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Magdalena Więdłocha, Piotr Marcinowicz, Renata Krupa, Marlena Janoska-Jaździk, Marta Janus, Weronika Dębowska, Anna Mosiołek, Napoleon Waszkiewicz, Agata Szulc
No abstract text is available yet for this article.
April 23, 2017: Progress in Neuro-psychopharmacology & Biological Psychiatry
Magdalena Więdłocha, Piotr Marcinowicz, Dorota Sokalla, Bartłomiej Stańczykiewicz
HCV infection is significantly more prevalent in the population of psychiatric patients, drug addicts and people tending to undertake risky sexual behaviors than in the general population. This article presents a spectrum of psychopathological symptoms and psychological dysfunctions, an outline of current theories on the neuropathology and psychiatric aspects of HCV infection treatment. The unspecific character of the psychopathological symptoms in the HCV infection makes the process of thorough diagnostics and adequate treatment difficult, thus the specific and characteristic features have been emphasized...
January 2017: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
Paweł Latacz, Marian Simka, Paweł Brzegowy, Piotr Janas, Marek Kazibudzki, Piotr Pieniążek, Andrzej Ochała, Tadeusz Popiela, Tomasz Mrowiecki
INTRODUCTION: Although surgical endarterectomy remains the treatment of choice for carotid artery stenosis, stenting plays an important role as an alternative treatment modality, especially in high-risk patients. The actual safety profile associated with stenting procedures is probably better than that reported by randomized controlled trials. AIM: To assess the safety of stent implantations in extracranial arteries supplying the brain, and also to identify risk factors associated with this procedure...
2017: Postępy W Kardiologii Interwencyjnej, Advances in Interventional Cardiology
Radosław Parma, Maciej Dąbrowski, Andrzej Ochała, Adam Witkowski, Dariusz Dudek, Zbigniew Siudak, Jacek Legutko
INTRODUCTION: Few studies have assessed the development of transcatheter aortic valve implantation (TAVI) in Poland since its introduction in 2008, and data on current TAVI activity or practice are missing. AIM: To assess the dynamics of TAVI adoption in Poland and to detect differences among Polish centres in TAVI practice and decision-making. MATERIAL AND METHODS: The Polish Interventional Cardiology TAVI Survey (PICTS) was approved by the Polish Association of Cardiovascular Interventions and presented to all 21 national TAVI centres...
2017: Postępy W Kardiologii Interwencyjnej, Advances in Interventional Cardiology
P A Pękala, B M Henry, A Ochała, P Kopacz, G Tatoń, A Młyniec, J A Walocha, K A Tomaszewski
The Achilles tendon (AT) consists of fibers originating from the soleus muscle (SOL), which lies deep, and the medial (GM) and lateral (GL) heads of the gastrocnemius muscle, which lie superficial. As the fibers descend toward the insertion of the AT, the individual subtendons twist around each other. The aim of this study was to investigate the twisted structure of the AT and its individual subtendons. Specimens of the AT, with preserved calcaneal bone and a fragment of the triceps surae muscle, were obtained from 53 fresh-frozen, male cadavers (n=106 lower limbs)...
January 30, 2017: Scandinavian Journal of Medicine & Science in Sports
Karol Zbroński, Zenon Huczek, Kajetan Grodecki, Janusz Kochman, Piotr Scisło, Maciej Dąbrowski, Adam Witkowski, Zbigniew Chmielak, Wojciech Wojakowski, Radosław Parma, Andrzej Ochała, Michał Lelek, Marek Grygier, Anna Olasińska-Wiśniewska, Aleksander Araszkiewicz, Maciej Lesiak, Dariusz Jagielak, Dariusz Ciećwierz, Radosław Wilimski, Dominika Puchta, Katarzyna Paczwa, Krzysztof Filipiak, Grzegorz Opolski
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
Katarzyna Czerwińska-Jelonkiewicz, Marian Zembala, Maciej Dąbrowski, Adam Witkowski, Andrzej Ochała, Janusz Kochman, Dariusz Dudek, Piotr Kübler, Dariusz Jagielak, Janina Stępińska
BACKGROUND: This observational analysis investigated in-hospital safety and efficacy of periprocedural antithrombotic/antiplatelet therapy used in TAVI patients included into the Polish Nationwide Cardiac Surgical and Cardiology Registry of Transcatheter Aortic Valve Implantation (POL-TAVI). METHODS AND RESULTS: All patients who underwent TAVI in the participating centers between 2013 and 2014 were included. The primary endpoints were: severe bleeding, vascular complications, thromboembolic events, myocardial infarction, 30-days mortality, defined according to Valve Academic Research Consortium scale 2...
