keyword
MENU ▼
Read by QxMD icon Read
search

mods

keyword
https://www.readbyqxmd.com/read/28420477/-metabolism-of-high-density-lipoprotein-and-the-research-progress-of-its-effects-on-sepsis
#1
Meiyun Liu, Huanping Zhou, Xin Lyu
Sepsis is a high-risk factor for the death of critical patients. High density lipoprotein (HDL) are the major protective serum proteins, and the serum levels of HDL are closely related to the severity of sepsis. The anti-inflammatory and anti-oxidation properties of HDL, may be able to play an important role in the innate immune response. Thereby it may reduce the damage of septic shock and multiple organ dysfunction syndrome (MODS) in animals or human beings, and improve the prognosis. In order to unveil the metabolism of HDL in septic patients and its effects on both progression and prognosis of sepsis, this review not only focuses on the composition and structure of HDL, but also analyzes its pivotal role in inflammatory immune response and anti-oxidation...
April 2017: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
https://www.readbyqxmd.com/read/28420460/-bone-marrow-mesenchymal-stem-cells-modulated-the-inflammatory-response-by-regulating-the-expression-of-il-4-and-rage-products-in-the-rats-with-mods
#2
Xia Zhou, Guanghui Xiu, Yichao Zhu, Xiaolei Chen, Wei Xiong, Xinghua Pan, Jie Sun, Bin Ling
OBJECTIVE: To investigate the underlying mechanism of bone marrow mesenchymal stem cells (BMSC) modulating the inflammatory response during the multiple organ dysfunction syndrome (MODS), especially the expression of inflammatory cytokines, which will provide new theoretical and experimental basis of MODS in clinic. METHODS: BMSC of Sprague-Dawley (SD) rat (female, 4 weeks) was extracted and cultivated, and the 4th passage were used in experimental study. According to the random number table, 60 female SD rats were divided into three groups (n = 20 per group): sham group, MODS group, BMSC group...
April 2017: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
https://www.readbyqxmd.com/read/28414569/elevated-levels-of-plasma-mitochondrial-dna-are-associated-with-clinical-outcome-in-intra-abdominal-infections-caused-by-severe-trauma
#3
Qiongyuan Hu, Jianan Ren, Jie Wu, Guanwei Li, Xiuwen Wu, Song Liu, Gefei Wang, Guosheng Gu, Jieshou Li
BACKGROUND: The purpose of our study was to determine prospectively relationships between plasma mitochondrial deoxyribonucleic acid (mtDNA) concentration and clinical outcome in patients with intra-abdominal infections (IAIs) induced by severe abdominal trauma. PATIENTS AND METHODS: The DNA was isolated from serum samples taken from patients with IAIs at hospital days zero, one, and two. Plasma mtDNA concentration was assessed by real-time polymerase chain reaction (PCR)...
April 17, 2017: Surgical Infections
https://www.readbyqxmd.com/read/28413061/mechanical-behavior-of-bulk-direct-composite-versus-block-composite-and-lithium-disilicate-indirect-class-ii-restorations-by-cad-fem-modeling
#4
Pietro Ausiello, Stefano Ciaramella, Andrea Fabianelli, Antonio Gloria, Massimo Martorelli, Antonio Lanzotti, David C Watts
OBJECTIVES: To study the influence of resin based and lithium disilicate materials on the stress and strain distributions in adhesive class II mesio-occlusal-distal (MOD) restorations using numerical finite element analysis (FEA). To investigate the materials combinations in the restored teeth during mastication and their ability to relieve stresses. METHODS: One 3D model of a sound lower molar and three 3D class II MOD cavity models with 95° cavity-margin-angle shapes were modelled...
April 13, 2017: Dental Materials: Official Publication of the Academy of Dental Materials
https://www.readbyqxmd.com/read/28410931/a-model-of-recovery-from-inhalation-injury-and-cutaneous-burn-in-ambulatory-swine
#5
David M Burmeister, Matthew K McIntyre, Brendan Beely, Bryan Jordan, Kerfoot P Walker, James K Aden, Andriy Batchinsky, Kevin K Chung, Leopoldo C Cancio, Robert J Christy
Inhalation injury commonly accompanies thermal injury, increasing the likelihood of mortality and multiple organ dysfunction (MOD). Large animal models have given important insight into the pathophysiology of this injury; however recapitulating late MOD has remained difficult. The current report describes experiments using a smoke inhalation and burn model, with follow-up of ambulatory swine for 14days with bronchoscopy, CT scanning, and bronchoalveolar lavage fluid (BALF)/blood collection. Clinically, animals cleared airway damage in the first several days after-injury...
