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https://www.readbyqxmd.com/read/29143295/posterior-circulation-involvement-in-pediatric-and-adult-patients-with-moyamoya-disease-a-single-center-experience-in-574-patients
#1
Meng Zhao, Dong Zhang, Shuo Wang, Yan Zhang, Rong Wang, Xiaofeng Deng, Jizong Zhao
The importance of the posterior cerebral artery (PCA) involvement in moyamoya disease has been highlighted in recent years. However, few studies compared the impact of PCA lesions in moyamoya disease between pediatric and adult patients. We conducted this study to summarize the clinical features of moyamoya patients with PCA lesions and describe the difference between pediatric and adult patients. We reviewed the records of 696 consecutive moyamoya vasculopathy patients from 2009 to 2015. The Suzuki and the Miyamoto stages were used to evaluate the steno-occlusive lesions of the anterior and posterior arteries...
November 15, 2017: Acta Neurologica Belgica
https://www.readbyqxmd.com/read/29138020/moyamoya-syndrome-in-a-pediatric-patient-with-congenital-human-immunodeficiency-virus-type-1-infection-resulting-in-intracranial-hemorrhage
#2
Junko Yamanaka, Ikuma Nozaki, Mizue Tanaka, Hideko Uryuu, Noriko Sato, Takeji Matsushita, Hiroyuki Shichino
In the era of Antiretroviral Therapy (ART) in which human immunodeficiency virus type 1 (HIV-1) infection affected children can expect a better prognosis, the importance of careful follow up of pediatric HIV-1 cases for neurological complications has been growing. We present a case of hemorrhagic Moyamoya syndrome in a child with congenital HIV-1 infection. A 10-year-old girl was referred to our hospital for the treatment of Pneumocystis Jirovecii Pneumonia (PCP: Pneumocystis pneumonia). Her HIV-1 control was poor and Moyamoya syndrome was found during the opportunistic infection screening at admission...
November 11, 2017: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
https://www.readbyqxmd.com/read/29128331/risk-factors-for-epilepsy-recurrence-after-revascularization-in-pediatric-patients-with-moyamoya-disease
#3
Yonggang Ma, Meng Zhao, Qian Zhang, Xingju Liu, Dong Zhang, Shuo Wang, Yan Zhang, Maogui Li, Jizong Zhao
OBJECTIVE: We aimed to explore the risk factors of seizure recurrence and the optimal surgical procedure for epileptic pediatric patients with moyamoya disease (MMD). METHODS: We reviewed 696 consecutive patients with MMD admitted to our hospital from 2009 to 2015. Pediatric patients with MMD who had seizures before revascularization were identified. We summarized the characteristics of seizures in pediatric patients with MMD and analyzed the predictive factors of recurrent seizure events...
November 8, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/29112977/initial-clinical-experience-with-dual-layer-detector-spectral-ct-in-patients-with-acute-intracerebral-haemorrhage-a-single-centre-pilot-study
#4
Soo Buem Cho, Hye Jin Baek, Kyeong Hwa Ryu, Jin Il Moon, Bo Hwa Choi, Sung Eun Park, Kyungsoo Bae, Kyung Nyeo Jeon, Dong Wook Kim
PURPOSE: The purpose of this study was to investigate the clinical feasibility of spectral analyses using dual-layer detector spectral computed tomography (CT) in acute intracerebral haemorrhage (ICH). MATERIAL AND METHODS: We retrospectively reviewed patients with acute ICH who underwent CT angiography on a dual-layer detector spectral CT scanner. A spectral data analysis was performed to detect contrast enhancement in or adjacent to acute ICH by using spectral image reconstructions including monoenergetic (MonoE), virtual noncontrast (VNC), and iodine overlay fusion images...
