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https://www.readbyqxmd.com/read/29216940/-study-on-risk-factor-of-central-venous-catheter-infection-in-icu-1-160-patients-report
#1
Ming Zhang, Yongqing Xu, Zhiming Jiang, Junying Qian, Zhonghui Zhang, Nannan Sun, Jian Xie, Tao Li
OBJECTIVE: To analyze the etiology and risk factors of central venous catheter (CVCs) infections, and to explore the prophylaxis and treatment for catheter-related infections. METHODS: A retrospective study was conducted. The patients with CVCs admitted to intensive care unit (ICU) of Qianfoshan Hospital Affiliated to Shandong University from January 2000 to December 2016 were enrolled. The gender, age, catheter data and microorganism culture results of all patients were collected...
December 2017: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
https://www.readbyqxmd.com/read/29032585/infection-surveillance-in-pediatric-hematopoietic-stem-cell-transplantation-recipients
#2
Daniela Caldas Teixeira, Lilian Martins Oliveira Diniz, Paulo Henrique Orlandi Mourão, Fabiana Maria Kakehashi, Antonio Vaz de Macedo, Helena Duani, Wanessa Trindade Clemente, Karla Emília de Sá Rodrigues, Roberta Maia de Castro Romanelli
OBJECTIVE: Describe the profile of reported Healthcare-Associated Infections (HAIs) in pediatric patients submitted to hematopoietic stem cell transplantation (HSCT) at a reference center. METHODS: Retrospective cohort of pediatric patients who were submitted to HSCT from 2008 to 2016. The criteria for HAI were based on those established by the National Healthcare Safety Network. Data were collected by active surveillance performed daily by professionals. This study was approved by the Institutional Research Ethics Committee...
October 15, 2017: European Journal of Haematology
https://www.readbyqxmd.com/read/28929959/-in-vitro-effect-of-vancomycin-and-daptomycin-on-biofilm-formation-of-coagulase-negative-staphylococci-strains
#3
Duygu Nilüfer Öcal, İştar Dolapçı, Zeynep Gençtürk, Alper Tekeli
Coagulase-negative staphylococci (CNS) are one of the primer agents of blood stream infections (BSI) and catheter-related bloodstream infections (CR-BSI) which are associated mostly with the usage of central venous catheters and, important causes of morbidity and mortality despite the usage of antibacterial and supportive treatment. It is important to determine the properties of these causative microorganisms in order to make appropriate treatment of such infections. The aims of our study were to evaluate the biofilm formation of coagulase negative staphylococci (CNS) which were causative agents of bloodstream (BSI) and catheter related bloodstream infections (CR-BSI), to determine the minimum inhibitory concentration (MIC) of planktonic forms and minimal biofilm eradication concentration (MBEC) of sessile forms for vancomycin and daptomycin and to evaluate the efficacy of these antibiotics in infections with biofilm-forming isolates in vitro...
July 2017: Mikrobiyoloji Bülteni
https://www.readbyqxmd.com/read/28743533/should-non-bacteraemic-patients-with-a-colonized-catheter-receive-antimicrobial-therapy
#4
V De Egea, M Guembe, A Rodríguez-Borlado, M J Pérez-Granda, C Sánchez-Carrillo, E Bouza
OBJECTIVES: The impact of antimicrobial therapy on the outcomes of patients with colonized catheters and no bacteraemia has not been assessed. This study assessed whether targeted antibiotic therapy is related to a poor outcome in patients with positive cultures of blood drawn through a non-tunnelled central venous catheter (CVC) and without concomitant bacteraemia. METHODS: This was a retrospective study involving adult patients with positive blood cultures drawn through a CVC and negative peripheral vein blood cultures...
September 2017: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/28259730/incidence-of-central-venous-catheter-hub-contamination
#5
Julie L Holroyd, Terrie Vasilopoulos, Mark J Rice, Kenneth H Rand, Brenda G Fahy
PURPOSE: To investigate microorganisms causing central venous catheter contamination and how this contamination differs across different catheter metrics. MATERIALS AND METHODS: After obtaining IRB approval and informed consent, 830 cultures were prospectively obtained from 45 ICU patients with central venous catheter or peripherally inserted central catheter. Bacterial colonies were identified by mass spectrometry. RESULTS: Bacterial contamination of central catheter hubs occurred 44% of the time in this study in the ICU setting...
