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https://www.readbyqxmd.com/read/28227035/visualizing-patient-journals-by-combining-vital-signs-monitoring-and-natural-language-processing
#1
Adnan Vilic, John Asger Petersen, Karsten Hoppe, Helge B D Sorensen, Adnan Vilic, John Asger Petersen, Karsten Hoppe, Helge B D Sorensen, John Asger Petersen, Adnan Vilic, Karsten Hoppe, Helge B D Sorensen
This paper presents a data-driven approach to graphically presenting text-based patient journals while still maintaining all textual information. The system first creates a timeline representation of a patients' physiological condition during an admission, which is assessed by electronically monitoring vital signs and then combining these into Early Warning Scores (EWS). Hereafter, techniques from Natural Language Processing (NLP) are applied on the existing patient journal to extract all entries. Finally, the two methods are combined into an interactive timeline featuring the ability to see drastic changes in the patients' health, and thereby enabling staff to see where in the journal critical events have taken place...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226222/computer-simulations-of-intrinsically-disordered-proteins
#2
Song-Ho Chong, Prathit Chatterjee, Sihyun Ham
The investigation of intrinsically disordered proteins (IDPs) is a new frontier in structural and molecular biology that requires a new paradigm to connect structural disorder to function. Molecular dynamics simulations and statistical thermodynamics potentially offer ideal tools for atomic-level characterizations and thermodynamic descriptions of this fascinating class of proteins that will complement experimental studies. However, IDPs display sensitivity to inaccuracies in the underlying molecular mechanics force fields...
February 6, 2017: Annual Review of Physical Chemistry
https://www.readbyqxmd.com/read/28224100/early-infant-male-circumcision-systematic-review-risk-benefit-analysis-and-progress-in-policy
#3
Brian J Morris, Sean E Kennedy, Alex D Wodak, Adrian Mindel, David Golovsky, Leslie Schrieber, Eugenie R Lumbers, David J Handelsman, John B Ziegler
AIM: To determine whether recent evidence-based United States policies on male circumcision (MC) apply to comparable Anglophone countries, Australia and New Zealand. METHODS: Articles in 2005 through 2015 were retrieved from PubMed using the keyword "circumcision" together with 36 relevant subtopics. A further PubMed search was performed for articles published in 2016. Searches of the EMBASE and Cochrane databases did not yield additional citable articles. Articles were assessed for quality and those rated 2+ and above according to the Scottish Intercollegiate Grading System were studied further...
February 8, 2017: World Journal of Clinical Pediatrics
https://www.readbyqxmd.com/read/28222068/inhibition-of-cdk5-induces-cell-death-of-tumor-initiating-cells
#4
Melanie M Mandl, Siwei Zhang, Melanie Ulrich, Elisa Schmoeckel, Doris Mayr, Angelika M Vollmar, Johanna Liebl
BACKGROUND: Tumour-initiating cells (TICs) account for chemoresistance, tumour recurrence and metastasis, and therefore represent a major problem in tumour therapy. However, strategies to address TICs are limited. Recent studies indicate Cdk5 as a promising target for anti-cancer therapy and Cdk5 has recently been associated with epithelial-mesenchymal transition (EMT). However, a role of Cdk5 in TICs has not been described yet. METHODS: Expression of Cdk5 in human cancer tissue was analysed by staining of a human tissue microarray (TMA)...
February 21, 2017: British Journal of Cancer
https://www.readbyqxmd.com/read/28221185/antipyretic-therapy-in-critically-ill-septic-patients-a-systematic-review-and-meta-analysis
#5
Anne M Drewry, Enyo A Ablordeppey, Ellen T Murray, Carolyn R T Stoll, Sonya R Izadi, Catherine M Dalton, Angela C Hardi, Susan A Fowler, Brian M Fuller, Graham A Colditz
OBJECTIVE: This meta-analysis aimed to examine the impact of antipyretic therapy on mortality in critically ill septic adults. DATA SOURCES: Literature searches were implemented in Ovid Medline, Embase, Scopus, Cumulative Index of Nursing and Allied Health Literature, Cochrane Central Register of Controlled Trials, NHS Economic Evaluation Database, and ClinicalTrials.gov through February 2016. STUDY SELECTION: Inclusion criteria were observational or randomized studies of septic patients, evaluation of antipyretic treatment, mortality reported, and English-language version available...
February 17, 2017: Critical Care Medicine
https://www.readbyqxmd.com/read/28218890/peer-review-in-clinical-pharmacology-using-the-8-d-assessment
#6
Barry G Woodcock
The requirement for editors of clinical pharmacology journals to maintain an overview of the peer review process for manuscripts submitted can be facilitated by use of the 8-D Assessment. The 8-D Assessment comprises peer review criteria to determine if the:1. Design of the study, 2. Diagnoses employed, 3. Drug molecules involved, 4. Dosages applied, 5. Data collected, 6. Discussion of the findings, 7. Deductions made, and 8. Documentation are in accord with the objectives of the study and meet the requirements of evidence-based medicine...