2017: PloS One
https://www.readbyqxmd.com/read/29107436/the-collateral-circulation-in-moyamoya-disease-a-single-center-experience-in-140-pediatric-patients
#5
Meng Zhao, Dong Zhang, Shuo Wang, Yan Zhang, Xiaofeng Deng, Jizong Zhao
BACKGROUND: The patterns and clinical significance of the presence of collaterals in moyamoya disease has not been elucidated thoroughly. We aimed to summarize the clinical features of collaterals in pediatric moyamoya disease. BASIC PROCEDURES: We reviewed consecutive pediatric patients with moyamoya vasculopathy who were admitted to our hospital from 2009 to 2015. Only pediatric moyamoya patients with digital subtraction angiography examinations were included in this study...
September 14, 2017: Pediatric Neurology
https://www.readbyqxmd.com/read/29103427/neuroinflammation-in-ischemic-pediatric-stroke
#6
Maja Steinlin
Over the last decades, the importance of inflammatory processes in pediatric stroke have become increasingly evident. Ischemia launches a cascade of events: activation and inhibition of inflammation by a large network of cytokines, adhesion and small molecules, protease, and chemokines. There are major differences in the neonatal brain compared to adult brain, but developmental trajectories of the process during childhood are not yet well known. In neonatal stroke ischemia is the leading pathophysiology, but infectious and inflammatory processes have a significant input into the course and degree of tissue damage...
August 2017: Seminars in Pediatric Neurology
https://www.readbyqxmd.com/read/29102749/surgical-revascularization-for-children-with-moyamoya-disease-a-new-modification-to-the-pial-synangiosis
#7
Chuan Chen, Hui Wang, Bo Hou, Lun Luo, Ying Guo
OBJECTIVE: To summarize the therapeutic efficacy of modified pial synangiosis in children with moyamoya disease and our experience with this method. METHOD: A retrospective study was conducted to analyze the clinical efficacy of modified pial synangiosis in children with moyamoya disease who were treated between October 2002 and August 2015 in our center. The clinical characteristics of these rare cases were summarized, and the surgical efficacy was assessed based on long-term follow-up results...
November 1, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29102581/variant-angina-leading-to-cardiac-arrest%C3%A2-in-a-patient-with-moyamoya-disease
#8
Masahiko Noguchi, Kotaro Obunai, Kuniyasu Saigusa, Hiroyuki Watanabe
No abstract text is available yet for this article.
October 25, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29077743/proposing-a-validated-clinical-app-predicting-hospitalization-cost-for-extracranial-intracranial-bypass-surgery
#9
Hai Sun, Piyush Kalakoti, Kanika Sharma, Jai Deep Thakur, Rimal H Dossani, Devi Prasad Patra, Kevin Phan, Hesam Akbarian-Tefaghi, Frank Farokhi, Christina Notarianni, Bharat Guthikonda, Anil Nanda
OBJECT: United States healthcare reforms are focused on curtailing rising expenditures. In neurosurgical domain, limited or no data exists identifying potential modifiable targets associated with high-hospitalization cost for cerebrovascular procedures such as extracranial-intracranial (ECIC) bypass. Our study objective was to develop a predictive model of initial cost for patients undergoing bypass surgery. METHODS: In an observational cohort study, we analyzed patients registered in the Nationwide Inpatient Sample (2002-2011) that underwent ECIC bypass...
2017: PloS One
https://www.readbyqxmd.com/read/29076784/direct-versus-indirect-revascularization-in-the-treatment-of-moyamoya-disease
#10
Seong-Eun Park, Ju-Seong Kim, Eun Kyung Park, Kyu-Won Shim, Dong-Seok Kim
OBJECTIVE For patients with moyamoya disease (MMD), surgical intervention is usually required because of progressive occlusion of the internal carotid artery. The indirect bypass method has been widely accepted as the treatment of choice in pediatric patients. However, in adult patients with MMD, the most effective treatment method remains a matter of debate. Here, the authors compared the clinical outcomes from MMD patients treated with either extracranial-intracranial arterial bypass (EIAB; 43 hemispheres) or modified encephaloduroarteriosynangiosis (mEDAS; 75 hemispheres) to investigate whether mEDAS is an effective surgical method for treating adults with symptomatic MMD...
