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Microorganisms central venous catheters

Michelle Ribeiro Viana Taveira, Luciana Santana Lima, Cláudia Corrêa de Araújo, Maria Júlia Gonçalves de Mello
BACKGROUND: Totally implantable venous access ports (TIVAPs) are used for prolonged central venous access, allowing the infusion of chemotherapy and other fluids and improving the quality of life of children with cancer. TIVAPs were developed to reduce the infection rates associated with central venous catheters; however, infectious events remain common and have not been fully investigated in pediatric oncology patients. PROCEDURE: A retrospective cohort was formed to investigate risk factors for central line-associated bloodstream infection (CLABSI) in pediatric cancer patients...
September 26, 2016: Pediatric Blood & Cancer
İlker Devrim, Ahu Kara, Mine Düzgöl, Aytaç Karkıner, Nuri Bayram, Günyüz Temir, Arzu Şencan, Yelda Sorguç, Gamze Gülfidan, Münevver Hoşgör
BACKGROUND: Infections are the leading cause of morbidity and mortality in patients with burns in burn units. Bloodstream infections (BSIs) in patients with burns may result from burn wound infection, use of invasive devices such as central venous catheters, and translocation of the gastrointestinal flora. OBJECTIVE: In this study, we investigated the distribution and antimicrobial drug resistance of causative pathogens in children with burns and the durational changes of microorganisms in the distribution of BSIs in children...
September 8, 2016: Burns: Journal of the International Society for Burn Injuries
Farida Sahli, Razika Feidjel, Rima Laalaoui
The main complication of central venous catheter (CVC) in hemodialysis is infection. Identifying CVC related infection (CVC-RI) risk factors and causative micro-organisms is important for setting prevention policies. There were no data regarding CVC-RI in hemodialysis in Algeria. To determine rates of CVC-RI in hemodialysis in Setif university hospital, risk factors and causative microorganisms, we conducted a prospective study from November 2014 to May 2015 involving patients with CVC in hemodialysis. Micro-organisms isolated from semi quantitative culture of CVC and blood culture were identified and tested for antibiotic susceptibility using the automated MicroScan system (DADE Behring, Sacramento, CA, USA)...
July 13, 2016: Journal of Infection and Public Health
Miguel Parra-Flores, Luis Manuel Souza-Gallardo, Gabriel Adrián García-Correa, Sócrates Centellas-Hinojosa
BACKGROUND: Central venous catheters are devices used for therapeutic, diagnostic, and monitoring purposes. Complications associated with central venous catheter use include those related to their insertion, rupture and displacement of the catheter, occlusion, thrombosis, and infection. Of these the latter is important due to the high morbidity and mortality it causes in the patients, and total parenteral nutrition increases the risk. The aim of this study is determine the incidence and risk factors associated with catheter-related infection in patients on parenteral nutrition...
July 12, 2016: Cirugia y Cirujanos
Dilek Gurlek Gokcebay, Nese Yarali, Pamir Isik, Cengiz Bayram, Aslinur Ozkaya-Parlakay, Abdurrahman Kara, Bahattin Tunc
BACKGROUND AND OBJECTIVES: Candida-associated bloodstream infections are frequent and potentially life-threatening conditions in hematology patients. The aim of this study is to evaluate the characteristics, risk factors, and outcome of Candida-associated bloodstream infections in children with hematological diseases. METHODS: The medical records of the patients with hematological diseases and hematopoietic stem cell transplantation (HSCT) recipients who were diagnosed as Candida-associated bloodstream infection between February 2010 and February 2014 were reviewed retrospectively...
2016: Mediterranean Journal of Hematology and Infectious Diseases
Sehwa Jung, Kyung Uk Jeong, Jang Hoon Lee, Jo Won Jung, Moon Sung Park
Survival rates of preterm infants have improved in the past few decades, and central venous catheters play an important role in the intensive medical treatment of these neonates. Unfortunately, these indwelling catheters increase the risk of intracardiac thrombosis, and they provide a nidus for microorganisms during the course of septicemia. Herein, we report a case of persistent bacteremia due to methicillin-resistant Staphylococcus aureus in an extremely low birth weight (ELBW) infant, along with vegetation observed on an echocardiogram, the findings which are compatible with a diagnosis of endocarditis...
February 2016: Korean Journal of Pediatrics
María Jesús Pérez-Granda, María Guembe, Raquel Cruces, José María Barrio, Emilio Bouza
BACKGROUND: Culture of catheter hubs and skin surrounding the catheter entry site has a negative predictive value for catheter tip colonization. However, manipulation of the hub for culture requires the hubs to be swabbed, introducing potential dislodging of biofilm and subsequent migration of microorganisms. Hubs are usually closed with needleless connectors (NCs), which are replaced regularly. Our objective was to evaluate whether culture of flushed withdrawn NCs is an alternative to hub culture when investigating central venous catheter colonization...
