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https://www.readbyqxmd.com/read/29346767/functional-principles-of-posterior-septal-inputs-to-the-medial-habenula
#1
Yo Otsu, Salvatore Lecca, Katarzyna Pietrajtis, Charly Vincent Rousseau, Païkan Marcaggi, Guillaume Pierre Dugué, Caroline Mailhes-Hamon, Manuel Mameli, Marco Alberto Diana
The medial habenula (MHb) is an epithalamic hub contributing to expression and extinction of aversive states by bridging forebrain areas and midbrain monoaminergic centers. Although contradictory information exists regarding their synaptic properties, the physiology of the excitatory inputs to the MHb from the posterior septum remains elusive. Here, combining optogenetics-based mapping with ex vivo and in vivo physiology, we examine the synaptic properties of posterior septal afferents to the MHb and how they influence behavior...
January 16, 2018: Cell Reports
https://www.readbyqxmd.com/read/29344379/changes-in-contractile-protein-expression-are-linked-to-ventricular-stiffness-in-infants-with-pulmonary-hypertension-or-right-ventricular-hypertrophy-due-to-congenital-heart-disease
#2
Andrew R Bond, Dominga Iacobazzi, Safa Abdul-Ghani, Mohammed Ghorbel, Kate Heesom, Mariangela Wilson, Christopher Gillett, Sarah J George, Massimo Caputo, Saadeh Suleiman, Robert M R Tulloh
Background: The right ventricle (RV) is not designed to sustain high pressure leading to failure. There are no current medications to help RV contraction, so further information is required on adaption of the RV to such hypertension. Methods: The Right Ventricle in Children (RVENCH) study assessed infants with congenital heart disease undergoing cardiac surgery with hypertensive RV. Clinical and echocardiographic data were recorded, and samples of RV were taken from matched infants, analysed for proteomics and compared between pathologies and with clinical and echocardiographic outcome data...
2018: Open Heart
https://www.readbyqxmd.com/read/29342993/-analysis-of-prognosis-and-associated-risk-factors-in-pediatric-idiopathic-pulmonary-arterial-hypertension
#3
Q Liu, C Zhang, Q Q Li, Y Zhu, D Zhang, W G Zhao, H Gu
Objective: To analyze the prognosis and associated risk factors of pediatric idiopathic pulmonary arterial hypertension. Methods: A total of 119 patients under 18 years of age diagnosed as idiopathic pulmonary arterial hypertension in the Pulmonary Arterial Hypertension Center in Beijing Anzhen Hospital between June 2007 and May 2017 were enrolled in this retrospective study. The clinical informations and follow-up data were collected. The endpoints of follow-up were defined as death or undergoing lung transplantation...
January 2, 2018: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://www.readbyqxmd.com/read/29341322/isthmus-sites-identified-by-ripple-mapping-are-usually-anatomically-stable-a-novel-method-to-guide-atrial-substrate-ablation
#4
Vishal Luther, Norman Qureshi, Phang Boon Lim, Michael Koa-Wing, Shahnaz Jamil-Copley, Fu Siong Ng, Zachary Whinnett, D Wyn Davies, Nicholas S Peters, Prapa Kanagaratnam, Nick Linton
BACKGROUND: Post ablation reentrant ATs depend upon conducting isthmuses bordered by scar. Bipolar voltage maps highlight scar as sites of low voltage, but the voltage amplitude of an electrogram depends upon the myocardial activation sequence. Furthermore, a voltage threshold that defines atrial scar is unknown. We used Ripple Mapping (RM) to test whether these isthmuses were anatomically fixed between different activation vectors and atrial rates. METHODS: We studied post-AF ablation ATs where > 1 rhythm was mapped...
January 17, 2018: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/29340831/noninvasive-quantification-of-left-to-right-shunt-by-phase-contrast-magnetic-resonance-imaging-in-secundum-atrial-septal-defect-the-effects-of-breath-holding-and-comparison-with-invasive-oximetry
#5
Yuzo Yamasaki, Satoshi Kawanami, Takeshi Kamitani, Koji Sagiyama, Ichiro Sakamoto, Ken-Ichi Hiasa, Hidetake Yabuuchi, Michinobu Nagao, Hiroshi Honda
To investigate the effect of breath-holding on left-to-right shunts in patients with a secundum atrial septal defect (ASD). Thirty-five consecutive patients with secundum ASDs underwent right heart catheterization and invasive oximetry. Phase-contrast magnetic resonance imaging (MRI) was performed for the main pulmonary artery and ascending aorta. All measurements were obtained during free breathing (FB) (quiet breathing; no breath-hold), expiratory breath-hold (EBH), and inspiratory breath-hold (IBH). Pulmonary circulation flow (Qp) and systemic circulation flow (Qs) were calculated by multiplying the heart rate by the stroke volume...
