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https://www.readbyqxmd.com/read/28605302/a-brief-corrective-to-levine-s-2017-ethical-concerns-about-treatment-paradigms-for-gender-dysphoria
#1
Kenneth J Zucker
No abstract text is available yet for this article.
June 12, 2017: Journal of Sex & Marital Therapy
https://www.readbyqxmd.com/read/28603386/quality-of-life-improves-early-after-gender-reassignment-surgery-in-transgender-women
#2
Ebba K Lindqvist, Hannes Sigurjonsson, Caroline Möllermark, Johan Rinder, Filip Farnebo, T Kalle Lundgren
BACKGROUND: Few studies have examined the long-term quality of life (QoL) of individuals with gender dysphoria, or how it is affected by treatment. Our aim was to examine the QoL of transgender women undergoing gender reassignment surgery (GRS). METHODS: We performed a prospective cohort study on 190 patients undergoing male-to-female GRS at Karolinska University Hospital between 2003 and 2015. We used the Swedish version of the Short Form-36 Health Survey (SF-36), which measures QoL across eight domains...
2017: European Journal of Plastic Surgery
https://www.readbyqxmd.com/read/28594603/behavior-problems-and-psychiatric-diagnoses-in-girls-with-gender-identity-disorder-a-follow-up-study
#3
Kelley D Drummond, Susan J Bradley, Michelle Peterson-Badali, Doug P VanderLaan, Kenneth J Zucker
This study evaluated the presence of clinical range behavior problems and psychiatric diagnoses in 25 girls referred for Gender Identity Disorder (GID) in childhood (M age, 8.88 years) at the time of follow-up in adolescence or adulthood (M age, 23.2 years). At follow-up, three (12%) of the girls were judged to have persistent GID based on DSM-IV criteria. With regard to behavior problems at follow-up, 39.1% of the girls had a clinical range score on either the Child Behavior Checklist or Adult Behavior Checklist as rated by their mothers and 33...
June 8, 2017: Journal of Sex & Marital Therapy
https://www.readbyqxmd.com/read/28578758/the-primary-health-care-of-transgender-adults
#4
Stuart Aitken
Gender dysphoria is associated with significant health disparity. Gender services perform specialised activities such as diagnosis, endocrine management and liaison with surgical services. Although providing these specialised transition services appears to be safe and improves well-being, significant health disparity remains. Engaging primary care providers is an important part of any strategy to improve the health care of transgender people. The relationships between gender dysphoria and a range of primary care issues such as mental health, cardiovascular disease and cancer are explored...
June 5, 2017: Sexual Health
https://www.readbyqxmd.com/read/28574859/female-to-male-chest-reconstruction-a-review-of-technique-and-outcomes
#5
Daniel P Donato, Norelle K Walzer, Andy Rivera, Lindsey Wright, Cori A Agarwal
PURPOSE: Female-to-male transgender individuals frequently seek out chest wall masculinization as part of their gender transition and to aid with treating gender dysphoria. Critical evaluation of techniques, complications, and outcomes is important particularly as the surgery becomes more commonly performed. METHODS: A retrospective review was performed of all patients undergoing female-to-male chest wall reconstruction by the senior author from 2008 to 2015. Charts were reviewed to evaluate patient demographics, intraoperative details, and postoperative outcomes...
June 1, 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/28557738/cross-sex-hormones-and-metabolic-parameters-in-adolescents-with-gender-dysphoria
#6
Jason Jarin, Elyse Pine-Twaddell, Gylynthia Trotman, Jaime Stevens, Lee Ann Conard, Eshetu Tefera, Veronica Gomez-Lobo
BACKGROUND AND OBJECTIVES: The Endocrine Society states that adolescents with gender dysphoria may start cross-sex hormones. The goal of this study was to identify patterns in metabolic parameters in transgender adolescents receiving cross-sex hormones. METHODS: Data from adolescents aged 14 to 25 years seen in 1 of 4 clinical sites between 2008 and 2014 were retrospectively analyzed. Subjects were divided into affirmed male (female-to-male) patients taking testosterone and affirmed female (male-to-female) patients taking estrogen...
