthem-in-a-30-year-old-woman
#3
Carmen María Alcántara-Reifs, Rafael Salido-Vallejo
No abstract text is available yet for this article.
September 11, 2017: CMAJ: Canadian Medical Association Journal, Journal de L'Association Medicale Canadienne
https://www.readbyqxmd.com/read/28856664/iga-multiple-myeloma-in-a-patient-with-an-igg-pemphigus-foliaceus-like-exanthem
#4
Nayoung Lee, Stephen J Lockwood, Paul Richardson, Claudia Paba-Prada, Arturo P Saavedra
No abstract text is available yet for this article.
August 30, 2017: International Journal of Dermatology
https://www.readbyqxmd.com/read/28764276/can-unilateral-pityriasis-rosea-be-considered-a-form-of-superimposed-lateralized-exanthem
#5
Francesco Drago, Giulia Ciccarese, Aurora Parodi
No abstract text is available yet for this article.
June 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28754336/unilateral-laterothoracic-exanthem
#6
Belén Lozano-Masdemont
No abstract text is available yet for this article.
July 25, 2017: Medicina Clínica
https://www.readbyqxmd.com/read/28545483/encephalitis-associated-with-human-herpesvirus-7-infection-in-an-immunocompetent-adult
#7
Mónica Parra, Adoración Alcala, Cristina Amoros, Anna Baeza, Antonio Galiana, David Tarragó, Miguel Ángel García-Quesada, Victoria Sánchez-Hellín
BACKGROUND: Primary Human herpesvirus-7 (HHV-7) infection usually occurs during childhood and causes several clinical manifestations: mainly exanthem subitum (roseola infantum), followed by a lifelong latent state with possible reactivation in case of immunodeficiency. Nevertheless, some considerably different approaches exist regarding the natural history of HHV-7 and the possible consequences of HHV-7 infection in immunocompetent adults. In particular, little is known about its pathogenic role in central nervous system (CNS) disease in nonimmunosuppressed adults...
May 25, 2017: Virology Journal
https://www.readbyqxmd.com/read/28413059/viral-exanthems-an-update-on-laboratory-testing-of-the-adult-patient
#8
REVIEW
Abraham M Korman, Ali Alikhan, Benjamin H Kaffenberger
Although classic viral exanthems of childhood are well described, they are rarely differentiated in adults. Laboratory techniques for viral identification have advanced without substantial literature to suggest how a dermatologist ought to conduct a cost-effective and diagnostic viral panel. Certain clinical features such as petechiae, vesicles, and dusky macular or morbilliform exanthems point strongly toward a viral exanthem. Differentiation of drug and viral causes of morbilliform eruptions has proven difficult...
March 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/28403057/fever-in-stevens-johnson-syndrome-and-toxic-epidermal-necrolysis-in-pediatric-cases-laboratory-work-up-and-antibiotic-therapy
#9
Maren Paulmann, Maja Mockenhaupt
Fever is a symptom that often accompanies skin eruptions, especially in children. It can be a sign of an infectious condition presenting with exanthems or it may precede an exanthematous eruption. Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are severe reactions affecting skin and mucosa with blisters and erosions. High fever occurs in these conditions, frequently before the skin and/or mucosa is affected.
May 2017: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/28345391/a-retrospective-study-on-rapid-plasma-reagin-testing-in-patients-with-pityriasis-rosea
#10
Pierre Halteh, Shari R Lipner
Pityriasis rosea (PR) is an acute self-limited exanthem characterized by oval erythematous patches with scale and may be difficult to differentiate from secondary syphilis. A rapid plasma reagin (RPR) test can be used to rule in secondary syphilis with high sensitivity and specificity. A retrospective study was performed on patients at Weill Cornell Medicine, who were diagnosed with PR from 2000 to 2016 and also received RPR testing at the time of diagnosis. The objective was to assess the frequency of secondary syphilis when the initial clinical impression was PR...
January 1, 2017: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/28315874/multiple-drug-hypersensitivity
#11
REVIEW
Werner J Pichler, Yuttana Srinoulprasert, James Yun, Oliver Hausmann
Multiple drug hypersensitivity (MDH) is a syndrome that develops as a consequence of massive T-cell stimulations and is characterized by long-lasting drug hypersensitivity reactions (DHR) to different drugs. The initial symptoms are mostly severe exanthems or drug rash with eosinophilia and systemic symptoms (DRESS). Subsequent symptoms due to another drug often appear in the following weeks, overlapping with the first DHR, or months to years later after resolution of the initial presentation. The second DHR includes exanthema, erythroderma, DRESS, Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN), hepatitis, and agranulocytosis...
2017: International Archives of Allergy and Immunology
https://www.readbyqxmd.com/read/28214315/exanthem-und-ekzem-bei-einem-anderthalbj%C3%A3-hrigen-jungen
#12
Frederieke Thielking, Regina Fölster-Holst
No abstract text is available yet for this article.
