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https://www.readbyqxmd.com/read/27908685/royal-jelly-supplemented-soybean-lecithin-based-extenders-improve-post-thaw-quality-and-incubation-resilience-of-goat-spermatozoa
#1
Selim Alcay, M Berk Toker, N Tekin Onder, Elif Gokce
The aim of the present study was to evaluate different concentrations of royal jelly (RJ) supplemented extenders for post-thaw quality and incubation resilience of goat spermatozoa. Semen samples were collected from five goats. Pooled semen were diluted with soybean lecithin-based extender without RJ (control) or supplemented with different concentrations (0.25, 0.5 and 0.75%) of RJ (RJ0.25, RJ0.5, RJ0.75 respectively), at a final concentration of 150 × 10(6) spermatozoon/mL. Semen samples were assessed for sperm motility, plasma membrane integrity using hypoosmotic swelling test (HOST) damaged acrosome using FITC-Pisum sativum agglutinin (PSA-FITC) and DNA integrity using terminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling (TUNEL)...
November 28, 2016: Cryobiology
https://www.readbyqxmd.com/read/27901009/occupational-asthma-caused-by-inhalable-royal-jelly-and-its-cross-reactivity-with-honeybee-venom
#2
Li-Sha Li, Kai Guan
No abstract text is available yet for this article.
2016: Chinese Medical Journal
https://www.readbyqxmd.com/read/27890887/royal-jelly-improves-hyperglycemia-in-obese-diabetic-kk-ay-mice
#3
Mei Yoshida, Kaori Hayashi, Risa Watadani, Yoshiyasu Okano, Keiya Tanimura, Jun Kotoh, Daiki Sasaki, Kozo Matsumoto, Akihiko Maeda
The study examined whether royal jelly (RJ) can prevent obesity and ameliorate hyperglycemia in type 2 diabetes. This study utilized obese/diabetic KK-Ay mice. RJ (10 mg/kg) was administered by oral gavage. Body weight, plasma glucose and insulin levels were measured. mRNA and protein levels were determined using quantitative reverse transcription polymerase chain reaction and western blotting, respectively. Four weeks of RJ administration improved hyperglycemia and partially suppressed body weight gain, although the latter effect did not reach statistical significance...
November 26, 2016: Journal of Veterinary Medical Science
https://www.readbyqxmd.com/read/27887663/effects-of-royal-jelly-supplementation-on-regulatory-t-cells-in-children-with-sle
#4
Asmaa M Zahran, Khalid I Elsayh, Khaled Saad, Esraa M A Eloseily, Naglaa S Osman, Mohamd A Alblihed, Gamal Badr, Mohamed H Mahmoud
BACKGROUND AND OBJECTIVE: To our knowledge, no previous studies have focused on the immunomodulatory effects of fresh royal jelly (RJ) administration on systemic lupus erythematosus (SLE) in humans. Our aim was to study the effect of fresh RJ administration on the disease course in children with SLE with some immunological markers (CD4(+) and CD8(+) regulatory T cells and T lymphocytes apoptosis). METHODS: This was an open-label study in which 20 SLE children received 2 g of freshly prepared RJ daily, for 12 weeks...
2016: Food & Nutrition Research
https://www.readbyqxmd.com/read/27865886/social-regulation-of-ageing-by-young-workers-in-the-honey-bee-apis-mellifera
#5
Michael Eyer, Benjamin Dainat, Peter Neumann, Vincent Dietemann
Organisms' lifespans are modulated by both genetic and environmental factors. The lifespan of eusocial insects is determined by features of the division of labor, which itself is influenced by social regulatory mechanisms. In the honey bee, Apis mellifera, the presence of brood and of old workers carrying out foraging tasks are important social drivers of ageing, but the influence of young adult workers is unknown, as it has not been experimentally teased apart from that of brood. In this study, we test the role of young workers in the ageing of their nestmates...
November 16, 2016: Experimental Gerontology
https://www.readbyqxmd.com/read/27847405/in-vitro-anti-inflammatory-effects-of-three-fatty-acids-from-royal-jelly
#6
Yi-Fan Chen, Kai Wang, Yan-Zheng Zhang, Yu-Fei Zheng, Fu-Liang Hu
Trans-10-hydroxy-2-decenoic acid (10-H2DA), 10-hydroxydecanoic acid (10-HDAA), and sebacic acid (SEA) are the three major fatty acids in royal jelly (RJ). Previous studies have revealed several pharmacological activities of 10-H2DA and 10-HDAA, although the anti-inflammatory effects and underlying mechanisms by which SEA acts are poorly understood. In the present study, we evaluated and compared the in vitro anti-inflammatory effects of these RJ fatty acids in lipopolysaccharide-stimulated RAW 264.7 macrophages...
