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Cinzia Chiaramonte, Elettra Vestri, Flavia Tripi, Antonino Giulio Giannone, Marcello Cimador, Ferdinando Cataliotti
BACKGROUND: Female vaginoplasty reconstruction, by choice, is usually performed with adjacent tissue. However in some clinical conditions such as high urogenital confluence sinus, cloacal malformation with extreme vaginal hypoplasia, local tissue may not be available. When vaginal replacement is performed in pediatric patients intestinal segments is preferred to non-operative procedures that require continuative dilations. However mucus production, malignant transformation risk and diversion colitis are important side effects...
June 18, 2018: Journal of Pediatric and Adolescent Gynecology
Vandenberk Bert, Vandael Eline, Robyns Tomas, Vandenberghe Joris, Garweg Christophe, Foulon Veerle, Ector Joris, Willems Rik
BACKGROUND: Incorporation of QTc in clinical decision support systems requires accurate QT-interval correction, also during common ECG abnormalities as ventricular conduction defects (VCD). We compared the performance and predictive value of QT correction formulas to design a patient-specific QT correction algorithm (QTcA). METHODS: The first ECG in adult patients with sinus rhythm (SR), atrial fibrillation (AF) and ventricular pacing (VP) was collected retrospectively...
June 21, 2018: Pacing and Clinical Electrophysiology: PACE
Rita Bettencourt-Silva, Josué Pereira, Sandra Belo, Daniela Magalhães, Joana Queirós, Davide Carvalho
Introduction: The diagnosis of pituitary carcinoma is very rare, requires the evidence of metastatic disease, and has a poor overall survival. Malignant prolactinoma frequently requires dopamine agonist therapy, pituitary surgery, radiotherapy, and even chemotherapy. Case description: A 19-year-old female presented with galactorrhea, primary amenorrhea, and left hemianopsia. Complementary study detected hyperprolactinemia and a pituitary macroadenoma with cavernous sinus invasion and suprasellar growth...
2018: Frontiers in Endocrinology
Gabrielius Jakutis, Vytautas Juknevičius, Juratė Barysienė, Dalia Matačiūnienė, Birutė Petrauskienė, Žaneta Petrulionienė, Aleksandras Laucevičius
Introduction: Rapid eye movement (REM) sleep-related bradyarrhythmia syndrome is characterized by pathological asystoles during the REM sleep phase. It is a rare rhythm disorder, being reported only few times in the literature. Due to non-specific symptoms, REM sleep-related bradyarrhythmia might be often underdiagnosed. Other cardiac diseases associated with pathological sinus arrests must be excluded to establish the correct diagnosis of and appropriate therapy for REM sleep-related bradyarrhythmia...
2018: Acta Medica Lituanica
Mosaad Abdel-Aziz, Mohamed Fawaz, Mohamed Kamel, Ahmed Kamel, Talal Aljeraisi
Oroantral fistula (OAF) is a pathologic communication between the oral cavity and the maxillary sinus. It is usually associated with maxillary sinusitis, where drainage of sinus infection is a mandatory step during closure of the fistula. The flap used for closure of OAF should be tension free, broadly based and well vascularized. The aim of this study was to assess the effectiveness of closure of OAF using buccal fat pad (BFP) flap with concomitant endoscopic middle meatal antrostomy for maxillary sinus drainage...
June 20, 2018: Journal of Craniofacial Surgery
Adem Emre Ilhan, Yusuf Muhammed Durna, Ahmet Mahmut Tekin, Fahrettin Yilmaz, Yetkin Zeki Yilmaz
AIM: To examine the effect of the piezoelectric application used increasingly for osteotomy and correction of nasal dorsum in septorhinoplasty surgeries on early auditory functions. METHODS: Our study was conducted after the decision of 10840098-604.01.01-E.9057 taken from Istanbul Medipol University Clinical Research Local Ethics Committee. This study was designed to be prospective, randomized and controlled. Twenty patients between 18 and 50 years of age that piezoelectric technique was used in the study group and 10 patients in the same age range who underwent nasal surgery (endoscopic sinus surgery, septoplasty, lower concha radiofrequency and nasal valve surgery) for any reason in the control group were included in the study...
June 20, 2018: Journal of Craniofacial Surgery
Jeeun Kang, Emad M Boctor, Shawn Adams, Ewa Kulikowicz, Haichong K Zhang, Raymond C Koehler, Ernest M Graham
We hypothesize that noninvasive photoacoustic imaging can accurately measure cerebral venous oxyhemoglobin saturation (sO2 ) in a neonatal model of hypoxia-ischemia. In neonatal piglets, which have a skull thickness comparable to that of human neonates, we validated the noninvasive photoacoustic measurement of sagittal sinus sO2 against that measured directly by blood sampling. Systemic hypoxia was produced by decreasing inspired oxygen stepwise (i.e., 100, 21, 19, 17, 15, 14, 13, 12, 11, 10%) with or without unilateral or bilateral ligation of the common carotid arteries to enhance hypoxia-ischemia...
