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gender dysphoria

John F Strang, Haley Meagher, Lauren Kenworthy, Annelou L C de Vries, Edgardo Menvielle, Scott Leibowitz, Aron Janssen, Peggy Cohen-Kettenis, Daniel E Shumer, Laura Edwards-Leeper, Richard R Pleak, Norman Spack, Dan H Karasic, Herbert Schreier, Anouk Balleur, Amy Tishelman, Diane Ehrensaft, Leslie Rodnan, Emily S Kuschner, Francie Mandel, Antonia Caretto, Hal C Lewis, Laura G Anthony
Evidence indicates an overrepresentation of youth with co-occurring autism spectrum disorders (ASD) and gender dysphoria (GD). The clinical assessment and treatment of adolescents with this co-occurrence is often complex, related to the developmental aspects of ASD. There are no guidelines for clinical care when ASD and GD co-occur; however, there are clinicians and researchers experienced in this co-occurrence. This study develops initial clinical consensus guidelines for the assessment and care of adolescents with co-occurring ASD and GD, from the best clinical practices of current experts in the field...
October 24, 2016: Journal of Clinical Child and Adolescent Psychology
Giuseppe Loverro, Leonardo Resta, Miriam Dellino, Di Naro Edoardo, Maria Arcangela Cascarano, Matteo Loverro, Salvatore Andrea Mastrolia
OBJECTIVE: Female-to-male transition remains a specific clinical indication for long-term testosterone administration. There is a limited number of studies dealing with the effect of androgen treatment on their female receptive targets (mainly breast and uterus) and the knowledge in this field is scarce and, sometimes, contradictory. MATERIALS AND METHODS: We performed a prospective study including 12 patients aged between 20 years and 32 years, with a diagnosis of gender dysphoria, treated with parenteral testosterone administration before sexual reassignment surgery...
October 2016: Taiwanese Journal of Obstetrics & Gynecology
Ronni Hayon
Transgender and gender-nonconforming individuals experience significant health disparities. They are more likely to use drugs and alcohol, smoke, be diagnosed with HIV infection or other sexually transmitted infections, and experience depression or attempt suicide. Many also experience discrimination within the health care system. Office-level strategies to create a safe and affirming space for gender-expansive patients include posting of a nondiscrimination statement, use of intake forms that ask about current gender identity and birth-assigned sex, provision of gender-neutral restrooms, and staff training in use of appropriate language...
October 2016: FP Essentials
Maria Sumia, Nina Lindberg, Marja Työläjärvi, Riittakerttu Kaltiala-Heino
OBJECTIVES: The aim of our study was to explore whether gender dysphoria in adolescent girls is associated with early pubertal timing. METHODS: We compared menarcheal timing among 52 adolescent girl-to-boy sex reassignment (SR) applicants with that of 644 adolescent girls who participated in an adolescent population mental health survey. RESULTS: Of the population girls, 21% presented with early (≤11 years), 61% with normative (12-13 years) and 19% with late (≥14 years) menarcheal timing; among the SR applicants, 42% presented with early, 46% with normative and 12% with late menarcheal timing (p = 0...
October 3, 2016: European Journal of Contraception & Reproductive Health Care
Behzad S Khorashad, Zahra Aghili, Baudewijntje P C Kreukels, Mehran Hiradfar, Ghasem M Roshan, Mozhgan Afkhamizadeh, Mohammad Reza Abbaszadegan, Nosrat Ghaemi, Behnaz Khazai, Peggy Cohen Kettenis
INTRODUCTION: Few studies exist on the psychosexual outcome of homogeneous groups of individuals with 5α-reductase deficiency type 2 (5α-RD-2) and the relation between gender changes and parental hostile and benevolent sexism, which are two components of ambivalent sexism that assume a stereotypical approach toward women in an overtly negative way or a chivalrous, seemingly positive way. AIM: To report on the psychosexual outcome of individuals with 5α-RD-2 and to investigate its relation to the level of parental sexism in a relatively large sample of Iranians with 5α-RD-2...
September 29, 2016: Journal of Sexual Medicine
Heino F L Meyer-Bahlburg
As a side effect of globalization, the ideological and religious heterogeneity of many local populations is increasing. This trend is particularly noticeable at tertiary-care medical centers serving patients with rare conditions such as somatic intersexuality or gender dysphoria and transgenderism (both with and without somatic intersexuality). This special section is designed to familiarize clinicians and researchers with culture-associated gender bias and stigma that may influence attitudes to individuals with somatic or behavioral gender atypicalities...