March 2017: International Journal of Clinical Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/28215372/the-managing-epilepsy-well-network-advancing-epilepsy-self-management
#7
EDITORIAL
Martha Sajatovic, Barbara C Jobst, Ross Shegog, Yvan A Bamps, Charles E Begley, Robert T Fraser, Erica K Johnson, Dilip K Pandey, Rakale C Quarells, Peter Scal, Tanya M Spruill, Nancy J Thompson, Rosemarie Kobau
Epilepsy, a complex spectrum of disorders, affects about 2.9 million people in the U.S. Similar to other chronic disorders, people with epilepsy face challenges related to management of the disorder, its treatment, co-occurring depression, disability, social disadvantages, and stigma. Two national conferences on public health and epilepsy (1997, 2003) and a 2012 IOM report on the public health dimensions of epilepsy highlighted important knowledge gaps and emphasized the need for evidence-based, scalable epilepsy self-management programs...
March 2017: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/28206775/one-hundred-years-of-the-journal-of-applied-psychology-background-evolution-and-scientific-trends
#8
Steve W J Kozlowski, Gilad Chen, Eduardo Salas
To launch this Special Issue of the Journal of Applied Psychology celebrating the 1st century of the journal we conducted a review encompassing the background of the founding of the journal; a quantitative assessment of its evolution across the century; and an examination of trends examining article type, article length, authorship patterns, supplemental materials, and research support. The journal was founded in March of 1917 with hopeful optimism about the potential of psychology being applied to practical problems could enhance human happiness, well-being, and effectiveness...
February 16, 2017: Journal of Applied Psychology
https://www.readbyqxmd.com/read/28206774/cross-cultural-industrial-organizational-psychology-and-organizational-behavior-a-hundred-year-journey
#9
Michele J Gelfand, Zeynep Aycan, Miriam Erez, Kwok Leung
In celebration of the anniversary of the Journal of Applied Psychology (JAP), we take a hundred-year journey to examine how the science of cross-cultural industrial/organizational psychology and organizational behavior (CCIO/OB) has evolved, both in JAP and in the larger field. We review broad trends and provide illustrative examples in the theoretical, methodological, and analytic advances in CCIO/OB during 4 main periods: the early years (1917-1949), the middle 20th century (1950-1979), the later 20th century (1980-2000), and the 21st century (2000 to the present)...
February 16, 2017: Journal of Applied Psychology
https://www.readbyqxmd.com/read/28206773/a-century-of-progress-in-industrial-and-organizational-psychology-discoveries-and-the-next-century
#10
Eduardo Salas, Steve W J Kozlowski, Gilad Chen
In a century of research published in the Journal of Applied Psychology, we have seen significant advances in our science. The results of this science have broad applications to the workplace and implications for improving organizational effectiveness through a variety of avenues. Research has focused on understanding constructs, relationships, and processes at multiple levels, including individual, team, and organizational. A plethora of research methods and questions have driven this work, resulting in a nuanced understanding of what matters in the workplace...
February 16, 2017: Journal of Applied Psychology
https://www.readbyqxmd.com/read/28205551/applying-recovery-biomarkers-to-calibrate-self-report-measures-of-sodium-and-potassium-in-the-hispanic-community-health-study-study-of-latinos
#11
Y Mossavar-Rahmani, D Sotres-Alvarez, W W Wong, C M Loria, M D Gellman, L Van Horn, M H Alderman, J M Beasley, C M Lora, A M Siega-Riz, R C Kaplan, P A Shaw
Measurement error in assessment of sodium and potassium intake obscures associations with health outcomes. The level of this error in a diverse US Hispanic/Latino population is unknown. We investigated the measurement error in self-reported dietary intake of sodium and potassium and examined differences by background (Central American, Cuban, Dominican, Mexican, Puerto Rican and South American). In 2010-2012, we studied 447 participants aged 18-74 years from four communities (Miami, Bronx, Chicago and San Diego), obtaining objective 24-h urinary sodium and potassium excretion measures...
February 16, 2017: Journal of Human Hypertension
https://www.readbyqxmd.com/read/28202950/including-non-informative-parents-in-transmission-based-association-tests
#12
Hemant Kulkarni, Saurabh Ghosh
The classical transmission disequilibrium test (TDT) based on a trio design uses information only on the allele transmitted by a heterozygous parent at a marker locus as homozygous parents are non-informative about linkage. However, the phenotype of an offspring depends on the alleles transmitted by both parents, irrespective of whether the parents are homozygous or heterozygous, and hence carry useful information on association. In this article, we propose modifications to the TDT procedures by incorporating transmission data on both parents in an informative trio to explore possible gain in power in detecting association...
February 16, 2017: Journal of Human Genetics
https://www.readbyqxmd.com/read/28198969/celebrating-the-25-years-of-the-journal-of-applied-oral-science
#13
EDITORIAL
Karin Hermana Neppelenbroek, Vanessa Soares Lara
No abstract text is available yet for this article.
