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https://www.readbyqxmd.com/read/28209582/noninvasive-evaluation-of-cbf-and-perfusion-delay-of-moyamoya-disease-using-arterial-spin-labeling-mri-with-multiple-postlabeling-delays-comparison-with-15-o-gas-pet-and-dsc-mri
#1
S Hara, Y Tanaka, Y Ueda, S Hayashi, M Inaji, K Ishiwata, K Ishii, T Maehara, T Nariai
BACKGROUND AND PURPOSE: Arterial spin-labeling MR imaging with multiple postlabeling delays has a potential to evaluate various hemodynamic parameters. To clarify whether arterial spin-labeling MR imaging can identify CBF and perfusion delay in patients with Moyamoya disease, we compared arterial spin-labeling, DSC, and (15)O-gas PET in terms of their ability to identify these parameters. MATERIALS AND METHODS: Eighteen patients with Moyamoya disease (5 men, 13 women; ages, 21-55 years) were retrospectively analyzed...
February 16, 2017: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/28204602/measuring-cerebral-blood-flow-in-moyamoya-angiopathy-by-quantitative-magnetic-resonance-angiography-noninvasive-optimal-vessel-analysis
#2
Nadia Khan, Robert M Lober, Lauren Ostergren, Jacob Petralia, Teresa Bell-Stephens, Ramon Navarro, Abdullah Feroze, Gary K Steinberg
No abstract text is available yet for this article.
February 14, 2017: Neurosurgery
https://www.readbyqxmd.com/read/28202831/-development-of-intracerebral-hemorrhage-and-subarachnoid-hemorrhage-shortly-after-cerebral-infarction-onset-in-an-adult-patient-with-moyamoya-disease
#3
Jun Yoshida, Yoshitaka Kubo, Kenji Yoshida, Kohei Chida, Masakazu Kobayashi, Kuniaki Ogasawara
Here we describe the case of a patient with moyamoya disease who developed cerebral infarction followed shortly by subarachnoid hemorrhage and intracerebral hemorrhage. A 50-year-old woman presenting with sudden and transient weakness of the left lower limb was transferred to a local hospital. Magnetic resonance imaging(MRI)revealed cerebral infarction in the corpus callosum and in the bilateral frontal lobes induced by moyamoya disease. Pyramidal tract was not affected. The patient was treated with an anti-platelet agent(ozagrel sodium 160mg/day)and did not undergo intentional antihypertensive therapy...
February 2017: No Shinkei Geka. Neurological Surgery
https://www.readbyqxmd.com/read/28191623/the-ivy-sign-on-fluid-attenuated-inversion-recovery-images-related-to-single-photon-emission-computed-tomography-cerebral-blood-flow-in-moyamoya-disease-a-case-report
#4
Fumihiro Matano, Yasuo Murai, Asami Kubota, Takayuki Mizunari, Shiro Kobayashi, Akio Morita
BACKGROUND: Moyamoya disease is an idiopathic progressive cerebrovascular steno-occlusive disorder characterized by the formation of numerous collaterals called moyamoya vessels. Accurate evaluation of vascular status and CBF is needed for prompt treatment to prevent ischemic and/or hemorrhagic events. The pathogenesis of the ivy sign on fluid attenuated inversion recovery (FLAIR) images of moyamoya disease patients is unclear. We report a moyamoya disease case wherein the ivy sign changed in relation to SPECT-measured CBF during progression and following treatment...
January 17, 2017: Turkish Neurosurgery
https://www.readbyqxmd.com/read/28183578/a-case-of-central-diabetes-insipidus-after-ketamine-infusion-during-an-external-to-internal-carotid-artery-bypass
#5
Sharib Gaffar, Jonathan P Eskander, Burton D Beakley, Brian P McClure, Peter Amenta, Nakeisha Pierre
STUDY OBJECTIVE: We report the first teenage case of ketamine-induced transient central diabetes insipidus. CASE SUMMARY: The patient was an 18-year-old woman with moyamoya disease undergoing an external carotid to internal carotid bypass and given a low-dose ketamine infusion. After approximately 2 hours in the supine position, with 0.5 Minimum Alveolar Concentration (MAC) of sevoflurane, a propofol infusion at 50 μg/kg/min, a remifentanil infusion at 0.5 μg/kg/min, and a ketamine infusion at a dose of 10 μg/kg/min, this patient had an excessive urine output...