April 11, 2017: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/28402737/comparison-of-polymerization-shrinkage-physical-properties-and-marginal-adaptation-of-flowable-and-restorative-bulk-fill-resin-based-composites
#6
J H Jung, S H Park
PURPOSE: The purpose of this study was to compare the marginal adaptation of two flowable bulk fill resin-based composites (FB-RBCs), two restorative bulk fill resin-based composites (RB-RBCs), and one regular incremental-fill RBC in MOD cavities in vitro. Additionally, the influence of linear polymerization shrinkage, shrinkage force, flexural modulus, and bottom/top surface hardness ratio on the marginal adaptation was evaluated. METHODS: A Class II MOD cavity was prepared in 40 extracted sound lower molars...
April 12, 2017: Operative Dentistry
https://www.readbyqxmd.com/read/28399519/pharmacokinetic-and-pharmacodynamic-modeling-of-mod-4023-a-long-acting-human-growth-hormone-in-growth-hormone-deficiency-children
#7
Dennis M Fisher, Ron G Rosenfeld, Michal Jaron-Mendelson, Leanne Amitzi, Ronit Koren, Gili Hart
BACKGROUND/AIMS: MOD-4023 is a long-acting human growth hormone (hGH) in clinical trials for the treatment of growth hormone deficiency (GHD). A key goal is maintenance of serum concentrations of insulin-like growth factor (IGF) 1 within normal range throughout GH dosing. The study aimed to develop a pharmacokinetic model for MOD-4023 and a pharmacodynamic model for the effect of MOD-4023 on IGF-1 to allow estimation of peak and mean IGF-1 and to identify the optimal IGF-1 sampling day...
April 11, 2017: Hormone Research in Pædiatrics
https://www.readbyqxmd.com/read/28385919/supplementing-an-energy-adequate-higher-protein-diet-with-protein-does-not-enhance-fat-free-mass-restoration-after-short-term-severe-negative-energy-balance
#8
Claire E Berryman, John J Sepowitz, Holly L McClung, Harris R Lieberman, Emily K Farina, James P McClung, Arny A Ferrando, Stefan M Pasiakos
Negative energy balance during military operations can be severe and result in significant reductions in fat-free mass (FFM). Consuming supplemental high-quality protein following such military operations may accelerate restoration of FFM. Body composition (dual-energy x-ray absorptiometry) and whole-body protein turnover (single-pool (15)N-alanine method) were determined before (PRE) and after 7 d (POST) of severe negative energy balance during military training in 63 male US Marines (mean±SD, 25±3 y, 84±9 kg)...
April 6, 2017: Journal of Applied Physiology
https://www.readbyqxmd.com/read/28385430/clinician-assessments-and-patient-perspectives-of-single-tooth-implant-restorations-in-the-esthetic-zone-of-the-maxilla-a-systematic-review
#9
REVIEW
Sirikarn P Arunyanak, Adrien Pollini, Athanasios Ntounis, Dean Morton
STATEMENT OF PROBLEM: Esthetic outcomes associated with implant dentistry are important to both clinicians and patients. However, esthetic satisfaction may vary between the 2 groups. In order to evaluate the current publications relating to this topic, the following focused question was developed, "what are the quantitative and qualitative differences between clinician evaluations and patient perspectives in the assessment of single-tooth implant outcomes in the esthetic zone?" PURPOSE: The purpose of this systematic review was to identify differences in esthetic satisfaction between clinicians and patients when evaluating single-tooth implant-supported restorations...
April 3, 2017: Journal of Prosthetic Dentistry
https://www.readbyqxmd.com/read/28380442/monocytes-endoplasmic-reticulum-stress-and-metabolomics-in-dogs-with-multiple-organ-dysfunction-syndrome-treated-by-continuous-venovenous-hemodiafiltration
#10
Yun-Peng Xu, Xiao-Lu Sui, Ai-Sha Zhang, Lei Ye, Feng-Juan Gu, Ji-Hong Chen
OBJECTIVES: We tried to investigate the mechanism of continuous venovenous hemodiafiltration (CVVHDF) treatment in monocytes function, endoplasmic reticulum (ER) stress signaling pathways, metabolomics and histopathological changes of MODS dogs, and aimed to enhance the understanding of pathogenesis and provide novel avenues to potential therapies. METHODS: 12 male Beagle dogs were used to develop the stable models of MODS by using hemorrhagic shock plus resuscitation and endotoxemia, and assigned randomly to CVVHDF group (n=6) and MODS group (n=6)...
