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https://www.readbyqxmd.com/read/28549320/light-emission-miracle-in-the-sea-and-preeminent-applications-of-bioluminescence-in-recent-new-biotechnology
#1
Sana Sharifian, Ahmad Homaei, Roohullah Hemmati, Khosro Khajeh
Bioluminescence is referred to the light emission by a living organism due to a specific biochemical reaction. This interesting feature of the organisms could highly influences behavioral and ecosystem dynamics. Luminescence, mostly observed in marine species, is generally higher in deep-living genera than in benthic or shallow organisms. However, among creatures living in land, fireflies, beetles, springtails and fungi have shown some bioluminescent activities. Classically, the emission of light is catalyzed by luciferase from a substrate...
May 17, 2017: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/28548940/microbiota-gut-brain-axis-and-the-central-nervous-system
#2
REVIEW
Xiqun Zhu, Yong Han, Jing Du, Renzhong Liu, Ketao Jin, Wei Yi
The gut and brain form the gut-brain axis through bidirectional nervous, endocrine, and immune communications. Changes in one of the organs will affect the other organs. Disorders in the composition and quantity of gut microorganisms can affect both the enteric nervous system and the central nervous system (CNS), thereby indicating the existence of a microbiota-gut-brain axis. Due to the intricate interactions between the gut and the brain, gut symbiotic microorganisms are closely associated with various CNS diseases, such as Parkinson's disease, Alzheimer's disease, schizophrenia, and multiple sclerosis...
May 10, 2017: Oncotarget
https://www.readbyqxmd.com/read/28548617/sporadic-pediatric-meningiomas-a-neuroradiological-and-neuropathological-study-of-15-cases
#3
Kristin Huntoon, Charles P Pluto, Lynne Ruess, Daniel R Boué, Christopher R Pierson, Jerome A Rusin, Jeffrey Leonard
OBJECTIVE Sporadic meningiomas have been classified in many different ways. Radiographically, these lesions can be described as occurring in either typical or atypical locations. The purpose of this study was to determine if there are any histopathological differences between sporadic meningiomas that arise in these varying locations in children. METHODS The neuroimaging, histopathological findings, and clinical records in patients with sporadic pediatric meningiomas not associated with neurofibromatosis Type 2 or prior radiation therapy were retrospectively reviewed...
May 26, 2017: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/28548508/possible-dark-matter-annihilation-signal-in-the-ams-02-antiproton-data
#4
Ming-Yang Cui, Qiang Yuan, Yue-Lin Sming Tsai, Yi-Zhong Fan
Using the latest AMS-02 cosmic-ray antiproton flux data, we search for a potential dark matter annihilation signal. The background parameters about the propagation, source injection, and solar modulation are not assumed a priori but based on the results inferred from the recent B/C ratio and proton data measurements instead. The possible dark matter signal is incorporated into the model self-consistently under a Bayesian framework. Compared with the astrophysical background-only hypothesis, we find that a dark matter signal is favored...
May 12, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28548221/psilocybin-good-trip-or-bad-trip
#5
E M Sellers
Much of the history of pharmacology and therapeutics involves finding new uses for old drugs. The latest rediscovery is that of psychedelic drugs. Since they can cause profound distortions of perception and were once used as part of religious ceremonies, such research may seem unusual at this time.
May 26, 2017: Clinical Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/28547576/thoraco-lumbar-selective-fusion-in-adolescent-idiopathic-scoliosis-with-lenke-c-modifier-curves-clinical-and-radiographic-analysis-at-10-year-follow-up
#6
Laura Scaramuzzo, Fabrizio Giudici, Daniele Bongetta, Eleonora Caboni, Leone Minoia, Antonino Zagra
PURPOSE: To examine the radiological and clinical outcomes of a single-center case series of selective thoracic fusions (STF) in adolescent idiopathic scoliosis with Lenke C modifier curves, with a long-term follow-up. METHODS: We evaluated at 6 months and 10 years different radiological parameters on both thoracic and lumbar districts: coronal curves, sagittal curves, apical vertebral translation (AVT), and apical vertebral rotation (AVR). The clinical outcome was determined using the SRS 22 score...