June 2017: Journal of Critical Care
https://www.readbyqxmd.com/read/28191308/ralstonia-mannitolilytica-infections-in-an-oncologic-day-ward-description-of-a-cluster-among-high-risk-patients
#6
Claudia Lucarelli, Enea Gino Di Domenico, Luigi Toma, Domenico Bracco, Grazia Prignano, Maria Fortunati, Lorella Pelagalli, Fabrizio Ensoli, Patrizio Pezzotti, Aurora García-Fernández, Annalisa Pantosti, Loredana Ingrosso
BACKGROUND: Ralstonia spp, an environmental microorganism, has been occasionally associated with healthcare infections. The aim of this study was to investigate an outbreak caused by Ralstonia mannitolilytica in oncology patients. METHODS: Case definition: Oncology outpatients attending a day ward, with positive blood and/or central venous catheter (CVC) culture for Ralstonia spp from September 2013 - June 2014. We analysed medical records, procedures and environmental samples...
2017: Antimicrobial Resistance and Infection Control
https://www.readbyqxmd.com/read/28130997/antiseptic-barrier-cap-effective-in-reducing-central-line-associated-bloodstream-infections-a-systematic-review-and-meta-analysis
#7
REVIEW
Anne F Voor In 't Holt, Onno K Helder, Margreet C Vos, Laura Schafthuizen, Sandra Sülz, Agnes van den Hoogen, Erwin Ista
BACKGROUND: Microorganisms can intraluminally access a central venous catheter via the catheter hub. The catheter hub should be appropriately disinfected to prevent central line-associated bloodstream infections (CLABSIs). However, compliance with the time-consuming manual disinfection process is low. An alternative is the use of an antiseptic barrier cap, which cleans the catheter hub by continuous passive disinfection. OBJECTIVE: To compare the effects of antiseptic barrier cap use and manual disinfection on the incidence of CLABSIs...
April 2017: International Journal of Nursing Studies
https://www.readbyqxmd.com/read/28017547/a-systematic-review-of-waterborne-infections-from-nontuberculous-mycobacteria-in-health-care-facility-water-systems
#8
Trudy Li, Lydia S Abebe, Ryan Cronk, Jamie Bartram
Healthcare-acquired infections are an increasing problem for health care providers and policy makers. Water is an overlooked source of infectious microorganisms in health care facilities. Waterborne nontuberculous mycobacteria (NTM) are ubiquitous, and particularly problematic in health care facility water systems, and cause a variety of diseases. The purpose of this review is to assess health care associated NTM infections from health care facility water systems. We documented susceptible populations, modes of transmission, and the median attack rate (e...
December 19, 2016: International Journal of Hygiene and Environmental Health
https://www.readbyqxmd.com/read/27666952/risk-factors-for-central-line-associated-bloodstream-infection-in-pediatric-oncology-patients-with-a-totally-implantable-venous-access-port-a-cohort-study
#9
Michelle Ribeiro Viana Taveira, Luciana Santana Lima, Cláudia Corrêa de Araújo, Maria Júlia Gonçalves de Mello
BACKGROUND: Totally implantable venous access ports (TIVAPs) are used for prolonged central venous access, allowing the infusion of chemotherapy and other fluids and improving the quality of life of children with cancer. TIVAPs were developed to reduce the infection rates associated with central venous catheters; however, infectious events remain common and have not been fully investigated in pediatric oncology patients. PROCEDURE: A retrospective cohort was formed to investigate risk factors for central line-associated bloodstream infection (CLABSI) in pediatric cancer patients...
February 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/27615546/burn-associated-bloodstream-infections-in-pediatric-burn-patients-time-distribution-of-etiologic-agents
#10
İlker Devrim, Ahu Kara, Mine Düzgöl, Aytaç Karkıner, Nuri Bayram, Günyüz Temir, Arzu Şencan, Yelda Sorguç, Gamze Gülfidan, Münevver Hoşgör
BACKGROUND: Infections are the leading cause of morbidity and mortality in patients with burns in burn units. Bloodstream infections (BSIs) in patients with burns may result from burn wound infection, use of invasive devices such as central venous catheters, and translocation of the gastrointestinal flora. OBJECTIVE: In this study, we investigated the distribution and antimicrobial drug resistance of causative pathogens in children with burns and the durational changes of microorganisms in the distribution of BSIs in children...
