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https://www.readbyqxmd.com/read/29339647/proceedings-of-the-11th-congress-of-the-international-society-of-nutrigenetics-and-nutrigenomics-isnn-2017
#1
William T Barrington, Anna C Salvador, Jaana A Hartiala, Raffaele De Caterina, Martin Kohlmeier, J Alfredo Martinez, Carin B Kreutzer, David Heber, Aldons J Lusis, Zhaoping Li, Hooman Allayee
The International Society of Nutrigenetics and Nutrigenomics (ISNN) held its 11th annual Congress in Los Angeles, California, between September 16 and 19, 2017. In addition to 2 keynote lectures, 4 plenary sessions included presentations by internationally renowned speakers on cutting-edge areas of research and new discoveries in genetics/genomics, the microbiome, and nutrition. Scientific topics included multi-omics approaches; diet and the microbiome; cancer, longevity, and metabolism; moving the field forward; and translational/educational aspects and the future of medicine...
January 17, 2018: Journal of Nutrigenetics and Nutrigenomics
https://www.readbyqxmd.com/read/29331538/differential-lipid-metabolism-outcomes-associated-with-adrb2-gene-polymorphisms-in-response-to-two-dietary-interventions-in-overweight-obese-subjects
#2
O Ramos-Lopez, J I Riezu-Boj, F I Milagro, L Goni, M Cuervo, J A Martinez
BACKGROUND AND AIMS: A precise nutrigenetic management of hypercholesterolemia involves the understanding of the interactions between the individual's genotype and dietary intake. The aim of this study was to analyze the response to two dietary energy-restricted interventions on cholesterol changes in carriers of two ADRB2 polymorphisms. METHODS AND RESULTS: A 4-month nutritional intervention was conducted involving two different hypo-energetic diets based on low-fat (LF) and moderately high-protein (MHP) dietary patterns...
December 5, 2017: Nutrition, Metabolism, and Cardiovascular Diseases: NMCD
https://www.readbyqxmd.com/read/29325775/nutrigenetic-variants-and-cardio-metabolic-risk-in-women-with-or-without-gestational-diabetes
#3
Marica Franzago, Federica Fraticelli, Daniela Marchetti, Claudio Celentano, Marco Liberati, Liborio Stuppia, Ester Vitacolonna
AIM: Gestational diabetes mellitus (GDM) is the most frequent metabolic disorder in pregnancy and it can be considered a silent risk associated to T2DM and CVD later in life. The aim of this study was to investigate the association of clinical parameters with nine single nucleotide polymorphisms (SNPs) involved with nutrients and metabolism in women with or without GDM in order to identify potential routine clinical markers for early prevention. METHODS: Nine gene variants associated with nutrients and metabolism, namely PPARG2 rs1801282 (C>G); PPARGC1A rs8192678 (C>T); TCF7L2 rs7903146 (C>T); LDLR rs2228671 (C>T); MTHFR rs1801133 (C>T); APOA5 rs662799 (T>C); GCKR rs1260326 (C>T); FTO rs9939609 (T>A); MC4R rs17782313 (T>C) were genotyped in 104 GDM cases and 124 controls using High Resolution Melting (HRM) analysis...
January 8, 2018: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/29234452/genetic-variations-of-cholesteryl-ester-transfer-protein-and-diet-interactions-in-relation-to-lipid-profiles-and-coronary-heart-disease-a-systematic-review
#4
REVIEW
Parvin Mirmiran, Zohre Esfandiar, Firoozeh Hosseini-Esfahani, Gelareh Koochakpoor, Maryam S Daneshpour, Bahar Sedaghati-Khayat, Fereidoun Azizi
Data on diet-genotype interactions in the prevention or treatment of dyslipidemia have increased remarkably. This systematic review aimed to assess nutrigenetic studies regarding the modulating effect of diet on cholesteryl ester transfer protein (CETP) polymorphisms in relation to metabolic traits. Data were collected through studies published between 2000 and SEP. 2016 using five electronic databases. The quality of eligible studies was assessed using a 12-item quality checklist, derived from the STrengthening the REporting of Genetic Association Studies (STREGA) statement...