February 2017: Journal of Clinical Anesthesia
https://www.readbyqxmd.com/read/28176861/integrated-analysis-of-lncrna-mrna-co-expression-profiles-in-patients-with-moyamoya-disease
#6
Wen Wang, Faliang Gao, Zheng Zhao, Haoyuan Wang, Lu Zhang, Dong Zhang, Yan Zhang, Qing Lan, Jiangfei Wang, Jizong Zhao
Moyamoya disease (MMD) is an idiopathic disease associated with recurrent stroke. However, the pathogenesis of MMD remains unknown. Therefore, we performed long noncoding RNA (lncRNA) and messenger RNA (mRNA) expression profiles in blood samples from MMD patients (N = 15) and healthy controls (N = 10). A total of 880 differentially expressed lncRNAs (3649 probes) and 2624 differentially expressed mRNAs (2880 probes) were obtained from the microarrays of MMD patients and healthy controls (P < 0...
February 8, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28175916/synergistic-interactions-between-direct-and-indirect-bypasses-in-combined-procedures-the-significance-of-indirect-bypasses-in-moyamoya-disease
#7
Haruto Uchino, Jae-Hoon Kim, Noriyuki Fujima, Ken Kazumata, Masaki Ito, Naoki Nakayama, Satoshi Kuroda, Kiyohiro Houkin
No abstract text is available yet for this article.
February 1, 2017: Neurosurgery
https://www.readbyqxmd.com/read/28175446/198%C3%A2-effectiveness-of-surgical-revascularization-for-stroke-prevention-in-pediatric-patients-with-sickle-cell-disease-and-moyamoya-syndrome
#8
Wuyang Yang, Jose Luis Porras, Risheng Xu, Tomas Garzon-Muvdi, Justin M Caplan, Geoffrey P Colby, Alexander Lewis Coon, Rafael J Tamargo, Judy Huang, Edward Sanghoon Ahn
No abstract text is available yet for this article.
August 1, 2016: Neurosurgery
https://www.readbyqxmd.com/read/28168990/clinical-assessment-of-cerebral-hemodynamics-in-moyamoya-disease-via-multiple-inversion-time-arterial-spin-labeling-and-dynamic-susceptibility-contrast-magnetic-resonance-imaging-a-comparative-study
#9
Peng-Gang Qiao, Cong Han, Zhi-Wei Zuo, Yi-Tuo Wang, Josef Pfeuffer, Lian Duan, Tianyi Qian, Gong-Jie Li
BACKGROUND AND PURPOSE: For Moyamoya disease (MMD) patients, accurate hemodynamic assessment is critical for treatment selection and efficacy assessment. This study aims to investigate the clinical value of mTI-ASL in assessing the cerebral hemodynamics of MMD patients before and after revascularization, relative to DSC-MRI. MATERIALS AND METHODS: Forty-one MMD patients underwent mTI-ASL and DSC-MRI during blood perfusion. Quantitative parameters for the bilateral supply vessels of middle and anterior cerebral arteries, including DSC-TTP, DSC-CBF, ASL-BAT, and ASL-CBF were measured...
February 3, 2017: Journal of Neuroradiology. Journal de Neuroradiologie
https://www.readbyqxmd.com/read/28159458/relationship-between-the-change-of-language-symptoms-and-the-change-of-regional-cerebral-blood-flow-in-the-recovery-process-of-two-children-with-acquired-aphasia
#10
Junko Kozuka, Akira Uno, Hiroshi Matsuda, Yoshiya Toyoshima, Shin-Ichiro Hamano
OBJECTIVE: This study aimed to investigate the relationship between the change of language symptoms and the change of regional cerebral blood flow (rCBF) in the recovery process of two children with acquired aphasia caused by infarctions from Moyamoya disease with an onset age of 8years. METHODS: We compared the results for the Standard Language Test of Aphasia (SLTA) with rCBF changes in 7 language regions in the left hemisphere and their homologous regions in the right hemisphere at 4 time points from 3weeks for up to 5years after the onset of aphasia, while controlling for the effect of age...