May 25, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28546907/phosphate-framework-electrode-materials-for-sodium-ion-batteries
#7
REVIEW
Yongjin Fang, Jiexin Zhang, Lifen Xiao, Xinping Ai, Yuliang Cao, Hanxi Yang
Sodium ion batteries (SIBs) have been considered as a promising alternative for the next generation of electric storage systems due to their similar electrochemistry to Li-ion batteries and the low cost of sodium resources. Exploring appropriate electrode materials with decent electrochemical performance is the key issue for development of sodium ion batteries. Due to the high structural stability, facile reaction mechanism and rich structural diversity, phosphate framework materials have attracted increasing attention as promising electrode materials for sodium ion batteries...
May 2017: Advanced Science (Weinheim, Baden-Wurttemberg, Germany)
https://www.readbyqxmd.com/read/28546903/comprehensive-reconstruction-and-evaluation-of-pichia-pastoris-genome-scale-metabolic-model-that-accounts-for-1243-orfs
#8
Rui Ye, Mingzhi Huang, Hongzhong Lu, Jiangchao Qian, Weilu Lin, Ju Chu, Yingping Zhuang, Siliang Zhang
BACKGROUND: Pichia pastoris is one of the most important cell factories for production of industrial enzymes and heterogenous proteins. The genome-scale metabolic model of high quality is crucial for comprehensive understanding of the P. pastoris metabolism. METHODS: In this paper, we upgraded P. pastoris genome-scale metabolic model based on the combination of latest genome annotations and literatures. Then the performance of the new model was evaluated using the Cobra Toolbox v2...
2017: Bioresources and Bioprocessing
https://www.readbyqxmd.com/read/28546591/the-healthcare-system-and-the-provision-of-oral-healthcare-in-european-union-member-states-part-8-italy
#9
M Bindi, C Paganelli, K A Eaton, E Widström
In Italy healthcare is provided for all Italian citizens and residents and it is delivered mainly by public providers, with some private or private-public entities. Italy's public healthcare system - the Servizio Sanitario Nazionale (SSN) - is organised by the Ministry of Health and administered on a devolved regional basis. It is financed by general taxation that provides universal coverage, largely free of charge at the point of service. The central government establishes the basic national health benefits package, which must be uniformly provided throughout the country, through services guaranteed under the NHS provision called LEA - (Livelli Essenziali di Assistenza [Essential Level of Assistance]) and allocates national funds to the regions...
May 26, 2017: British Dental Journal
https://www.readbyqxmd.com/read/28545882/emerging-infectious-diseases-and-blood-safety-modeling-the-transfusion-transmission-risk
#10
REVIEW
Philip Kiely, Manoj Gambhir, Allen C Cheng, Zoe K McQuilten, Clive R Seed, Erica M Wood
While the transfusion-transmission (TT) risk associated with the major transfusion-relevant viruses such as HIV is now very low, during the last 20 years there has been a growing awareness of the threat to blood safety from emerging infectious diseases, a number of which are known to be, or are potentially, transfusion transmissible. Two published models for estimating the transfusion-transmission risk from EIDs, referred to as the Biggerstaff-Petersen model and the European Upfront Risk Assessment Tool (EUFRAT), respectively, have been applied to several EIDs in outbreak situations...
May 15, 2017: Transfusion Medicine Reviews
https://www.readbyqxmd.com/read/28545819/comparative-approaches-to-understanding-thyroid-hormone-regulation-of-neurogenesis
#11
REVIEW
Jean-David Gothié, Barbara Demeneix, Sylvie Remaud
Thyroid hormone (TH) signalling, an evolutionary conserved pathway, is crucial for brain function and cognition throughout life, from early development to ageing. In humans, TH deficiency during pregnancy alters offspring brain development, increasing the risk of cognitive disorders. How TH regulates neurogenesis and subsequent behaviour and cognitive functions remains a major research challenge. Cellular and molecular mechanisms underlying TH signalling on proliferation, survival, determination, migration, differentiation and maturation have been studied in mammalian animal models for over a century...