2016: Critical Care: the Official Journal of the Critical Care Forum
E A Gayfutdinov, V A Rudnov, V A Bagin
GOAL: study of special aspects in system inflammatory reaction caused by nosocomial bacteremia in dependence of the pathogen Gram-origin. The study included 85 patients with nosocomial bacteremia in ICU from 2010 till 2012. The main inclusion criteria was bacteria identification in blood, which was taken more than 48 hours from arrival to ICU within the appearance of system inflammatory response signs. Key options for clinical rating of system inflammatory response was dynamic of patients condition according APACHE II, SOFA, SAPS-III/PIRO, Pitt scales and its correlation with durations of mechanical ventilation, length of staying in ICU, total hospital period and outcome...
July 2015: Anesteziologiia i Reanimatologiia
Jadwiga Wójkowska-Mach, T Allen Merritt, Maria Borszewska-Kornacka, Joanna Domańska, Ewa Gulczyńska, Marek Nowiczewski, Ewa Helwich, Agnieszka Kordek, Dorota Pawlik, Paweł Adamski
PURPOSE: Late-Onset Pneumonia (LO-PNEU) is still the most important complication associated with the hospitalization of infants with very low birth weight (<1501g). The purpose of this paper is to summarize the results of an ongoing surveillance program defining LO-PNEU as associated or not associated with respiratory support in the NICU and distribution of causative pathogens from the Polish Neonatology Surveillance Network (PNSN). MATERIALS AND METHODS: Surveillance of infections was conducted in the years 2009-2011 at six Polish NICUs...
March 2016: Advances in Medical Sciences
Lisa Micklos
The rate of central venous catheter (CVC) use for patients on hemodialysis in the United States has decreased in recent years, though the rate of hospitalizations due to infections has increased. Each time a CVC hub is accessed, there is potential for microorganisms to enter the lumen and initiate a bloodstream infection. Needle-free catheter connectors provide a mechanically closed space to preventfrequent manipulation of catheter hubs. The needle-free connector may be a valuable addition to incorporate into infection prevention policies for hemodialysis units...
July 2015: Nephrology Nursing Journal: Journal of the American Nephrology Nurses' Association
Tarja J Karpanen, Anna L Casey, Tony Whitehouse, Peter Nightingale, Ira Das, Thomas S J Elliott
BACKGROUND: A major source of microbial colonization of short-term central venous catheters (CVC) is the patients' endogenous skin microorganisms located at the CVC insertion site. The aim of this study was to determine if a transparent film dressing incorporating a 2% (weight/weight) chlorhexidine gluconate (CHG) gel decreases CVC and insertion site microbial colonization compared with a nonantimicrobial dressing in adult patients in critical care. METHODS: On CVC removal, samples for microbiological investigation were taken from both the skin surrounding the CVC insertion site and also from sutures securing the CVC...
January 1, 2016: American Journal of Infection Control
Iolanda Jordan Garcia, Elisabeth Esteban Torné, Amaya Bustinza Arriortua, Juan Carlos de Carlos Vicente, Patricia García Soler, José Andrés Concha Torre, José Carlos Flores González, Paula Madurga Revilla, Mercedes Palomar Martínez
INTRODUCTION: Nosocomial infections (NI) are a major healthcare problem. National surveillance systems enable data to be compared and to implement new measures to improve our practice. METHODS: A multicentre, prospective, descriptive and observational study was conducted using the data from surveillance system for nosocomial infections created in 2007 for Spanish pediatric intensive care units. Data were collected for one month, between 01 and 31 March, for every study year (2008-2012)...
May 2016: Enfermedades Infecciosas y Microbiología Clínica
Itaru Nakamura, Shinji Fukushima, Tsukako Hayakawa, Kentaro Sekiya, Tetsuya Matsumoto
PURPOSE: The additional costs of health care-associated infections vary depending on the reimbursement systems of different countries. We estimated the additional costs of central venous catheter-related bloodstream infections (CVC-CRBSI) in Japan, which has a universal health insurance system covering all citizens. METHODS: We conducted a retrospective matched case-control study. Twenty-two patients with CVC-CRBSI were identified among 2,148 patients treated between October 2011 and May 2014 in the intensive care unit of Tokyo Medical University Hospital (1,015 beds)...
October 1, 2015: American Journal of Infection Control
Silvia Virano, Carlo Scolfaro, Silvia Garazzino, Carlo De Intinis, Valeria Ghisetti, Irene Raffaldi, Carmelina Calitri, Pier Angelo Tovo
The aim of this survey was to describe the incidence, epidemiology, microbiology, risk factors and outcome of medical care related laboratory-confirmed bloodstream infections (LCBIs) observed during a twelve-month prospective study in a Paediatric Teaching Hospital in Turin, Italy. Inclusion criteria were clinical signs of sepsis and positivity of one or more of the following tests: blood culture, polymerase chain reaction for bacterial and fungal DNA on blood, and culture on intravascular device tips. In all, 140 episodes of sepsis were documented in 131 children: 37 (26...
