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https://www.readbyqxmd.com/read/28340454/pea-cultivar-and-wheat-residues-affect-carbon-nitrogen-dynamics-in-pea-triticale-intercropping-a-microcosms-approach
#1
Antonella Scalise, Valentini A Pappa, Antonio Gelsomino, Robert M Rees
The underlying mechanisms by which legume cultivars contribute to nitrous oxide (N2O) generation are poorly understood. The aim of the present study was to explore the effects of two pea cultivars (Zero4 and Nitouche) intercropped with triticale, with or without wheat (Triticum aestivum) residues incorporation, on soil C and N dynamics, on bacterial community structure and their links with N2O emissions. Monocrops and bare soil (no plant) treatments were used as an additional control in order to account for the level of mineralisation between treatments...
March 21, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28337023/reconstruction-of-large-scale-defects-with-a-novel-hybrid-scaffold-made-from-poly-l-lactic-acid-nanohydroxyapatite-alendronate-loaded-chitosan-microsphere-in-vitro-and-in-vivo-studies
#2
Hongwei Wu, Pengfei Lei, Gengyan Liu, Yu Shrike Zhang, Jingzhou Yang, Longbo Zhang, Jie Xie, Wanting Niu, Hua Liu, Jianming Ruan, Yihe Hu, Chaoyue Zhang
A chitosan-based microsphere delivery system has been fabricated for controlled release of alendronate (AL). The present study aimed to incorporate the chitosan/hydroxyapatite microspheres-loaded with AL (CH/nHA-AL) into poly(L-lactic acid)/nanohydroxyapatite (PLLA/nHA) matrix to prepare a novel microspheres-scaffold hybrid system (CM-ALs) for drug delivery and bone tissue engineering application. The characteristics of CM-ALs scaffolds containing 10% and 20% CH/nHA-AL were evaluated in vitro, including surface morphology and porosity, mechanical properties, drug release, degradation, and osteogenic differentiation...
March 23, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28335799/convergent-and-sequential-synthesis-designs-implications-for-conducting-and-reporting-systematic-reviews-of-qualitative-and-quantitative-evidence
#3
Quan Nha Hong, Pierre Pluye, Mathieu Bujold, Maggy Wassef
BACKGROUND: Systematic reviews of qualitative and quantitative evidence can provide a rich understanding of complex phenomena. This type of review is increasingly popular, has been used to provide a landscape of existing knowledge, and addresses the types of questions not usually covered in reviews relying solely on either quantitative or qualitative evidence. Although several typologies of synthesis designs have been developed, none have been tested on a large sample of reviews. The aim of this review of reviews was to identify and develop a typology of synthesis designs and methods that have been used and to propose strategies for synthesizing qualitative and quantitative evidence...
March 23, 2017: Systematic Reviews
https://www.readbyqxmd.com/read/28334693/fabrication-of-human-hair-keratin-jellyfish-collagen-eggshell-derived-hydroxyapatite-osteoinductive-biocomposite-scaffolds-for-bone-tissue-engineering-from-waste-to-regenerative-medicine-products
#4
Yavuz Emre Arslan, Tugba Sezgin Arslan, Burak Derkus, Emel Emregul, Kaan C Emregul
In the present study, we aimed at fabricating an osteoinductive biocomposite scaffold using keratin obtained from human hair, jellyfish collagen and eggshell-derived nano-sized spherical hydroxyapatite (nHA) for bone tissue engineering applications. Keratin, collagen and nHA were characterized with the modified Lowry method, free-sulfhydryl groups and hydroxyproline content analysis, sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE), attenuated total reflectance-fourier transform infrared spectroscopy (ATR-FTIR) and thermal gravimetric analysis (TGA) which confirmed the success of the extraction and/or isolation processes...
March 18, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/28323699/use-of-nanocrystalline-hydroxyapatite-with-autologous-bma-and-local-bone-in-the-lumbar-spine-a-retrospective-ct-analysis-of-posterolateral-fusion-results
#5
Stephen Robbins, Carl Lauryssen, Matthew N Songer
STUDY DESIGN: A retrospective, multicenter, medical record review and independent analysis of computed tomographic scans was performed in 46 patients to determine radiographic arthrodesis rates after 1-segment, 2-segment, or 3-segment instrumented posterolateral fusions (PLF) using autograft, bone marrow aspirate (BMA), and a nanocrystalline hydroxyapatite bone void filler (nHA). OBJECTIVE: To determine the radiographic arthrodesis rates after instrumented lumbar PLF using local autograft, BMA, and nHA...
