keyword
https://read.qxmd.com/read/38595418/comparative-study-on-efficacy-of-empagliflozin-versus-sitagliptin-as-an-add-on-therapy-to-metformin-in-type-2-diabetic-patients
#21
JOURNAL ARTICLE
Harsh Salankar, Sonali Rode, C Arjun, Rajeeta Joseph, Gourav B Deshmane, Radhika P Vijayan
INTRODUCTION: More than 28.7 million individuals throughout the globe suffer from diabetes mellitus, with an estimated 11 percent of the population living with the condition in India. Changes in lifestyle and a variety of treatment plans are used in management. Metformin is a key drug for glycemic control, both when used alone and in combination. Our research compares the effectiveness of glycemic control achieved by empagliflozin plus sitagliptin. METHODS: This study took place from November 2022 to April 2023 at the tertiary care hospital...
February 2024: Journal of Pharmacy & Bioallied Sciences
https://read.qxmd.com/read/38594634/utilize-multi-metabolic-parameters-as-determinants-for-prediction-of-skeletal-muscle-mass-quality-in-elderly-type2-diabetic-chinese-patients
#22
JOURNAL ARTICLE
Huiling Chen, Jingjing Lou, Meiyuan Dong, Xintao Liu, Shijie Yan, Song Wen, Ligang Zhou, Xingdang Liu, Xinlu Yuan
BACKGROUND: Sarcopenia, an age-related disorder characterized by loss of skeletal muscle mass and function, is recently recognized as a complication in elderly patients with type 2 diabetes mellitus (T2DM). Skeletal muscles play a crucial role in glycemic metabolism, utilizing around 80% of blood glucose. Accordingly, we aimed to explore the relationship between glucose metabolism and muscle mass in T2DM. METHODS: We employed the AWGS 2019 criteria for diagnosing low muscle mass and 1999 World Health Organization (WHO) diabetes diagnostic standards...
April 9, 2024: BMC Geriatrics
https://read.qxmd.com/read/38592202/vitamin-d-a-new-therapeutic-target-in-the-management-of-type-2-diabetes-patients
#23
JOURNAL ARTICLE
Oana Albai, Adina Braha, Bogdan Timar, Ioana Golu, Romulus Timar
Background : Vitamin D is a fat-soluble vitamin that prevents cardiovascular diseases and diabetes mellitus (DM). The present research aimed to study the impact of 25-hydroxyvitamin D (25(OH)D) level on the health status of patients with type 2 DM (T2DM) hospitalized in the "Pius Brînzeu" Emergency Clinical County University Hospital in Timisoara, Romania. Methods : The study retrospectively included 160 patients with T2DM who were clinically and biologically evaluated during hospitalization. Results : 13...
February 28, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38590111/comparison-of-stress-hyperglycemia-ratio-and-glycemic-gap-on-acute-ich-in-hospital-outcomes
#24
JOURNAL ARTICLE
Jia Zhang, Qian Zhang, Hongqiu Gu, Qi Zhou, Zixiao Li, Xingquan Zhao
OBJECTIVE: To compare the effect of different indicators on stress-induced hyperglycemia for predicting in-hospital outcomes of acute intracerebral hemorrhage. METHODS: Using data from the Chinese Stroke Center Alliance database, which is a national, multicenter, prospective, and consecutive program. Stress-induced hyperglycemia was described as glycemic gap (GG, defined as fasting blood glucose [FBG] minus estimated average blood glucose) and stress hyperglycemia ratio (SHR, defined as FBG-to-estimated average blood glucose ratio [SHR 1] or FBG-to-HbA1c ratio [SHR 2])...
April 8, 2024: Annals of Clinical and Translational Neurology
https://read.qxmd.com/read/38589985/association-between-hypotension-during-pancreatectomy-and-development-of-postoperative-diabetes
#25
JOURNAL ARTICLE
Seoil Moon, Mirang Lee, Jun Suh Lee, Jooyeop Lee, Tae Jung Oh, Myoung-Jin Jang, Yoo-Seok Yoon, Youngmin Han, Wooil Kwon, Jin-Young Jang, Hye Seung Jung
CONTEXT: With advancements in long-term survival after pancreatectomy, post-pancreatectomy diabetes has become a concern, and the risk factors are not established yet. Pancreatic islets are susceptible to ischemic damage, though there is a lack of clinical evidence regarding glycemic deterioration. OBJECTIVE: To investigate association between hypotension during pancreatectomy and development of post-pancreatectomy diabetes. DESIGN: In this retrospective, longitudinal cohort study, we enrolled patients without diabetes who underwent distal pancreatectomy or pancreaticoduodenectomy between January 2005 and December 2018, from two referral hospitals in Korea...