January 15, 2017: International Journal of Cardiology
Wojciech Wańha, Damian Kawecki, Tomasz Roleder, Beata Morawiec, Sylwia Gładysz, Adam Kowalówka, Tomasz Jadczyk, Barbara Adamus, Tomasz Pawłowski, Grzegorz Smolka, Maciej Kaźmierski, Andrzej Ochała, Ewa Nowalany-Kozielska, Wojciech Wojakowski
BACKGROUND: Katowice-Zabrze registry provides data that can be used to evaluate clinical outcomes of percutaneous coronary interventions in elderly patients (≥70 y/o) treated with either first- (DES-I) or second-generation (DES-II) drug-eluting stents (DES). METHODS: The registry consisted of data from 1916 patients treated with coronary interventions using either DES-I or DES-II stents. For our study, we defined patients ≥70 years of age as elderly. We evaluated any major adverse cardiac and cerebral events (MACCE) at 12-month follow-up...
November 10, 2016: Aging Clinical and Experimental Research
Monika Rak, Anna Ochałek, Ewa Bielecka, Joanna Latasiewicz, Katarzyna Gawarecka, Jolanta Sroka, Jarosław Czyż, Katarzyna Piwowarczyk, Marek Masnyk, Marek Chmielewski, Tadeusz Chojnacki, Ewa Swiezewska, Zbigniew Madeja
BACKGROUND: One of the major challenges limiting the development of gene therapy is an absence of efficient and safe gene carriers. Among the nonviral gene delivery methods, lipofection is considered as one of the most promising. In the present study, a set of cationic polyprenyl derivatives [trimethylpolyprenylammonium iodides (PTAI)] with different lengths of polyprenyl chains (from 7, 8 and 11 to 15 isoprene units) was suggested as a component of efficient DNA vehicles. METHODS: Optimization studies were conducted for PTAI in combination with co-lipid dioleoylphosphatidylethanolamine on DU145 human prostate cancer cells using: size and zeta potential measurements, confocal microscopy, the fluorescein diacetate/ethidium bromide test, cell counting, time-lapse monitoring of cell movement, gap junctional intercellular coupling analysis, antimicrobial activity assay and a red blood cell hemolysis test...
November 2016: Journal of Gene Medicine
Deon V Canyon, Frederick M Burkle
Outcomes of the World Humanitarian Summit were mixed with some refreshing new directions being endorsed and a lack of systemic reform. The selective agenda and OCHAs lack of success in engaging pre-meeting political participation not only hampered the Summit's ability to deal with global issues and institutional reform, but also alienated it from leading aid agencies and governments. The UN's failure to commit to humanitarian principles and global disarray of the humanitarian system indicates the need for extensive reform or a new global humanitarian body...
August 30, 2016: PLoS Currents
Dariusz Dudek, Tomasz Rakowski, Adam Sukiennik, Michał Hawranek, Artur Dziewierz, Jacek Kubica, Piotr Suwalski, Robert Gil, Wojciech Wojakowski, Andrzej Ochała, Wiesław Mazurek, Krzysztof Żmudka, Mariusz Gąsior
No abstract text is available yet for this article.
2016: Postępy W Kardiologii Interwencyjnej, Advances in Interventional Cardiology
Benedikte Bjerge, Nathan Clark, Peter Fisker, Emmanuel Raju
This paper seeks to examine the extent to which technological advances can enhance inter-organizational information sharing in disaster relief. Our case is the Virtual OSOCC (On-Site Operations Coordination Centre) which is a part of the Global Disaster Alert and Coordination System (GDACS) under the United Nations Office for Coordination of Humanitarian Affairs (UN OCHA). The online platform, which has been developing for more than a decade, provides a unique insight into coordination behaviour among disaster management agencies and individual actors...
2016: PloS One
Waleed Al-Salem, Jennifer R Herricks, Peter J Hotez
BACKGROUND: Visceral leishmaniasis (VL), caused predominantly by Leishmania donovani and transmitted by both Phlebotomus orientalis and Phlebotomus martini, is highly endemic in East Africa where approximately 30 thousands VL cases are reported annually. The largest numbers of cases are found in Sudan - where Phlebotomus orientalis proliferate in Acacia forests especially on Sudan's eastern border with Ethiopia, followed by South Sudan, Ethiopia, Somalia, Kenya and Uganda. Long-standing civil war and unrest is a dominant determinant of VL in East African countries...
2016: Parasites & Vectors
Peiqin Li, Zhimin Cao, Zhou Wu, Xing Wang, Xiuhong Li
In this report, the effects of two oligochitosans, i.e., oligochitosan A (OCHA) and oligochitosan B (OCHB), on control of dry rot of Zanthoxylum bungeanum (Z. bungeanum) caused by Fusarium sambucinum (F. sambucinum) were evaluated. First, both oligochitosans show desirable ability to decrease the infection of F. sambucinum. Second, the oligochitosans strongly inhibit the radial colony and submerged biomass growth of F. sambucinum. Lastly, these oligochitosans are capable of increasing the activities of phenylalanine ammonia lyase (PAL), polyphenoloxidase (PPO) and peroxidase (POD) significantly, as well as enhancing the content of total phenolics in Z...