April 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28298977/effect-of-addition-of-nano-hydroxyapatite-particles-on-wear-of-resin-modified-glass-ionomer-by-tooth-brushing-simulation
#6
Kiana Poorzandpoush, Ladan-Ranjbar Omrani, Shiva H Jafarnia, Parisa Golkar, Mohammad Atai
BACKGROUND: Recently, incorporation of nanohydroxyapatite (NHA) has been suggested to improve the mechanical properties of glass ionomers (GIs). This study aimed to assess the effect of addition of NHA on wear of resin modified glass ionomer (RMGI) by tooth brushing simulation. MATERIAL AND METHODS: In this in vitro, experimental study, NHA in 1, 2, 5, 7 and 10wt% concentrations was added to Fuji II LC RMGI powder, and 48 samples (5×5mm) in five experimental and one control group (n=8) were fabricated...
March 2017: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/28293185/hypoconnectivity-of-resting-state-networks-in-persons-with-aphasia-compared-with-healthy-age-matched-adults
#7
Chaleece W Sandberg
Aphasia is a language disorder affecting more than one million people in the US. While language function has traditionally been the focus of neuroimaging research, other cognitive functions are affected in this population, which has implications not only for those specific processes but also for the interaction of language and other cognitive functions. Resting state fMRI (rs-fMRI) is a practical and informative way to explore and characterize general cognitive engagement and/or health in this population, but it is currently underutilized...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28287572/rapid-mix-preparation-of-bioinspired-nanoscale-hydroxyapatite-for-biomedical-applications
#8
Caroline J Wilcock, Piergiorgio Gentile, Paul V Hatton, Cheryl A Miller
Hydroxyapatite (HA) has been widely used as a medical ceramic due to its good biocompatibility and osteoconductivity. Recently there has been interest regarding the use of bioinspired nanoscale hydroxyapatite (nHA). However, biological apatite is known to be calcium-deficient and carbonate-substituted with a nanoscale platelet-like morphology. Bioinspired nHA has the potential to stimulate optimal bone tissue regeneration due to its similarity to bone and tooth enamel mineral. Many of the methods currently used to fabricate nHA both in the laboratory and commercially, involve lengthy processes and complex equipment...
February 23, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28267662/microstructure-and-property-evolutions-of-titanium-nano-hydroxyapatite-composites-in-situ-prepared-by-selective-laser-melting
#9
Changjun Han, Qian Wang, Bo Song, Wei Li, Qingsong Wei, Shifeng Wen, Jie Liu, Yusheng Shi
Titanium (Ti)-hydroxyapatite (HA) composites have the potential for orthopedic applications due to their favorable mechanical properties, excellent biocompatibility and bioactivity. In this work, the pure Ti and nano-scale HA (Ti-nHA) composites were in-situ prepared by selective laser melting (SLM) for the first time. The phase, microstructure, surface characteristic and mechanical properties of the SLM-processed Ti-nHA composites were studied by X-ray diffraction, transmission electron microscope, atomic force microscope and tensile tests, respectively...
February 20, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28259931/cd164-regulates-proliferation-and-apoptosis-by-targeting-pten-in-human-glioma
#10
Ming Tu, Lin Cai, Weiming Zheng, Zhipeng Su, Yong Chen, Songtao Qi
Cluster of differentiation 164 (CD164), a sialomucin, has been demonstrated to be involved in the regulation of proliferation, apoptosis, adhesion and differentiation in multiple cancers. CD164 is regarded to be a potential promotor of tumor growth. However, the involvement of CD164 in human glioma proliferation and apoptosis remains unknown. The aim of the present study was to investigate the expression and oncogenic function of CD164 in normal human astrocytes (NHA) and glioma cells in vitro and in vivo...
April 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28256792/the-effect-of-increasing-the-pore-size-of-nanofibrous-scaffolds-on-the-osteogenic-cell-culture-using-a-combination-of-sacrificial-agent-electrospinning-and-ultrasonication
#11
Mahdiyeh Aghajanpoor, Sameereh Hashemi-Najafabadi, Mohamadreza Baghaban-Eslaminejad, Fatemeh Bagheri, Seyyed Mohammad Mousavi, Foruogh Azam Sayyahpour
One of the major problems associated with the electrospun scaffolds is their small pore size, which limits the cellular infiltration for bone tissue engineering. In this study, the effect of increasing the pore size on cellular infiltration was studied in poly‌caprolactone (PCL)/nanohydroxyapatite (nHA) electrospun scaffolds, which were modified using ultrasonication, co-electrospinning with poly (ethylene oxide) (PEO), and a combination of both. Ultrasonic process was optimized by central composite design (CCD)...
