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https://www.readbyqxmd.com/read/28550696/the-case-for-quality-improvement
#1
Christina Krause
Healthcare systems around the world are facing increasing public and government scrutiny, financial pressures and challenges from growing complexity. There is a need to accelerate the pace of change, and improve the quality of care while reducing cost. These changes must centre on improving care and increasing accountability for quality in the system. But how do we achieve this goal?
2017: Healthcare Quarterly
https://www.readbyqxmd.com/read/28550692/improving-health-system-efficiency-perspectives-of-decision-makers
#2
Sara Allin, Sara Guilcher, Dana Riley, Yu Janice Zhang
While improving health system efficiency, or value for money, is a priority in Canada, there is little information about optimal approaches for improvement in the Canadian context. Through interviews with senior health system decision-makers from two provinces, this study conducted by the Canadian Institute for Health Information identified the following five main themes along with actions that can be taken to improve health system efficiency in Canada: performance monitoring for accountability and decision-making, system-level integration in governance and care delivery, partnerships outside the health sector to improve population health, physician engagement and remuneration and flexible funding...
2017: Healthcare Quarterly
https://www.readbyqxmd.com/read/28550643/housing-experiences-among-opioid-dependent-criminal-justice-involved-individuals-in-washington-d-c
#3
Alese Wooditch, Mary Mbaba, Marissa Kiss, William Lawson, Faye Taxman, Frederick L Altice
Residential mobility and type of housing contributes to an individual's likelihood and frequency of drug/alcohol use and committing criminal offenses. Little research has focused simultaneously on the influence of housing status on the use of drugs and criminal behavior. The present study examines how residential mobility (transitions in housing) and recent housing stability (prior 30 days) correlates with self-reported criminal activity and drug/alcohol use among a sample of 504 addicted, treatment-seeking opioid users with a history of criminal justice involvement...
May 26, 2017: Journal of Urban Health: Bulletin of the New York Academy of Medicine
https://www.readbyqxmd.com/read/28550297/reef-building-corals-thrive-within-hot-acidified-and-deoxygenated-waters
#4
Emma F Camp, Matthew R Nitschke, Riccardo Rodolfo-Metalpa, Fanny Houlbreque, Stephanie G Gardner, David J Smith, Marco Zampighi, David J Suggett
Coral reefs are deteriorating under climate change as oceans continue to warm and acidify and thermal anomalies grow in frequency and intensity. In vitro experiments are widely used to forecast reef-building coral health into the future, but often fail to account for the complex ecological and biogeochemical interactions that govern reefs. Consequently, observations from coral communities under naturally occurring extremes have become central for improved predictions of future reef form and function. Here, we present a semi-enclosed lagoon system in New Caledonia characterised by diel fluctuations of hot-deoxygenated water coupled with tidally driven persistently low pH, relative to neighbouring reefs...
May 26, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28550289/heat-transfer-enhancement-in-free-convection-flow-of-cnts-maxwell-nanofluids-with-four-different-types-of-molecular-liquids
#5
Sidra Aman, Ilyas Khan, Zulkhibri Ismail, Mohd Zuki Salleh, Qasem M Al-Mdallal
This article investigates heat transfer enhancement in free convection flow of Maxwell nanofluids with carbon nanotubes (CNTs) over a vertically static plate with constant wall temperature. Two kinds of CNTs i.e. single walls carbon nanotubes (SWCNTs) and multiple walls carbon nanotubes (MWCNTs) are suspended in four different types of base liquids (Kerosene oil, Engine oil, water and ethylene glycol). Kerosene oil-based nanofluids are given a special consideration due to their higher thermal conductivities, unique properties and applications...