May 22, 2017: Molecular and Cellular Endocrinology
https://www.readbyqxmd.com/read/28545604/climate-change-impact-on-the-tuul-river-flow-in-a-semiarid-region-in-mongolia
#12
Chinzorig Sukhbaatar, Raja Umer Sajjad, Janchivdorj Lunten, Seung-Hoon Yu, Chang-Hee Lee
  This study investigated the impact of climate change on the Tuul River flow in a semiarid region in Mongolia using statistical methods and the Soil and Water Assessment Tool (SWAT). The authors found that the precipitation showed cyclic variability (three dry and two wet periods) at inter- and multi-decadal scales throughout the study period (1945-2012). Both river flow and actual evapotranspiration (ET) showed a positive relationship with precipitation. In addition, the river flow further decreased due to increased water loss in percentage via actual ET even though the amount of actual ET decreased during dry periods...
June 1, 2017: Water Environment Research: a Research Publication of the Water Environment Federation
https://www.readbyqxmd.com/read/28545514/a-coordinated-pcp-cardiologist-telemedicine-model-pctm-in-china-s-community-hypertension-care-study-protocol-for-a-randomized-controlled-trial
#13
Lei Xu, Wei-Yi Fang, Fu Zhu, Hong-Guang Zhang, Kai Liu
BACKGROUND: Hypertension is a major risk factor for cardiovascular disease, and its control rate has remained low worldwide. Studies have found that telemonitoring blood pressure (BP) helped control hypertension in randomized controlled trials. However, little is known about its effect in a structured primary care model in which primary care physicians (PCPs) are partnering with cardiology specialists in electronic healthcare data sharing and medical interventions. This study aims to identify the effects of a coordinated PCP-cardiologist model that applies telemedicine tools to facilitate community hypertension control in China...
May 25, 2017: Trials
https://www.readbyqxmd.com/read/28545182/breast-cancer-in-australian-indigenous-women-incidence-mortality-and-risk-factors
#14
Kriscia A Tapia, Gail Garvey, Mark Mc Entee, Mary Rickard, Patrick Brennan
The Indigenous people of Australia face significant health gaps compared with the general population, with lower life expectancies, higher rates of death, and chronic illness occurring more often than in non-indigenous Australians. Cancer is the second largest contributor to the burden of disease with breast cancer being the most common invasive cancer diagnosed for females. Despite a lower breast cancer incidence compared with non-indigenous women, fatalities occur at an elevated rate and breast cancers have an earlier age of onset...
April 1, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28544731/taking-control-over-microbial-populations-current-approaches-for-exploiting-biological-noise-in-bioprocesses
#15
REVIEW
Frank Delvigne, Jonathan Baert, Hosni Sassi, Patrick Fickers, Alexander Grünberger, Christian Dusny
Phenotypic plasticity of microbial cells has attracted much attention and several research efforts have been dedicated to the description of methods aiming at characterizing phenotypic heterogeneity and its impact on microbial populations. However, different approaches have also been suggested in order to take benefit from noise in a bioprocess perspective, e.g. by increasing the robustness or productivity of a microbial population. This review is dedicated to outline these controlling methods. A common issue, that has still to be addressed, is the experimental identification and the mathematical expression of noise...
