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PEC II Block

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https://www.readbyqxmd.com/read/28932733/pectoral-nerve-block-pecs-block-with-sedation-for-breast-conserving-surgery-without-general-anesthesia
#1
Eun-Jin Moon, Seung-Beom Kim, Jun-Young Chung, Jeong-Yoon Song, Jae-Woo Yi
Most regional anesthesia in breast surgeries is performed as postoperative pain management under general anesthesia, and not as the primary anesthesia. Regional anesthesia has very few cardiovascular or pulmonary side-effects, as compared with general anesthesia. Pectoral nerve block is a relatively new technique, with fewer complications than other regional anesthesia. We performed Pecs I and Pec II block simultaneously as primary anesthesia under moderate sedation with dexmedetomidine for breast conserving surgery in a 49-year-old female patient with invasive ductal carcinoma...
September 2017: Annals of Surgical Treatment and Research
https://www.readbyqxmd.com/read/28890559/comparison-of-the-post-operative-analgesic-effect-of-paravertebral-block-pectoral-nerve-block-and-local-infiltration-in-patients-undergoing-modified-radical-mastectomy-a-randomised-double-blind-trial
#2
Kartik Syal, Ankita Chandel
BACKGROUND AND AIMS: Paravertebral block, pectoral nerve (Pecs) block and wound infiltration are three modalities for post-operative analgesia following breast surgery. This study compares the analgesic efficacy of these techniques for post-operative analgesia. METHODS: Sixty-five patients with American Society of Anesthesiologists' physical status 1 or 2 undergoing modified radical mastectomy with axillary dissection were recruited for the study. All patients received 21 mL 0...
August 2017: Indian Journal of Anaesthesia
https://www.readbyqxmd.com/read/28654558/the-efficacy-of-ultrasound-guided-type-ii-pectoral-nerve-blocks-in-perioperative-pain-management-for-immediate-reconstruction-after-modified-radical-mastectomy-a-prospective-randomized-study
#3
Kaiyuan Wang, Xiaobei Zhang, Tingting Zhang, Hui Yue, Shan Sun, Hongwei Zhao, Peng Zhou
OBJECTIVES: The pectoral nerves (Pecs) II block is a technique that places local anesthetic between the thoracic muscles to block the axillary and breast regions. This study aimed to compare the quality of perioperative analgesia and side effects of the Pecs II block under general anesthesia versus general anesthesia alone in immediate unilateral breast reconstruction with an implant and latissimus dorsi (LD) flap after modified radical mastectomy. METHODS: Sixty-four patients scheduled for immediate breast reconstruction after modified radical mastectomy were randomly allocated into the Pecs II block under general anesthesia group (Group P, n=32) or the general anesthesia alone group (Group G, n=32)...
June 16, 2017: Clinical Journal of Pain
https://www.readbyqxmd.com/read/28625445/prospective-double-blind-randomized-placebo-controlled-clinical-trial-of-the-pectoral-nerves-pecs-block-type-ii
#4
Barbara Versyck, Geert-Jan van Geffen, Patrick Van Houwe
STUDY OBJECTIVE: The aim of this clinical trial was to test the hypothesis whether adding the pectoral nerves (Pecs) block type II to the anesthetic procedure reduces opioid consumption during and after breast surgery. DESIGN: A prospective randomized double blind placebo-controlled study. SETTING: A secondary hospital. PATIENTS: 140 breast cancer stage 1-3 patients undergoing mastectomy or tumorectomy with sentinel node or axillary node dissection...
August 2017: Journal of Clinical Anesthesia
https://www.readbyqxmd.com/read/28554710/the-pecs-ii-block-as-a-major-analgesic-component-for-clavicle-operations-a-description-of-7-case-reports
#5
J B Schuitemaker R, X Sala-Blanch, C L Rodriguez-Pérez, J T Mayoral R, L A López-Pantaleon, A P Sánchez-Cohen
Clavicle fractures correspond to 35% of traumatic fractures of the shoulder girdle. Regional anaesthesia has shown better analgesic results than systemic treatment for perioperative management. Innervation of the clavicle is complex, at present its knowledge raises controversy. The lateral pectoral nerve through the innervating musculature predominantly participates in the lateral and anterior part of the clavicle. The following report of 7 cases describes the effective postoperative analgesia of modified PEC II block in patients with middle third clavicle fracture or acromioclavicular dislocation who underwent a modified PEC II block for postoperative pain management, in the context of a multimodal analgesia...