May 26, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28550281/decadal-variations-in-eastern-canada-s-taiga-wood-biomass-production-forced-by-ocean-atmosphere-interactions
#6
Etienne Boucher, Antoine Nicault, Dominique Arseneault, Yves Bégin, Mehdi Pasha Karami
Across Eastern Canada (EC), taiga forests represent an important carbon reservoir, but the extent to which climate variability affects this ecosystem over decades remains uncertain. Here, we analyze an extensive network of black spruce (Picea mariana Mill.) ring width and wood density measurements and provide new evidence that wood biomass production is influenced by large-scale, internal ocean-atmosphere processes. We show that while black spruce wood biomass production is primarily governed by growing season temperatures, the Atlantic ocean conveys heat from the subtropics and influences the decadal persistence in taiga forests productivity...
May 26, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28550085/knockdown-of-sodium-calcium-exchanger-1-induces-epithelial-to-mesenchymal-transition-in-kidney-epithelial-cells
#7
Sona Lakshme Balasubramaniam, Anilkumar Gopalakrishnapillai, Nicholas J Petrelli, Sonali P Barwe
Mesenchymal to epithelial transition (MET) and epithelial to mesenchymal transition (EMT) are important processes in kidney development. Failure to undergo MET during development leads to the initiation of Wilms tumor (WT) whereas EMT contributes to the development of renal cell carcinomas (RCC). The role of calcium regulators in governing these processes is becoming evident. We demonstrated earlier that Na+/Ca2+ exchanger 1 (NCX1), a major calcium exporter in renal epithelial cells, regulates epithelial cell motility...
May 26, 2017: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/28549969/the-dth8-hd1-module-mediates-day-length-dependent-regulation-of-rice-flowering
#8
Anping Du, Wei Tian, Menghao Wei, Wei Yan, Hang He, Da Zhou, Xi Huang, Shigui Li, Xinhao Ouyang
Photoperiodic flowering is one of the most important pathways to govern flowering in rice (Oryza sativa), in which Heading date 1 (Hd1), an ortholog of the Arabidopsis CONSTANS gene, encodes a pivotal regulator. Hd1 promotes flowering under short-day conditions but represses flowering under long-day conditions by regulating the expression of Heading date 3a (Hd3a), the rice FLOWERING LOCUS T (FT) ortholog. However, the molecular mechanism by which Hd1 reverses its activity in response to day length is largely unknown...
May 23, 2017: Molecular Plant
https://www.readbyqxmd.com/read/28549824/the-hsp90-chaperone-network-modulates-candida-virulence-traits
#9
REVIEW
Teresa R O'Meara, Nicole Robbins, Leah E Cowen
Hsp90 is a conserved molecular chaperone that facilitates the folding and function of client proteins. Hsp90 function is dynamically regulated by interactions with co-chaperones and by post-translational modifications. In the fungal pathogen Candida albicans, Hsp90 enables drug resistance and virulence by stabilizing diverse signal transducers. Here, we review studies that have unveiled regulators of Hsp90 function, as well as downstream effectors that govern the key virulence traits of morphogenesis and drug resistance...
May 23, 2017: Trends in Microbiology
https://www.readbyqxmd.com/read/28549749/shared-decision-making-in-iran-current-and-future-trends
#10
Samira Abbasgholizadeh Rahimi, Mahasti Alizadeh, France Légaré
This paper describes the current situation of shared decision making (SDM) in the Iranian healthcare system, discusses barriers to implementation and gives future directions. What about policy regarding SDM? Although the Ministry of Health and Medical Education has enacted some legislation on informed consent and patients' rights, there is no policy specifically regarding SDM in Iran. What about decision support tools for patients? Although some Iranian researchers and clinicians have highlighted patients' desire to be informed and involved in decisions related to their health, there is no program to develop or evaluate decision support tools such as patient decision aids in Iran...
May 23, 2017: Zeitschrift Für Evidenz, Fortbildung und Qualität Im Gesundheitswesen
https://www.readbyqxmd.com/read/28549619/a-mechanical-model-for-diversified-insect-wing-margin-shapes
#11
Yukitaka Ishimoto, Kaoru Sugimura
The wings in different insect species are morphologically distinct with regards to their size, outer contour (margin) shape, venation, and pigmentation. The basis of the diversity of wing margin shapes remains unknown, despite the fact that gene networks governing the Drosophila wing development have been well characterised. Among the different types of wing margin shapes, smoothly curved contour is the most frequently found and implies the existence of a highly organised, multicellular mechanical structure...