February 2017: Journal der Deutschen Dermatologischen Gesellschaft, Journal of the German Society of Dermatology: JDDG
https://www.readbyqxmd.com/read/28194482/-paraviral-exanthems
#13
REVIEW
R Fölster-Holst, V Zawar, A Chuh
Paraviral exanthems are distinct skin diseases due to infections with different viruses. Although no virus has been identified so far in some exanthems, the main age of manifestation, the clinical course of the exanthem, and the extracutaneous symptoms are suggestive for a viral genesis. While many viral infections are a direct result of the infection, paraviral exanthems reflect the response of the immune system to the infectious pathogens. Viruses cannot be identified in the skin. Typical paraviral exanthems include Gianotti-Crosti syndrome, pityriasis rosea, pityriasis lichenoides, papular-purpuric gloves and sock syndrome, and asymmetrical periflexural exanthema...
March 2017: Der Hautarzt; Zeitschrift Für Dermatologie, Venerologie, und Verwandte Gebiete
https://www.readbyqxmd.com/read/28094164/disorders-characterized-by-predominant-or-exclusive-dermal-inflammation
#14
REVIEW
Mark R Wick
Some cutaneous inflammatory disorders are typified by a predominant or exclusive localization in the dermis. They can be further subdivided by the principal cell types into lymphocytic, neutrophilic, and eosinophilic infiltrates, and mixtures of them are also seen in a proportion of cases. This review considers such conditions. Included among the lymphoid lesions are viral exanthems, pigmented purpuras, gyrate erythemas, polymorphous light eruption, lupus tumidus, and cutaneous lymphoid hyperplasia. Neutrophilic infiltrates are represented by infections, Sweet syndrome, pyoderma gangrenosum, and hidradenitis suppurativa, as well as a group of so-called "autoinflammatory" dermatitides comprising polymorphonuclear leukocytes...
May 2017: Seminars in Diagnostic Pathology
https://www.readbyqxmd.com/read/28038854/-tache-noire-diagnostic-clue-in-a-febrile-exanthem
#15
Virginia Velasco-Tamariz, Fátima Tous-Romero, Alba Calleja-Algarra, Lidia Maroñas-Jiménez
No abstract text is available yet for this article.
December 27, 2016: Medicina Clínica
https://www.readbyqxmd.com/read/27996140/image-gallery-a-case-of-unilateral-laterothoracic-exanthem
#16
S H Woo, J Park
No abstract text is available yet for this article.
December 2016: British Journal of Dermatology
https://www.readbyqxmd.com/read/27992394/the-conundrum-in-the-diagnosis-and-management-of-atypical-fulminant-measles-in-a-leukemia-survivor-on-maintenance-chemotherapy
#17
James Guoxian Huang, Allen Eng Juh Yeoh, Paul Anantharajah Tambyah, Mas Isa Suhaila
We report the diagnostic and therapeutic challenges in an unusually fulminant presentation of measles, presenting as severe necrotizing bronchiolitis with secondary hemophagocytic lymphohistiocytosis (HLH) in the absence of classical clinical features in an immunocompromised host on maintenance chemotherapy. Our patient had presented with features of a viral pneumonitis without the classical exanthem, in combination with HLH. Although rhinovirus-induced HLH was highly unusual, the positive rhinovirus swab result had distracted us from the eventual diagnosis...
January 2017: Journal of Pediatric Hematology/oncology
https://www.readbyqxmd.com/read/27990380/kawasaki-disease-for-dermatologists
#18
REVIEW
Aman Gupta, Surjit Singh
Kawasaki disease (KD) is a systemic vasculitis that mostly affects children below the age of 5. The vasculitis involves arteries of medium size, especially the coronaries. Various etiologies have been proposed including association with micro-organisms, bacterial superantigens, and genetic factors, however, the exact cause remains unknown. There is no specific laboratory test for KD. Diagnosis is clinical and depends upon the presence of fever for ≥5 days and 4 or more of five principal features, viz. polymorphous exanthem, extremity changes, mucosal changes involving the lips and oral cavity, bilateral bulbar conjunctival injection, and unilateral cervical lymphadenopathy...
November 2016: Indian Dermatology Online Journal
https://www.readbyqxmd.com/read/27845968/epidemiology-of-zika
#19
Carmen C Deseda
PURPOSE OF REVIEW: Zika virus (ZIKV) is the latest 'emerging virus' that has affected the Americas. First identified in the mid-20th century in Uganda, it was described as a vector arthropod-borne virus (arbovirus) and subsequently found capable of producing illness in humans. The illness was not different from other flavivirus infections and caused a relatively mild disease characterized by low-grade fever, nonspecific exanthem, nonpurulent conjunctivitis, and mild to moderate arthralgia...
February 2017: Current Opinion in Pediatrics
https://www.readbyqxmd.com/read/27701670/annular-eruptive-pseudoangiomatosis-and-adenovirus-infection-a-novel-clinical-variant-of-paraviral-exanthems-and-a-novel-virus-association
#20
Antonio Chuh, Rüdiger Panzer, Ann-Christine Rosenthal, Ehrhardt Proksch, Werner Kempf, Vijay Zawar, Helmuth Fickenscher, Regina Fölster-Holst
Eruptive pseudoangiomatosis is a distinct exanthem thought to be caused by viruses. The usual rash configu-ration is erythematous papules and macules. An association with echovirus infection has been reported. We present here one adult and one child with this exanthem, supported by clinical, histopathological, and immunohistochemical findings. Both patients presented with prodromal symptoms, widespread angioma-like macules in annular configuration, blanchable telangiectasia, followed by spontaneous remission in 6-8 weeks...
March 10, 2017: Acta Dermato-venereologica
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