May 2017: Pediatrics
https://www.readbyqxmd.com/read/28553996/gender-dysphoria-and-the-controversy-over-the-safe-schools-program
#7
Patrick Parkinson
The Safe Schools program has attracted great controversy. On one end of the spectrum, it is defended as an anti-bullying program for young people who identify themselves as gay or lesbian, or have issues concerning their gender identity. On the other end of the spectrum, it is regarded as social engineering. This article seeks to promote a discussion of the way in which gender identity issues are addressed in the Safe Schools program. It is argued that the information in this program to Principals, teachers and young people is inaccurate and misleading...
May 30, 2017: Sexual Health
https://www.readbyqxmd.com/read/28539237/effects-of-sex-steroids-on-the-pattern-of-methylation-and-expression-of-the-promoter-region-of-estrogen-and-androgen-receptors-in-people-with-gender-dysphoria-under-cross-sex-hormone-treatment
#8
Gloria Aranda, Eduardo Fernández-Rebollo, Marta Pradas-Juni, Felicia Alexandra Hanzu, Susana G Kalko, Irene Halperin, Mireia Mora
Cross-sex hormone therapy (CHT) is critical for phenotypical and physiological transition in adults with gender dysphoria (GD). However, the impact of the CHT onto the molecular level/epigenetic regulation has not been comprehensively addressed. We postulate that CHT in GD could drive changes at the androgen receptor (AR), estrogen receptor alpha (ESR1) and estrogen receptor beta (ESR2), affecting their DNA methylation pattern and mRNA expression that may influence in the phenotypical changes associated to CHT...
May 21, 2017: Journal of Steroid Biochemistry and Molecular Biology
https://www.readbyqxmd.com/read/28523232/male-to-female-gender-dysphoria-gender-specific-differences-in-resting-state-networks
#9
Benjamin Clemens, Jessica Junger, Katharina Pauly, Josef Neulen, Christiane Neuschaefer-Rube, Dirk Frölich, Gianluca Mingoia, Birgit Derntl, Ute Habel
INTRODUCTION: Recent research found gender-related differences in resting-state functional connectivity (rs-FC) measured by functional magnetic resonance imaging (fMRI). To the best of our knowledge, there are no studies examining the differences in rs-FC between men, women, and individuals who report a discrepancy between their anatomical sex and their gender identity, i.e. gender dysphoria (GD). METHODS: To address this important issue, we present the first fMRI study systematically investigating the differences in typical resting-state networks (RSNs) and hormonal treatment effects in 26 male-to-female GD individuals (MtFs) compared with 19 men and 20 women...
May 2017: Brain and Behavior
https://www.readbyqxmd.com/read/28508877/an-overview-of-female-to-male-gender-confirming-surgery
#10
REVIEW
Shane D Morrison, Mang L Chen, Curtis N Crane
Gender dysphoria is estimated to occur in approximately 25 million people worldwide, and can have severe psychosocial sequelae. Medical and surgical gender transition can substantially improve quality-of-life outcomes for individuals with gender dysphoria. Individuals seeking to undergo female-to-male (FtM) transition have various surgical options available for gender confirmation, including facial and chest masculinization, body contouring, and genital surgery. The World Professional Association for Transgender Health guidelines should be met before the patient undergoes surgery, to ensure that gender-confirming surgery is appropriate and indicated...
May 16, 2017: Nature Reviews. Urology
https://www.readbyqxmd.com/read/28483073/gender-differences-in-behavioral-and-psychological-symptoms-of-patients-with-alzheimer-s-disease
#11
Jeeye Lee, Kang Joon Lee, Hyun Kim
Behavioral and psychological symptoms of dementia (BPSD) in patients with Alzheimer's disease have a strong correlation with cognitive impairment and impairment in activities of daily living. Although recent studies have reported that gender may play a role in BPSD, this finding was not evident in several other studies. The present study classified patients with Alzheimer's disease into groups with mild and moderate dementia to examine the gender differences in BPSD in each group. We divided a total of 125 patients diagnosed with Alzheimer's disease according to the criteria of the fifth edition of the Diagnostic and Statistic Manual of Mental Disorders (DSM-5) into groups with mild and moderate dementia...
