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https://www.readbyqxmd.com/read/28716286/neurosarcoidosis-according-to-zajicek-and-scolding-criteria-15-probable-and-definite-cases-their-treatment-and-outcomes
#1
Gonçalo Cação, Ana Branco, Mariana Meireles, José Eduardo Alves, Andrea Mateus, Ana Martins Silva, Ernestina Santos
INTRODUCTION: Neurosarcoidosis occurs in about 5% to 15% of patients with sarcoidosis. The purpose of this study was to identify and characterize a cohort of neurosarcoidosis patients and to review the largest previously reported neurosarcoidosis case series. METHODS: This retrospective study enrolled all patients with the diagnosis of probable or definitive neurosarcoidosis according to Zajicek and Scolding criteria, followed at the neurology department of a tertiary center in Portugal from January 1989 to December 2015...
August 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28712318/phylogenetic-studies-and-comparative-chloroplast-genome-analyses-elucidate-the-basal-position-of-halophyte-nitraria-sibirica-nitrariaceae-in-the-sapindales
#2
Lu Lu, Xia Li, Zhaodong Hao, Liming Yang, Jingbo Zhang, Ye Peng, Haibin Xu, Ye Lu, Jin Zhang, Jisen Shi, Jinhui Chen, Tielong Cheng
Nitraria sibirica is a halophyte and belongs to the family Nitrariaceae. The chloroplast genome of Nitraria sibirica (159,466 bp) has a quadripartite structure, which consists of a large single-copy (87,914 bp) region, a small single-copy (18,316 bp) region, and a pair of inverted repeats (26,618 bp). Sequencing analyses indicate that the chloroplast genome contains 113 distinct genes, including 79 peptide-coding genes, 30 transfer RNA genes, and 4 ribosomal RNA genes. We also identified 105 perfect simple sequence repeats, 12 most divergent non-coding regions, and 6 most divergent coding regions when compared to the chloroplast genomes of the Sapindales plants...
July 15, 2017: Mitochondrial DNA. Part A. DNA Mapping, Sequencing, and Analysis
https://www.readbyqxmd.com/read/28702382/epidemiology-of-pelvic-ring-fractures-and-injuries
#3
Gilberto José Cação Pereira, Erick Ribeiro Damasceno, Daniel Innocenti Dinhane, Francisco Marques Bueno, Jaqueline Bartelega Rodrigues Leite, Bruno da Costa Ancheschi
OBJECTIVE: This study evaluated the pelvic ring fractures and injuries in patients admitted to and treated at this ward between August, 2012 and January, 2014. METHODS: 66 patients were submitted to treatment protocols according to their age, gender, skin color, injury mechanism, location of the trauma, classification of their injuries, emergency intervention, associated injuries, injured side of the body, treatment, and mortality. The most relevant data were classified according to statistic procedures, such as Goodman's association test...
May 2017: Revista Brasileira de Ortopedia
https://www.readbyqxmd.com/read/28683423/heavy-metal-accumulation-in-leaves-and-beans-of-cacao-theobroma-cacao-l-in-major-cacao-growing-regions-in-peru
#4
Enrique Arévalo-Gardini, Cesar O Arévalo-Hernández, Virupax C Baligar, Zhenli L He
Peru is one of the leading exporters of organic cacao beans in the world. However, the accumulation of heavy metals in cacao beans represents a problem for cocoa bean export and chocolate quality. The aim of this study was to investigate the distribution and accumulation of heavy metals in cacao leaves and cocoa beans in three major cacao growing regions of Peru. The study was conducted in cacao plantations of 10 to 15years old in three regions of Peru: North (Regions of Tumbes, Piura, Cajamarca, and Amazonas); Center (Regions of Huánuco and San Martin) and South (Junin and Cuzco)...
July 3, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28682071/comprehensive-chemical-fingerprinting-of-high-quality-cocoa-at-early-stages-of-processing-effectiveness-of-combined-untargeted-and-targeted-approaches-for-classification-and-discrimination
#5
Federico Magagna, Alessandro Guglielmetti, Erica Liberto, Stephen E Reichenbach, Elena Allegrucci, Guido Gobino, Carlo Bicchi, Chiara Cordero
This study investigates chemical information of volatile fractions of high-quality cocoa (Theobroma cacao L. Malvaceae) from different origins (Mexico, Ecuador, Venezuela, Columbia, Java, Trinidad, and Sao Tomè) produced for fine chocolate. This study explores the evolution of the entire pattern of volatiles in relation to cocoa processing (raw, roasted, steamed, and ground beans). Advanced chemical fingerprinting (e.g., combined untargeted and targeted fingerprinting) with comprehensive two-dimensional gas chromatography coupled with mass spectrometry allows advanced pattern recognition for classification, discrimination, and sensory-quality characterization...
