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https://www.readbyqxmd.com/read/29349257/the-tyranny-of-the-averages-and-the-indiscriminate-use-of-risk-factors-in-public-health-the-case-of-coronary-heart-disease
#1
Juan Merlo, Shai Mulinari, Maria Wemrell, S V Subramanian, Bo Hedblad
Modern medicine is overwhelmed by a plethora of both established risk factors and novel biomarkers for diseases. The majority of this information is expressed by probabilistic measures of association such as the odds ratio (OR) obtained by calculating differences in average "risk" between exposed and unexposed groups. However, recent research demonstrates that even ORs of considerable magnitude are insufficient for assessing the ability of risk factors or biomarkers to distinguish the individuals who will develop the disease from those who will not...
December 2017: SSM—Population Health
https://www.readbyqxmd.com/read/29345573/precision-medicine-update-on-diagnosis-and-therapeutic-strategies-of-hepatocellular-carcinoma
#2
Qing Liang, Xiaoying Shen, Guangchun Sun
Recent advances in multiple omics technologies and the advent of massively parallel sequencing provide technical supports for the implementation of precision medicine. The precision medicine emphasizes that heterogeneous diseases can be well classified into more precise subtypes by the powerful detection methods and integration of clinical features, so that the clinicians should develop more accurate diagnosis and therapeutic strategies for the disease subtype population, in an effort to maximize the efficacy and minimize the unnecessary side effects...
January 16, 2018: Current Medicinal Chemistry
https://www.readbyqxmd.com/read/29334885/2016-united-kingdom-national-guideline-on-the-sexual-health-care-of-men-who-have-sex-with-men
#3
Dan Clutterbuck, David Asboe, Tristan Barber, Carol Emerson, Nigel Field, Stuart Gibson, Gwenda Hughes, Rachael Jones, Martin Murchie, Achyuta V Nori, Michael Rayment, Ann Sullivan
This guideline is intended for use in UK Genitourinary medicine clinics and sexual health services but is likely to be of relevance in all sexual health settings, including general practice and Contraception and Sexual Health (CASH) services, where men who have sex with men (MSM) seek sexual health care or where addressing the sexual health needs of MSM may have public health benefits. For the purposes of this document, MSM includes all gay, bisexual and all other males who have sex with other males and both cis and trans men...
January 1, 2018: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/29331970/is-there-a-social-gradient-of-sarcopenia-a-meta-analysis-and-systematic-review-protocol
#4
Darci Green, Gustavo Duque, Nick Fredman, Aoun Rizvi, Sharon Lee Brennan-Olsen
INTRODUCTION: Sarcopenia (or loss of muscle mass and function) is a relatively new area within the field of musculoskeletal research and medicine. Investigating whether there is a social gradient, including occupation type and income level, of sarcopenia, as observed for other diseases, will contribute significantly to the limited evidence base for this disease. This new information may inform the prevention and management of sarcopenia and widen the evidence base to support existing and future health campaigns...
January 13, 2018: BMJ Open
https://www.readbyqxmd.com/read/29327981/hiv-aids-outreach-curriculum-development-and-skills-training-to-health-and-information-professionals
#5
Gretchen M Kuntz, Nancy Schaefer, Hannah F Norton, Michele R Tennant
With funding from the National Library of Medicine HIV/AIDS Community Information Outreach Program (ACIOP), librarians at the University of Florida Health Sciences Libraries partnered with university and community groups to facilitate collaboration, develop new information resources, develop information-seeking skills, and raise general awareness surrounding HIV/AIDS risks, prevention, and treatment. This article describes the skills development elements of the project, including development and implementation of an HIV/AIDS information resource curriculum for health care providers, social services professionals, and public librarians within the project's partner organizations...
