keyword
MENU ▼
Read by QxMD icon Read
search

mods

keyword
https://www.readbyqxmd.com/read/29148912/influence-of-different-restoration-techniques-on-fracture-resistance-of-root-filled-teeth-in-vitro-investigation
#1
M E Hshad, E E Dalkılıç, G C Ozturk, I Dogruer, F Koray
OBJECTIVE: The purpose of this study was to determine the fracture strength of endodontically treated mandibular premolar teeth restored with composites and different reinforcement techniques. METHODS AND MATERIALS: Forty-eight freshly extracted human mandibular premolar teeth were randomly divided into four groups: group IN, group CR, group FRC, and group PRF. Group IN consisted of teeth with intact crowns and served as the control group. In the other three groups, endodontic treatment was performed and standard mesio-occluso-distal (MOD) cavities were prepared...
November 17, 2017: Operative Dentistry
https://www.readbyqxmd.com/read/29143168/limited-influence-of-blunt-aortic-injuries-on-the-outcome-of-polytraumatized-patients-a-matched-pair-analysis
#2
A Omar, C Macke, M Winkelmann, E Beckmann, P Mommsen, C Schröter, C Krettek, Christian Zeckey
INTRODUCTION: Traumatic lesions of great vessels such as the aorta are life-threatening injuries. There is limited evidence about the influence of traumatic aortic injuries in multiple trauma patients in particular with regard to posttraumatic complications. The aim of this study was to evaluate the influence of blunt thoracic aortic injuries in multiple trauma patients compared to a multiple trauma cohort without this specific injury. In addition, the safety of Thoracic Endovascular Aortic Repair (TEVAR) in multiple trauma patients was analyzed...
November 15, 2017: Archives of Orthopaedic and Trauma Surgery
https://www.readbyqxmd.com/read/29141376/-clinical-significance-of-acute-gastrointestinal-injury-grades-in-inflammatory-response-of-critically-ill-patients
#3
J Wang, Y L Gao, W W Yu, Y H Xia, Y Z Sun
Objective: To explore the value of acute gastrointestinal injury (AGI) grades in inflammatory response of critically ill patients. Methods: Ptients with AGI severity from Ⅰ to Ⅳ were randomly selected(20 for each)from July 2014 to June 2015 in ICU of Yantai Yuhuangding Hospital. The expression of NF-κB were detected by immunofluorescence. The expression of TNF-α and IL-6 were detected by enzyme linked immunosorbent assay (ELISA). Procalcitonin (PCT) and C reactive protein (CRP) were measured. Statistical analysis was carried out...
November 14, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/29138874/using-il-6-concentrations-in-the-first-24%C3%A2-h-following-trauma-to-predict-immunological-complications-and-mortality-in-trauma-patients-a-meta-analysis
#4
REVIEW
Zhi Qiao, Weikang Wang, Luxu Yin, Peng Luo, Johannes Greven, Klemens Horst, Frank Hildebrand
PURPOSE: In previous studies, interleukin-6 (IL-6) has been shown to have a high predictive value for the development of complications and mortality after trauma; however, there is some uncertainty around these results. The aim of this meta-analysis was to assess the value of early IL-6 levels (within the first 24 h after trauma) for predicting post-traumatic complications [acute respiratory distress syndrome (ARDS), systemic inflammatory response syndrome (SIRS), sepsis, multiple organ failure (MOF), and multiple organ dysfunction syndrome (MODS)] and mortality...
November 14, 2017: European Journal of Trauma and Emergency Surgery: Official Publication of the European Trauma Society
https://www.readbyqxmd.com/read/29136343/pharmacokinetics-pharmacodynamics-and-safety-of-a-long-acting-human-growth-hormone-mod-4023-in-healthy-japanese-and-caucasian-adults
#5
William G Kramer, Michal Jaron-Mendelson, Ronit Koren, Oren Hershkovitz, Gili Hart
Daily injections of growth hormone (GH) as replacement therapy in GH-deficient (GHD) patients may cause poor compliance and inconvenience. C-terminal peptide-modified human GH (MOD-4023) has been developed for once-weekly administration in GHD adults and children. In the present study, the pharmacokinetics (PK) and pharmacodynamics (PD) of a single subcutaneous dose of MOD-4023 were evaluated in healthy Caucasian and Japanese adults, using a phase 1 double-blind, vehicle-controlled, randomized study design...