May 24, 2017: Biotechnology Journal
https://www.readbyqxmd.com/read/28544319/selected-copper-based-reactions-for-c-n-c-o-c-s-and-c-c-bond-formation
#16
Dawei Ma, Subhajit Bhunia, Govind Goroba Pawar, S Vijay Kumar, Yongwen Jiang
The metal catalyzed cross-coupling reactions are one of the most important transformations in organic synthesis. Copper catalysis has received great attention due to its low toxicity and inexpensive nature. However, traditional Ullmann-type coupling reactions suffered from limited substrate scope and harsh reaction conditions. The introduction of some bidentate ligands such as amino acids, diamines, 1,3-diketones and oxalic diamides during the past two decades has totally changed its scenario, allowing the coupling reactions of aryl halides and nucleophiles to take place at both low reaction temperatures and catalytic loadings...
May 22, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28543986/a-case-of-primordial-odontogenic-tumor-a-new-entity-in-the-latest-who-classification-2017
#17
Toshinori Ando, Madhu Shrestha, Takashi Nakamoto, Kaori Uchisako, Sachiko Yamasaki, Koichi Koizumi, Ikuko Ogawa, Mutsumi Miyauchi, Takashi Takata
Primordial odontogenic tumor (POT) is a rare lesion in the jaw which has been included as a new entity of benign mixed epithelial and mesenchymal odontogenic tumour in the latest World Health Organization (WHO) classification (2017). Only seven cases have been reported. It typically occurs in the posterior mandible. We report an additional case of POT in the maxilla of an 8-year-old girl presenting with an asymptomatic buccal enlargement. A well-defined, unilocular, radiolucent lesion was observed radiographically...
May 25, 2017: Pathology International
https://www.readbyqxmd.com/read/28543134/-real-life-longevity-of-implantable-cardioverter-defibrillator-devices
#18
Antonis S Manolis, Themistoklis Maounis, Spyridon Koulouris, Vassilios Vassilikos
BACKGROUND: Manufacturers of implantable cardioverter-defibrillators (ICDs) promise a 5- to 9-year projected longevity; however, real-life data indicate otherwise. The aim of the present study was to assess ICD longevity among 685 consecutive patients over the last 20 years. HYPOTHESIS: Real-life longevity of ICDs may differ from that stated by the manufacturers. METHODS: The study included 601 men and 84 women (mean age, 63.1 ± 13.3 years)...
May 22, 2017: Clinical Cardiology
https://www.readbyqxmd.com/read/28542291/the-first-darter-aves-anhingidae-fossils-from-india-late-pliocene
#19
Thomas Stidham, Rajeev Patnaik, Kewal Krishan, Bahadur Singh, Abhik Ghosh, Ankita Singla, Simran S Kotla
New fossils from the latest Pliocene portion of the Tatrot Formation exposed in the Siwalik Hills of northern India represent the first fossil record of a darter (Anhingidae) from India. The darter fossils possibly represent a new species, but the limited information on the fossil record of this group restricts their taxonomic allocation. The Pliocene darter has a deep pit on the distal face of metatarsal trochlea IV not reported in other anhingids, it has an open groove for the m. flexor perforatus et perforans digiti II tendon on the hypotarsus unlike New World anhingid taxa, and these darter specimens are the youngest of the handful of Neogene records of the group from Asia...
2017: PloS One
https://www.readbyqxmd.com/read/28541957/the-cutting-edge-of-retinopathy-of-prematurity-care-expanding-the-boundaries-of-diagnosis-and-treatment
#20
Yoshihiro Yonekawa, Benjamin J Thomas, Aristomenis Thanos, Bozho Todorich, Kimberly A Drenser, Michael T Trese, Antonio Capone
PURPOSE: To discuss the latest advances and controversies in the diagnosis and care of infants with retinopathy of prematurity (ROP). METHODS: Literature review. RESULTS: Retinopathy of prematurity remains a major global issue. Industrialized nations now treat profoundly premature infants with posterior and aggressive disease, and middle-income nations are experiencing ROP epidemics. Remote digital imaging may address the decreasing ratio of ROP providers to premature infants, in addition to improving patient care...
May 24, 2017: Retina
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