2016: Mediators of Inflammation
https://www.readbyqxmd.com/read/27743422/food-to-some-poison-to-others-honeybee-royal-jelly-and-its-growth-inhibiting-effect-on-european-foulbrood-bacteria
#7
Thomas V Vezeteu, Otilia Bobiş, Robin F A Moritz, Anja Buttstedt
Honeybee colonies (Apis mellifera) serve as attractive hosts for a variety of pathogens providing optimal temperatures, humidity, and an abundance of food. Thus, honeybees have to deal with pathogens throughout their lives and, even as larvae they are affected by severe brood diseases like the European Foulbrood caused by Melissococcus plutonius. Accordingly, it is highly adaptive that larval food jelly contains antibiotic compounds. However, although food jelly is primarily consumed by bee larvae, studies investigating the antibiotic effects of this jelly have largely concentrated on bacterial human diseases...
October 14, 2016: MicrobiologyOpen
https://www.readbyqxmd.com/read/27736245/improvement-of-neurological-disorders-in-postmenopausal-model-rats-by-administration-of-royal-jelly
#8
A Minami, H Matsushita, D Ieno, Y Matsuda, Y Horii, A Ishii, T Takahashi, H Kanazawa, A Wakatsuki, T Suzuki
OBJECTIVE: Royal jelly (RJ) from honeybees (Apis mellifera) has estrogenic activity. Estrogen deficiency after menopause leads to a high risk of memory impairment and depression as well as metabolic syndrome and osteoporosis. We here investigated the effect of RJ on memory impairment and depression-like behaviors in ovariectomized (OVX) rats. METHODS: OVX rats were administered with RJ for 82 days. Hippocampus-dependent spatial memory and depression-like behaviors were assessed by the Morris water maze test and the forced swimming test, respectively...
October 13, 2016: Climacteric: the Journal of the International Menopause Society
https://www.readbyqxmd.com/read/27721892/quantitative-analysis-of-apisin-a-major-protein-unique-to-royal-jelly
#9
Takako Furusawa, Yasuko Arai, Kenji Kato, Kenji Ichihara
Apisin, a protein that is unique to royal jelly (RJ), is known to compose the greater part of the RJ proteins and to exist as a heterooligomer containing major royal jelly protein 1 and apisimin. However, few reports on the methods for quantifying apisin have been published. Thus, we attempted to quantify apisin using HPLC, a widely used analytical technique, as described below. Isoelectric precipitation and size-exclusion chromatography were used to obtain the purified protein, which was identified as apisin by SDS-PAGE and LC-MS analyses...
2016: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/27715425/production-of-knockout-mutants-by-crispr-cas9-in-the-european-honeybee-apis-mellifera-l
#10
Hiroki Kohno, Shota Suenami, Hideaki Takeuchi, Tetsuhiko Sasaki, Takeo Kubo
The European honeybee (Apis mellifera L.) is used as a model organism in studies of the molecular and neural mechanisms underlying social behaviors and/or advanced brain functions. The entire honeybee genome has been sequenced, which has further advanced molecular biologic studies of the honeybee. Functions of genes of interest, however, remain largely to be elucidated in the honeybee due to the lack of effective reverse genetic methods. Moreover, genetically modified honeybees must be maintained under restricted laboratory conditions due to legal restrictions, further complicating the application of reverse genetics to this species...
October 2016: Zoological Science
https://www.readbyqxmd.com/read/27684286/preparation-of-single-cohort-colonies-and-hormone-treatment-of-worker-honeybees-to-analyze-physiology-associated-with-role-and-or-endocrine-system
#11
Takayuki Ueno, Kiyoshi Kawasaki, Takeo Kubo
Honeybee workers are engaged in various tasks related to maintaining colony activity. The tasks of the workers change according to their age (age-related division of labor). Young workers are engaged in nursing the brood (nurse bees), while older workers are engaged in foraging for nectar and pollen (foragers). The physiology of the workers changes in association with this role shift. For example, the main function of the hypopharyngeal glands (HPGs) changes from the secretion of major royal jelly proteins (MRJPs) to the secretion of carbohydrate-metabolizing enzymes...