January 31, 2017: Brain & Development
https://www.readbyqxmd.com/read/28157751/inherited-and-uncommon-causes-of-stroke
#11
Jennifer Juhl Majersik
PURPOSE OF REVIEW: This article is a practical guide to identifying uncommon causes of stroke and offers guidance for evaluation and management, even when large controlled trials are lacking in these rarer forms of stroke. RECENT FINDINGS: Fabry disease causes early-onset stroke, particularly of the vertebrobasilar system; enzyme replacement therapy should be considered in affected patients. Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), often misdiagnosed as multiple sclerosis, causes migraines, early-onset lacunar strokes, and dementia...
February 2017: Continuum: Lifelong Learning in Neurology
https://www.readbyqxmd.com/read/28153617/the-susceptibility-pathogenesis-of-the-moyamoya-disease
#12
Juntao Hu, Jie Luo, Qianxue Chen
Moyamoya disease (MMD) is a cerebrovascular disease characterized by progressive stenosis of the intracranial internal carotid arteries and their proximal branches. Epidemiologically, MMD is more prevalent in east Asia than any region worldwide, which have been estimated at 0.94 per 100 000 in Japanese and 0.43 per 100,000 in Chinese.However, the etiology of this rare disease remains unknown. Regarding biomarkers of moyamoya disease, moyamoya disease is characterized by an increased expression of angiogenic factors and pro-inflammatory molecules such as vascular endothelial growth factors and matrix metalloproteinase-9, which may partly explain its clinical manifestations of the pathologic angiogenesis, spontaneous hemorrhage, and higher incidence of cerebral hyperperfusion after revascularization surgery...
January 30, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28152266/bold-fmri-with-median-nerve-electrical-stimulation-predict-hemodynamic-improvement-after-revascularization-in-patients-with-moyamoya-disease
#13
Peng-Gang Qiao, Cong Han, Tianyi Qian, Gong-Jie Li, Hong Yin
PURPOSE: To assess the severity of cerebral hemodynamic impairment and hemodynamic improvements, after revascularization in moyamoya disease (MMD) by means of blood-oxygen-level dependent functional magnetic resonance imaging (BOLD-fMRI). MATERIALS AND METHODS: BOLD-fMRI with median nerve electrical stimulation based on echo planar imaging was performed in 73 volunteers with MMD and 15 healthy volunteers using a 3.0 Tesla MRI scanner. Twenty-four MMD patients were reexamined after encephaloduroarteriosynangiosis...
February 2, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/28132922/clinical-features-surgical-treatment-and-long-term-outcome-in-elderly-patients-with-moyamoya-disease
#14
Peicong Ge, Qian Zhang, Xun Ye, Xingju Liu, Xiaofeng Deng, Rong Wang, Yan Zhang, Dong Zhang, Jizong Zhao
OBJECTIVE: To elucidate the clinical features, surgical treatment, and long-term outcome in elderly patients with moyamoya disease (MMD). METHODS: We retrospectively reviewed 87 elderly patients with MMD at Beijing Tiantan Hospital. Clinical features, radiologic findings, and outcomes were analyzed. RESULTS: The mean age at diagnosis was 54.0±3.7 years, Familial occurrence was 2.3%. Underlying vascular risk factors was 74.7%. Infarction was most common symptom in elderly MMD (40...
January 26, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28109863/disruption-of-cortical-arterial-network-is-associated-with-the-severity-of-transient-neurological-events-after-direct-bypass-surgery-in-adult-moyamoya-disease
#15
Yusuke Egashira, Keita Yamauchi, Yukiko Enomoto, Noriyuki Nakayama, Shinichi Yoshimura, Toru Iwama
OBJECTIVE: Transient neurological events (TNEs) frequently occur after revascularization in adult moyamoya disease (MMD). In the present study, we hypothesized that cortical arterial network disruption may be associated with TNE severity following bypass surgery. METHODS: This retrospective study included 76 hemispheres in 45 consecutive adult MMD patients who underwent direct revascularization surgery at our institution. We classified cortical arterial network disruption grade (NDG) into the following four categories based on angiography: NDG 0, > 90% of suprasylvian cortical branches of the middle cerebral artery demonstrated anterograde filling; NDG 1, 50% to 90%; NDG 2, < 50%; NDG 3, none...