May 26, 2017: Revista Española de Anestesiología y Reanimación
https://www.readbyqxmd.com/read/28367293/thoracic-interfascial-nerve-block-for-breast-surgery-in-a-pregnant-woman-a-case-report
#6
Boohwi Hong, Seok-Hwa Yoon, Ann Misun Youn, Bum June Kim, Seunghyun Song, Yeomyung Yoon
Regional anesthesia for non-obstetric surgery in parturients is a method to decrease patient and fetal risk during general anesthesia. Thoracic interfascial nerve block can be used as an analgesic technique for surgical procedures of the thorax. The Pecs II block is an interfascial block that targets not only the medial and lateral pectoral nerves, but also the lateral cutaneous branch of the intercostal nerve. Pecto-intercostal fascial block (PIFB) targets the anterior cutaneous branch of the intercostal nerve...
April 2017: Korean Journal of Anesthesiology
https://www.readbyqxmd.com/read/28184271/surgical-excision-of-the-breast-giant-fibroadenoma-under-regional-anesthesia-by-pecs-ii-and-internal-intercostal-plane-block-a-case-report-and-brief-technical-description-a-case-report
#7
Hyungtae Kim, Junho Shim, Ikthae Kim
A 22-years-old female patient at 171 cm and 67 kg visited the Department of Breast Surgery of the hospital with a mass accompanied with pain on the left side breast as chief complaints. Since physical examination revealed a suspected huge mass, breast surgeon decided to perform surgical excision and requested anesthesia to our department. Surgery of breast tumor is often under local anesthesia. However, in case of big size tumor, surgery is usually performed under general anesthesia. The patient feared general anesthesia...
February 2017: Korean Journal of Anesthesiology
https://www.readbyqxmd.com/read/27851263/1628-pecs-i-ii-blocks-as-rescue-analgesia-in-a-patient-undergoing-port-access-cardiac-surgery
#8
Suraj Yalamuri, Rebecca Klinger, William Bullock, Donald Glower, Jeffrey Gadsden, Brandi Bottiger
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27543533/efficacy-of-pectoral-nerve-block-versus-thoracic-paravertebral-block-for-postoperative-analgesia-after-radical-mastectomy-a-randomized-controlled-trial
#9
S Kulhari, N Bharti, I Bala, S Arora, G Singh
BACKGROUND: Pectoral nerve (PecS) block is a recently introduced technique for providing surgical anaesthesia and postoperative analgesia during breast surgery. The present study was planned to compare the efficacy and safety of ultrasound-guided PecS II block with thoracic paravertebral block (TPVB) for postoperative analgesia after modified radical mastectomy. METHODS: Forty adult female patients undergoing radical mastectomy were randomly allocated into two groups...
September 2016: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/27315180/implementation-of-pecs-i-and-pecs-ii-blocks-as-part-of-opioid-sparing-approach-to-breast-surgery
#10
LETTER
Alexander Amir, Steeve Jolin, Stephane Amberg, Scott Nordstrom
No abstract text is available yet for this article.
July 2016: Regional Anesthesia and Pain Medicine
https://www.readbyqxmd.com/read/27097516/-difference-in-the-spread-of-injectate-between-ultrasound-guided-pectoral-nerve-block-i-and-ii-a-cadaver-study
#11
Masaru Kikuchi, Shunsuke Takaki, Takeshi Nomura, Takahisa Goto
BACKGROUND: Pectoral nerve block (PECS block) is first reported by Blanco et al, and mainly used for analgesia for breast surgery in Japan. However, the spread of PECS block is unclear. METHODS: Ultrasound guided PECS I and II blocks were performed in a cadaver, and the cadaver was dissected for evaluation of the spread of coloring matter. RESULTS: The coloring matter by PECS I block was spread to the axillary region between the major and minor pectoral muscles, while PECS II block remained over the fascia of the serratus muscle from mid-clavicular line to middle axillary line...