2017: Nutrition & Metabolism
https://www.readbyqxmd.com/read/29193419/effects-of-artichoke-leaf-extract-supplementation-on-metabolic-parameters-in-women-with-metabolic-syndrome-influence-of-tcf7l2-rs7903146-and-fto-rs9939609-polymorphisms
#5
Khatereh Rezazadeh, Mohammad Rahmati-Yamchi, Leila Mohammadnejad, Mehrangiz Ebrahimi-Mameghani, Abbas Delazar
The metabolic syndrome (MetS) is a multicomponent condition with a complex etiology involving genetic and environmental factors. Artichoke leaf extract (ALE) has shown favorable effects on lipid and glucose metabolism. The present study aimed to investigate the effects of ALE supplementation on metabolic parameters in women with MetS, using a nutrigenetics approach. In this double-blind randomized clinical trial, 50 women (aged 20-50 years) with MetS were randomly allocated into the two groups: "ALE group" (received 1,800 mg hydroalcoholic extract of artichoke as four tablets per day) and "placebo group" (received placebo consisted of corn starch, lactose, and avicel as four tablets per day) for 12 weeks...
November 29, 2017: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/29062169/nutrigenomics-and-nutrigenetics-new-insight-in-disease-prevention-and-cure
#6
EDITORIAL
Praveen Sharma, Shailendra Dwivedi
No abstract text is available yet for this article.
October 2017: Indian Journal of Clinical Biochemistry: IJCB
https://www.readbyqxmd.com/read/29019927/mediterranean-diet-adherence-and-genetic-background-roles-within-a-web-based-nutritional-intervention-the-food4me-study
#7
Rodrigo San-Cristobal, Santiago Navas-Carretero, Katherine M Livingstone, Carlos Celis-Morales, Anna L Macready, Rosalind Fallaize, Clare B O'Donovan, Christina P Lambrinou, George Moschonis, Cyril F M Marsaux, Yannis Manios, Miroslaw Jarosz, Hannelore Daniel, Eileen R Gibney, Lorraine Brennan, Christian A Drevon, Thomas E Gundersen, Mike Gibney, Wim H M Saris, Julie A Lovegrove, Keith Grimaldi, Laurence D Parnell, Jildau Bouwman, Ben Van Ommen, John C Mathers, J Alfredo Martinez
Mediterranean Diet (MedDiet) adherence has been proven to produce numerous health benefits. In addition, nutrigenetic studies have explained some individual variations in the response to specific dietary patterns. The present research aimed to explore associations and potential interactions between MedDiet adherence and genetic background throughout the Food4Me web-based nutritional intervention. Dietary, anthropometrical and biochemical data from volunteers of the Food4Me study were collected at baseline and after 6 months...
October 11, 2017: Nutrients
https://www.readbyqxmd.com/read/28916932/informatics-for-nutritional-genetics-and-genomics
#8
Yuan Gao, Jiajia Chen
While traditional nutrition science is focusing on nourishing population, modern nutrition is aiming at benefiting individual people. The goal of modern nutritional research is to promote health, prevent diseases, and improve performance. With the development of modern technologies like bioinformatics, metabolomics, and molecular genetics, this goal is becoming more attainable. In this chapter, we will discuss the new concepts and technologies especially in informatics and molecular genetics and genomics, and how they have been implemented to change the nutrition science and lead to the emergence of new branches like nutrigenomics, nutrigenetics, and nutritional metabolomics...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/28878180/bariatric-surgery-and-precision-nutrition
#9
REVIEW
Carolina F Nicoletti, Cristiana Cortes-Oliveira, Marcela A S Pinhel, Carla B Nonino
This review provides a literature overview of new findings relating nutritional genomics and bariatric surgery. It also describes the importance of nutritional genomics concepts in personalized bariatric management. It includes a discussion of the potential role bariatric surgery plays in altering the three pillars of nutritional genomics: nutrigenetics, nutrigenomics, and epigenetics. We present studies that show the effect of each patient's genetic and epigenetic variables on the response to surgical weight loss treatment...
September 6, 2017: Nutrients
https://www.readbyqxmd.com/read/28877523/11th-congress-of-the-international-society-of-nutrigenetics-nutrigenomics-isnn-abstracts
#10
(no author information available yet)
No abstract text is available yet for this article.