January 2018: Medical Reference Services Quarterly
https://www.readbyqxmd.com/read/29326013/a-cluster-of-multidrug-resistant-mycobacterium-tuberculosis-among-patients-arriving-in-europe-from-the-horn-of-africa-a-molecular-epidemiological-study
#6
Timothy M Walker, Matthias Merker, Astrid M Knoblauch, Peter Helbling, Otto D Schoch, Marieke J van der Werf, Katharina Kranzer, Lena Fiebig, Stefan Kröger, Walter Haas, Harald Hoffmann, Alexander Indra, Adrian Egli, Daniela M Cirillo, Jérôme Robert, Thomas R Rogers, Ramona Groenheit, Anne T Mengshoel, Vanessa Mathys, Marjo Haanperä, Dick van Soolingen, Stefan Niemann, Erik C Böttger, Peter M Keller
BACKGROUND: The risk of tuberculosis outbreaks among people fleeing hardship for refuge in Europe is heightened. We describe the cross-border European response to an outbreak of multidrug-resistant tuberculosis among patients from the Horn of Africa and Sudan. METHODS: On April 29 and May 30, 2016, the Swiss and German National Mycobacterial Reference Laboratories independently triggered an outbreak investigation after four patients were diagnosed with multidrug-resistant tuberculosis...
January 8, 2018: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/29302648/incidence-of-malaria-typhoid-co-infection-among-adult-population-in-unwana-community-afikpo-north-local-government-area-ebonyi-state-southeastern-nigeria
#7
O O Odikamnoro, I M Ikeh, F N Okoh, S C Ebiriekwe, I A Nnadozie, J O Nkwuda, G C Asobie
Background: Malaria and typhoid fever are two leading infections of poverty with serious health and socioeconomic impacts, and due to their geographical overlap, co-infections are very common. Their mimicking symptomatology often present with gross misdiagnosis and mistreatment. This study was carried out to determine the incidence of malaria and typhoid co-infections among adult population in Unwana Community, Afikpo-North Local Government Area of Ebonyi State. Materials and Methods: Three hundred and fifty (350) individuals were examined, their blood samples subjected to microscopic examination and widal agglutination tests, for identification of Plasmodium parasites and antibodies to Salmonella enterica serovar typhi respectively...
2018: African Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29300380/development-and-evaluation-of-a-genomics-training-program-for-community-health-workers-in-texas
#8
Lei-Shih Chen, Shixi Zhao, Donaji Stelzig, Shweta U Dhar, Tanya Eble, Yu-Chen Yeh, Oi-Man Kwok
PurposeGenomics services have the potential to reduce incidence and mortality of diseases by providing individualized, family health history (FHH)-based prevention strategies to clients. These services may benefit from the involvement of community health workers (CHWs) in the provision of FHH-based genomics education and services, as CHWs are frontline public health workers and lay health educators, who share similar ethnicities, languages, socioeconomic statuses, and life experiences with the communities they serve...
January 4, 2018: Genetics in Medicine: Official Journal of the American College of Medical Genetics
https://www.readbyqxmd.com/read/29297143/curse-of-fluorosis
#9
REVIEW
M M Patil, Bhavana B Lakhkar, Shailaja S Patil
Fluoride was identified to have caries preventive properties and was widely used for fluoridation of water since 1940, especially in developed countries. After this there was sudden increase in the use of fluorides in food items and in oral medicinal products like toothpastes and mouth washes. Inadvertent use of above has lead to increase in fluorosis as a public health problem. In many places high fluorides are naturally present in earth crust leading to high water fluoride content increasing the risk of fluorosis...
January 3, 2018: Indian Journal of Pediatrics
https://www.readbyqxmd.com/read/29295695/anticancer-properties-of-essential-oils-an-overview
#10
Milene Aparecida Andrade, Mariana Aparecida Braga, Pedro Henrique Souza Cesar, Marcus Vinicius Cardoso Trento, Mariana Araujo Esposito, Lucilene Fernandes Silva
BACKGROUND: Essential oils are complex mixtures of low molecular weight compounds extracted from plants. Their main constituents are terpenes and phenylpropanoids, which are responsible for their biological and pharmaceutical properties, such as insecticidal, parasiticidal, antimicrobial, antioxidant, anti-inflammatory, analgesic, antinociceptive, anticarcinogenic, and antitumor properties. Cancer is a complex genetic disease considered as a serious public health problem worldwide, accounting for more than 8 million deaths annually...