March 2016: Masui. the Japanese Journal of Anesthesiology
https://www.readbyqxmd.com/read/25376971/pectoral-nerves-i-and-ii-blocks-in-multimodal-analgesia-for-breast-cancer-surgery-a-randomized-clinical-trial
#12
RANDOMIZED CONTROLLED TRIAL
Ghada Mohammad Nabih Bashandy, Dina Nabil Abbas
BACKGROUND: The pectoral nerves (Pecs) block types I and II are novel techniques to block the pectoral, intercostobrachial, third to sixth intercostals, and the long thoracic nerves. They may provide good analgesia during and after breast surgery. Our study aimed to compare prospectively the quality of analgesia after modified radical mastectomy surgery using general anesthesia and Pecs blocks versus general anesthesia alone. METHODS: One hundred twenty adult female patients scheduled for elective unilateral modified radical mastectomy under general anesthesia were randomly allocated to receive either general anesthesia plus Pecs block (Pecs group, n = 60) or general anesthesia alone (control group, n = 60)...
January 2015: Regional Anesthesia and Pain Medicine
https://www.readbyqxmd.com/read/22939099/ultrasound-description-of-pecs-ii-modified-pecs-i-a-novel-approach-to-breast-surgery
#13
R Blanco, M Fajardo, T Parras Maldonado
OBJECTIVE: The Pecs block (pectoral nerves block) is an easy and reliable superficial block inspired by the infraclavicular block approach and the transversus abdominis plane blocks. Once the pectoralis muscles are located under the clavicle the space between the two muscles is dissected to reach the lateral pectoral and the medial pectoral nerves. The main indications are breast expanders and subpectoral prosthesis where the distension of these muscles is extremely painful. MATERIAL AND METHODS: A second version of the Pecs block is described, called "modified Pecs block" or Pecs block type II...
November 2012: Revista Española de Anestesiología y Reanimación
https://www.readbyqxmd.com/read/22924264/asymmetries-in-numerical-density-of-pyramidal-neurons-in-the-fifth-layer-of-the-human-posterior-parietal-cortex
#14
Natasa Djukić Macut, Slobodan Malobabić, Natalija Stefanović, Predrag Mandić, Tatjana Filipović, Aleksandar Maliković, Milena Saranović
BACKGROUND/AIM: Both superior parietal lobule (SPL) of dorsolateral hemispheric surface and precuneus (PEC) of medial surface are the parts of posterior parietal cortex. The aim of this study was to determine the numerical density (Nv) of pyramidal neurons in the layer V of SPL and PEC and their potential differences. METHODS: From 20 (40 hemispheres) formaline fixed human brains (both sexes; 27- 65 years) tissue blocks from SPL and PEC from the left and right hemisphere were used...
August 2012: Vojnosanitetski Pregled. Military-medical and Pharmaceutical Review
https://www.readbyqxmd.com/read/17381687/transgenic-expression-of-hla-e-single-chain-trimer-protects-porcine-endothelial-cells-against-human-natural-killer-cell-mediated-cytotoxicity
#15
Benjamin G Lilienfeld, Mark D Crew, Pietro Forte, Bettina C Baumann, Jörg D Seebach
BACKGROUND: The susceptibility of porcine endothelial cells (pEC) to human natural killer (NK) cells is related to the failure of human major histocompatibility complex (MHC)-specific killer inhibitory receptors to recognize porcine MHC class I molecules. The aims of this study were (i) to assess the protection of pEC against xenogeneic NK-mediated cytotoxicity afforded by the stable expression of HLA-E single chain trimers (SCT) composed of a canonical HLA-E binding peptide antigen, VMAPRTLIL, the mature human beta2-microglobulin, and the mature HLA-E heavy chain, and (ii) to test whether HLA-E expression on pEC and porcine lymphoblastoid cells affects the adhesion of human NK cells...
March 2007: Xenotransplantation
https://www.readbyqxmd.com/read/16968721/angiotensin-converting-enzyme-inhibition-prevents-development-of-collapsing-focal-segmental-glomerulosclerosis-in-thy-1-1-transgenic-mice
#16
COMPARATIVE STUDY
Bart Smeets, Mark L M Steenbergen, Henry B P M Dijkman, Kiek N Verrijp, Nathalie A J M te Loeke, Jan Aten, Eric J Steenbergen, Jack F M Wetzels
BACKGROUND: Thy-1.1 transgenic mice develop hypercellular focal and segmental glomerulosclerosis (FSGS) lesions that mimic human collapsing FSGS, in 7 days after injection with anti-Thy-1.1 antibodies. These lesions consist of proliferating parietal epithelial cells (PECs). We questioned whether the angiotensin converting enzyme inhibitor (ACE), captopril, could prevent the development of FSGS and if protection is related to the timing of drug administration. METHODS: First, we compared the effect of captopril treatment with angiotensin II-(ANGII) independent antihypertensive therapy (triple therapy)...