2016: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/27679827/antioxidant-and-protective-effects-of-royal-jelly-on-histopathological-changes-in-testis-of-diabetic-rats
#12
Elham Ghanbari, Vahid Nejati, Mozafar Khazaei
BACKGROUND: Diabetes is the most common endocrine disease. It has adverse effects on male reproductive function. Royal Jelly (RJ) has antioxidant and anti-diabetic effects and show protective effects against diabetes. OBJECTIVE: This study was conducted to evaluate the effect of RJ on histopathological alterations of the testicular tissue in streptozotocin (STZ)-induced diabetic rats. MATERIALS AND METHODS: In this experimental study, 28 adult Wistar rats were randomly divided into control (C), royal jelly (R), diabetic (D) and RJ-treated diabetic (D+R) groups...
August 2016: International Journal of Reproductive Biomedicine (Yazd, Iran)
https://www.readbyqxmd.com/read/27664731/royal-jelly-an-ancient-remedy-with-remarkable-antibacterial-properties
#13
REVIEW
Filippo Fratini, Giovanni Cilia, Simone Mancini, Antonio Felicioli
Royal Jelly (RJ), a honeybee hypopharyngeal gland secretion of young nurse and an exclusive nourishment for bee queen, has been used since ancient times for care and human health and it is still very important in traditional and folkloristic medicine, especially in Asia within the apitherapy. Recently, RJ and its protein and lipid components have been subjected to several investigations on their antimicrobial activity due to extensive traditional uses and for a future application in medicine. Antimicrobial activities of crude Royal Jelly, Royalisin, 10-hydroxy-2-decenoic acid, Jelleines, Major Royal Jelly Proteins against different bacteria have been reported...
November 2016: Microbiological Research
https://www.readbyqxmd.com/read/27602318/improvement-in-serum-biochemical-alterations-and-oxidative-stress-of-liver-and-pancreas-following-use-of-royal-jelly-in-streptozotocin-induced-diabetic-rats
#14
Elham Ghanbari, Vahid Nejati, Mozafar Khazaei
OBJECTIVE: This study aimed to evaluate the effects of royal jelly (RJ) on serum biochemical alterations and oxidative stress status in liver and pancreas of streptozotocin (STZ)- induced diabetic rats. MATERIALS AND METHODS: In this experimental study, thirty two male Wistar rats were divided into the following four groups (n=8/group): i. Control (C), ii. Diabetic (D), iii. Royal jelly (R), and iv. Royal jelly-treated diabetic (D/R) groups. Diabetes was induced by single intraperitoneal (IP) injection of STZ (60 mg/kg)...
2016: Cell Journal
https://www.readbyqxmd.com/read/27568457/royal-jelly-may-improve-the-metabolism-of-glucose-and-redox-state-of-ovine-oocytes-matured-in%C3%A2-vitro-and-embryonic-development-following-in%C3%A2-vitro-fertilization
#15
Mahbobeh Eshtiyaghi, Hamid Deldar, Zarbakht Ansari Pirsaraei, Bahram Shohreh
The aim of this study was to investigate the effect of different concentrations of royal jelly (RJ) on in vitro maturation (IVM), fertilization, cleavage, blastocyst rates, glutathione (GSH) content in ovine oocyte, mRNA abundance of antioxidant enzymes in both oocyte and cumulus, and glucose metabolism-related genes in cumulus cells. In vitro maturation of oocyte was performed in the presence of control (RJ0), 2.5 (RJ2.5), 5 (RJ5), and 10 (RJ10) mg/mL of RJ. Nuclear status, intracellular GSH content in oocytes, and mRNA abundance of selected genes were evaluated following 24 hours of IVM...
July 25, 2016: Theriogenology
https://www.readbyqxmd.com/read/27525943/amino-acid-composition-of-royal-jelly-harvested-at-different-times-after-larval-transfer
#16
H Jie, P M Li, G J Zhao, X L Feng, D J Zeng, C L Zhang, M Y Lei, M Yu, Q Chen
The amino acids in royal jelly (RJ) have a wide range of pharmacological and health-promoting functions in humans. Multiple studies on the amino acid quality and composition in RJ have investigated RJ harvested at 72 h after larval transfer. In contrast, the concentration of amino acids in RJ harvested before 72 h remains unknown. In this study, the concentration of free amino acids (FAAs) and total amino acids (TAAs) in RJ harvested at 13 time points between 24 and 72 h after transfer of ten Apis mellifera colonies were measured...