July 18, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28679727/exposure-to-the-leaf-litter-microbiome-of-healthy-adults-protects-seedlings-from-pathogen-damage
#6
Natalie Christian, Edward Allen Herre, Luis C Mejia, Keith Clay
It is increasingly recognized that microbiota affect host health and physiology. However, it is unclear what factors shape microbiome community assembly in nature, and how microbiome assembly can be manipulated to improve host health. All plant leaves host foliar endophytic fungi, which make up a diverse, environmentally acquired fungal microbiota. Here, we experimentally manipulated assembly of the cacao tree (Theobroma cacao) fungal microbiome in nature and tested the effect of assembly outcome on host health...
July 12, 2017: Proceedings. Biological Sciences
https://www.readbyqxmd.com/read/28646332/a-rational-approach-for-the-improvement-of-biomass-production-and-lipid-profile-in-cacao-cell-suspensions
#7
Adriana María Gallego Rúa, Luisa Fernanda Rojas, Aura Ines Urrea Trujillo, Oriana Parra Zuleta, Cristian David Correa Alvarez, Lucía Atehortúa Garcés
Cocoa butter (CB) is produced in the seeds of Theobroma cacao representing 50% of its dry weight. The lipid composition plays an important role in the physicochemical, rheological, and sensory properties of the CB, making this fat a valuable resource for the production of chocolates, cosmetics, and pharmaceuticals. In this paper, are described experimental strategies used for a rational improvement of biomass production and fatty acids in cacao cell suspension cultures. First, the lipid profile in four cacao varieties is characterized, and then, one variety is selected to induce cell suspensions using a direct method without previous establishment of a callus phase...
June 23, 2017: Bioprocess and Biosystems Engineering
https://www.readbyqxmd.com/read/28628670/combining-ability-heritability-and-genotypic-relations-of-different-physiological-traits-in-cacao-hybrids
#8
Allan Silva Pereira, Alex-Alan Furtado de Almeida, Márcia Christina da Silva Branco, Marcio Gilberto Cardoso Costa, Dario Ahnert
Selecting parents and evaluating progenies is a very important step in breeding programs and involves approaches such as understanding the initial stages of growth and characterizing the variability among genotypes for different parameters, such as physiological, growth, biomass partitioning and nutrient translocation to the aerial part. In these cases, facilitating tools can be used to understand the involved gene dynamics, such as diallel crosses and genetic and phenotypic correlations. Our main hypothesis is that the contrasting phenotypes of these parental genotypes of cocoa used are due to genetic factors, and progenies derived from crosses of these parental genotypes are useful for breeding programs related to plant architecture, physiological parameters and translocation of mineral nutrients...
2017: PloS One
https://www.readbyqxmd.com/read/28614756/photosynthetic-antioxidative-molecular-and-ultrastructural-responses-of-young-cacao-plants-to-cd-toxicity-in-the-soil
#9
Romária Pereira de Araújo, Alex-Alan Furtado de Almeida, Lidiane Silva Pereira, Pedro A O Mangabeira, José Olimpio Souza, Carlos P Pirovani, Dário Ahnert, Virupax C Baligar
Cadmium (Cd) is a highly toxic metal for plants, even at low concentrations in the soil. The annual production of world cocoa beans is approximately 4 million tons. Most of these fermented and dried beans are used in the manufacture of chocolate. Recent work has shown that the concentration of Cd in these beans has exceeded the critical level (0.6mgkg(-1) DM). The objective of this study was to evaluate the toxicity of Cd in young plants of CCN 51 cacao genotype grown in soil with different concentrations of Cd (0, 0...
June 10, 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/28600559/transcriptome-of-pterospermum-kingtungense-provides-implications-on-the-mechanism-underlying-its-rapid-vegetative-growth-and-limestone-adaption
#10
Yandong Ren, Yanan Zhu, Qi Wang, Hui Xiang, Boyi Wang
Pterospermum kingtungense C.Y.Wu ex Hsue is a typical tree species living in the relatively adverse limestone habitat. Due to its excellent wood quality and big size, it is an important timber resource which caused its endangered. We firstly provide the data resources by reporting an annotated transcriptome assembly. 203 million unique Illumina RNA-seq reads were produced with totally 50,333 transcripts, among which 48,778 transcripts were annotated. By a global comparison of homology between P. kingtungense and cacao, we identified 9,507 single copy orthologues and 990 P...