February 2017: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/27423929/hemodialysis-catheter-related-infection-rates-risk-factors-and-pathogens
#11
Farida Sahli, Razika Feidjel, Rima Laalaoui
The main complication of central venous catheter (CVC) in hemodialysis is infection. Identifying CVC related infection (CVC-RI) risk factors and causative micro-organisms is important for setting prevention policies. There were no data regarding CVC-RI in hemodialysis in Algeria. To determine rates of CVC-RI in hemodialysis in Setif university hospital, risk factors and causative microorganisms, we conducted a prospective study from November 2014 to May 2015 involving patients with CVC in hemodialysis. Micro-organisms isolated from semi quantitative culture of CVC and blood culture were identified and tested for antibiotic susceptibility using the automated MicroScan system (DADE Behring, Sacramento, CA, USA)...
July 2017: Journal of Infection and Public Health
https://www.readbyqxmd.com/read/27422799/-incidence-of-catheter-related-infection-incidence-and-risk-factors-in-patients-on-total-parenteral-nutrition-in-a-third-level-hospital
#12
Miguel Parra-Flores, Luis Manuel Souza-Gallardo, Gabriel Adrián García-Correa, Sócrates Centellas-Hinojosa
BACKGROUND: Central venous catheters are devices used for therapeutic, diagnostic, and monitoring purposes. Complications associated with central venous catheter use include those related to their insertion, rupture and displacement of the catheter, occlusion, thrombosis, and infection. Of these the latter is important due to the high morbidity and mortality it causes in the patients, and total parenteral nutrition increases the risk. The aim of this study is determine the incidence and risk factors associated with catheter-related infection in patients on parenteral nutrition...
July 12, 2016: Cirugia y Cirujanos
https://www.readbyqxmd.com/read/26977277/candida-associated-bloodstream-infections-in-pediatric-hematology-patients-a-single-center-experience
#13
Dilek Gurlek Gokcebay, Nese Yarali, Pamir Isik, Cengiz Bayram, Aslinur Ozkaya-Parlakay, Abdurrahman Kara, Bahattin Tunc
BACKGROUND AND OBJECTIVES: Candida-associated bloodstream infections are frequent and potentially life-threatening conditions in hematology patients. The aim of this study is to evaluate the characteristics, risk factors, and outcome of Candida-associated bloodstream infections in children with hematological diseases. METHODS: The medical records of the patients with hematological diseases and hematopoietic stem cell transplantation (HSCT) recipients who were diagnosed as Candida-associated bloodstream infection between February 2010 and February 2014 were reviewed retrospectively...
2016: Mediterranean Journal of Hematology and Infectious Diseases
https://www.readbyqxmd.com/read/26958069/successfully-treated-infective-endocarditis-caused-by-methicillin-resistant-staphylococcus-aureus-in-extremely-low-birth-weight-infant
#14
Sehwa Jung, Kyung Uk Jeong, Jang Hoon Lee, Jo Won Jung, Moon Sung Park
Survival rates of preterm infants have improved in the past few decades, and central venous catheters play an important role in the intensive medical treatment of these neonates. Unfortunately, these indwelling catheters increase the risk of intracardiac thrombosis, and they provide a nidus for microorganisms during the course of septicemia. Herein, we report a case of persistent bacteremia due to methicillin-resistant Staphylococcus aureus in an extremely low birth weight (ELBW) infant, along with vegetation observed on an echocardiogram, the findings which are compatible with a diagnosis of endocarditis...
February 2016: Korean Journal of Pediatrics
https://www.readbyqxmd.com/read/26838274/assessment-of-central-venous-catheter-colonization-using-surveillance-culture-of-withdrawn-connectors-and-insertion-site-skin
#15
María Jesús Pérez-Granda, María Guembe, Raquel Cruces, José María Barrio, Emilio Bouza
BACKGROUND: Culture of catheter hubs and skin surrounding the catheter entry site has a negative predictive value for catheter tip colonization. However, manipulation of the hub for culture requires the hubs to be swabbed, introducing potential dislodging of biofilm and subsequent migration of microorganisms. Hubs are usually closed with needleless connectors (NCs), which are replaced regularly. Our objective was to evaluate whether culture of flushed withdrawn NCs is an alternative to hub culture when investigating central venous catheter colonization...