June 2015: Le Infezioni in Medicina
Jasmin Rabensteiner, Georg Theiler, Wiebke Duettmann, Ines Zollner-Schwetz, Martin Hoenigl, Thomas Valentin, Eva Leitner, Josefa Luxner, Andrea Grisold, Angelika Valentin, Peter Neumeister, Robert Krause
BACKGROUND: Catheter-related bloodstream infections (CRBSIs) are currently detected in patients with clinically suspicion. The aim of our study was to evaluate whether CRBSIs could be anticipated and detected in a subclinical stage by peptide nucleic acid fluorescence in situ hybridization (PNA FISH) using universal hybridization probes or acridine orange leucocyte cytospin (AOLC) tests in haematooncological patients with central venous catheters (CVCs) in situ. MATERIALS AND METHODS: Peptide nucleic acid fluorescence in situ hybridization and AOLC tests using blood samples from one CVC lumen/port chamber in haematooncological patients were continuously performed...
August 2015: European Journal of Clinical Investigation
Maristela Böhlke, Gustavo Uliano, Franklin C Barcellos
PURPOSE: Infectious complications associated with central venous catheters (CVCs) are a major source of morbidity and mortality among hemodialysis (HD) patients. This review aims to discuss prevention, diagnosis criteria and management of CVC-related infections in HD patients. METHODS: We searched Medline for articles published in the last 10 years, with the keywords "catheter," "hemodialysis," "infection," "treatment," "diagnosis," "prophylaxis" and "adults." Only English language articles were reviewed...
September 2015: Journal of Vascular Access
María Guembe, María Jesús Pérez-Granda, Raquel Cruces, Pablo Martín-Rabadán, Emilio Bouza
Semiquantitative cultures of skin surrounding intravascular catheter entry sites and catheter hubs have high negative predictive values for catheter tip colonization. However, culturing samples from the inner side of the hub requires the catheter to be manipulated, thus increasing the risk of migration of microorganisms into the bloodstream. Today, hubs are closed using needleless connectors (NCs). Cultures of NCs could predict catheter colonization. Our objective was to compare the yield of NC sonicate cultures for prediction of catheter colonization with that of hub cultures...
July 2015: Journal of Clinical Microbiology
Annelisa Farah Silva Paes Leme, Aline Siqueira Ferreira, Fernanda Aparecida Oliveira Alves, Bruna Martinho de Azevedo, Liza Porcaro de Bretas, Rogerio Estevam Farias, Murilo Gomes Oliveira, Nádia Rezende Barbosa Raposo
The aim of this study was to investigate the in vitro and in vivo efficacy and the tissue reaction of an antibiofilm coating composed of xylitol, triclosan, and polyhexamethylene biguanide. The antimicrobial activity was analyzed by a turbidimetric method. Scanning electron microscopy was used to evaluate the antiadherent property of central venous catheter (CVC) fragments impregnated with an antibiofilm coating (I-CVC) in comparison with noncoated CVC (NC-CVC) fragments. Two in vivo assays using subcutaneous implantation of NC-CVC and I-CVC fragments in the dorsal area of rats were performed...
May 2015: Canadian Journal of Microbiology
Michał Ławiński, Krystyna Majewska, Iwona Fołtyn, Aleksandra Gradowska
UNLABELLED: In patients with chronic gastrointestinal tract failure, requiring access to the venous system, the subsequent catheter re-insertion are leading to large veins thrombosis impeding or preventing the insertion of another catheter and exposing patients to the risk of complications. Understanding the pathophysiology of catheter-related infections, enabled to use methods allowing to eradicate the source of infection without removal and replacement of central catheter with a new one...
December 2014: Polski Przeglad Chirurgiczny
Ayşe Karaaslan, Ahmet Soysal, Abdurrahman Sarmış, Eda Kepenekli Kadayifci, Kıvılcım Cerit, Serkan Atıcı, Güner Söyletir, Mustafa Bakır
Lactococcus lactis is a gram-positive coccus that is nonpathogenic in humans. Herein, we present the case of a 1-year-old boy with Down syndrome and Hirschprung's disease (HD) who developed a catheter-related bloodstream infection with L. lactis after gastrointestinal surgery. The patient had been hospitalized in the pediatric surgery unit from birth because of HD, and had undergone the Duhamel-Martin procedure which caused recurrent diarrhea episodes and feeding intolerance. On the infant's 430th day of life, he had an episode of gastroenteritis and feeding intolerance...
2015: Japanese Journal of Infectious Diseases
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