April 2017: Asian Journal of Psychiatry
https://www.readbyqxmd.com/read/28479132/patients-priorities-regarding-female-to-male-gender-affirmation-surgery-of-the-genitalia-a-pilot-study-of-47-patients-in-sweden
#12
Josephine Jacobsson, My Andréasson, Lars Kölby, Anna Elander, Gennaro Selvaggi
INTRODUCTION: No surgical technique is reported to be the best option for gender-affirmation surgery (GAS) of the genitalia in transmen. Although patients' preferences are central when choosing a surgical technique, no studies have evaluated this factor. AIM: To investigate transmen's priorities and preferences regarding GAS of the genitalia. METHODS: From November 2015 to March 2016, 54 transmen with the diagnosis of gender dysphoria who were referred to Sahlgrenska University Hospital for discussion of therapeutic steps (surgery and hormonal treatments) were asked to complete a questionnaire on different attributes achievable with GAS, such as sexual and urinary function and appearance...
June 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/28471328/surgical-satisfaction-quality-of-life-and-their-association-after-gender-affirming-surgery-a-follow-up-study
#13
Tim C van de Grift, Els Elaut, Susanne C Cerwenka, Peggy T Cohen-Kettenis, Baudewijntje P C Kreukels
We assessed the outcomes of gender-affirming surgery (GAS, or sex-reassignment surgery) 4 to 6 years after first clinical contact, and the associations between postoperative (dis)satisfaction and quality of life (QoL). Our multicenter, cross-sectional follow-up study involved persons diagnosed with gender dysphoria (DSM-IV-TR) who applied for medical interventions from 2007 until 2009. Of 546 eligible persons, 201 (37%) responded, of whom 136 had undergone GAS (genital, chest, facial, vocal cord and/or thyroid cartilage surgery)...
May 4, 2017: Journal of Sex & Marital Therapy
https://www.readbyqxmd.com/read/28405831/demographic-characteristics-components-of-sexuality-and-gender-and-minority-stress-and-their-associations-to-excessive-alcohol-cannabis-and-illicit-noncannabis-drug-use-among-a-large-sample-of-transgender-people-in-the-united-states
#14
Cesar A Gonzalez, Joseph D Gallego, Walter O Bockting
The current study examined demographics, sexual orientation, gender characteristics, and gender minority stress and their association to excessive alcohol, cannabis, and illicit (noncannabis) drug use among 1210 transgender adults living in the United States. The authors conducted a secondary analysis of data that included 680 transgender women (M age = 32.63, SD age = 12.29) and 530 transgender men (M age = 26.14, SD age = 7.42). A modified version of the Risk Behavioral Assessment quantified participants' alcohol, cannabis, and illicit drug use in the past 3 months...
April 12, 2017: Journal of Primary Prevention
https://www.readbyqxmd.com/read/28403322/serum-concentrations-of-brain-derived-neurotrophic-factor-in-patients-diagnosed-with-gender-dysphoria-undergoing-sex-reassignment-surgery
#15
Maiko A Schneider, Tahiana Andreazza, Anna Martha V Fontanari, Angelo B Costa, Dhiordan C da Silva, Bianca W de Aguiar, Raffael Massuda, Mariana Pedrini, Clarissa S Gama, Karine Schwarz, Marcia Kauer-Sant'Anna, Maria Ines R Lobato
Introduction: Transsexualism (ICD-10) is a condition characterized by a strong and persistent dissociation with one's assigned gender. Sex reassignment surgery (SRS) and hormone therapy provide a means of allowing transsexual individuals to feel more congruent with their gender and have played a major role in treatment over the past 70 years. Brain-derived neurotrophic factor (BDNF) appears to play a key role in recovery from acute surgical trauma and environmentally mediated vulnerability to psychopathology...