June 9, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28581254/tree-spacing-impacts-the-individual-incidence-of-moniliophthora-roreri-disease-in-cacao-agroforests
#11
Marie Ange Ngo Bieng, Laudine Alem, Chloé Curtet, Philippe Tixier
BACKGROUND: Using conventional pesticides in crop protection has raised serious environmental concerns and there is therefore a need for integrated pest management (IPM) methods. In this paper, we found that the spacing of trees can impact disease, which could result in a reduction in pesticide applications and may act as a potential IPM method. We studied Frosty Pod Rot (FPR) in 20 cacao agroforests in Costa Rica (Upala region). RESULTS: Using a generalized linear mixed model, we analyzed the impact of the neighborhood composition and distance from a studied cacao individual on its individual FPR incidence...
June 5, 2017: Pest Management Science
https://www.readbyqxmd.com/read/28577147/enhancement-of-sorption-capacity-of-cocoa-shell-biomass-modified-with-non-thermal-plasma-for-removal-of-both-cationic-and-anionic-dyes-from-aqueous-solution
#12
Brice Takam, Elie Acayanka, Georges Y Kamgang, Merlin T Pedekwang, Samuel Laminsi
Removal of cationic dye, Azur II, and anionic dye, Reactive Red 2 (RR-2) from aqueous solutions, has been successfully achieved by using a modified agricultural biomaterial waste: cocoa shell husk (Theobroma cacao) treated by gliding arc plasma (CPHP). The biomass in its natural form CPHN and modified form CPHP was characterized by infrared spectroscopy (FTIR), thermogravimetric analysis (TGA), scanning electron microscopy (SEM), and point of zero charge (pHpzc). Experimental variables such as initial pH, contact time, and temperature were optimized for adsorptive characteristics of CPHN and CPHP...
July 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28576408/browning-effects-of-epicatechin-on-adipocytes-and-white-adipose-tissue
#13
Claudia Elena Varela, Alonso Rodriguez, Mirza Romero-Valdovinos, Patricia Mendoza-Lorenzo, Christina Mansour, Guillermo Ceballos, Francisco Villarreal, Israel Ramirez-Sanchez
In this study, we demonstrate that (-)-epicatechin (Epi), a cacao flavanol, induces the browning of fat by promoting mitochondrial biogenesis, enhancing indicators of mitochondrial structure and function, increasing fatty acid metabolism and upregulating the expression of brown adipose tissue-specific proteins in a high-fat diet mouse model of obesity and in cultured human adipocytes. Epi treatment significantly improved mitochondrial function, as measured by citrate synthase activity, and also reduced protein acetylation of total and specific regulators in both adipose tissue and human adipocytes...
May 30, 2017: European Journal of Pharmacology
https://www.readbyqxmd.com/read/28572069/consumption-of-dark-chocolate-attenuates-subsequent-food-intake-compared-with-milk-and-white-chocolate-in-postmenopausal-women
#14
Channa E Marsh, Daniel J Green, Louise H Naylor, Kym J Guelfi
BACKGROUND: Chocolate has a reputation for contributing to weight gain due to its high fat, sugar and calorie content. However, the effect of varying concentrations of cocoa in chocolate on energy intake and appetite is not clear. OBJECTIVE: To compare the acute effect of consuming an isocaloric dose of dark, milk and white chocolate on subsequent energy intake, appetite and mood in postmenopausal women. METHODS: Fourteen healthy postmenopausal women (57...
May 29, 2017: Appetite
https://www.readbyqxmd.com/read/28554504/predictions-of-space-radiation-fatality-risk-for-exploration-missions
#15
Francis A Cucinotta, Khiet To, Eliedonna Cacao
In this paper we describe revisions to the NASA Space Cancer Risk (NSCR) model focusing on updates to probability distribution functions (PDF) representing the uncertainties in the radiation quality factor (QF) model parameters and the dose and dose-rate reduction effectiveness factor (DDREF). We integrate recent heavy ion data on liver, colorectal, intestinal, lung, and Harderian gland tumors with other data from fission neutron experiments into the model analysis. In an earlier work we introduced distinct QFs for leukemia and solid cancer risk predictions, and here we consider liver cancer risks separately because of the higher RBE's reported in mouse experiments compared to other tumors types, and distinct risk factors for liver cancer for astronauts compared to the U...
May 2017: Life Sciences in Space Research
https://www.readbyqxmd.com/read/28546652/chimpanzees-pan-troglodytes-flexibly-use-introduced-species-for-nesting-and-bark-feeding-in-a-human-dominated-habitat
#16
Maureen S McCarthy, Jack D Lester, Craig B Stanford
As habitat loss and fragmentation place growing pressure on endangered nonhuman primate populations, researchers find increasing evidence for novel responses in behavior. In western Uganda between the Budongo and Bugoma Forests, chimpanzees (Pan troglodytes schweinfurthii) inhabit a mosaic landscape comprising forest fragments, human settlements, and agricultural land. We recorded nests and feeding evidence of unhabituated chimpanzees in this region over a 12-mo period. We found extensive evidence of nesting in introduced tree species, including eucalyptus (Eucalyptus grandis), guava (Psidium guajava), cocoa (Theobroma cacao), and Caribbean pine (Pinus caribaea)...