September 7, 2017: Journal of Nutrigenetics and Nutrigenomics
https://www.readbyqxmd.com/read/28835639/dietary-fat-intake-modulates-effects-of-a-frequent-ace-gene-variant-on-glucose-tolerance-with-association-to-type-2-diabetes
#11
Rita Schüler, Martin A Osterhoff, Turid Frahnow, Matthias Möhlig, Joachim Spranger, Darko Stefanovski, Richard N Bergman, Li Xu, Anne-Cathrin Seltmann, Stefan Kabisch, Silke Hornemann, Michael Kruse, Andreas F H Pfeiffer
The frequent ACE insertion/deletion polymorphism (I/D) is, albeit inconsistently, associated with impaired glucose tolerance and insulin resistance. We recently observed an enhanced upregulation of ACE by elevated fat intake in GG-carriers of the I/D-surrogate rs4343 variant and therefore investigated its potential nutrigenetic role in glucose metabolism. In this nutritional intervention study 46 healthy and non-obese twin pairs consumed recommended low fat diets for 6 weeks before they received a 6-week high fat (HF) diet under isocaloric conditions...
August 23, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28831952/genomics-of-lactation-role-of-nutrigenomics-and-nutrigenetics-in-the-fatty-acid-composition-of-human-milk
#12
REVIEW
Elizabeth Sosa-Castillo, Maricela Rodríguez-Cruz, Carolina Moltó-Puigmartí
Human milk covers the infant's nutrient requirements during the first 6 months of life. The composition of human milk progressively changes during lactation and it is influenced by maternal nutritional factors. Nowadays, it is well known that nutrients have the ability to interact with genes and modulate molecular mechanisms impacting physiological functions. This has led to a growing interest among researchers in exploring nutrition at a molecular level and to the development of two fields of study: nutrigenomics, which evaluates the influence of nutrients on gene expression, and nutrigenetics, which evaluates the heterogeneous individual response to nutrients due to genetic variation...
August 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/28777294/common-genetic-variants-alter-metabolism-and-influence-dietary-choline-requirements
#13
REVIEW
Ariel B Ganz, Kevin C Klatt, Marie A Caudill
Nutrient needs, including those of the essential nutrient choline, are a population wide distribution. Adequate Intake (AI) recommendations for dietary choline (put forth by the National Academies of Medicine to aid individuals and groups in dietary assessment and planning) are grouped to account for the recognized unique needs associated with age, biological sex, and reproductive status (i.e., pregnancy or lactation). Established and emerging evidence supports the notion that common genetic variants are additional factors that substantially influence nutrient requirements...
August 4, 2017: Nutrients
https://www.readbyqxmd.com/read/28761824/the-effect-of-dried-glycyrrhiza-glabra-l-extract-on-obesity-management-with-regard-to-ppar-%C3%AE-2-pro12ala-gene-polymorphism-in-obese-subjects-following-an-energy-restricted-diet
#14
Nazli Namazi, Mohammad Alizadeh, Elham Mirtaheri, Safar Farajnia
Purpose: Obesity is a multi-factorial health problem which results from the interaction of environmental and genetic factors. The aim of the present study was to determine the effects of dried licorice extract with a calorie restricted diet on anthropometric indices and insulin resistance with nutrigenetic approach. Methods: For this pilot, double-blind, placebo-controlled randomized clinical trial, 72 eligible subjects were randomly allocated to Licorice or placebo group. They received a low-calorie diet either with a 1...
June 2017: Advanced Pharmaceutical Bulletin
https://www.readbyqxmd.com/read/28695325/a-modified-response-of-nafld-patients-with-non-significant-fibrosis-in-nutritional-counseling-according-to-gckr-rs1260326
#15
Andriana C Kaliora, Ioanna Panagiota Kalafati, Aristea Gioxari, Anastasia Diolintzi, Alexandros Kokkinos, George V Dedoussis
AIM: To investigate the association between GCKR gene and nutritional treatment in NAFLD-related biomarkers. METHODS: This was an open-label and single-arm clinical trial in 44 overweight or obese adults with NAFLD receiving nutritional counseling for 6 months. Nutritional data, MedDietScore, clinical, biochemical, inflammatory and oxidative stress biomarkers were evaluated before and after intervention. Further, we genotyped GCKR rs1260326 and in T-allele carriers and non-Τ-carriers we assessed associations between the GCKR variant and nutritional counseling related to change in all biomarkers evaluated...