January 16, 2018: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/29340729/pulmonary-valve-morphology-in-patients-with-bicuspid-aortic-valves
#6
Wilke M C Koenraadt, Margot M Bartelings, Adriana C Gittenberger-de Groot, Regina Bökenkamp, Marco C DeRuiter, Martin J Schalij, Monique R M Jongbloed
The aortic and pulmonary valve share a common developmental origin from the embryonic arterial trunk. Bicuspid aortic valve is the most common congenital anomaly and can occur isolated as well as in association with other congenital heart disease (CHD). Data on pulmonary valve morphology in these cases are scarce. In this study, we aimed to determine pulmonary valve morphology in hearts with BAV associated with CHD. In 83 post-mortem heart specimens with BAV and associated CHD, pulmonary valve morphology was studied and related to BAV morphology...
January 16, 2018: Pediatric Cardiology
https://www.readbyqxmd.com/read/29340494/niemann-pick-disease-type-b-hrct-assessment-of-pulmonary-involvement
#7
Heloisa Maria Pereira Freitas, Alexandre Dias Mançano, Rosana Souza Rodrigues, Bruno Hochhegger, Pedro Paulo Teixeira E Silva Torres, Dante Escuissato, Cesar Augusto Araujo Neto, Edson Marchiori
OBJECTIVE: To analyze HRCT findings in patients with Niemann-Pick disease (NPD) type B, in order to determine the frequency of HRCT patterns and their distribution in the lung parenchyma, as well as the most common clinical characteristics. METHODS: We studied 13 patients (3 males and 10 females) aged 5 to 56 years. HRCT images were independently evaluated by two observers, and disagreements were resolved by consensus. The inclusion criteria were presence of abnormal HRCT findings and diagnosis of NPD type B confirmed by histopathological examination of a bone marrow, lung, or liver biopsy specimen...
November 2017: Jornal Brasileiro de Pneumologia: Publicaça̋o Oficial da Sociedade Brasileira de Pneumologia e Tisilogia
https://www.readbyqxmd.com/read/29339711/unusual-combination-of-mitral-valve-prolapse-bicuspid-aortic-valve-and-ventricular-septal-defect-restricted-by-the-tricuspid-septal-leaflet
#8
Umut Kocabaş, Esra Kaya, Cahide Soydaş Çınar
No abstract text is available yet for this article.
January 2018: Anatolian Journal of Cardiology
https://www.readbyqxmd.com/read/29338861/extracorporeal-membrane-oxygenation-before-surgical-repair-of-a-postinfarction-ventricular-septal-defect
#9
Hellmuth R Muller Moran, Vikas Dutta, Weiang Yan, Nitin N Ghorpade, Rakesh C Arora, Rohit K Singal, Johann Strumpher
No abstract text is available yet for this article.
December 13, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29337121/the-society-of-thoracic-surgeons-congenital-heart-surgery-database-2018-update-on-outcomes-and-quality
#10
Jeffrey P Jacobs, John E Mayer, Sara K Pasquali, Kevin D Hill, David M Overman, James D St Louis, S Ram Kumar, Carl L Backer, Charles D Fraser, James S Tweddell, Marshall L Jacobs
The Society of Thoracic Surgeons Congenital Heart Surgery Database is a comprehensive clinical outcomes registry which captures almost all pediatric cardiac surgical operations in the United States. It is the platform for all activities of The Society of Thoracic Surgeons related to the analysis of outcomes and the improvement of quality in this subspecialty. This article summarizes current aggregate national outcomes in congenital and pediatric cardiac surgery and reviews related activities in the areas of quality measurement, performance improvement, and transparency...
January 11, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29337012/expanding-the-limits-of-endoscopic-intraorbital-tumor-resection-using-3-dimensional-reconstruction
#11
Luciano Lobato Gregorio, Nicolas Y Busaba, Marcel M Miyake, Suzanne K Freitag, Benjamin S Bleier
INTRODUCTION: Endoscopic orbital surgery is a nascent field and new tools are required to assist with surgical planning and to ascertain the limits of the tumor resectability. OBJECTIVE: We purpose to utilize three-dimensional radiographic reconstruction to define the theoretical lateral limit of endoscopic resectability of primary orbital tumors and to apply these boundary conditions to surgical cases. METHODS: A three-dimensional orbital model was rendered in 4 representative patients presenting with primary orbital tumors using OsiriX open source imaging software...
December 26, 2017: Brazilian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/29336408/pneumopericardium-after-minimally-invasive-atrial-septal-defect-closure
#12
Aditya Lamba, Rahul Dutta, Rajesh K Chand
Minimally invasive atrial septal defect (ASD) closure is a commonly performed cardiac surgical procedure and has good outcome. We report an interesting chest X-ray showing pneumopericardium in a patient who underwent ASD closure using a minimally invasive approach.