January 2017: Trends in Psychiatry and Psychotherapy
https://www.readbyqxmd.com/read/28402749/mental-health-concerns-and-insurance-denials-among-transgender-adolescents
#16
Leena Nahata, Gwendolyn P Quinn, Nicole M Caltabellotta, Amy C Tishelman
PURPOSE: Transgender youth are at high risk for mental health morbidities. Based on treatment guidelines, puberty blockers and gender-affirming hormone therapy should be considered to alleviate distress due to discordance between an individual's assigned sex and gender identity. The goals of this study were to examine the: (1) prevalence of mental health diagnoses, self-injurious behaviors, and school victimization and (2) rates of insurance coverage for hormone therapy, among a cohort of transgender adolescents at a large pediatric gender program, to understand access to recommended therapy...
June 2017: LGBT Health
https://www.readbyqxmd.com/read/28401669/implementation-of-teaching-on-lgbt-health%C3%A2-care
#17
Anna K Taylor, Hannah Condry, David Cahill
BACKGROUND: Lesbian, gay, bisexual and transgender (LGBT) patients represent an important proportion of the population. Despite the health inequalities and barriers to health care noted within this group, there is little evidence of LGBT-focused education within medicine, dentistry or nursing. We introduced and evaluated the effect of a half-day teaching session focused on LGBT health care, delivered to year-2 students. CONTEXT: Initial informal discussion with year-2 and year-3 students suggested that the awareness of health inequalities other than sexual health was limited, and that students had little awareness of other issues such as gender dysphoria and heterosexism...
April 12, 2017: Clinical Teacher
https://www.readbyqxmd.com/read/28382847/gender-identity-and-the-management-of-the-transgender-patient-a-guide-for-non-specialists
#18
REVIEW
Albert Joseph, Charlotte Cliffe, Miriam Hillyard, Azeem Majeed
In this review, we introduce the topic of transgender medicine, aimed at the non-specialist clinician working in the UK. Appropriate terminology is provided alongside practical advice on how to appropriately care for transgender people. We offer a brief theoretical discussion on transgenderism and consider how it relates to broader understandings of both gender and disease. In respect to epidemiology, while it is difficult to assess the exact size of the transgender population in the UK, population surveys suggest a prevalence of between 0...
April 2017: Journal of the Royal Society of Medicine
https://www.readbyqxmd.com/read/28376506/the-spectrum-of-ovotesticular-disorders-of-sex-development-in-south-africa-a-single-centre-experience
#19
Yasmeen Ganie, Colleen Aldous, Yusentha Balakrishna, Rinus Wiersma
OBJECTIVE: To describe the clinical characteristics, biochemistry, histopathology, and long-term outcomes in subjects with ovotesticular (OT) disorder of sex development (DSD). STUDY DESIGN: This is a retrospective subset analysis of 64 cases of histologically confirmed OT DSD. RESULTS: All subjects were South African; 97% (n = 62) were African and 92% (n = 59) were of Zulu ethnicity. The most common karyotype was 46,XX (88%; n = 56), followed by 46,XY (8%), 46,XY/45,X (3%), and 46,XX/46,XY (1%)...
April 3, 2017: Hormone Research in Pædiatrics
https://www.readbyqxmd.com/read/28357782/psychological-characteristics-of-italian-gender-dysphoric-adolescents-a-case-control-study
#20
A D Fisher, J Ristori, G Castellini, C Sensi, E Cassioli, A Prunas, M Mosconi, R Vitelli, D Dèttore, V Ricca, M Maggi
PURPOSE: Gender dysphoria (GD) is associated with clinically significant distress and impairment in social, scholastic, and other important areas of functioning, especially when early onset is reported. The aim of the present study is to assess the psychopathological features associated with GD in adolescence, comparing a group of gender dysphoric adolescents (GDs) with a group of non-referred adolescents (NRs), in terms of body uneasiness, suicide risk, psychological functioning, and intensity of GD...
March 29, 2017: Journal of Endocrinological Investigation
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