March 23, 2017: Oncotarget
https://www.readbyqxmd.com/read/28380276/microscopic-observation-drug-susceptibility-assay-vs-xpert-%C3%A2-mtb-rif-for-the-diagnosis-of-tuberculosis-in-a-rural-african-setting-a-cost-utility-analysis
#11
Philip Erick Wikman-Jorgensen, Jara Llenas-García, Tomàs María Pérez-Porcuna, Michael Hobbins, Jochen Ehmer, Manuel Aly Mussa, Carlos Ascaso
OBJECTIVE: To compare the cost-utility of Microscopic Observation Drug-Susceptibility Assay (MODS) and Xpert(®) MTB/RIF implementation for TB diagnosis in rural northern Mozambique. METHODS: Stochastic transmission compartmental TB model from the health care provider perspective with parameter input from direct measurements, systematic literature reviews, and expert opinion. MODS and Xpert(®) MTB/RIF were evaluated as replacement test of smear microscopy (SM) or as an add-on test after a negative SM...
April 5, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/28367022/concurrent-evaluation-of-microscopic-observation-of-drug-susceptibility-assay-for-pulmonary-and-extrapulmonary-tuberculosis
#12
Sonali Sudhir Zadbuke, Reena Set, Nishat Khan, Jayanthi Shastri
BACKGROUND: Methods for detection and drug susceptibility of tuberculosis (TB) with solid media are inexpensive but slow and laborious. Rapid methods to diagnose TB and multidrug-resistant TB (MDR-TB) are a global priority for TB control. OBJECTIVES: A study was performed to compare the sensitivity of detection of mycobacterial growth and time of culture positivity by microscopic observation of drug susceptibility (MODS) assay with that of Lowenstein-Jensen (LJ) culture in pulmonary and extrapulmonary TB and to evaluate the concordance of the susceptibilities to isoniazid (INH) and rifampicin (RIF) by MODS and proportion method on LJ...
April 2017: Journal of Laboratory Physicians
https://www.readbyqxmd.com/read/28361006/regulatory-mechanisms-prophylaxis-and-treatment-of-vascular-leakage-following-severe-trauma-and-shock
#13
REVIEW
Chen-Yang Duan, Jie Zhang, Hui-Ling Wu, Tao Li, Liang-Ming Liu
Vascular leakage, or increased vascular permeability, is a common but important pathological process for various critical diseases, including severe trauma, shock, sepsis, and multiple organ dysfunction syndrome (MODS), and has become one of the most important causes of death for intensive care units (ICU) patients. Currently, although there has been some progress in knowledge of the pathogenesis of these vascular disorders, the detailed mechanisms remain unclear, and effective prophylaxis and treatment are still lacking...
2017: Military Medical Research
https://www.readbyqxmd.com/read/28357580/the-relationship-between-oxygen-uptake-kinetics-and-neuromuscular-fatigue-in-high-intensity-cycling-exercise
#14
John Temesi, Felipe Mattioni Maturana, Arthur Peyrard, Tatiane Piucco, Juan M Murias, Guillaume Y Millet
PURPOSE: In theory, a slow oxygen uptake ([Formula: see text]) kinetics leads to a greater accumulation of anaerobic by-products, which can, in turn, induce more neuromuscular fatigue. However, the existence of this relationship has never been tested. METHODS: After two sessions to measure peak [Formula: see text], peak power output (POpeak), and [Formula: see text] kinetics responses in the unfatigued state (τ [Formula: see text] MOD), 10 healthy young adults performed a 6-min cycling bout at 80% POpeak (INT6-min)...