January 1, 2018: Current Cancer Drug Targets
https://www.readbyqxmd.com/read/29294791/mentoring-pediatric-victims-of-interpersonal-violence-reduces-recidivism
#11
Angela Lumba-Brown, Margie Batek, Pamela Choi, Martin Keller, Robert Kennedy
Pediatric interpersonal violence is a public health crisis resulting in morbidity and mortality and recidivism. St. Louis City and surrounding areas have the highest rates of youth interpersonal violence nationally. St. Louis Children's Hospital (SLCH) Social Work in conjunction with Pediatric Emergency Medicine established a novel emergency department (ED)-initiated program to determine whether co-location of services followed by outpatient mentoring reduced the rate of morbidity, mortality, and recidivism in youths experiencing interpersonal violence...
June 1, 2017: Journal of Interpersonal Violence
https://www.readbyqxmd.com/read/29288739/mapping-the-residual-incidence-of-taeniasis-and-cysticercosis-in-colombia-2009-2013-using-geographical-information-systems-implications-in-public-health-and-travel-medicine
#12
Alfonso J Rodríguez-Morales, María Camila Yepes-Echeverri, Wilmer F Acevedo-Mendoza, Hamilton A Marín-Rincón, Carlos Culquichicón, Esteban Parra-Valencia, Jaime A Cardona-Ospina, Ana Flisser
BACKGROUND: In Colombia, taeniasis and cysticercosis have been significantly reduced over the past decades, however still reported with implications for public health and travel medicine. METHODS: An observational, retrospective study, in which the incidence of taeniasis and cysticercosis (ICD-10 codes B68s/B69s) in Colombia, 2009-2013, was estimated based on data extracted from the Individual Health Records System (Registro Individual de Prestación de Servicios, RIPS) was performed...
December 27, 2017: Travel Medicine and Infectious Disease
https://www.readbyqxmd.com/read/29281497/poly-drug-use-of-prescription-medicine-among-people-with-opioid-use-disorder-in-china-a-systematic-review-and-meta-analysis
#13
Tongyu Wang, Jun Ma, Rujia Wang, Zhimin Liu, Jie Shi, Lin Lu, Yanping Bao
BACKGROUND: Opioid use disorder (OUD) causes substantial public health and social problems worldwide. Poly-drug use is common in people with OUD and increases morbidity and mortality. Investigation of the patterns and characteristics of poly-drug use of prescription medicine among opioid users is needed to develop appropriate prevention and intervention strategies. OBJECTIVES: To estimate the prevalence of poly-drug use of prescription medicine among people with OUD in China using meta-analysis...
December 27, 2017: Substance Use & Misuse
https://www.readbyqxmd.com/read/29276617/antimicrobial-resistance-in-human-populations-challenges-and-opportunities
#14
REVIEW
S Allcock, E H Young, M Holmes, D Gurdasani, G Dougan, M S Sandhu, L Solomon, M E Török
Antimicrobial resistance (AMR) is a global public health threat. Emergence of AMR occurs naturally, but can also be selected for by antimicrobial exposure in clinical and veterinary medicine. Despite growing worldwide attention to AMR, there are substantial limitations in our understanding of the burden, distribution and determinants of AMR at the population level. We highlight the importance of population-based approaches to assess the association between antimicrobial use and AMR in humans and animals. Such approaches are needed to improve our understanding of the development and spread of AMR in order to inform strategies for the prevention, detection and management of AMR, and to support the sustainable use of antimicrobials in healthcare...
2017: Glob Health Epidemiol Genom
https://www.readbyqxmd.com/read/29274715/no-133-prevention-of-rh-alloimmunization
#15
Karen Fung Kee Fung, Erica Eason
OBJECTIVE: To provide guidelines on use of anti-D prophylaxis to optimize prevention of rhesus (Rh) alloimmunization in Canadian women. OUTCOMES: Decreased incidence of Rh alloimmunization and minimized practice variation with regards to immunoprophylaxis strategies. EVIDENCE: The Cochrane Library and MEDLINE were searched for English-language articles from 1968 to 200 I, relating to the prevention of Rh alloimmunization. Search terms included: Rho(D) immune globulin, Rh iso- or aile-immunization, anti-D, anti-Rh, WinRho, Rhogam, and pregnancy...