June 21, 2018: Journal of Applied Physiology
Nicholas J Wagner, Paul D Hastings, Kenneth H Rubin
Substantial theoretical and empirical literature suggests that the extent to which children's early experiences contribute to the development of aggressive behaviors may depend on the psychophysiological regulatory capacities of the child. This study adds to this literature by examining the relations between mothers' rejecting child-rearing attitudes and children's aggressive behaviors, as well as whether children's parasympathetic regulation, both at rest and in response to anger-inducing films, moderate these links...
June 21, 2018: Developmental Psychobiology
N S Fedorova, A Yu Abrosimov, L K Dzeranova, E A Pigarova, I I Dedov
OBJECTIVE: To present the histological and immunohistochemical characteristics of pituitary lactotroph adenomas (PLAs) resistant to dopamine agonist treatment. SUBJECT AND METHODS: The investigators examined paraffin-embedded blocks and histological sections obtained from 19 patients (13 women, 6 men), whose median age was 29 (19, 38) years, after surgical treatment (adenomectomy) for PLAs resistant to dopamine agonist treatment. Immunohistological examination was performed using antibodies against prolactin (PRL), growth hormone (GH), thyroid-stimulating hormone (TSH), adrenocorticotropic hormone (ACTH), luteinizing hormone (LH), follicle-stimulating hormone (FSH), type 2 dopamine receptors (DR2 ), estrogen receptors-α (ERα), the proliferation marker Ki-67, and the endothelial cell marker CD34...
2018: Arkhiv Patologii
E V Shelesko, A D Kravchuk, D N Kapitanov, N A Chernikova, D N Zinkevich
Nasal liquorrhea is cerebrospinal fluid leakage from cerebrospinal fluid spaces of the cerebral cavity into the nasal cavity or paranasal sinuses due to congenital or acquired abnormalities of the skull base bones and meninges of various etiologies. The severity of liquorrhea varies from hidden manifestations to profuse leakage of cerebrospinal fluid from the nasal cavity. The diagnosis of overt nasal liquorrhea is not problematic, but the diagnosis of latent liquorrhea is a challenge. In this case, the disease leads to potentially fatal complications, such as meningitis (the risk amounts to 10-37%), pneumocephaly, pneumonia, etc...
2018: Zhurnal Voprosy Neĭrokhirurgii Imeni N. N. Burdenko
Christoph H F Hämmerle, Dennis Tarnow
OBJECTIVE: The objective of the present paper was to review factors and conditions that are associated with hard and soft-tissue deficiencies at implant sites. IMPORTANCE: Hard- and soft-tissue deficiencies at dental implants are common clinical findings. They can lead to complications and compromise implant survival and, hence, may require therapeutic interventions. It is, therefore, important to understand the etiology of hard and soft-tissue deficiencies. Based on this understanding, strategies should be developed to correct hard and soft-tissue deficiencies with the aim of improving clinical outcomes of implant therapy...
June 2018: Journal of Periodontology
Sarah Kahle, Jonas G Miller, Jonathan L Helm, Paul D Hastings
Physiological recovery from negative emotions may be important for effective self-regulation, but little is known about recovery processes in children. The current study investigated links between autonomic physiology, anger expressions, and emotion regulation in a sample of eighty-three 3.5-year-olds. Respiratory sinus arrhythmia and pre-ejection period were measured during an anger induction task as parasympathetic and sympathetic indices, respectively. We examined whether preschoolers' anger expressions and emotion regulation behaviors were associated with individual differences in physiology...
June 21, 2018: Developmental Psychobiology
Hua Jin, Zhi-Jun Liu, Chun-Lu Yan, Feng-Lin Liu, Li Chen, Qiu-Ju Zhang, Hou-Qian Xu, Ji-Hong Hu, Rong-Hai Dou, Xin-Yang Wen
OBJECTIVES: Investigate the influence of benazepril and amlodipine on the expression of secretin (PZ) and somatostatin (SS) in spontaneously hypertensive rats (SHR). METHODS: Forty-five SHRs (14 weeks old, male) were randomly assigned into 3 groups ( n =15):SHR group, Benazepril group (which was given benazepril 0.90 mg·kg-1 ·d-1 ) and Amlodipine group (SHRs were given amlodipine 0.45 mg· kg-1 ·d-1 ), taking WistarKyoto(WKY) as normal control ( n =15), meanwhile, rats in SHR group and WKY group were given the same volume of distilled water...
February 8, 2018: Chinese Journal of Applied Physiology
Christoph H F Hämmerle, Dennis Tarnow
OBJECTIVE: The objective of the present paper was to review factors and conditions that are associated with hard and soft-tissue deficiencies at implant sites. IMPORTANCE: Hard- and soft-tissue deficiencies at dental implants are common clinical findings. They can lead to complications and compromise implant survival and, hence, may require therapeutic interventions. It is, therefore, important to understand the etiology of hard and soft-tissue deficiencies. Based on this understanding, strategies should be developed to correct hard and soft-tissue deficiencies with the aim of improving clinical outcomes of implant therapy...