July 10, 2017: European Journal of Nutrition
https://www.readbyqxmd.com/read/28689206/guide-for-current-nutrigenetic-nutrigenomic-and-nutriepigenetic-approaches-for-precision-nutrition-involving-the-prevention-and-management-of-chronic-diseases-associated-with-obesity
#16
Omar Ramos-Lopez, Fermín I Milagro, Hooman Allayee, Agata Chmurzynska, Myung Sook Choi, Rui Curi, Raffaele De Caterina, Lynnette R Ferguson, Leticia Goni, Jing X Kang, Martin Kohlmeier, Amelia Marti, Luis A Moreno, Louis Pérusse, Chandan Prasad, Lu Qi, Ram Reifen, Jose I Riezu-Boj, Rodrigo San-Cristobal, Jose Luis Santos, J Alfredo Martínez
Chronic diseases, including obesity, are major causes of morbidity and mortality in most countries. The adverse impacts of obesity and associated comorbidities on health remain a major concern due to the lack of effective interventions for prevention and management. Precision nutrition is an emerging therapeutic approach that takes into account an individual's genetic and epigenetic information, as well as age, gender, or particular physiopathological status. Advances in genomic sciences are contributing to a better understanding of the role of genetic variants and epigenetic signatures as well as gene expression patterns in the development of diverse chronic conditions, and how they may modify therapeutic responses...
2017: Journal of Nutrigenetics and Nutrigenomics
https://www.readbyqxmd.com/read/28684688/gene-dairy-food-interactions-and-health-outcomes-a-review-of-nutrigenetic-studies
#17
REVIEW
Kevin B Comerford, Gonca Pasin
Each person differs from the next by an average of over 3 million genetic variations in their DNA. This genetic diversity is responsible for many of the interindividual differences in food preferences, nutritional needs, and dietary responses between humans. The field of nutrigenetics aims to utilize this type of genetic information in order to personalize diets for optimal health. One of the most well-studied genetic variants affecting human dietary patterns and health is the lactase persistence mutation, which enables an individual to digest milk sugar into adulthood...
July 6, 2017: Nutrients
https://www.readbyqxmd.com/read/28678615/the-future-of-nutrition-nutrigenomics-and-nutrigenetics-in-obesity-and-cardiovascular-diseases
#18
Alicia Cristina Peña-Romero, Diana Navas-Carrillo, Francisco Marín, Esteban Orenes-Piñero
Over time, the relationship between diet and health has aroused great interest, since nutrition can prevent and treat several diseases. It has been demonstrated that general recommendations on macronutrients and micronutrients do not affect to every individual in the same way because diet is an important environmental factor that interacts with genes. Thus, there is a growing necessity of improving a personalized nutrition to treat obesity and associated medical conditions, taking into account the interactions between diet, genes and health...
July 5, 2017: Critical Reviews in Food Science and Nutrition
https://www.readbyqxmd.com/read/28574454/gene-diet-interactions-in-type-2-diabetes-the-chicken-and-egg-debate
#19
REVIEW
Ángeles Ortega, Genoveva Berná, Anabel Rojas, Franz Martín, Bernat Soria
Consistent evidence from both experimental and human studies indicates that Type 2 diabetes mellitus (T2DM) is a complex disease resulting from the interaction of genetic, epigenetic, environmental, and lifestyle factors. Nutrients and dietary patterns are important environmental factors to consider in the prevention, development and treatment of this disease. Nutritional genomics focuses on the interaction between bioactive food components and the genome and includes studies of nutrigenetics, nutrigenomics and epigenetic modifications caused by nutrients...
June 2, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28272299/evaluating-changes-in-omega-3-fatty-acid-intake-after-receiving-personal-fads1-genetic-information-a-randomized-nutrigenetic-intervention
#20
RANDOMIZED CONTROLLED TRIAL
Kaitlin Roke, Kathryn Walton, Shannon L Klingel, Amber Harnett, Sanjeena Subedi, Jess Haines, David M Mutch
Nutrigenetics research is anticipated to lay the foundation for personalized dietary recommendations; however, it remains unclear if providing individuals with their personal genetic information changes dietary behaviors. Our objective was to evaluate if providing information for a common variant in the fatty acid desaturase 1 (FADS1) gene changed omega-3 fatty acid (FA) intake and blood levels in young female adults (18-25 years). Participants were randomized into Genetic (intervention) and Non-Genetic (control) groups, with measurements taken at Baseline and Final (12 weeks)...
March 6, 2017: Nutrients
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