November 2006: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/12453539/comparison-of-the-antagonistic-effects-of-different-angiotensin-ii-receptor-blockers-in-human-coronary-arteries
#17
COMPARATIVE STUDY
Emil Pantev, Emelie Stenman, Angelica Wackenfors, Lars Edvinsson, Malin Malmsjö
BACKGROUND: Angiotensin II (Ang II) is a potent vasoconstrictor and a deleterious factor in cardiovascular pathophysiology. Ang II receptor blockers (ARBs) have recently been introduced into clinical practice for treatment of hypertension and congestive heart failure. AIMS: This study was undertaken to evaluate the inhibitory effects of ARBs on vasoconstriction in humans. METHODS: Vasomotor tone was analyzed in endothelium denuded, human coronary artery (HCA) segments...
December 2002: European Journal of Heart Failure
https://www.readbyqxmd.com/read/12359626/pharmacological-characterization-of-sb-710411-cpa-c-d-cys-pal-d-trp-lys-val-cys-cpa-amide-a-novel-peptidic-urotensin-ii-receptor-antagonist
#18
David J Behm, Christopher L Herold, Eliot H Ohlstein, Steven D Knight, Dashyant Dhanak, Stephen A Douglas
1. Human urotensin-II (hU-II), a cyclic undecapeptide, is amongst the most potent mammalian vasoconstrictors identified, suggesting that hU-II and its G-protein-coupled receptor (UT) may regulate cardiovascular homeostasis. Such a hypothesis would benefit greatly from the development of selective UT antagonists. 2. Although the somatostatin (SST) antagonist SB-710411 (Cpa-c[D-Cys-Pal-D-Trp-Lys-Val-Cys]-Cpa-amide) is purported to block U-II-induced contractions in rat isolated aorta, little is known about its specific pharmacological properties...
October 2002: British Journal of Pharmacology
https://www.readbyqxmd.com/read/11819032/effects-of-human-urotensin-ii-in-isolated-vessels-of-various-species-comparison-with-other-vasoactive-agents
#19
COMPARATIVE STUDY
Valeria Camarda, Anna Rizzi, Girolamo Calò, Gabrielle Gendron, Stephan I Perron, Evi Kostenis, Paolo Zamboni, Francesco Mascoli, Domenico Regoli
Urotensin II is a cyclic undecapeptide which activates the GPR14 receptor and exerts potent vasoconstrictor effects in some species of fish and mammals. The present study intended to investigate isolated vessels from various species in an attempt to find sensitive preparations to be used in studies of the human urotensin (hU-II)/GPR14 system. Contractile responses evoked by noradrenaline (NA), angiotensin II (Ang II), endothelin 1 (ET-1) and hU-II were measured in large vessels (aorta and some large arteries and veins) of rats, guinea pigs, rabbits, pigs and humans...
February 2002: Naunyn-Schmiedeberg's Archives of Pharmacology
https://www.readbyqxmd.com/read/11490203/angiotensin-induced-enhancement-of-excitatory-junction-potentials-evoked-by-periarteriolar-nerve-stimulation-and-vasoconstriction-in-rat-mesenteric-arteries-are-both-mediated-by-the-angiotensin-at1-receptor
#20
J Ziogas, K Vessey
The aims of the present study were to determine the angiotensin II (AngII) receptor subtype(s) involved in vasoconstriction and enhancement of sympathetic neurotransmission in rat isolated mesenteric arteries. Vasoconstriction was assessed in mesenteric artery ring preparations suspended under 0.5 g of tension in a myograph. In control arteries, with an intact endothelium, AngII (1 nmol/l-3 micromol/l) caused a concentration-dependent contraction. The pEC(50) for AngII was 7.6 +/- 0.2 and the maximum response of 0...
2001: Pharmacology
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