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Allison Werner-Lin, Lori Zaspel, Mae Carlson, Rebecca Mueller, Sarah A Walser, Ria Desai, Barbara A Bernhardt
Clinical genome and exome sequencing (CGES) may identify variants leading to targeted management of existing conditions. Yet, CGES often fails to identify pathogenic diagnostic variants and introduces uncertainties by detecting variants of uncertain significance (VUS) and secondary findings. This study investigated how families understand findings and adjust their perspectives on CGES. As part of NIH's Clinical Sequencing Exploratory Research Consortium, children were recruited from clinics at the Children's Hospital of Pennsylvania (CHOP) and offered exome sequencing...
March 2018: American Journal of Medical Genetics. Part A
Jeffrey Laurence
No abstract text is available yet for this article.
February 13, 2018: AIDS Patient Care and STDs
Kristin J Homan, Tracy L Tylka
Although researchers and clinicians recognize the importance of positive body image for women's well-being, development of theoretical frameworks for understanding positive body image has not kept pace with research documenting its many benefits. The present study proposed and tested a comprehensive model linking gratitude, contingent self-worth, social comparison, body appreciation, and intuitive eating. Path analysis indicated that this model fit the data for a sample of college and online community women (N = 263)...
February 8, 2018: Body Image
Jamie Dunaev, Charlotte H Markey, Paula M Brochu
Internalized weight bias and body dissatisfaction are associated with a number of negative psychological and physical health outcomes. The current study examined the effectiveness of body-focused gratitude, through a short writing exercise, as a strategy to reduce internalized weight bias and improve body image. Young adults (Mage = 22.71, SD = 2.08, 51.2% female) were randomly assigned to either a body gratitude condition (n = 185) or a control condition (n = 184). Results indicated that participants in the gratitude condition reported significantly lower weight bias internalization and significantly more favorable appearance evaluation and greater body satisfaction when compared to the control condition...
February 7, 2018: Body Image
Pamela Adelstein
A space can be sacred, providing those who inhabit a particular space with sense of transcendence-being connected to something greater than oneself. The sacredness may be inherent in the space, as for a religious institution or a serene place outdoors. Alternatively, a space may be made sacred by the people within it and events that occur there. As medical providers, we have the opportunity to create sacred space in our examination rooms and with our patient interactions. This sacred space can be healing to our patients and can bring us providers opportunities for increased connection, joy, and gratitude in our daily work...
2018: Global Advances in Health and Medicine: Improving Healthcare Outcomes Worldwide
Charlotta Pisinger, Torben Jørgensen, Ulla Toft
The aim of this paper was to investigate if a multifactorial approach may be used to explain why national smoking rates have levelled off in Denmark after 60 years of decline. 
Methods: Seven hypothetical explanations for stagnation in smoking rate were explored. A period of five years with a declining smoking prevalence (2007-2011) was compared with four years of stalled smoking prevalence (2012-2015). We used individual and national level information sources, mostly cross-sectional data that were collected repeatedly, including large nationally representative surveys, sales stat-istics, nation-wide news and smoking cessation databases and legal information, among others...
February 2018: Danish Medical Journal
John G Gunderson
Ueli Kramer has assembled an eclectic and original set of articles on mechanisms of change in the treatment of borderline personality disorder. They largely focus on patient variables. Several authors make the point that developmentally based variables may have more predictive power than symptom-based variables. Several other articles illustrate that changes occur early in treatments and studying their mechanisms is a promising approach that could have longer term significance. These articles document the variety of research methodologies that can be used to study mechanisms of change and the potential clinical significance of doing this...
January 2018: Journal of Personality Disorders
Ann R Beck, Heidi Verticchio
Purpose: The purpose of this study is to explore the effects of a daily mindfulness practice and 2 types of journaling on participants' development of self-compassion. Method: This was a between-groups design. All participants in a graduate counseling course engaged in a short daily mindfulness practice at the beginning of every class. Participants were randomly assigned to a counseling journal or a gratitude journal group. Participants were to write in their journals 2 to 5 times a week for the duration of the class...
January 30, 2018: American Journal of Speech-language Pathology
Christian Molerin
No abstract text is available yet for this article.
November 4, 2017: Practical Radiation Oncology
Swati Sharma, Kamlesh Singh
Researchers have consistently advocated positive associations between religion and well-being. The present research takes a step forward and explores potential mechanisms behind the same. The mediating role of a surprisingly neglected mechanism, positive virtues, specifically gratitude, forgiveness and altruism, is studied through a quantitative study on a sample of 220 adult respondents residing in Delhi NCR. The participants adhered to one of the six major religions present in India. Mediational analysis revealed that gratitude mediated the relationship between religiosity, spirituality and well-being via two pathways of forgiveness and altruism...
January 20, 2018: Journal of Religion and Health
Erin C McCanlies, Ja Kook Gu, Michael E Andrew, John M Violanti
BACKGROUND: Police officers in the New Orleans geographic area faced a number of challenges following Hurricane Katrina. AIM: This cross-sectional study examined the effect of social support, gratitude, resilience and satisfaction with life on symptoms of depression. METHOD: A total of 86 male and 30 female police officers from Louisiana participated in this study. Ordinary least-square (OLS) regression mediation analysis was used to estimate direct and indirect effects between social support, gratitude, resilience, satisfaction with life and symptoms of depression...