November 14, 2017: Clinical Pharmacology in Drug Development
https://www.readbyqxmd.com/read/29132339/sequential-e2-levels-not-ovarian-maximal-diameter-estimates-were-correlated-with-outcome-of-cetrotide-therapy-for-management-of-women-at-high-risk-of-ovarian-hyperstimulation-syndrome-a-randomized-controlled-study
#6
Khalid M Salama, Hesham M Abo Ragab, Mohammed F El Sherbiny, Ali A Morsi, Ibrahim I Souidan
BACKGROUND: Ovarian hyperstimulation syndrome (OHSS) is an important condition with considerable morbidity and a small risk of mortality and most commonly results as an iatrogenic condition following follicular stimulation of the ovaries. We aimed to evaluate safety and efficacy of 3-day cetrotide therapy started on day of oocyte retrieval (Day-0) in women at high-risk for development of ovarian hyperstimulation syndrome (OHSS) after GnRH agonist induction protocol. METHODS: Forty-eight women fulfilling inclusion criteria underwent ultrasound scanning for maximal ovarian diameter (MOD) estimation and ascites grading...
November 13, 2017: BMC Women's Health
https://www.readbyqxmd.com/read/29131067/estimation-of-trait-model-parameters-in-a-mod-score-linkage-analysis
#7
Markus Brugger, Susanne Rospleszcz, Konstantin Strauch
BACKGROUND/AIMS: Theoretically, the trait-model parameters (disease allele frequency and penetrance function) can be estimated without bias in a MOD score linkage analysis. We aimed to practically evaluate the MOD score approach regarding its ability to provide unbiased trait-model parameters for various pedigree-type and trait-model scenarios. We further investigated the ability of the MOD score approach to detect imprinting using affected sib pairs (ASPs) and affected half-sib pairs (AHSPs) when all parental genotypes are missing...
November 1, 2017: Human Heredity
https://www.readbyqxmd.com/read/29128128/cad-fe-modeling-and-analysis-of-class-ii-restorations-incorporating-resin-composite-glass-ionomer-and-glass-ceramic-materials
#8
Pietro Ausiello, Stefano Ciaramella, Massimo Martorelli, Antonio Lanzotti, Antonio Gloria, David C Watts
OBJECTIVES: To investigate the influence of specific resin-composite, glass ceramic and glass ionomer cement (GIC) material combinations in a "multi-layer" technique to replace enamel and dentin in class II mesio-occlusal-distal (MOD) dental restorations using 3D-Finite Element Analysis (FEA). METHODS: Four 3D-FE models (A-D) of teeth, adhesively restored with different filling materials, were created and analyzed in comparison with a 3D model (E) of a sound lower molar...
November 8, 2017: Dental Materials: Official Publication of the Academy of Dental Materials
https://www.readbyqxmd.com/read/29127325/acinar-injury-and-early-cytokine-response-in-human-acute-biliary-pancreatitis
#9
Aparna Jakkampudi, Ramaiah Jangala, Ratnakar Reddy, Sasikala Mitnala, G Venkat Rao, Rebala Pradeep, D Nageshwar Reddy, Rupjyoti Talukdar
Clinical acute pancreatitis (AP) is marked by an early phase of systemic inflammatory response syndrome (SIRS) with multiorgan dysfunction (MODS), and a late phase characterized by sepsis with MODS. However, the mechanisms of acinar injury in human AP and the associated systemic inflammation are not clearly understood. This study, for the first time, evaluated the early interactions of bile acid induced human pancreatic acinar injury and the resulting cytokine response. We exposed freshly procured resected human pancreata to taurolithocolic acid (TLCS) and evaluated for acinar injury, cytokine release and interaction with peripheral blood mononuclear cells (PBMCs)...
November 10, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29125770/comparison-of-resp-and-ipolq-mod-partial-charges-for-solvation-free-energy-calculations-of-various-solute-solvent-pairs
#10
Andreas Mecklenfeld, Gabriele Raabe
The calculation of solvation free energies ΔGsolv by molecular simulations is of great interest as they are linked to other physical properties such as relative solubility, partition coefficient, and activity coefficient. However, shortcomings in molecular models can lead to ΔGsolv deviations from experimental data. Various studies have demonstrated the impact of partial charges on free energy results. Consequently, calculation methods for partial charges aimed at more accurate ΔGsolv predictions are the subject of various studies in the literature...