October 27, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29061453/prevention-of-the-rerupture-of-collateral-artery-aneurysms-on-the-ventricular-wall-by-early-surgical-revascularization-in-moyamoya-disease-report-of-two-cases-and-review-of-the-literature
#11
Fumiaki Kanamori, Syuntaro Takasu, Shinji Ota, Yukio Seki
BACKGROUND: Collateral artery aneurysms are a source of intracranial hemorrhage in moyamoya disease. Several reports have shown that surgical revascularization leads to the obliteration of collateral artery aneurysms. However, its effect on the prevention of rebleeding has not been established, and the optimal timing of the operation remains unclear. The purpose of the present study is to evaluate the effects of surgical revascularization and to investigate the optimal operation timing in patients with moyamoya disease who have ruptured collateral artery aneurysms on the ventricular wall...
October 20, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29056445/characteristics-of-cerebral-hemodynamics-assessed-by-ct-perfusion-in-moyamoya-disease
#12
Ayaka Sasagawa, Takeshi Mikami, Toru Hirano, Yukinori Akiyama, Nobuhiro Mikuni
Due to the recent development of multidetector row computed tomography (CT), hemodynamic parameters can now be conveniently obtained with CT perfusion. The purpose of this study is to characterize the hemodynamic parameters of CT perfusion in moyamoya disease, and to discuss the differences in collateral circulation between moyamoya disease and atherosclerotic disease. A total of 16 hemispheric sides of 15 patients with moyamoya disease and 10 hemispheric sides of 9 patients with atherosclerotic disease who underwent bypass surgery were included...
October 19, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/29055274/comparative-study-of-4d-cta-and-dsa-for-vascular-assessment-in-moyamoya-disease
#13
Bing Tian, Yuanliang Jiang, Qinqin Kang, Bing Xu, Ri Liu, Qi Liu, Jianping Lu
PURPOSE: To evaluate the vascular stenosis and collateral circulation in moyamoya disease using 4D CTA. METHODS: Two neuroradiologists evaluated 4D CTA and DSA for 101 moyamoya patients. The performance of 4D CTA relative to DSA was determined using consistency checks (kappa values, 95% CI) and correlation analysis. RESULTS: The kappa values were 0.714 (modified Suzuki score), 0.846 (Houkin score), 0.594 (basicranial moyamoya vessels), 0.435 (posterior circulation collaterals) and 0...
October 12, 2017: Clinical Imaging
https://www.readbyqxmd.com/read/29053072/quantitative-assessment-of-changes-in-hemodynamics-of-the-internal-carotid-artery-after-bypass-surgery-for-moyamoya-disease
#14
Fengping Zhu, Yi Qian, Bin Xu, Yuxiang Gu, Kaavya Karunanithi, Wei Zhu, Liang Chen, Ying Mao, Michael K Morgan
OBJECTIVE Although intracranial vessel remodeling has been observed in moyamoya disease, concerns remain regarding the effect of bypass surgery on hemodynamic changes within the internal carotid artery (ICA). The authors aimed to quantify the surgical effect of bypass surgery on bilateral ICAs in moyamoya disease and to estimate pressure drop (PD) along the length of the ICA to predict surgical outcomes. METHODS Records of patients who underwent bypass surgery for treatment of moyamoya disease and in whom flow rates were obtained pre- and postsurgery by quantitative MR angiography were retrospectively reviewed...
October 20, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29046137/magnetic-resonance-imaging-mri-and-digital-subtraction-angiography-investigation-of-childhood-moyamoya-disease
#15
Peiji Song, Jing Qin, Han Lun, Penggang Qiao, Anming Xie, Gongjie Li
Because digital subtraction angiography (DSA) is not an ideal angiographic examination for moyamoya disease in the pediatric population, magnetic resonance angiography (MRA) provides a noninvasive contrast-free angiographic examination; whereas magnetic resonance imaging (MRI) provides superior spatial resolution and soft-tissue contrast for lesion assessment. Ninety patients with moyamoya disease were examined by MRI and DSA to assess the distribution of lesions and their diagnostic agreement between modalities...