May 23, 2017: Journal of Theoretical Biology
https://www.readbyqxmd.com/read/28549480/improving-the-appropriateness-of-antipsychotic-prescribing-in-nursing-homes-a-mixed-methods-process-evaluation-of-an-academic-detailing-intervention
#12
L Desveaux, M Saragosa, J Rogers, L Bevan, H Loshak, A Moser, S Feldman, L Regier, L Jeffs, N M Ivers
BACKGROUND: In 2014, nursing home administration and government officials were facing increasing public and media scrutiny around the variation of antipsychotic medication (APM) prescribing across Ontario nursing homes. In response, policy makers partnered to test an academic detailing (AD) intervention to address appropriate prescribing of APM in nursing homes in a cluster-randomized trial. This mixed-methods study aimed to explore how and why the AD intervention may have resulted in changes in the nursing home context...
May 26, 2017: Implementation Science: IS
https://www.readbyqxmd.com/read/28549473/attitudes-of-consumers-and-live-poultry-workers-to-central-slaughtering-in-controlling-h7n9-a-cross-sectional-study
#13
Xiao Lin, Dingmei Zhang, Xinwei Wang, Yun Huang, Zhicheng Du, Yaming Zou, Jiahai Lu, Yuantao Hao
BACKGROUND: Guangdong Province in the Pearl River Delta of Southeast China is among the areas in the country with the highest rates of avian flu cases. In order to control the outbreak of human-infected H7N9 cases, Guangdong launched a new policy on the central slaughtering of live poultry in 2015. This study aims to evaluate attitudes of consumers and live-poultry workers toward the policy. The live-poultry workers consisted of two sub-groups: live-poultry traders and poultry farm workers...
May 26, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28549472/understanding-and-addressing-contraceptive-stockouts-to-increase-family-planning-access-and-uptake-in-senegal
#14
Leah Hasselback, Modibo Dicko, Claire Viadro, Soussaba Ndour, Oumy Ndao, Jennifer Wesson
BACKGROUND: Senegal's government has pledged to reduce contraceptive stockouts, which have been frequent in public sector health facilities. An innovative distribution system called the Informed Push Model (IPM) addresses supply chain obstacles through direct regional-to-facility delivery of contraceptives and use of private sector logistics operators. Following promising pilot results, Senegal's Ministry of Health and Social Action committed to a three-year (2013-2016) expansion of IPM to all public health facilities nationwide...
May 26, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28549427/developing-an-australian-first-recovery-model-for-parents-in-victorian-mental-health-and-family-services-a-study-protocol-for-a-randomised-controlled-trial
#15
Darryl Maybery, Melinda Goodyear, Andrea Reupert, Jade Sheen, Warren Cann, Kim Dalziel, Phillip Tchernagovski, Brendan O'Hanlon, Henry von Doussa
BACKGROUND: A considerable number of people with a mental illness are parents caring for dependent children. For those with a mental illness, parenting can provide a sense of competence, belonging, identity and hope and hence is well aligned to the concept of personal recovery. However, little research has focused on the recovery journey of those who are parents and have a mental illness. This randomised controlled trial aims to (i) evaluate the effectiveness of an intervention model of recovery for parents (Let's Talk about Children) in three different mental health service sectors and (ii) examine the economic value of a larger roll out (longer term) of the parent recovery model...