January 2018: Annals of Cardiac Anaesthesia
https://www.readbyqxmd.com/read/29336395/tricuspid-valve-straddling-an-uncommon-cause-of-left-ventricular-outflow-tract-obstruction-in-transposition-of-great-artery-with-ventricular-septal-defect
#13
Bhupesh Kumar, Aveek Jayant, Ganesh Kumar Munirathinam, Sachin Mahajan
Transposition of great arteries (TGA) can be associated with left ventricle outflow tract (LVOT) obstruction. In the presence of ventricular septal defect (VSD), septal leaflet of tricuspid valve may prolapse through perimembranous VSD or rarely tricuspid valve tissue may override to produce LVOT obstruction. Occasionally, this may be mistaken for vegetation due to associated pulmonary valve endocarditis. We report a case of d-TGA with presumptive pulmonary valve endocarditis and LVOT obstruction that was found to be due to tricuspid valve straddling on transesophageal echocardiography, resulting in change in the surgical plan and thus avoiding catastrophe...
January 2018: Annals of Cardiac Anaesthesia
https://www.readbyqxmd.com/read/29336382/atrioventricular-septal-defects
#14
EDITORIAL
Sandeep Chauhan
No abstract text is available yet for this article.
January 2018: Annals of Cardiac Anaesthesia
https://www.readbyqxmd.com/read/29335778/hippocampal-area-ca2-properties-and-contribution-to-hippocampal-function
#15
REVIEW
Vincent Robert, Sadiyah Cassim, Vivien Chevaleyre, Rebecca A Piskorowski
This review focuses on area CA2 of the hippocampus, as recent results have revealed the unique properties and surprising role of this region in encoding social, temporal and contextual aspects of memory. Originally identified and described by Lorente de No, in 1934, this region of the hippocampus has unique intra-and extra-hippocampal connectivity, sending and receiving input to septal and hypothalamic regions. Recent in vivo studies have indicated that CA2 pyramidal neurons encode spatial information during immobility and play an important role in the generation of sharp-wave ripples...
January 15, 2018: Cell and Tissue Research
https://www.readbyqxmd.com/read/29334830/cardiopulmonary-bypass-for-a-patient-with-congenital-hyperinsulinemia
#16
Richard Crook, Richard Issitt
Congenital hyperinsulinism is a clinical syndrome of pancreatic β-cell dysfunction characterized by failure to suppress insulin secretion in the presence of hypoglycemia. Here, we describe the concerns, the techniques used to ameliorate these potential problems, and the outcomes for a child with this condition undergoing cardiopulmonary bypass for correction of an atrial septal defect.
January 1, 2018: World Journal for Pediatric & Congenital Heart Surgery
https://www.readbyqxmd.com/read/29333842/an-adolescent-with-idiopathic-pleuroparenchymal-fibroelastosis-case-report
#17
Emine Atag, Nilay Bas Ikizoglu, Yasemin Gokdemir, Ela Erdem Eralp, Gursu Kiyan, Dilek Yilmazbayhan, Bulent Karadag
Idiopathic pleuroparenchymal fibroelastosis (IPPFE) is a rare disorder recently included in rare idiopathic interstitial pneumonias according to the updated American Thoracic Society/European Respiratory Society classification. IPPFE is characterized by pleural and subpleural parenchymal fibrosis causing volume loss predominantly in the upper lung lobes. Age of onset is variable, IPPFE mainly occurs in third and fourth decades. We present a 16 year old patient with a 2-year history of exertional dyspnea, nonproductive cough and weight loss...
February 1, 2018: Archivos Argentinos de Pediatría
https://www.readbyqxmd.com/read/29333794/ablation-induced-change-in-the-course-of-fascicular-tachycardia
#18
Avishag Laish-Farkash, Avi Sabbag, Michael Glikson, Aharon Glick, Vladimir Khalameizer, Amos Katz, Yoav Michowitz
BACKGROUND: Multiform fascicular tachycardia (FT) was recently described as a ventricular tachycardia (VT) that has a reentrant mechanism using multiple fascicular branches and produces alternate fascicular VT forms. Ablating the respective fascicle may cause a change in the reentrant circuit resulting in a change in morphology. Ablation of the septal fascicle is crucial for successful treatment. OBJECTIVES: To describe four cases of FT in which ablation induced a change in QRS morphologies and aggravated clinical course...
January 2018: Israel Medical Association Journal: IMAJ
https://www.readbyqxmd.com/read/29333221/horseshoe-like-shaped-atrial-septal-defects-confirmed-on-three-dimensional-transesophageal-echocardiography
#19
Jin-Sun Park, Joon-Han Shin
No abstract text is available yet for this article.
December 2017: Journal of Cardiovascular Ultrasound
https://www.readbyqxmd.com/read/29332171/long-term-patient-related-outcome-measures-of-septoplasty-a-systematic-review
#20
REVIEW
Chi Lap Nicholas Tsang, Theresa Nguyen, Torunn Sivesind, Anders Cervin
PURPOSE: Septoplasty is a common rhinological procedure intended to relieve symptoms of chronic nasal obstruction. However, there remains a question as to whether patients obtain symptom improvement and are satisfied with surgical outcomes in the months and years after septoplasty. This review aims to evaluate the long-term efficacy of functional septoplasty for nasal septal deviation. METHODS: A systematic review of the literature was conducted from November 2014 to March 2016 using the Cochrane, EMBASE, and PubMed databases...
January 13, 2018: European Archives of Oto-rhino-laryngology
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