March 3, 2017: Journal of Biomedical Materials Research. Part A
https://www.readbyqxmd.com/read/28231645/the-effect-of-different-sagittal-angles-of-the-tibial-guide-on-aperture-widening-of-the-tibial-tunnel-during-modified-transtibial-anterior-cruciate-ligament-reconstruction-a-randomized-in-vivo-study
#12
Young Chan Kim, Tulyapruek Tawonsawatruk, Hyeong Hwa Woon, Ji Woong Yum, Myung Jin Shin, Rodolfo S Bravo, Kyung Wook Nha
Purpose: The effect of sagittal plane angle of the tibial tunnel on the severity of tibial intra-articular aperture expansion caused by iatrogenic re-reaming in anterior cruciate ligament (ACL) reconstruction using a modified transtibial technique is unknown. The purpose of this study was to compare the severity of intra-articular aperture widening at different angles (40°, 45°, and 50°) of the tibial guide (TG). Materials and Methods: Ninety-seven patients who underwent modified transtibial ACL reconstruction were randomly allocated to TG 40°, 45°, and 50° groups...
March 1, 2017: Knee Surgery & related Research
https://www.readbyqxmd.com/read/28223126/targeted-inhibition-of-hdac8-increases-the-doxorubicin-sensitivity-of-neuroblastoma-cells-via-up-regulation-of-mir-137
#13
Gang Zhao, Guoliang Wang, Hongmin Bai, Tiandong Li, Fanghe Gong, Huan Yang, Jinchong Wen, Weimin Wang
Histone deacetylases (HDACs) have been suggested to be potential therapeutic targets for cancer treatment. Recent studies revealed that HDAC8 expression was associated with poor prognostic markers and poor overall survival rate of neuroblastoma (NB). Our present study revealed that among the four members of class I HDACs, HDAC8 is significantly over expressed in NB cells as compared with the normal fibroblast 3T3 cells or primary normal human astrocytes (NHA) cells. Targeted inhibition of HDAC8 by its specific siRNA (si-HDAC8) can inhibit the in vitro growth of NB cells...
February 20, 2017: European Journal of Pharmacology
https://www.readbyqxmd.com/read/28222045/validation-of-scaffold-design-optimization-in-bone-tissue-engineering-finite-element-modeling-versus-designed-experiments
#14
Nicholas Uth, Jens Mueller, Byran Smucker, Azizeh-Mitra Yousefi
This study reports the development of biological/synthetic scaffolds for bone tissue engineering (TE) via 3D bioplotting. These scaffolds were composed of poly(L-lactic-co-glycolic acid) (PLGA), type I collagen, and nano-hydroxyapatite (nHA) in an attempt to mimic the extracellular matrix of bone. The solvent used for processing the scaffolds was 1,1,1,3,3,3-hexafluoro-2-propanol. The produced scaffolds were characterized by scanning electron microscopy, microcomputed tomography, thermogravimetric analysis, and unconfined compression test...
February 21, 2017: Biofabrication
https://www.readbyqxmd.com/read/28220723/ethical-issues-surrounding-the-use-of-modern-human-remains-for-research-in-south-africa
#15
N Briers, J J Dempers
Chapter 8 of the South African National Health Act 61 of 2003 (NHA) that deals with the donation of human tissue was promulgated in 2012. The new Act is perceived to impose restrictions on low-risk research involving human remains. This study aimed to identify the issues raised by a research ethics committee (REC) when reviewing protocols where human remains are used as data source. REC minutes from 2009 to 2014 were reviewed, and issues raised by the committee were categorized. In total, 127 protocols submitted to the committee over 6 years involved human remains...