September 29, 2016: Archives of Sexual Behavior
Alisa L Rich, Laura M Phipps, Sweta Tiwari, Hemanth Rudraraju, Philip O Dokpesi
An increasing number of children are born with intersex variation (IV; ambiguous genitalia/hermaphrodite, pseudohermaphroditism, etc.). Evidence shows that endocrine-disrupting chemicals (EDCs) in the environment can cause reproductive variation through dysregulation of normal reproductive tissue differentiation, growth, and maturation if the fetus is exposed to EDCs during critical developmental times in utero. Animal studies support fish and reptile embryos exhibited IV and sex reversal when exposed to EDCs...
2016: Environmental Health Insights
Angela Ann Joseph, Bindu Kulshreshtha, Iram Shabir, Eunice Marumudi, Tony Sam George, Rajesh Sagar, Manju Mehta, Ariachery C Ammini
Children with disorders of sex development (DSD) manifest at birth with malformed genitalia or later with atypical pubertal development. Those born with malformed genitalia are often diagnosed at birth. However, in resource-poor countries like India, where not all births are supervised by healthcare workers, some of these children remain undiagnosed until puberty or even later. The aim of this study was to assess the gender issues and psychosocial problems of children with DSD. Participants included 205 children with DSD (103 with 46,XX DSD and 102 with 46,XY DSD)...
September 20, 2016: Archives of Sexual Behavior
Laura K Case, David Brang, Rosalynn Landazuri, Pavitra Viswanathan, Vilayanur S Ramachandran
While most people take identification with their body for granted, conditions such as phantom limb pain, alien hand syndrome, and xenomelia suggest that the feeling of bodily congruence is constructed and susceptible to alteration. Individuals with xenomelia typically experience one of their limbs as over-present and aversive, leading to a desire to amputate the limb. Similarly, many transgender individuals describe their untreated sexed body parts as incongruent and aversive, and many experience phantom body parts of the sex they identify with (Ramachandran, 2008)...
September 19, 2016: Archives of Sexual Behavior
Yael Kufert, Andreas Walther, Elyana Feldman, Barbara J Coffey
No abstract text is available yet for this article.
September 2016: Journal of Child and Adolescent Psychopharmacology
A D Fisher, G Castellini, J Ristori, H Casale, G Giovanardi, N Carone, E Fanni, M Mosconi, G Ciocca, E A Jannini, V Ricca, V Lingiardi, M Maggi
PURPOSE: To date, few studies have addressed attitudes toward transgender individuals. In addition, little is known about health care providers' (HCP) attitudes toward sexual minorities. The aim of the present study is to compare attitudes toward homosexual and transgender individuals between gender dysphoric individuals (GDs), general population controls (C) and HCP. METHODS: A total of 310 subjects were considered, including 122 GDs (63 transwomen and 59 transmen), 53 heterosexual HCP (26 males and 27 females) and 135 C...
September 17, 2016: Journal of Endocrinological Investigation
Julián Rodríguez Almagro, Antonio Hernández Martínez, María Carmen Solano Ruiz, José Siles González
AIMS: To research the quality of life of Spanish women with coeliac disease BACKGROUND: Coeliac women express lower quality of life than male coeliacs. DESIGN: Explanatory sequential approach using mixed methods and with a gender perspective. METHODS: The research was carried out between May and July 2015. In its quantitative stage it aims to determine the health-related quality of life (HRQoL) in a representative sample (n=1097) of Spanish adult women with coeliac disease using a specific questionnaire named CD-QOL...
September 14, 2016: Journal of Clinical Nursing
Britt Colebunders, Sam Brondeel, Salvatore D'Arpa, Piet Hoebeke, Stan Monstrey
INTRODUCTION: As gender dysphoria is becoming increasingly accepted in the general population, the number of patients seeking gender reassignment surgery is increasing. Although not every patient with gender dysphoria requires surgery, medical practitioners taking care of these individuals should be aware of the different surgical options. AIM: To review current gender reassignment surgical techniques and update the clinician. METHODS: A review of the literature was performed focusing on the most recent techniques of gender reassignment surgery...