January 2018: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/29258191/patient-safety-in-complementary-medicine-through-the-application-of-clinical-risk-management-in-the-public-health-system
#16
Elio G Rossi, Tommaso Bellandi, Marco Picchi, Sonia Baccetti, Maria Valeria Monechi, Catia Vuono, Federica Sabatini, Antonella Traversi, Mariella Di Stefano, Fabio Firenzuoli, Sara Albolino, Riccardo Tartaglia
Aim: To develop a systematic approach to detect and prevent clinical risks in complementary medicine (CM) and increase patient safety through the analysis of activities in homeopathy and acupuncture centres in the Tuscan region using a significant event audit (SEA) and failure modes and effects analysis (FMEA). Methods: SEA is the selected tool for studying adverse events (AE) and detecting the best solutions to prevent future incidents in our Regional Healthcare Service (RHS). This requires the active participation of all the actors and external experts to validate the analysis...
December 16, 2017: Medicines (Basel, Switzerland)
https://www.readbyqxmd.com/read/29249249/-what-s-new-in-internal-medicine
#17
L Fardet
As it is practiced in France, internal medicine meets the Anglo-Saxon definition of the specialty, ie doctors "equipped to handle the broad and comprehensive spectrum of illnesses that affect adults, and are recognized as experts in diagnosis, in treatment of chronic illness, and in health promotion and disease prevention - they are not limited to one type of medical problem or organ system". This 2017 "What's new in internal medicine" will consist of 2 parts, a first part on significant publications in the field of systemic and autoimmune diseases and a second part on more diverse publications (HIV, cancer, pregnancy, well-being...
December 2017: Annales de Dermatologie et de Vénéréologie
https://www.readbyqxmd.com/read/29233952/epidemiological-study-of-mortality-rate-from-alcohol-and-illicit-drug-abuse-in-iran
#18
Seyed Mohammad Sadegh Ghoreishi, Fatemeh Shahbazi, Seyed Davood Mirtorabi, Mohammad Reza Ghadirzadeh, Seyed Saeed Hashemi Nazari
BACKGROUND: The estimate of mortality associated with illicit opiate use provides useful information to those directing and monitoring local, national and international policies and programs. This study investigated the epidemiology of mortality due to the illegal consumption of narcotics and psychotropic substances in the Iran to provide evidence-based public health data for useful programs and actions aimed at preventing drug-related mortality. STUDY DESIGN: A cross-sectional study...
October 14, 2017: Journal of Research in Health Sciences
https://www.readbyqxmd.com/read/29227277/use-of-complementary-and-alternative-medicine-in-georgia
#19
I Nadareishvili, K Lunze, N Tabagari, A Beraia, G Pkhakadze
In Georgia, like in most countries globally, people commonly resort to complementary and alternative medicine (CAM). However, not much is known about CAM practices there. The aim of the study was to document common practices of CAM in Georgia and related patient attitudes. We collected data from peoples who commonly use CAM at 20 service provision centers in Georgia using cluster sampling from 300 patients. We admininstered a cross-sectional survey and conducted descriptive statistical analyses. People in Georgia use CAM either for prevention to improve general health (33%) or to treat chronic conditions (36%), spending about 25 Euros per month out of pocket...
November 2017: Georgian Medical News
https://www.readbyqxmd.com/read/29225195/strengthening-integration-of-clinical-and-public-health-systems-to-prevent-maternal-child-obesity-in-the-first-1-000days-a-collective-impact-approach
#20
Tiffany Blake-Lamb, Alexy Arauz Boudreau, Sarah Matathia, Etna Tiburcio, Meghan E Perkins, Brianna Roche, Milton Kotelchuck, Derri Shtasel, Sarah N Price, Elsie M Taveras
INTRODUCTION: Obesity interventions may be most effective if they begin in the earliest stages of life, support changes across family, clinical, and public health systems, and address socio-contextual factors. METHODS: The First 1000Days is a systematic program starting in early pregnancy lasting through the first 24months of infancy to prevent obesity among low-income mother-infant pairs in three community health centers in Massachusetts. The program uses a Collective Impact approach to create the infrastructure for sustained, system-wide changes for obesity prevention across early life clinical and public health services, including Obstetrics, Pediatrics, Adult Medicine, Behavioral Health, Nutrition, Community Health, the Women, Infants and Children (WIC) program, and the Maternal, Infant and Childhood Home Visiting program...
December 7, 2017: Contemporary Clinical Trials
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