2016: Critical Care: the Official Journal of the Critical Care Forum
https://www.readbyqxmd.com/read/26596030/-systemic-inflammatory-response-on-nosocomial-bacteremia
#16
E A Gayfutdinov, V A Rudnov, V A Bagin
GOAL: study of special aspects in system inflammatory reaction caused by nosocomial bacteremia in dependence of the pathogen Gram-origin. The study included 85 patients with nosocomial bacteremia in ICU from 2010 till 2012. The main inclusion criteria was bacteria identification in blood, which was taken more than 48 hours from arrival to ICU within the appearance of system inflammatory response signs. Key options for clinical rating of system inflammatory response was dynamic of patients condition according APACHE II, SOFA, SAPS-III/PIRO, Pitt scales and its correlation with durations of mechanical ventilation, length of staying in ICU, total hospital period and outcome...
July 2015: Anesteziologiia i Reanimatologiia
https://www.readbyqxmd.com/read/26583299/device-associated-pneumonia-of-very-low-birth-weight-infants-in-polish-neonatal-intensive-care-units
#17
Jadwiga Wójkowska-Mach, T Allen Merritt, Maria Borszewska-Kornacka, Joanna Domańska, Ewa Gulczyńska, Marek Nowiczewski, Ewa Helwich, Agnieszka Kordek, Dorota Pawlik, Paweł Adamski
PURPOSE: Late-Onset Pneumonia (LO-PNEU) is still the most important complication associated with the hospitalization of infants with very low birth weight (<1501g). The purpose of this paper is to summarize the results of an ongoing surveillance program defining LO-PNEU as associated or not associated with respiratory support in the NICU and distribution of causative pathogens from the Polish Neonatology Surveillance Network (PNSN). MATERIALS AND METHODS: Surveillance of infections was conducted in the years 2009-2011 at six Polish NICUs...
March 2016: Advances in Medical Sciences
https://www.readbyqxmd.com/read/26462311/do-needle-free-connectors-prevent-catheter-related-bloodstream-infections-in-patients-receiving-hemodialysis-treatments-using-central-venous-catheters
#18
Lisa Micklos
The rate of central venous catheter (CVC) use for patients on hemodialysis in the United States has decreased in recent years, though the rate of hospitalizations due to infections has increased. Each time a CVC hub is accessed, there is potential for microorganisms to enter the lumen and initiate a bloodstream infection. Needle-free catheter connectors provide a mechanically closed space to preventfrequent manipulation of catheter hubs. The needle-free connector may be a valuable addition to incorporate into infection prevention policies for hemodialysis units...
July 2015: Nephrology Nursing Journal: Journal of the American Nephrology Nurses' Association
https://www.readbyqxmd.com/read/26455868/clinical-evaluation-of-a-chlorhexidine-intravascular-catheter-gel-dressing-on-short-term-central-venous-catheters
#19
Tarja J Karpanen, Anna L Casey, Tony Whitehouse, Peter Nightingale, Ira Das, Thomas S J Elliott
BACKGROUND: A major source of microbial colonization of short-term central venous catheters (CVC) is the patients' endogenous skin microorganisms located at the CVC insertion site. The aim of this study was to determine if a transparent film dressing incorporating a 2% (weight/weight) chlorhexidine gluconate (CHG) gel decreases CVC and insertion site microbial colonization compared with a nonantimicrobial dressing in adult patients in critical care. METHODS: On CVC removal, samples for microbiological investigation were taken from both the skin surrounding the CVC insertion site and also from sutures securing the CVC...
January 1, 2016: American Journal of Infection Control
https://www.readbyqxmd.com/read/26364857/trends-in-nosocomial-infections-and-multidrug-resistant-microorganisms-in-spanish-pediatric-intensive-care-units
#20
MULTICENTER STUDY
Iolanda Jordan Garcia, Elisabeth Esteban Torné, Amaya Bustinza Arriortua, Juan Carlos de Carlos Vicente, Patricia García Soler, José Andrés Concha Torre, José Carlos Flores González, Paula Madurga Revilla, Mercedes Palomar Martínez
INTRODUCTION: Nosocomial infections (NI) are a major healthcare problem. National surveillance systems enable data to be compared and to implement new measures to improve our practice. METHODS: A multicentre, prospective, descriptive and observational study was conducted using the data from surveillance system for nosocomial infections created in 2007 for Spanish pediatric intensive care units. Data were collected for one month, between 01 and 31 March, for every study year (2008-2012)...
May 2016: Enfermedades Infecciosas y Microbiología Clínica
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