November 2017: Journal of Child Neurology
https://www.readbyqxmd.com/read/29030229/elevation-of-proenkephalin-143-183-in-cerebrospinal-fluid-in-moyamoya-disease
#16
Kinya Yokoyama, Mikio Maruwaka, Kazuhiro Yoshikawa, Yoshio Araki, Sho Okamoto, Masaki Sumitomo, Akino Kawamura, Yusuke Sakamoto, Kenzo Shimizu, Takashi Izumi, Toshihiko Wakabayashi
BACKGROUND: In moyamoya disease (MMD), the causes of differences in clinical features between children and adults and of the dramatic temporal changes in moyamoya vessels are poorly understood. We previously discovered elevated levels of m/z 4588 and m/z 4473 peptides in cerebrospinal fluid (CSF) in MMD patients. This study examined the amino acid sequences of these peptides and quantified in specimens. METHODS: The m/z 4588 and m/z 4473 peptides in CSF from MMD patients were purified and concentrated by high-performance liquid chromatography and ultrafiltration...
October 10, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29028653/adams-oliver-syndrome-with-moyamoya-disease-for-cerebral-revascularisation-surgery
#17
(no author information available yet)
No abstract text is available yet for this article.
October 12, 2017: Journal of Neurosurgical Anesthesiology
https://www.readbyqxmd.com/read/28991692/altered-expression-of-circular-rnas-in-moyamoya-disease
#18
Meng Zhao, Faliang Gao, Dong Zhang, Shuo Wang, Yan Zhang, Rong Wang, Jizong Zhao
Moyamoya disease (MMD) is the most common pediatric cerebrovascular disease in Eastern Asian countries but the etiology is not well understood. Circular RNAs (circRNAs) have been implicated in various biological processes, but their role in the development of MMD remains unclear. To address this issue, we carried out a comparative circRNA microarray analysis of blood samples obtained from patients with MMD and healthy subjects and identified 146 circRNAs that were differentially expressed between the two groups...
October 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28989169/moyamoya-disease-in-an-18-month-old-female-caucasian-complicated-by-cerebral-hyperperfusion-syndrome-following-indirect-revascularization
#19
James Murchison, John M Wilson, Coby Ray, Jessica Ginsberg, Laszlo Nagy
BACKGROUND Cerebral hyperperfusion syndrome is a rare complication of indirect revascularization due to moyamoya disease, but has not been reported previously in the pediatric population. We present a case of an 18-month-old girl with moyamoya disease that was treated with bilateral pial synangiosis and had complications consistent with cerebral hyperperfusion syndrome. This case report discusses the pathophysiological mechanisms involved in cerebral hyperperfusion in moyamoya syndrome. CASE REPORT An 18-month-old female Caucasian presented with seizures and weakness of the left side...
October 9, 2017: American Journal of Case Reports
https://www.readbyqxmd.com/read/28987832/postoperative-cerebral-ischemia-due-to-hypotension-in-a-moyamoya-patient-with-autonomic-dysfunction-a-case-report
#20
Toshio Machida, Yoshinori Higuchi, Shigeki Nakano, Satoshi Ishige, Junichiro Shimada, Koichi Honma
BACKGROUND: Hypotension is a significant risk factor for the development of ischemic complication following revascularization surgery for moyamoya disease (MMD). However, it is currently unknown whether autonomic dysfunction also plays a role. CASE DESCRIPTION: Here we report a case of MMD in which hypotension due to autonomic dysfunction caused postoperative cerebral ischemia. A 30-year-old female patient with MMD had a history of transient right hemiparesis following laughter...
October 4, 2017: World Neurosurgery
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