November 10, 2017: Journal of Chemical Theory and Computation
https://www.readbyqxmd.com/read/29121465/co-culture-of-marine-invertebrate-associated-bacteria-and-interdisciplinary-technologies-enable-biosynthesis-and-discovery-of-a-new-antibiotic-keyicin
#11
Navid Adnani, Marc Chevrette, Srikar N Adibhatla, Fan Zhang, Qing Yu, Doug R Braun, Justin Nelson, Scott W Simpkins, Bradon R McDonald, Chad L Myers, Jeff S Piotrowski, Christopher J Thompson, Cameron R Currie, Lingjun Li, Scott R Rajski, Tim S Bugni
Advances in genomics and metabolomics have made clear in recent years that microbial biosynthetic capacities on Earth far exceed previous expectations. This is attributable, in part, to the realization that most microbial natural product (NP) producers harbor biosynthetic machineries not readily amenable to classical laboratory fermentation conditions. Such "cryptic" or dormant biosynthetic gene clusters (BGCs) encode for a vast assortment of potentially new antibiotics and, as such, have become extremely attractive targets for activation under controlled laboratory conditions...
November 9, 2017: ACS Chemical Biology
https://www.readbyqxmd.com/read/29115823/an-overview-of-the-clinical-uses-pharmacology-and-safety-of-modafinil
#12
Eric Murillo-Rodriguez, André Barciela Veras, Nuno Barbosa Rocha, Henning Budde, Sérgio Machado
Modafinil (MOD) is a drug used for the management of excessive daytime sleepiness observed in several sleep disturbances such as shift work sleep disorder, obstructive sleep apnea, restless leg syndrome and narcolepsy. Additionally, a wide scope of medical uses of MOD have been described such as fatigue in subjects with depression as well as patients under chemotherapy. Moreover, there also appear to be a cognitive enhancer drug. In contrast, recent reports have indicated the risk of developing addiction to MOD...
November 8, 2017: ACS Chemical Neuroscience
https://www.readbyqxmd.com/read/29115473/clinical-application-of-a-novel-diagnostic-scheme-including-pancreatic-%C3%AE-%C3%A2-cell-dysfunction-for-traumatic-multiple-organ-dysfunction-syndrome
#13
Zhan-Ke Wang, Rong-Jian Chen, Shi-Liang Wang, Guang-Wei Li, Zhong-Zhen Zhu, Qiang Huang, Zi-Li Chen, Fan-Chang Chen, Lei Deng, Xiao-Peng Lan, Tian Hu
A novel diagnostic scheme that includes pancreatic β‑cell dysfunction analysis for the diagnosis of traumatic multiple organ dysfunction syndrome (MODS) was investigated to assist in the early diagnosis and detection of MODS. Early intervention and treatment of MODS has been associated with a reduced mortality rate. A total of 2,876 trauma patients (including patients post‑major surgery) were admitted to the intensive care unit of the authors' hospital between December 2010 and December 2015 and enrolled in the present study...
October 26, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/29105961/ultrasound-and-haematological-changes-during-the-early-luteal-phase-in-women-at-high-risk-for-developing-ovarian-hyperstimulation-syndrome
#14
George T Lainas, Tryfon G Lainas, Christos A Venetis, Ioannis A Sfontouris, Ioannis Z Zorzovilis, Efthymia Alexopoulou, Basil C Tarlatzis, Efstratios M Kolibianakis
OBJECTIVE: To assess ultrasound and haematological changes in ovarian hyperstimulation syndrome (OHSS) during the early luteal phase in women at high risk for developing OHSS. METHODS: This is a retrospective cohort study of 319 women undergoing in-vitro fertilisation (IVF), at high risk for OHSS following human chorionic gonadotrophin (hCG) triggering of final oocyte maturation. Patients were treated with GnRH agonist or antagonist protocol and were monitored for 5 days post oocyte retrieval...
November 6, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29101529/an-overview-of-cytokines-and-heat-shock-response-in-polytraumatized-patients
#15
REVIEW
Maria Concepción Guisasola, Berta Alonso, Beatriz Bravo, Javier Vaquero, Francisco Chana
Early after injury, local tissue damage induces a local and systemic inflammatory response that activates the immune system and leads to the development of systemic inflammatory response syndrome (SIRS). This post-traumatic response often results in uncontrolled release of inflammatory mediators and over-activation of the immune system, which occasionally results in multiple organ dysfunction syndrome (MODS). In parallel, a state of immunosuppression develops. This counter-regulating suppression of different cellular and humoral immune functions has been termed "compensatory anti-inflammatory response syndrome (CARS)...