June 30, 2016: International Journal of Molecular Sciences
Tomasz Roleder, Elżbieta Pociask, Wojciech Wańha, Magdalena Dobrolińska, Paweł Gąsior, Grzegorz Smolka, Wojciech Walkowicz, Tomasz Jadczyk, Tomasz Bochenek, Dariusz Dudek, Andrzej Ochała, Katarzyna Mizia-Stec, Zbigniew Gąsior, Michał Tendera, Ziad A Ali, Wojciech Wojakowski
BACKGROUND: The OCTOPUS registry prospectively evaluates the procedural and long-term outcomes of saphenous vein graft (SVG) PCI. The current study assessed the morphology of de novo lesions and in-stent restenosis (ISR) in patients undergoing PCI of SVG. METHODS AND RESULTS: Optical coherence tomography (OCT) of SVG lesions in consecutive patients presenting with stable CAD and ACS was carried out. Thirty-nine patients (32 de novo and 10 ISR lesions) were included in the registry...
July 25, 2016: Circulation Journal: Official Journal of the Japanese Circulation Society
Grzegorz Smolka, Piotr Pysz, Michał Kozłowski, Marek Jasiński, Radosław Gocoł, Tomasz Roleder, Agnieszka Kargul, Andrzej Ochała, Wojciech Wojakowski
INTRODUCTION: Transcatheter paravalvular leak closure (TPVLC) has become an established treatment option but is mostly performed with off-label use of different non-dedicated occluders. The first one specifically designed for TPVLC is the paravalvular leak device (PLD - Occlutech). AIM: We present initial short-term results of a prospective registry intended to assess the safety and efficacy of TPVLC with PLD. MATERIAL AND METHODS: We screened patients with paravalvular leak (PVL) after surgical valve replacement (SVR)...
2016: Postępy W Kardiologii Interwencyjnej, Advances in Interventional Cardiology
Łukasz Rzeszutko, Zbigniew Siudak, Tomasz Tokarek, Krzysztof Plens, Adrian Włodarczak, Andrzej Lekston, Andrzej Ochała, Robert J Gil, Wojciech Balak, Dariusz Dudek
INTRODUCTION: There are limited data describing bioresorbable vascular scaffold (BVS) implantation in complex lesions. Only short-term clinical outcomes are available for patients with acute coronary syndrome (ACS). AIM: To evaluate 12-month clinical outcome, safety and effectiveness of BVS implantation in complex lesions and in stable angina (SA) or ACS. MATERIAL AND METHODS: Five hundred ninety-one patients with SA/ACS were enrolled between October 2012 and November 2013 in 30 invasive cardiology centres in Poland...
2016: Postępy W Kardiologii Interwencyjnej, Advances in Interventional Cardiology
Mariusz Skowerski, Tomasz Roleder, Katarzyna Bańska-Kisiel, Piotr Pysz, Andrzej Ochała, Wojciech Wojakowski, Zbigniew Gąsior
UNLABELLED: The aim of this single-center study was to asses the long-term clinical data of patients with resistant hypertension who underwent radiofrequency renal denervation (RND). METHODS: Out of 86 patients with resistant-hypertension, 15 pts fulfilled the study criteria for performing RND using Simplicity system by Medtronic. RESULTS: Baseline office systolic BP was 204±32.7 and diastolic BP 107.7±15.1mmHg. Baseline 24h ambulatory systolic BP was 151...
July 15, 2016: International Journal of Cardiology
Damian Kawecki, Beata Morawiec, Janusz Dola, Wojciech Wanha, Grzegorz Smolka, Aleksandra Pluta, Kamil Marcinkiewicz, Andrzej Ochała, Ewa Nowalany-Kozielska, Wojciech Wojakowski
BACKGROUND: There are sparse data on the performance of different types of drug-eluting stents (DES) in acute and real-life setting. OBJECTIVE: The aim of the study was to compare the safety and efficacy of first- versus second-generation DES in patients with acute coronary syndromes (ACS). METHODS: This all-comer registry enrolled consecutive patients diagnosed with ACS and treated with percutaneous coronary intervention with the implantation of first- or second-generation DES in one-year follow-up...
May 2016: Arquivos Brasileiros de Cardiologia
Tomasz Roleder, Mariusz Skowerski, Andrzej Wiecek, Marcin Adamczak, Beata Czerwienska, Wojciech Wanha, Tomasz Jadczyk, Lukasz Partyka, Grzegorz Smolka, Wacław Kuczmik, Andrzej Ochała, Dariusz Dudek, Michał Tendera, Zbigniew Gasior, Wojciech Wojakowski
Optical coherence tomography (OCT) imaging at the time of renal denervation (RDN) showed that procedure might cause spasm, intimal injury or thrombus formation. In the present study, we assessed the healing of renal arteries after RDN using OCT and renal angiography in long-term follow-up. OCT and renal angiography were performed in 12 patients (22 arteries) 18.41 ± 5.83 months after RNS. There were no adverse events or complications during the long-term follow-up. In ten patients (83 %), significant reductions of blood pressure was achieved without a change of the antihypertensive medications...
June 2016: International Journal of Cardiovascular Imaging
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