2016: Genetics and Molecular Research: GMR
https://www.readbyqxmd.com/read/27517116/proteomic-analysis-reveals-the-molecular-underpinnings-of-mandibular-gland-development-and-lipid-metabolism-in-two-lines-of-honeybees-apis-mellifera-ligustica
#17
Xinmei Huo, Bin Wu, Mao Feng, Bin Han, Yu Fang, Yue Hao, Lifeng Meng, Abebe Jenberie Wubie, Pei Fan, Han Hu, Yuping Qi, Jianke Li
The mandibular glands (MGs) of honeybee workers are vital for the secretion of lipids, for both larval nutrition and pheromones. However, knowledge of how the proteome controls MG development and functionality at the different physiological stages of worker bees is still lacking. We characterized and compared the proteome across different ages of MGs in Italian bees (ITBs) and Royal Jelly (RJ) bees (RJBs), the latter being a line bred for increasing RJ yield, originating from the ITB. All 2000 proteins that were shared by differently aged MGs in both bee lines (>4000 proteins identified in all) were strongly enriched in metabolizing protein, nucleic acid, small molecule, and lipid functional groups...
September 2, 2016: Journal of Proteome Research
https://www.readbyqxmd.com/read/27511354/apitherapy-products-enhance-the-recovery-of-ccl4-induced-hepatic-damages-in-rats
#18
Özlem Saral, Oktay Yildiz, Rezzan Aliyazicioğlu, Esin Yuluğ, Sinan Canpolat, Ferhat Öztürk, Sevgi Kolayli
BACKGROUND/AIM: Our objective was to identify the antioxidant properties of honeybee products from Turkey, chestnut honey, pollen, propolis, and royal jelly, and their hepatoprotective activity against CCl4-induced hepatic damage in rats. MATERIALS AND METHODS: Animals were fed with honeybee products for 7 days following CCl4 injection. Development of liver damage and oxidative stress were monitored by measuring the activities of the enzymes alanine transaminase, aspartate transaminase, malondialdehyde, superoxide dismutase, and catalase...
2016: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/27504161/effect-of-processed-honey-and-royal-jelly-on-cancer-related-fatigue-a-double-blind-randomized-clinical-trial
#19
Bahram Mofid, Hossein Rezaeizadeh, Abdulkarim Termos, Afshin Rakhsha, Ahmad Rezazadeh Mafi, Taiebeh Taheripanah, Mehran Mirabzadeh Ardakani, Seyed Mohammad Esmaeil Taghavi, Seyyed Alireza Moravveji, Amir Shahram Yousefi Kashi
BACKGROUND: Cancer-related fatigue (CRF) is experienced by 50% to 90% of cancer patients and can severely affect their quality of life and functional capacity. Several randomized trials have recommended various ways to alleviate the symptoms of CRF with or without recourse to medications. OBJECTIVE: The aim of this study is to evaluate the effectiveness of processed honey and royal jelly on the symptoms of CRF in cancer patients who are undergoing hormone therapy, chemotherapy, chemo-radiation, or radiotherapy...
June 2016: Electronic Physician
https://www.readbyqxmd.com/read/27496854/crosstalk-between-e2f1-and-c-myc-mediates-hepato-protective-effect-of-royal-jelly-on-taxol-induced-damages
#20
H Malekinejad, M Fani, S Kh Shafiee-Roodbari, F Delkhosh-Kasmaie, A Rezaei-Golmisheh
Previous histopathological studies have shown the hepatotoxicity of paclitaxel (TXL). However, there is little known about the molecular pathway(s) of TXL-induced hepatotoxicity. Therefore, this study aimed to uncover the role of two transcription factors in the TXL-induced hepatotoxicity. Moreover, the hepato-protective effect of royal jelly (RJ) on TXL-induced toxicity was investigated. Wistar rats were divided into control and test groups. The test groups along with TXL received various doses of RJ (0, 50, 100 and 150 mg/kg, body weight)...
August 5, 2016: Human & Experimental Toxicology
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