November 3, 2017: Cell Stress & Chaperones
https://www.readbyqxmd.com/read/29101474/correction-to-human-cd200-suppresses-macrophage-mediated-xenogeneic-cytotoxicity-and-phagocytosis
#16
Rieko Sakai, Akira Maeda, Thuy-Vy Choi, Pei-Chi Lo, Patmika Jiaravuthisan, Afifah Mod Shabri, Han-Tang Wang, Rei Matsuura, Tasuku Kodama, Hiroshi Eguchi, Hiroomi Okuyama, Shuji Miyagawa
In the original publication, the fifth author name was erroneously published as "Patmika Jiaravuthiasan". The correct author name should read as, "Patmika Jiaravuthisan". The original article was corrected.
November 3, 2017: Surgery Today
https://www.readbyqxmd.com/read/29101294/content-analysis-of-e-cigarette-products-promotions-prices-and-claims-on-internet-tobacco-vendor-websites-2013-2014
#17
Rebecca S Williams, Jason Derrick, Aliza K Liebman, Kevin LaFleur
OBJECTIVE: To identify the population of Internet e-cigarette vendors (IEVs) and conduct content analysis of products sold and IEVs' promotional, claims and pricing practices. METHODS: Multiple sources were used to identify IEV websites, primarily complex search algorithms scanning over 180 million websites. In 2013, 32 446 websites were manually screened, identifying 980 IEVs, with the 281 most popular selected for content analysis. This methodology yielded 31 239 websites for manual screening in 2014, identifying 3096 IEVs, with 283 selected for content analysis...
November 3, 2017: Tobacco Control
https://www.readbyqxmd.com/read/29090590/personal-interpersonal-and-organizational-predictors-of-the-mode-of-delivery-among-urban-women-a-prospective-study-with-socio-ecological-approach
#18
Fatemeh Bakhtari, Haidar Nadrian, Hossein Matlabi, Parvin Sarbakhsh, Maryam Bidar
The aim of this prospective study was to investigate the predictors of choosing mode of delivery (MOD) among Iranian urban women applying the socio-ecological model. In 2015, a convenient sample of 530 pregnant women in urban regions of Urmia, Iran, was recruited to complete a socio-ecological approach-based questionnaire. Then, 1 week after childbirth, the women were followed up by telephone to be asked about their MOD (response rate = 81.88%). Logistic regression analysis showed that the odds of cesarean section (CS) among the women with university education, whose husbands were an employee in a governmental organization, who preferred a private hospital for delivery, and who selected the CS as the preferred MOD during pregnancy were significantly higher than their counterparts...
October 1, 2017: Clinical Nursing Research
https://www.readbyqxmd.com/read/29063606/harnessing-meta-analysis-to-refine-an-oncology-patient-population-for-physiology-based-pharmacokinetic-modeling-of-drugs
#19
Emily Schwenger, Venkatesh Pilla Reddy, Ganesh Moorthy, Pradeep Sharma, Helen Tomkinson, Eric Masson, Karthick Vishwanathan
Certain oncology compounds exhibit fundamental PK disparities between healthy and malignant conditions. Given the effects of tumor-associated inflammation on enzyme and transporter expression, we performed a meta-analysis of CYP- and transporter-sensitive substrate clinical PK to quantitatively compare enzyme and transporter abundances between healthy volunteers (HV) and cancer patients (CP). Hepatic and intestinal CYP1A2, CYP2C19, and CYP3A4 abundance were subsequently adjusted via Simcyp®'s sensitivity analysis tool...
October 24, 2017: Clinical Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/29061429/role-of-inflammatory-and-hemostatic-biomarkers-in-alzheimer-s-and-vascular-dementia-a-pilot-study-from-a-tertiary-center-in-northern-india
#20
V Y Vishnu, M Modi, V K Garg, M Mohanty, M K Goyal, V Lal, B R Mittal, S Prabhakar
INTRODUCTION: A reliable plasma biomarker in differentiating between Alzheimer's disease (AD) and Vascular dementia (VaD) is the need of the hour, in most memory clinics. Even though there is no disease modifying treatment, it is important to know the type of dementia for both symptomatic treatment and prognostication. METHODS: Neuropsychological assessment, MRI brain, FDG-PET brain and CSF biomarkers of AD (Aβ42 and total tau) were used for establishing the diagnosis of Mild Cognitive Impairment (MCI), AD or VaD...
October 2017: Asian Journal of Psychiatry
keyword
keyword
35810
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"