April 9, 2024: Journal of Clinical Endocrinology and Metabolism
https://read.qxmd.com/read/38587726/differences-in-glycemic-control-for-inpatients-with-type-1-diabetes-on-insulin-pump-versus-subcutaneous-insulin-therapy
#26
JOURNAL ARTICLE
Yuting Ye, Bernardo A Acevedo-Mendez, Stephanie Izard, Alyson K Myers
BACKGROUND: Inpatient use of insulin pump therapy has been increasing due to greater availability of this technology, however there is a paucity of research that investigates glycemic control of inpatient insulin pump users. OBJECTIVE: To compare the glycemic control of hospitalized patients with type 1 diabetes (T1D) who used insulin pump vs. multiple daily injections (MDI). DESIGN: Retrospective chart review. PARTICIPANTS: Patients with T1D who were hospitalized between January 1, 2017, and December 31, 2019, in an academic medical center in the New York metropolitan area...
April 8, 2024: Journal of General Internal Medicine
https://read.qxmd.com/read/38586620/health-literacy-self-efficacy-and-glycemic-control-in-patients-with-diabetes-type-2-in-a-greek-population
#27
JOURNAL ARTICLE
Panagiotis Panagiotidis, Athena Kalokairinou, Chara Tzavara, Anastasia Michailidou, Venetia-Sofia Velonaki
Aim  To investigate the relationship between health literacy (HL), self-efficacy (SE), and achievement of treatment goals in patients with type 2 diabetes mellitus (T2DM). Method The cross-sectional study was conducted with a random sample of patients with T2DM attending the diabetology clinic and the Home Care department of the General Hospital of Drama, Greece. They completed two questionnaires: the short form of the European Health Literacy Survey Questionnaire (HLS-EU-Q16) to measure HL and the Diabetes Management Self-Efficacy Scale (DMSES) for people with T2DM to measure SE...
March 2024: Curēus
https://read.qxmd.com/read/38586073/relationship-between-electrolytes-and-glycated-hemoglobin-among-diabetic-patients-with-poor-adherence-to-antidiabetic-medications-a-cross-sectional-study
#28
JOURNAL ARTICLE
Francis Lengeiya, Scholastica Mathenge, Patroba Ojola
INTRODUCTION: type 2 Diabetes mellitus is a chronic metabolic disease with devastating effects on patients and results in numerous healthcare challenges in terms of its management and the cost burden among the affected. Successful management involves maintaining optimal glycemic control to prevent complications, with adherence to antidiabetic medications playing a crucial role in achieving this objective. Additionally, maintaining a healthy electrolyte balance is key for overall well-being and physiological function...
2024: Pan African Medical Journal
https://read.qxmd.com/read/38585321/effects-of-glycemic-variability-in-critically-ill-patients-with-coronavirus-disease-2019-a-retrospective-observational-study
#29
JOURNAL ARTICLE
Emerson Boschi, Gilberto Friedman, Rafael B Moraes
AIM AND BACKGROUND: Hyperglycemia is considered an adaptive metabolic manifestation of stress and is associated with poor outcomes. Herein, we analyzed the association between glycemic variability (GV) and hospital mortality in patients with coronavirus disease 2019 (COVID-19) admitted to the intensive care unit (ICU), and the association between GV and mechanical ventilation (MV), ICU stay, length of hospital stays, renal replacement therapy (RRT), hypoglycemia, nosocomial infections, insulin use, and corticosteroid class...
April 2024: Indian Journal of Critical Care Medicine
https://read.qxmd.com/read/38571859/prevalence-of-metabolic-syndrome-and-its-risk-factors-influence-on-microvascular-complications-in-patients-with-type-1-and-type-2-diabetes-mellitus
#30
JOURNAL ARTICLE
Asad Riaz, Shoaib Asghar, Salman Shahid, Haider Tanvir, Muhammad Hamza Ejaz, Mamuna Akram
BACKGROUND: Diabetes mellitus (DM) long-term macrovascular and microvascular complications pose significant health risks and increase mortality. In DM patients, metabolic syndrome (MetSy) either precedes or coexists with the condition. Central obesity, poor glycemic control, hypertension, elevated triglycerides (TG), and low high-density lipoproteins (HDL-C) are the components of MetSy. The purpose of this study is to investigate related diabetic microvascular complications in type 1 DM (T1DM) by comparing them with type 2 DM (T2DM), determine potential risk factors, and estimate prevalence based on the diagnosis of MetSy...