March 29, 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/28350760/involvement-of-hsp70-and-ho-1-in-the-protective-effects-of-raloxifene-on-multiple-organ-dysfunction-syndrome-by-endotoxemia-in-ovariectomized-rats
#15
Hsin-Hsueh Shen, Shieh-Yang Huang, Pao-Yun Cheng, Yen-Ju Chu, Shu-Ying Chen, Kwok-Keung Lam, Yen-Mei Lee
OBJECTIVE: Accumulating evidence demonstrates that raloxifene, a selective estrogen receptor modulator, possesses anti-inflammatory action. This study evaluates the preventive effects of long-term treatment of raloxifene on acute inflammation and multiple organ dysfunction syndrome (MODS) in ovariectomized (OVX) rats with endotoxemia and its underlying mechanism of action. METHODS: Adult female rats were OVX bilaterally to induce estrogen insufficiency. OVX rats were administered with raloxifene (1 mg/kg, gavage, once daily) for 8 weeks, beginning 1 week after surgery, followed by induction of sepsis via intravenous infusion of lipopolysaccharides (LPS; 30 mg/kg) for 4 hours...
March 27, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28343394/metal-organic-nanosheets-formed-via-defect-mediated-transformation-of-a-hafnium-metal-organic-framework
#16
Matthew J Cliffe, Elizabeth Castillo-Martínez, Yue Wu, Jeongjae Lee, Alexander C Forse, Francesca C N Firth, Peyman Z Moghadam, David Fairen-Jimenez, Michael W Gaultois, Joshua A Hill, Oxana V Magdysyuk, Ben Slater, Andrew L Goodwin, Clare P Grey
We report a hafnium-containing MOF, hcp UiO-67(Hf), which is a ligand-deficient layered analogue of the face-centered cubic fcu UiO-67(Hf). hcp UiO-67 accommodates its lower ligand:metal ratio compared to fcu UiO-67 through a new structural mechanism: the formation of a condensed "double cluster" (Hf12O8(OH)14), analogous to the condensation of coordination polyhedra in oxide frameworks. In oxide frameworks, variable stoichiometry can lead to more complex defect structures, e.g., crystallographic shear planes or modules with differing compositions, which can be the source of further chemical reactivity; likewise, the layered hcp UiO-67 can react further to reversibly form a two-dimensional metal-organic framework, hxl UiO-67...
April 5, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28338164/-a-prospective-randomized-controlled-trial-of-laparoscopic-repair-versus-open-repair-for-perforated-peptic-ulcers
#17
Qiwei Wang, Bujun Ge, Qi Huang
OBJECTIVE: To compared the clinical efficacy of laparoscopic repair (LR) versus open repair (OR) for perforated peptic ulcers. METHODS: From January 2010 to June 2014, in Shanghai Tongji Hospital, 119 patients who were diagnosed as perforated peptic ulcers and planned to receive operation were prospectively enrolled. Patients were randomly divided into LR (58 patients) and OR(61 patients) group by computer. Intra-operative and postoperative parameters were compared between two groups...
March 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/28338044/effect-of-decomposition-and-organic-residues-on-resistivity-of-copper-films-fabricated-via-low-temperature-sintering-of-complex-particle-mixed-dispersions
#18
Yingqiong Yong, Mai Thanh Nguyen, Hiroki Tsukamoto, Masaki Matsubara, Ying-Chih Liao, Tetsu Yonezawa
Mixtures of a copper complex and copper fine particles as copper-based metal-organic decomposition (MOD) dispersions have been demonstrated to be effective for low-temperature sintering of conductive copper film. However, the copper particle size effect on decomposition process of the dispersion during heating and the effect of organic residues on the resistivity have not been studied. In this study, the decomposition process of dispersions containing mixtures of a copper complex and copper particles with various sizes was studied...
March 24, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28334105/biojava-modfinder-identification-of-protein-modifications-in-3d-structures-from-the-protein-data-bank
#19
Jianjiong Gao, Andreas Prlic, Chunxiao Bi, Wolfgang F Bluhm, Dimitris Dimitropoulos, Dong Xu, Philip E Bourne, Peter W Rose
Summary: We developed a new software tool, BioJava-ModFinder, for identifying protein modifications observed in 3D structures archived in the Protein Data Bank (PDB). Information on more than 400 types of protein modifications were collected and curated from annotations in PDB, RESID, and PSI-MOD. We divided these modifications into three categories: modified residues, attachment modifications, and cross-links. We have developed a systematic method to identify these modifications in 3D protein structures...
February 17, 2017: Bioinformatics
https://www.readbyqxmd.com/read/28332982/mod-special-issue-on-the-roles-of-physical-forces-in-animal-development
#20
EDITORIAL
Christian Dahmann
No abstract text is available yet for this article.
April 2017: Mechanisms of Development
keyword
keyword
35810
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"