Hyunbin Cho, Jiwon Kim, Sukyung Kim, Hye-In Jeong, Mijeong Kwon, Hyun Mi Kim, Ji Sun Shim, Kyunga Kim, Jihyun Baek, Yechan Kyung, Suk-Joo Choi, Soo-Young Oh, Jaewoong Bae, Hong-Hee Won, Jihyun Kim, Kangmo Ahn
PURPOSE: We aimed to investigate the mediating factors between maternal anxiety and the development of food allergy (FA) in children until 2 years from birth. METHODS: In this longitudinal cohort of 122 mother-child dyads from pregnancy to 24 months of age, we regularly surveyed maternal psychological states, infant feeding data, and allergic symptoms and collected stool samples at 6 months of age for microbiome analysis. Considering the temporal order of data collection, we investigated serial mediating effects and indirect effects among maternal anxiety, dietary diversity (DD), gut microbial diversity, and FA using structural equation modeling...
March 2024: Allergy, Asthma & Immunology Research