May 26, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28549323/investigation-of-submicron-aerosol-characteristics-in-changzhou-china-composition-source-and-comparison-with-co-collected-pm2-5
#16
Zhaolian Ye, Qing Li, Jiashu Liu, Shipeng Luo, Quanfa Zhou, Chenglu Bi, Shuaishuai Ma, Yanfang Chen, Hui Chen, Ling Li, Xinlei Ge
Mass concentrations and chemical compositions of submicron particles (PM1) collected during July 2015 to April 2016 in Changzhou, a city in the Yangtze River Delta region, were systematically investigated for the first time. Specifically, an Aerodyne soot particle aerosol mass spectrometer (SP-AMS) was employed to characterize the water-soluble organic matter (WSOM). The average concentration of PM1 was 63.6 μg m(-3), occupying ∼60% of co-collected PM2.5 mass. Water soluble inorganic ions (WSIIs) was the most abundant component with secondary ions (SO4(2-), NO3(-) and NH4(+)) as the dominant species...
May 17, 2017: Chemosphere
https://www.readbyqxmd.com/read/28549120/dementia-capable-care-coordination-in-duals-demonstration-programs-workforce-needs-promising-practices-and-policy
#17
Brooke Hollister, Jason D Flatt, Susan A Chapman
Background and Objectives: This study describes the program requirements, workforce competencies, and barriers for dementia capable care coordination within health plans from seven states participating in the Center for Medicare and Medicaid Services demonstration programs for dually-eligible Medicare and Medicaid beneficiaries. Research Design and Methods: Data came from contracts, policy documents, and 24 semistructured key informant interviews with national experts and leaders from community-based organizations, advocacy organizations, researchers, federal and state government, and health plans in the seven states...
May 25, 2017: Gerontologist
https://www.readbyqxmd.com/read/28548819/tuning-the-properties-of-polymer-capsules-for-cellular-interactions
#18
Huanli Sun, Jiwei Cui, Yi Ju, Xi Chen, Edgar H H Wong, Jenny Tran, Greg G Qiao, Frank Caruso
Particle-cell interactions are governed by, among other factors, the composition and surface properties of the particles. Herein, we report the preparation of various polymer capsules with different compositions and properties via atom transfer radical polymerization mediated continuous assembly of polymers (CAPATRP), where the cellular interactions of these capsules, particularly fouling and specific targeting, are examined by flow cytometry and deconvolution microscopy. Acrylated eight-arm poly(ethylene glycol) (8-PEG) and poly(N-(2-hydroxypropyl)-methacrylamide) (PHPMA) as well as methacrylated hyaluronic acid (HA), poly(glutamic acid) (PGA), and poly(methacrylic acid) (PMA) are used as macro-cross-linkers to obtain a range of polymer capsules with different compositions (PEG, PHPMA, HA, PGA, and PMA)...
May 26, 2017: Bioconjugate Chemistry
https://www.readbyqxmd.com/read/28548543/systematic-review-of-clinical-guidance-documents-for-autism-spectrum-disorder-diagnostic-assessment-in-select-regions
#19
Melanie Penner, Evdokia Anagnostou, Lana Y Andoni, Wendy J Ungar
Clinical guidance documents play an important role in ensuring access to high-quality autism spectrum disorder diagnostic assessment practices. The objective was to perform a systematic review of professional association and government clinical guidance documents for autism spectrum disorder diagnostic assessment, analyzing their quality and content. The government search was limited to English-speaking, single-payer, publicly funded health systems. A quality appraisal was conducted by two appraisers using the Appraisal of Guidelines Research and Evaluation, second edition tool...
May 1, 2017: Autism: the International Journal of Research and Practice
https://www.readbyqxmd.com/read/28548488/a-fluorescent-split-aptamer-for-visualizing-rna-rna-assembly-in-vivo
#20
Khalid K Alam, Kwaku D Tawiah, Matthew F Lichte, David Porciani, Donald H Burke
RNA-RNA assembly governs key biological processes and is a powerful tool for engineering synthetic genetic circuits. Characterizing RNA assembly in living cells often involves monitoring fluorescent reporter proteins, which are at best indirect measures of underlying RNA-RNA hybridization events and are subject to additional temporal and load constraints associated with translation and activation of reporter proteins. In contrast, RNA aptamers that sequester small molecule dyes and activate their fluorescence are increasingly utilized in genetically encoded strategies to report on RNA-level events...
May 26, 2017: ACS Synthetic Biology
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