June 2018: Journal of Clinical Periodontology
Neşe Asal, Nuray Bayar Muluk, Mikail Inal, Mehmet Hamdi Şahan, Adil Doğan, Osman Kürşat Arıkan
In the present study, we investigated the relationship between sphenoid sinus, carotid canal, and optic canal on paranasal sinus computed tomography (PNSCT). This study was performed retrospectively. PNSCT images of 300 adult subjects (159 male, 141 female). Sphenoid sinus (pneumatisation, dominancy, septation, inter-sinus septa deviation), anterior clinoid process pneumatisation, Onodi cell, carotid and optic canals (width, dehiscence, classification) were measured. In males, type 3 pneumatised sphenoid sinus (in both sides) and in females type 2 pneumatised sphenoid sinus (right side) and type 3 pneumatised sphenoid sinus (left side) were detected more...
June 21, 2018: Neurosurgical Review
Stefania Paolillo, Piergiuseppe Agostoni, Fabiana De Martino, Francesca Ferrazzano, Fabio Marsico, Paola Gargiulo, Elisabetta Pirozzi, Caterina Marciano, Santo Dellegrottaglie, Pasquale Perrone Filardi
Exercise intolerance is a typical manifestation of patients affected by heart failure with reduced ejection fraction (HFrEF); however, the relationship among functional capacity, mortality, and exercise-induced heart rate response during exercise remains unclear in either sinus rhythm or atrial fibrillation subjects. Heart rate increase during incremental load exercise has a typical pattern in normal subjects, whereas it is commonly compromised in HFrEF patients, mainly due to the imbalance of the autonomic nervous system...
July 2018: Heart Failure Reviews
Kazuhiro Yatera, Yasuo Morimoto, Susumu Ueno, Shingo Noguchi, Takako Kawaguchi, Fumihiro Tanaka, Hideaki Suzuki, Toshiaki Higashi
Hexavalent chromium (Cr(VI)) compounds are recognized as carcinogens in the respiratory tract, giving rise to cancers of the lung, nose and nasal sinuses, especially in certain occupational environments. Inhalation exposure of Cr(VI)-containing particles, dusts and fumes commonly occurs in chromium-related occupational environments, such as chromium production, plating, welding of chromium-containing metals and alloys, electroplating, chromium-containing pigments and paints. Epidemiological surveys of chromium compounds have shown strong associations between exposure to Cr(VI) and mortality due to lung cancer, as well as positive associations with cancers of the nose and nasal cavity...
2018: Journal of UOEH
Fabien Squara, Didier Scarlatti, Philippe Riccini, Gauthier Garret, Pamela Moceri, Emile Ferrari
BACKGROUND: Classical fluoroscopic criteria for the documentation of septal right ventricular (RV) lead positioning have poor accuracy. We sought to evaluate the individualized left anterior oblique (LAO) projection as a novel fluoroscopy criterion. METHODS: Consecutive patients undergoing pacemaker or defibrillator implantation were prospectively included. RV lead positioning was assessed by fluoroscopy using posteroanterior, right anterior oblique 30° to rule out coronary sinus positioning, and LAO 40° in the classical group or individualized LAO in the individualized group...
July 2018: Circulation. Arrhythmia and Electrophysiology
Takashi Kunihara, Olaf Wendler, Kerstin Heinrich, Ryota Nomura, Hans-Joachim Schäfers
BACKGROUND:  The optimal choice of conduit and configuration for coronary artery bypass grafting (CABG) in diabetic patients remains somewhat controversial, even though arterial grafts have been proposed as superior. We attempted to clarify the role of complete arterial revascularization using the left internal thoracic artery (LITA) and the radial artery (RA) alone in "T-Graft" configuration on long-term outcome. METHODS AND RESULTS:  From 1994 to 2001, 104 diabetic patients with triple vessel disease underwent CABG using LITA/RA "T-Grafts" (Group-A)...
June 20, 2018: Thoracic and Cardiovascular Surgeon
D-D-S Cavalcante, A-R Pinto-Quidute, M-R Alves-Martins, A-S Walter-de-Aguiar, A-M-P Lima-Cid, P-G-B Silva, R-F Cavalcante, F-W-G Costa
BACKGROUND: Sheehan's syndrome (SS) is one of the leading causes of hypopituitarism in developing countries. It occurs after postpartum necrosis of the pituitary gland, and it is considered a significant public health problem. This paper, apparently unpublished, aimed to perform an analysis on oral aspects in patients with SS. MATERIAL AND METHODS: A cross-sectional study was performed with 23 women diagnosed with SS at the Division of Endocrinology and Diabetes (Walter Cantídio University Hospital, Fortaleza, Brazil)...
June 20, 2018: Medicina Oral, Patología Oral y Cirugía Bucal
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