January 2017: Journal of Applied Oral Science: Revista FOB
https://www.readbyqxmd.com/read/28188199/back-to-the-future-revisiting-the-physiological-cost-of-negative-work-as-a-team-based-activity-for-exercise-physiology-students
#14
Matthew A Kilgas, Steven J Elmer
We implemented a team-based activity in our exercise physiology teaching laboratory that was inspired from Abbott et al.'s classic 1952 Journal of Physiology paper titled "The physiological cost of negative work." Abbott et al. connected two bicycles via one chain. One person cycled forward (muscle shortening contractions, positive work) while the other resisted the reverse moving pedals (muscle lengthening contractions, negative work), and the cost of work was compared. This study was the first to link human whole body energetics with isolated muscle force-velocity characteristics...
March 1, 2017: Advances in Physiology Education
https://www.readbyqxmd.com/read/28184149/can-caring-create-prejudice-an-investigation-of-positive-and-negative-intergenerational-contact-in-care-settings-and-the-generalisation-of-blatant-and-subtle-age-prejudice-to-other-older-people
#15
Lisbeth Drury, Dominic Abrams, Hannah J Swift, Ruth A Lamont, Katarina Gerocova
Caring is a positive social act, but can it result in negative attitudes towards those cared for, and towards others from their wider social group? Based on intergroup contact theory, we tested whether care workers' (CWs) positive and negative contact with old-age care home residents (CHRs) predicts prejudiced attitudes towards that group, and whether this generalises to other older people. Fifty-six CWs were surveyed about their positive and negative contact with CHRs and their blatant and subtle attitudes (humanness attributions) towards CHRs and older adults...
January 2017: Journal of Community & Applied Social Psychology
https://www.readbyqxmd.com/read/28183141/mammography-service-screening-and-breast-cancer-mortality-in-new-zealand-a-national-cohort-study-1999-2011
#16
Stephen Morrell, Richard Taylor, David Roder, Bridget Robson, Marli Gregory, Kirsty Craig
BACKGROUND: This breast cancer mortality evaluation of service screening mammography in New Zealand, the first since commencement of screening in 1999, applies to the 1999-2011 diagnostic period. Individual-level linked information on mammography screening, breast cancer diagnosis and breast cancer mortality is used to analyse differences in breast cancer mortality according to participation in organised screening mammography, as provided by BreastScreen Aotearoa (BSA). METHODS: Women were followed from the time they became eligible for screening, from age 50 years (1999-2004) and 45 years (⩾2004)...
February 9, 2017: British Journal of Cancer
https://www.readbyqxmd.com/read/28182465/one-hundred-years-of-work-design-research-looking-back-and-looking-forward
#17
Sharon K Parker, Frederick P Morgeson, Gary Johns
In this article we take a big picture perspective on work design research. In the first section of the paper we identify influential work design articles and use scientific mapping to identify distinct clusters of research. Pulling this material together, we identify five key work design perspectives that map onto distinct historical developments: (a) sociotechnical systems and autonomous work groups, (b) job characteristics model, (c) job demands-control model, (d) job demands-resources model, and (e) role theory...
February 9, 2017: Journal of Applied Psychology
https://www.readbyqxmd.com/read/28182464/reflections-on-the-journal-of-applied-psychology-for-1997-to-2002
#18
Kevin R Murphy
Major trends in articles published during my term as Editor (1997-2000) are reviewed, including the number of articles received (approximately 500-600 per year) and the types of articles published. More than half of the articles published during this period fell into six broad categories: job attitudes and affect (82 articles); individual differences and measurement (52 articles); forensic psychology (50 articles); diversity and discrimination (46 articles); research methods, design, and analysis (41 articles); and performance appraisal and performance management (41 articles)...
February 9, 2017: Journal of Applied Psychology
https://www.readbyqxmd.com/read/28182463/reflections-on-the-journal-of-applied-psychology-for-2009-to-2014-infrastructure-operations-innovations-impact-evolution-and-desirable-directions
#19
Steve W J Kozlowski
In this reflection on my experiences as editor of the Journal of Applied Psychology, I consider 6 foci including (a) information on the background, infrastructure, and mechanics of running this top-tier journal; (b) statistics on journal operations across the 7 years of editorial activity (i.e., incoming plus 6 years on the masthead); (c) innovations that my senior editorial team introduced (i.e., transparency via supplemental materials, revival of monographs, initiation of integrative conceptual reviews); (d) impact and influence with respect to articles, authors, and institutions; (e) latent sematic analysis findings to illustrate the evolution and change of journal content over a 33-year comparison period (i...
February 9, 2017: Journal of Applied Psychology
https://www.readbyqxmd.com/read/28182462/reflections-on-the-journal-of-applied-psychology-for-2003-to-2008
#20
Sheldon Zedeck
The topic and theme content of the articles published during my term as editor of the Journal of Applied Psychology (2003-2008) are presented and discussed. The analysis of the content and trends is discussed in the context of attempts by my editorial team to influence what content was to be considered for publication as well as to engage in special efforts to generate more "theory" as well as alternative methodological approaches (e.g., qualitative data, content analysis, and the like) into the journal. The bigger issue for the perspective is whether the editorial team can influence what is published (yes) as opposed to what is researched (unlikely)...
February 9, 2017: Journal of Applied Psychology
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