February 2018: International Journal of Social Psychiatry
Vivek Lal, Manoj K Goyal
History helps us to become better students, judge wisely, understand change, and most importantly, it tells us who we are. It helps us to understand what happened, why it happened and what its ramifications are. Winston Churchill once said: "Study history, study history. In history lie all the secrets of statecraft." Here, we take this opportunity to pay our gratitude to our esteemed teachers who worked relentlessly for uplifting of the department of Neurology, PGIMER, Chandigarh; and, narrate chronicles of all those people who made this department reach the heights where it stands today...
January 2018: Neurology India
Elizabeth K McClain
No abstract text is available yet for this article.
January 1, 2018: Journal of the American Osteopathic Association
Tanja V E Kral
The percentage of children in the United States with obesity has more than tripled since the 1970s. Despite considerable work in this area, there has been limited success in the long-term treatment and prevention of childhood obesity. In order for intervention approaches to be successful, it will be crucial to study individual variation and the underlying mechanisms that impact human ingestive behavior. Research in my laboratory has focused on identifying behavioral phenotypes for childhood obesity which may be used to develop targeted intervention approaches that are tailored to a child's individual predisposition...
January 4, 2018: Physiology & Behavior
Hannelore Hendrickx, Phillip N Blondeel, Hanna Van Parys, Nathalie A Roche, Patrick C Peeters, Hubert F Vermeersch, Xavier Rogiers, Kristiane Van Lierde, Gilbert M D Lemmens
Increasing evidence points to good functional, aesthetic, and psychosocial outcomes after face transplantation. However, research investigating how patients and their families subjectively experience the transplantation process is lacking thus far. This study aims to investigate the personal experiences of a blind face transplant patient and his partner. In-depth interviews exploring different experiences were conducted with both partners separately 20 months after face transplantation. The interviews were analyzed using interpretative phenomenological analysis...
January 4, 2018: Journal of Craniofacial Surgery
Annika M Kisch, Anna Forsberg, Isabell Fridh, Matilda Almgren, Martina Lundmark, Charlotte Lovén, Anne Flodén, Madeleine Nilsson, Veronika Karlsson, Annette Lennerling
BACKGROUND: Studies on living donors from the donors' perspective show that the donation process involves both positive and negative feelings involving vulnerability. Qualitative studies of living kidney, liver, and allogeneic hematopoietic stem cell donors have not previously been merged in the same analysis. Therefore, our aim was to synthesize current knowledge of these donors' experiences in order to deepen understanding of the meaning of being a living donor for the purpose of saving or extending someone's life...
January 2, 2018: Transplantation
Stefan Salzmann, Frank Euteneuer, Jana Strahler, Johannes A C Laferton, Urs M Nater, Winfried Rief
BACKGROUND: A new approach of psychological interventions prior to stress aiming to optimize expectations may have beneficial effects on a person's health status by reducing physiological stress. The purpose of this experiment was to determine whether a brief psychological intervention designed to optimize personal control expectations prior to acute stress would affect perceived and biological stress responsiveness in comparison to two more established interventions (fostering gratitude or distraction) in a healthy sample...
December 21, 2017: Psychoneuroendocrinology
Christina N Massey, Emily H Feig, Laura Duque-Serrano, Jeff C Huffman
Positive psychological characteristics such as optimism, positive affect, gratitude, and related constructs may play an important role in health. In patients with type 2 diabetes (T2D), positive psychological constructs have been associated with superior medical outcomes, including better glucose control and lower mortality rates. The beneficial effects of positive psychological states in T2D are most likely mediated through health behaviors such as increased physical activity and adherence to a healthier diet...
October 2017: Current Research in Diabetes & Obesity Journal
Emily L Zale, Catherine Pierre-Louis, Eric A Macklin, Eric Riklin, Ana-Maria Vranceanu
The neurofibromatoses (NF) are incurable genetic disorders that can cause nerve sheath tumors, chronic pain, and disfiguration. Patients with NF report lower quality of life and greater distress, and may benefit from programs that promote resiliency. To test effects of an 8-week mind-body program (Relaxation Response Resiliency Program for NF [3RP-NF]) on resiliency, using data derived from a larger randomized controlled trial of the 3RP-NF versus attention placebo control (Vranceanu et al. in Neurology 87:806-814, 2016)...
December 23, 2017: Journal of Neuro-oncology
Shirley Yen, Megan L Ranney, Katherine M Tezanos, Adam Chuong, Christopher W Kahler, Joel B Solomon, Anthony Spirito
"Skills to Enhance Positivity" (STEP) is a two-part positive affect program designed to decrease recurrent suicidal behavior in adolescents hospitalized due to suicide risk. Here, we describe the initial pilot phase in which the intervention was developed and modified based on a sample of 20 adolescent participants, aged 12 to 18 years old ( Mage = 15.9, SD = 1.5). STEP consisted of an in-person phase (four sessions) and a remote delivery phase (text messaging and phone calls). The inpatient sessions focused on psychoeducation of positive affect, mindfulness meditation, gratitude, and savoring...
December 1, 2017: Behavior Modification
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