March 2024: Curēus
https://read.qxmd.com/read/38563225/influence-of-disease-course-and-comprehensive-management-on-blood-glucose-level-in-children-and-adolescents-with-type%C3%A2-2-diabetes-mellitus
#31
JOURNAL ARTICLE
Xiaozhi Wu, Rui Wang, Jiahui Chen, Guoshuang Feng, Xinyu Wang, Robin N Bai, Xuejun Liang, Binyan Cao, Chunxiu Gong, Wenjing Li, Yanmei Sang, Xumei Wang, Di Wu
AIMS/INTRODUCTION: The aim of the present study was to evaluate the status of glycemic control, and assess the effects of the disease course and comprehensive management measures on the blood glucose level in children and adolescents with type 2 diabetes mellitus. MATERIALS AND METHODS: The study collected the clinical data of type 2 diabetes patients in Beijing Children's Hospital from January 2015 to September 2020. Patients were grouped based on the disease course to compare their glycated hemoglobin (HbA1c) level, islet β-cell function, insulin resistance and comprehensive management measures...
April 2, 2024: Journal of Diabetes Investigation
https://read.qxmd.com/read/38559691/current-barriers-to-initiating-insulin-therapy-in-individuals-with-type-2-diabetes
#32
REVIEW
Alba Galdón Sanz-Pastor, Alicia Justel Enríquez, Ana Sánchez Bao, Francisco Javier Ampudia-Blasco
Insulin is an essential drug in the treatment of diabetes, often necessary for managing hyperglycemia in type 2 diabetes mellitus (T2DM). It should be considered in cases of severe hyperglycemia requiring hospitalization, after the failure of other treatments, in advanced chronic kidney disease, liver cirrhosis, post-transplant diabetes, or during pregnancy. Moreover, in specific patient subgroups, early initiation of insulin is crucial for hyperglycemia control and prevention of chronic complications. Clinical guidelines recommend initiating insulin when other treatments fail, although there are barriers that may delay its initiation...
2024: Frontiers in Endocrinology
https://read.qxmd.com/read/38559690/assessment-of-the-severity-of-diabetic-polyneuropathy-aids-in-predicting-the-risk-of-developing-diabetic-complications-in-patients-with-untreated-diabetes
#33
JOURNAL ARTICLE
Shuji Horinouchi, Takahisa Deguchi, Miki Mukai, Ayako Ijuin, Yudai Kawamoto, Yoshihiko Nishio
This study aimed to determine the efficacy of assessing the severity of diabetic polyneuropathy (DPN) in patients with untreated diabetes. Seventy-two patients with untreated type 2 diabetes who were hospitalized for glycemic control were enrolled and divided into the following two groups: patients who had no prior diagnosis and patients who were unattended or had discontinued treatment. Electrophysiological criteria consistent with Baba's classification were used to diagnose and assess the severity of DPN...
2024: Frontiers in Endocrinology
https://read.qxmd.com/read/38556511/type-1-diabetes-management-in-the-hospital-setting
#34
JOURNAL ARTICLE
Andrea Granados, Adriana Carrillo Iregui
The incidence of diabetes in children and adolescents has increased during the past decades, with a 1.9% increase per year in type 1 diabetes mellitus (T1DM). Patients with diabetes have a greater risk of hospitalizations compared with those without diabetes. Clear evidence has emerged in the past decade that supports appropriate glycemic control in the hospital setting to improve clinical outcomes and reduce the risk of hospital complications and mortality. Determining the appropriate insulin regimen in patients with T1DM in the hospital depends on the clinical status, type of outpatient insulin regimen (multiple daily injections versus pump therapy), glycemic control before admission, nutritional status, procedures, and enteral versus parenteral nutrition...
April 1, 2024: Pediatrics in Review
https://read.qxmd.com/read/38553738/coronary-inflammation-based-on-pericoronary-adipose-tissue-attenuation-in-type-2-diabetic-mellitus-effect-of-diabetes-management
#35
JOURNAL ARTICLE
Yuankang Liu, Lisong Dai, Yue Dong, Cong Ma, Panpan Cheng, Cuiping Jiang, Hongli Liao, Ying Li, Xiang Wang, Xiangyang Xu
BACKGROUND: Coronary inflammation plays crucial role in type 2 diabetes mellitus (T2DM) induced cardiovascular complications. Both glucose-lowering drug interventions (GLDIS) and glycemic control (GC) status potentially correlate coronary inflammation, as indicated by changes in pericoronary adipose tissue (PCAT) attenuation, and thus influence cardiovascular risk. This study evaluated the impact of GLDIS and GC status on PCAT attenuation in T2DM patients. METHODS: This retrospective study collected clinical data and coronary computed tomography angiography (CCTA) images of 1,342 patients, including 547 T2DM patients and 795 non-T2DM patients in two tertiary hospitals...