2017: International Journal of Primatology
https://www.readbyqxmd.com/read/28540183/the-draft-genome-of-corchorus-olitorius-cv-jro-524-navin
#17
Debabrata Sarkar, Ajay Kumar Mahato, Pratik Satya, Avijit Kundu, Sangeeta Singh, Pawan Kumar Jayaswal, Akshay Singh, Kaushlendra Bahadur, Sasmita Pattnaik, Nisha Singh, Avrajit Chakraborty, Nur Alam Mandal, Debajeet Das, Tista Basu, Amitha Mithra Sevanthi, Dipnarayan Saha, Subhojit Datta, Chandan Sourav Kar, Jiban Mitra, Karabi Datta, Pran Gobinda Karmakar, Tilak Raj Sharma, Trilochan Mohapatra, Nagendra Kumar Singh
Here, we present the draft genome (377.3 Mbp) of Corchorus olitorious cv. JRO-524 (Navin), which is a leading dark jute variety developed from a cross between African (cv. Sudan Green) and indigenous (cv. JRO-632) types. We predicted from the draft genome a total of 57,087 protein-coding genes with annotated functions. We identified a large number of 1765 disease resistance-like and defense response genes in the jute genome. The annotated genes showed the highest sequence similarities with that of Theobroma cacao followed by Gossypium raimondii...
June 2017: Genomics Data
https://www.readbyqxmd.com/read/28532079/nerve-growth-factor-loaded-heparinized-cationic-solid-lipid-nanoparticles-for-regulating-membrane-charge-of-induced-pluripotent-stem-cells-during-differentiation
#18
Yung-Chih Kuo, Rajendiran Rajesh
Nerve growth factor (NGF)-loaded heparinized cationic solid lipid nanoparticles (NGF-loaded HCSLNs) were developed using heparin-stearic acid conjugate, cacao butter, cholesterol, stearylamine (SA), and esterquat 1 (EQ 1). The effect of cationic lipids and lipid matrix composition on the particle size, particle structure, surface molecular composition, chemical structure, electrophoretic mobility, and zeta potential of HCSLNs was investigated. The effect of HCSLNs on the membrane charge of induced pluripotent stem cells (iPSCs) was also studied...
August 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28500351/non-targeted-effects-models-predict-significantly-higher-mars-mission-cancer-risk-than-targeted-effects-models
#19
Francis A Cucinotta, Eliedonna Cacao
Cancer risk is an important concern for galactic cosmic ray (GCR) exposures, which consist of a wide-energy range of protons, heavy ions and secondary radiation produced in shielding and tissues. Relative biological effectiveness (RBE) factors for surrogate cancer endpoints in cell culture models and tumor induction in mice vary considerable, including significant variations for different tissues and mouse strains. Many studies suggest non-targeted effects (NTE) occur for low doses of high linear energy transfer (LET) radiation, leading to deviation from the linear dose response model used in radiation protection...
May 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28473262/the-tea-tree-genome-provides-insights-into-tea-flavor-and-independent-evolution-of-caffeine-biosynthesis
#20
En-Hua Xia, Hai-Bin Zhang, Jun Sheng, Kui Li, Qun-Jie Zhang, Changhoon Kim, Yun Zhang, Yuan Liu, Ting Zhu, Wei Li, Hui Huang, Yan Tong, Hong Nan, Cong Shi, Chao Shi, Jian-Jun Jiang, Shu-Yan Mao, Jun-Ying Jiao, Dan Zhang, Yuan Zhao, You-Jie Zhao, Li-Ping Zhang, Yun-Long Liu, Ben-Ying Liu, Yue Yu, Sheng-Fu Shao, De-Jiang Ni, Evan E Eichler, Li-Zhi Gao
Tea is the world's oldest and most popular caffeine-containing beverage with immense economic, medicinal, and cultural importance. Here, we present the first high-quality nucleotide sequence of the repeat-rich (80.9%), 3.02-Gb genome of the cultivated tea tree Camellia sinensis. We show that an extraordinarily large genome size of tea tree is resulted from the slow, steady, and long-term amplification of a few LTR retrotransposon families. In addition to a recent whole-genome duplication event, lineage-specific expansions of genes associated with flavonoid metabolic biosynthesis were discovered, which enhance catechin production, terpene enzyme activation, and stress tolerance, important features for tea flavor and adaptation...
June 5, 2017: Molecular Plant
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