September 10, 2016: Sexual Medicine Reviews
Melanie Bechard, Doug P VanderLaan, Hayley Wood, Lori Wasserman, Kenneth J Zucker
For adolescents with gender dysphoria, it has become common to be offered hormonal treatment to either delay or suppress pubertal development and/or to masculinize or feminize the body. At the same time, it has been our clinical impression that the psychological vulnerability of at least some of these youth has been overlooked. Fifty consecutive referrals of adolescents with a DSM-IV-TR diagnosis of Gender Identity Disorder (GID) constituted the sample. Information obtained at intake was coded for the presence or absence of 15 psychosocial and psychological vulnerability factors...
September 6, 2016: Journal of Sex & Marital Therapy
Jaclyn M White Hughto, Sari L Reisner
OBJECTIVES: To review evidence from prospective cohort studies of the relationship between hormone therapy and changes in psychological functioning and quality of life in transgender individuals accessing hormone therapy over time. DATA SOURCES: MEDLINE, PsycINFO, and PubMed were searched for relevant studies from inception to November 2014. Reference lists of included studies were hand searched. RESULTS: Three uncontrolled prospective cohort studies, enrolling 247 transgender adults (180 male-to-female [MTF], 67 female-to-male [FTM]) initiating hormone therapy for the treatment of gender identity disorder (prior diagnostic term for gender dysphoria), were identified...
January 2016: Transgend Health
Agnieszka Janicka, Michelle Forcier
Primary care providers are increasingly called upon to care for youth that are gender nonconforming. While these youth have the same health concerns as their cisgender peers, gender nonconforming youth face additional challenges. Traditionally, this has been an underserved and marginalized population at significant risk for multiple negative mental and physical health outcomes. Despite the history of disheartening health outcomes, there is hope in interventions that may serve to ameliorate the risks for transgender youth...
2016: Rhode Island Medical Journal
Nina Callens, Maaike Van Kuyk, Jet H van Kuppenveld, Stenvert L S Drop, Peggy T Cohen-Kettenis, Arianne B Dessens
The magnitude of sex differences in human brain and behavior and the respective contributions of biology versus socialization remain a topic of ongoing study in science. The preponderance of evidence attests to the notion that sexual differentiation processes are at least partially hormonally mediated, with high levels of prenatal androgens facilitating male-typed and inhibiting female-typed behaviors. In individuals with Disorders/Differences of Sex Development (DSD), hormonal profiles or sensitivities have been altered due to genetic influences, presumably affecting gender(ed) activity interests as well as gender identity development in a minority of the affected population...
August 27, 2016: Hormones and Behavior
Maureen D Connolly, Marcus J Zervos, Charles J Barone, Christine C Johnson, Christine L M Joseph
This review provides an update on the growing body of research related to the mental health of transgender youth that has emerged since the 2011 publication of the Institute of Medicine report on the health of lesbian, gay, bisexual, and transgender people. The databases PubMed and Ovid Medline were searched for studies that were published from January 2011 to March 2016 in English. The following search terms were used: transgender, gender nonconforming, gender minority, gender queer, and gender dysphoria. Age limits included the terms youth, child, children, teenager*, and adolescen*...
August 17, 2016: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
Claire M Peterson, Abigail Matthews, Emily Copps-Smith, Lee Ann Conard
Prevalence of suicide attempts, self-injurious behaviors, and associated psychosocial factors were examined in a clinical sample of transgender (TG) adolescents and emerging adults (n = 96). Twenty-seven (30.3%) TG youth reported a history of at least one suicide attempt and 40 (41.8%) reported a history of self-injurious behaviors. There was a higher frequency of suicide attempts in TG youth with a desire for weight change, and more female-to-male youth reported a history of suicide attempts and self-harm behaviors than male-to-female youth...
August 19, 2016: Suicide & Life-threatening Behavior
Rosalia Costa, Marco Colizzi
Cross-sex hormonal treatment represents a main aspect of gender dysphoria health care pathway. However, it is still debated whether this intervention translates into a better mental well-being for the individual and which mechanisms may underlie this association. Although sex reassignment surgery has been the subject of extensive investigation, few studies have specifically focused on hormonal treatment in recent years. Here, we systematically review all studies examining the effect of cross-sex hormonal treatment on mental health and well-being in gender dysphoria...
2016: Neuropsychiatric Disease and Treatment
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