March 29, 2024: Cardiovascular Diabetology
https://read.qxmd.com/read/38549700/nutritional-status-in-patients-with-tuberculosis-and-diabetes-mellitus-a-comparative-observational-study
#36
JOURNAL ARTICLE
Divya Girishbhai Patel, Tejaswini Baral, Shilia Jacob Kurian, Pravachana Malakapogu, Kavitha Saravu, Sonal Sekhar Miraj
BACKGROUND: India has been estimated to have 14 % of malnourished population and a high TB incidence burden with a 26.9 lakh cases. Malnutrition and diabetes mellitus are major risk factors for tuberculosis infection. Malnutrition in patients with both tuberculosis and diabetes (TB-DM) population worsens the disease severity, treatment outcomes and increases morbidity and mortality risk. OBJECTIVE: To assess the nutritional status in patients with TB-DM compared with patients with TB and DM alone...
May 2024: Journal of Clinical Tuberculosis and Other Mycobacterial Diseases
https://read.qxmd.com/read/38544988/the-effectiveness-of-the-trans-theoretical-model-in-managing-adult-obese-and-overweight-individuals
#37
JOURNAL ARTICLE
Cigdem Gereklioglu, Kenan Topal, Hatice Velipasaoglu, Huseyin Aksoy
BACKGROUND & OBJECTIVE: The prevalence of obesity is gradually increasing in our country and worldwide. Being obese and overweight are risk factors for chronic diseases. Obesity has a multifactorial etiology, so treatment should involve lifestyle changes, psychological strategies, pharmacologic treatment, and bariatric surgery. The present study aimed to investigate the effectiveness of the trans-theoretical stages of change (TTM SOC) model in managing adult obese and overweight patients...
2024: Pakistan Journal of Medical Sciences Quarterly
https://read.qxmd.com/read/38532941/central-pancreatectomy-balancing-between-the-favorable-functional-results-and-the-increased-associated-morbidity
#38
Dimitrios Symeonidis, Ismini Paraskeva, Athina A Samara, Labrini Kissa, Alexandros Valaroutsos, Eleana Petsa, Konstantinos Tepetes
Introduction  Central pancreatectomy (CP) represents an organ-preserving type of pancreatic resection. The procedure has been associated with improved long-term functional results, but increased postoperative morbidity rates, compared with the more radical resection types. The purpose of the present study was to present the outcomes of three consecutive CPs performed in our department. Materials and Methods  Between January 2021 and January 2022, three patients (A, B, and C) were submitted to a CP in our department...
January 2024: Surgery Journal
https://read.qxmd.com/read/38525377/sglt2-inhibitors-beyond-glycemic-control
#39
JOURNAL ARTICLE
Irtiza Hasan, Tasnuva Rashid, Vishal Jaikaransingh, Charles Heilig, Emaad M Abdel-Rahman, Alaa S Awad
Multiple randomized controlled trials have extensively examined the therapeutic effectiveness of sodium-glucose cotransporter 2 (SGLT2) inhibitors, ushering in a transformative approach to treating individuals with type 2 diabetes mellitus (DM). Notably, emerging reports have drawn attention to the potential positive impacts of SGLT2 inhibitors in nondiabetic patients. In an effort to delve into this phenomenon, a comprehensive systematic literature review spanning PubMed (NLM), Medline (Ovid), and Cochrane Library, covering publications from 2000 to 2024 was undertaken...
March 2024: Journal of Clinical & Translational Endocrinology
https://read.qxmd.com/read/38525088/glycemic-control-in-patients-living-with-hiv-initiated-on-integrase-inhibitor-based-three-drug-antiretroviral-therapy
#40
JOURNAL ARTICLE
Anthony Gerber, Briann Fischetti, Olga Popova, Maria Longo
Background: The increased risk of cardio-metabolic disorders associated with people living with human immunodeficiency virus (HIV) is of growing importance. Given the broad adoption of integrase strand-transfer inhibitor (INSTI)-based antiretroviral therapy (ART) as first-line therapy for HIV, additional data are needed regarding the metabolic effects of these regimens. Objective: The purpose of this study is to assess glycemic control in patients started on INSTI-based 3-drug regimens over a 2-year period...
April 2024: Journal of Pharmacy Technology: JPT: Official Publication of the Association of Pharmacy Technicians
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