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Hourieh Alkadi, Rajwa Jbeily
Stereochemistry has been occupied a great role in manufacture and development of pharmaceuti-cals. Chiral properties play an important role in the determination of pharmacological actions of the drug. In recent years, there is a considerable interest in chiral separation to isolate and examine both enantiomers. This article provides an overview about the stereochemistry and its role in drugs, and also, offers approved isolation methods for enantiomeric pairs.
March 29, 2017: Infectious Disorders Drug Targets
Yong-Ji Xu, Fei Jing
The title compound, C(12)H(15)ClN(2)O, is a piperazine derivative with the potential for use as a starting material for pharmaceutial and agrochemical applications. The structure is stabilized by C-H⋯O hydrogen bonds, C-H⋯π inter-actions and π-π stacking inter-actions [centroid-centroid distance = is 4.760 (2) Å].
2009: Acta Crystallographica. Section E, Structure Reports Online
A Drygas
No abstract text is available yet for this article.
1996: Archiwum Historii i Filozofii Medycyny
T Hamada
"Genroku-Sekenbanashi-Fubunshu" consists of eleven volumes and was written from 1694 to 1703, in the Edo Period. The original book was kept at the Faculty of Literature, Tokyo University. In 1994, this book was first published as one of the Iwanami-Bunko Series. I studied the tales recorded in this book and found that twenty-seven of them were concerned with medical and pharmaceutial sciences. In these medical and pharmaceutical tales, there were several kinds, relating to such matters as spells to cure or prevent illness, curious sicknesses, episodes regarding the origin of remedies, medicinal plants and crude drugs, medical books, doctors and surgeons, persons who lived long, and so forth...
December 1996: Nihon Ishigaku Zasshi. [Journal of Japanese History of Medicine]
M S Prado, M Steppe, M F Tavares, E R Kedor-Hackman, M I Santoro
A capillary electrophoresis method for the determination of diclofenac sodium in a commercial and simulated tablet formation has been described. The aim of this research was to develop a rapid, simple, efficient, and economical method to determine diclofenac sodium in pharmaceutials. The analysis was carried out in a bare silica capillary (75 pm i.d.) with a total length of 50 cm (28 cm to the detector) with a buffer solution containing 20 mM sodium tetraborate, pH 9.23. The applied voltage was 20 kV. Detection was achieved by ultraviolet absorption at 276 nm...
May 1999: Journal of Capillary Electrophoresis and Microchip Technology
A A Shandra, K V Sudakov, G N Kryzhanovskiĭ
The antiepileptic action of neurotropin (Nippon Zoki Pharmaceutied Co. Ltd., Japan) was investigated in acute experiments on rats, mice and cats. The increasing of latent period of the first seizures which were picrotoxin-induced and enhancing of this type of seizures were observed correspondently in 1-24 hours and 8-9 days after intraventricular neurotropin injection. Intraperitoneal neurotropin injection (0.2-0.5 ml) to mice caused dosage-dependent antiseizure action on the model of generalized picrotoxin-induced seizures...
January 1991: Biulleten' Eksperimental'noĭ Biologii i Meditsiny
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