January 18, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28109734/clinical-characteristics-and-natural-history-of-quasi-moyamoya-disease
#16
Meng Zhao, Zhiqin Lin, Xiaofeng Deng, Qian Zhang, Dong Zhang, Yan Zhang, Rong Wang, Shuo Wang, Zhongli Jiang, Hao Wang, Jizong Zhao
BACKGROUND: Quasi-moyamoya disease (quasi-MMD) is a rare cerebrovascular disease and its clinical features and natural history remain unclear. The aim of the study is to describe the clinical characteristics and the natural histories of this disease, with analysis of the risk factors for future cerebrovascular events. METHODS: We identified 64 patients with quasi-MMD from 693 moyamoya vasculopathy patients referred to our hospital between 2011 and 2015. Demographic data, associated disorders, clinical manifestation, angiographic findings, natural history, and risk factors for cerebrovascular events were analyzed...
January 18, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/28104642/evaluation-of-encephaloduroarteriosynangiosis-efficacy-using-probabilistic-independent-component-analysis-applied-to-dynamic-susceptibility-contrast-perfusion-mri
#17
A N Laiwalla, F Kurth, K Leu, R Liou, J Pamplona, Y C Ooi, N Salamon, B M Ellingson, N R Gonzalez
BACKGROUND AND PURPOSE: Indirect cerebral revascularization has been successfully used for treatment in Moyamoya disease and symptomatic intracranial atherosclerosis. While angiographic neovascularization has been demonstrated after surgery, measurements of local tissue perfusion are scarce and may not reflect the reported successful clinical outcomes. We investigated probabilistic independent component analysis and conventional perfusion parameters from DSC-MR imaging to measure postsurgical changes in tissue perfusion...
January 19, 2017: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/28097429/early-and-noninvasive-evaluation-using-superficial-temporal-artery-duplex-ultrasonography-after-indirect-bypass-for-adult-ischemic-moyamoya-disease
#18
Sayaka Ogawa, Hiroshi Abe, Toshiro Katsuta, Kenji Fukuda, Toshiyasu Ogata, Koichi Miki, Tooru Inoue
BACKGROUND: The validity of indirect bypass for adult patients with moyamoya disease is still debatable. Some patients are poor responders to indirect bypass, and additive intervention is occasionally required in these cases. Therefore, it is necessary to evaluate the development of collateral circulation as early as possible postoperatively. METHODS: Fifteen adult patients (>17 years old) with moyamoya disease (22 affected sides) who underwent encephalo-duro-arterio-synangiosis (EDAS) at Fukuoka University Hospital from April 2008 to August 2014 were included...
March 2017: Acta Neurochirurgica
https://www.readbyqxmd.com/read/28093343/moyamoya-and-inflammation
#19
Juan C Mejia-Munne, Jason A Ellis, Neil A Feldstein, Philip M Meyers, Edward S Connolly
BACKGROUND: Over fifty years have elapsed since Moyamoya was initially described; however, the disease etiology remains unknown. Although certain genetic loci and immunological characteristics are associated with Moyamoya, this does not fully explain its pathophysiology. An association with inflammatory disease has been postulated but not rigorously explored. We sought to examine the epidemiological association of Moyamoya and inflammatory diseases by analyzing data from a large administrative database...
January 13, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28072843/chemokine-ligand-5-ccl5-derived-from-endothelial-colony-forming-cells-ecfcs-mediates-recruitment-of-smooth-muscle-progenitor-cells-spcs-toward-critical-vascular-locations-in-moyamoya-disease
#20
Ji Hoon Phi, Naoko Suzuki, Youn Joo Moon, Ae Kyung Park, Kyu-Chang Wang, Ji Yeoun Lee, Seung-Ah Choi, Sangjoon Chong, Reizo Shirane, Seung-Ki Kim
The etiology and pathogenesis of moyamoya disease (MMD) are still obscure. Previous studies indicated that angiogenic chemokines may play an important role in the pathogenesis of the disease. Recently, it was discovered that peripheral blood-derived endothelial colony-forming cells (ECFCs) and smooth muscle progenitor cells (SPCs) have defective functions in MMD patients. Therefore, the interaction of ECFCs and SPCs, the precursors of two crucial cellular components of vascular walls, with some paracrine molecules is an intriguing subject...
2017: PloS One
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