February 2017: Journal of Empirical Research on Human Research Ethics: JERHRE
https://www.readbyqxmd.com/read/28220190/open-wedge-high-tibial-osteotomy-versus-unicompartmental-knee-arthroplasty-no-difference-in-progression-of-patellofemoral-joint-arthritis
#16
Kwang-Jun Oh, Young Chan Kim, Jong Seong Lee, Yong Suk Chang, Gautam M Shetty, Kyung Wook Nha
PURPOSE: The purpose of this retrospective comparative study was to evaluate and compare, radiographically and clinically, progression of osteoarthritis (OA) in the patellofemoral (PF) compartment after open-wedge high tibial osteotomy (OWHTO), and unicompartmental knee arthroplasty (UKA) over a minimum follow-up of 5 years. METHODS: In this study, 42 knees in an OWHTO group were compared with 59 knees in a UKA group in terms of radiographic parameters, such as the grading system for OA progression in the PF compartment, and clinical parameters, such as the PF pain and function scores over a minimum follow-up of 5 years...
March 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28187650/amended-diagnosis-of-the-genus-i-nannodiaptomus-i-copepoda-calanoida-%C3%A2-based-on-redescription-of-i-n-phongnhaensis-i-and-description-of-a-new-species-from-caves-in-central-vietnam
#17
Duc Luong Tran, Anton Brancelj
Nannodiaptomus phongnhaensis Dang & Ho, 2001, an endemic stygobiotic diaptomid from Vietnam and the type species of the genus Nannodiaptomus Dang & Ho, 2001, is redescribed on the basis of a new material from its type locality: Hang Phong Nha Cave, Quang Binh province, central Vietnam. We also designated a neotype, because the type material has been lost. The diagnosis of the genus is amended, based on the description of the neotype. The taxonomic position of the genus in the subfamily Speodiaptominae is proposed, and its relationships with other genera of this subfamily are discussed...
January 19, 2017: Zootaxa
https://www.readbyqxmd.com/read/28187630/sternaspidae-annelida-sedentaria-from-vietnam-with-description-of-three-new-species-and-clarification-of-some-morphological-features
#18
Anna E Zhadan, Alexander B Tzetlin, Sergio I Salazar-Vallejo
Five sternaspid species were found near Vietnam shores: Sternaspis britayevi sp. nov., S. costata von Marenzeller, 1879, S. nana sp. nov., S. papillosa sp. nov., and S. spinosa Sluiter 1882. Sternaspis britayevi is described from the shallow water in Vietnam inhabiting soft bottoms; it resembles S. spinosa described from Java and S. thorsoni Sendall & Salazar-Vallejo, 2013 described from the Persian Gulf, but differs in having a medially projected and markedly ribbed fan of the ventro-caudal shield and nearly parallel, distally widened and rounded branchial plates...
January 25, 2017: Zootaxa
https://www.readbyqxmd.com/read/28152379/selective-transduction-of-astrocytic-and-neuronal-cns-subpopulations-by-lentiviral-vectors-pseudotyped-with-chikungunya-virus-envelope
#19
Ioanna Eleftheriadou, Michael Dieringer, Xuan Ying Poh, Julia Sanchez-Garrido, Yunan Gao, Argyro Sgourou, Laura E Simmons, Nicholas D Mazarakis
Lentiviral vectors are gene delivery vehicles that integrate into the host genome of dividing and non-dividing mammalian cells facilitating long-term transgene expression. Lentiviral vector versatility is greatly increased by incorporating heterologous viral envelope proteins onto the vector particles instead of the native envelope, conferring on these pseudotyped vectors a modified tropism and host range specificity. We investigated the pseudotyping efficiency of HIV-1 based lentiviral vectors with alphaviral envelope proteins from the Chikungunya Virus (CHIKV-G) and Sindbis Virus (SINV-G)...
January 23, 2017: Biomaterials
https://www.readbyqxmd.com/read/28140360/assembling-of-electrospun-meshes-into-three-dimensional-porous-scaffolds-for-bone-repair
#20
Juqing Song, Guanglin Zhu, Lin Wang, Geng An, Xuetao Shi, Yingjun Wang
Technical limitations of traditional electrospinning make it hard to produce three-dimensional (3D) scaffolds with hierarchical pore structures. Here, porous polycaprolactone (PCL) nanofiber meshes with different nano-hydroxyapatite (nHA) concentrations were prepared by electrospinning with stainless steel mesh as the collector, and 3D porous nanofiber scaffolds were fabricated via layer-by-layer assembly with a special binder (18% PCL/DCM solution). The single layer nanofiber mesh possessed very regular morphology with a hollow structure, and the nHA was not only embedded in the nanofiber but also exposed on the surfaces of the fiber, resulting in the improved surface chemical properties...
February 14, 2017: Biofabrication
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