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Local anesthesia and dexamethasone

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https://www.readbyqxmd.com/read/27833337/eventuality-of-dexamethasone-injected-intra-massetrically-on-post-operative-sequel-following-the-surgical-extraction-of-impacted-mandibular-third-molars-a-prospective-study
#1
G D Nandini
OBJECTIVE: The objective of the study was to compare the efficacy of dexamethasone given intra-massetrically via intra buccal approach on postoperative sequele after surgical extraction of impacted mandibular third molars. METHODOLOGY: Twenty patients, each of who required surgical extraction of a single impacted mandibular third molar under local anesthesia, were randomly set apart to one of the two groups of ten each. The experimental group received dexamethasone 8 mg injected to the masseter muscle intra buccally and the control group did not receive any steroid...
December 2016: Journal of Maxillofacial and Oral Surgery
https://www.readbyqxmd.com/read/27790253/effect-of-dexamethasone-intraligamentary-injection-on-post-endodontic-pain-in-patients-with-symptomatic-irreversible-pulpitis-a-randomized-controlled-clinical-trial
#2
Payman Mehrvarzfar, Ehsan Esnashari, Reyhaneh Salmanzadeh, Mahta Fazlyab, Mahyar Fazlyab
INTRODUCTION: The aim of this randomized-controlled clinical trial was to assess the effect of intraligamentary (PDL) injection of dexamethasone on onset and severity of post-treatment pain in patients with symptomatic irreversible pulpitis. METHODS AND MATERIALS: A total number of 60 volunteers were included according to the inclusion criteria and were assigned to three groups (n=20). After administration of local anesthesia and before treatment, group 1 (control) PDL injection was done with syringe containing empty cartridge, while in groups 2 and 3 the PDL injection was done with 0...
2016: Iranian Endodontic Journal
https://www.readbyqxmd.com/read/27755433/effect-of-oral-administration-of-bromelain-on-postoperative-discomfort-after-third-molar-surgery
#3
Paolo Ghensi, Alessandro Cucchi, Luca Creminelli, Cristiano Tomasi, Barbara Zavan, Carlo Maiorana
INTRODUCTION: The purpose of this prospective randomized controlled clinical trial was to evaluate the effect of oral administration of bromelain on discomfort after mandibular third molar surgery. MATERIALS AND METHODS: Eighty-four consecutive patients requiring surgical removal of a single mandibular impacted third molar under local anesthesia were randomly assigned to receiving no drug (control group, Group A), postoperative 40 mg bromelain every 6 hours for 6 days (Group B), preoperative 4 mg dexamethasone sodium phosphate as a submucosal injection (Group C), and preoperative 4 mg dexamethasone sodium phosphate as a submucosal injection plus postoperative 40 mg bromelain every 6 hours for 6 days (Group D)...
October 14, 2016: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/27733325/perineural-dexamethasone-does-not-enhance-the-analgesic-efficacy-of-ultrasound-guided-subcostal-transversus-abdominis-plane-block-during-laparoscopic-cholecystectomy
#4
Sheng-Hui Huang, Jing Lu, Hong-Yun Gan, Yi Li, Yong-Gang Peng, Shuan-Ke Wang
BACKGROUND: Ultrasound-guided transversus abdominis plane (TAP) block is an adjunct therapy to provide effective postoperative analgesia in abdominal surgical procedures. Dexamethasone is a supplement agent that can improve the efficacy of local anesthesia. However, information about its additive effect is limited. This study aimed to compare the analgesic efficiency using ultrasound-guided TAP block with and without perineural dexamethasone for patients who underwent laparoscopic cholecystectomy...
October 2016: Hepatobiliary & Pancreatic Diseases International: HBPD INT
https://www.readbyqxmd.com/read/27716229/particulate-steroid-betamethasone-added-to-ropivacaine-in-interscalene-brachial-plexus-block-for-arthroscopic-rotator-cuff-repair-improves-postoperative-analgesia
#5
Kunitaro Watanabe, Joho Tokumine, Tomoko Yorozu, Kumi Moriyama, Hideaki Sakamoto, Tetsuo Inoue
BACKGROUND: Dexamethasone added to local anesthetic for brachial plexus block improves postoperative pain after arthroscopic rotator cuff repair, as compared with the use of local anesthetic alone. Dexamethasone is present in non-particulate form in local anesthetic solution, while betamethasone is partially present in particulate form. The particulate betamethasone gradually decays and is expected to cause its longer-lasting effect. This study investigated the postoperative analgesic effect of betamethasone added to ropivacaine for brachial plexus block in patients who underwent arthroscopic rotator cuff repair...
October 4, 2016: BMC Anesthesiology
https://www.readbyqxmd.com/read/27663451/a-randomized-comparison-between-intravenous-and-perineural-dexamethasone-for-ultrasound-guided-axillary-block
#6
Julian Aliste, Prangmalee Leurcharusmee, Phatthanaphol Engsusophon, Aida Gordon, Giuliano Michelagnoli, Chonticha Sriparkdee, Worakamol Tiyaprasertkul, Dana Q Tran, Tom C R V Van Zundert, Roderick J Finlayson, De Q H Tran
BACKGROUND: This randomized double-blinded trial compared the effect of intravenous and perineural dexamethasone (8 mg) on the duration of motor block for ultrasound (US)-guided axillary brachial plexus block (AXB). METHODS: Patients undergoing upper limb surgery with US-guided AXB were randomly allocated to receive preservative-free dexamethasone (8 mg) via intravenous (n = 75) or perineural (n = 75) administration. The local anesthetic agent, 1% lidocaine -0...
September 23, 2016: Canadian Journal of Anaesthesia, Journal Canadien D'anesthésie
https://www.readbyqxmd.com/read/27662065/local-infiltration-of-analgesics-at-surgical-wound-to-reduce-postoperative-pain-after-laparotomy-in-rats
#7
Jeffrey S Kroin, Jinyuan Li, Mario Moric, Brian W Birmingham, Kenneth J Tuman, Asokumar Buvanendran
BACKGROUND AND OBJECTIVES: There is an increasing use of local infiltration analgesia (LIA) to reduce postoperative pain. Despite widespread use of LIA, wide variations in drug combinations and concomitant use of systemic analgesics have made it difficult to determine the optimal drug combinations for LIA. Using a previously validated rat laparotomy model, the optimal LIA combination of medications to reduce postoperative pain was determined. METHODS: Laparotomy was performed in an adult rat model under isoflurane anesthesia...
September 22, 2016: Regional Anesthesia and Pain Medicine
https://www.readbyqxmd.com/read/27283723/high-performance-liquid-chromatography-determination-of-dexamethasone-in-plasma-to-evaluate-its-systemic-absorption-following-intra-space-pterygomandibular-injection-of-twin-mix-mixture-of-2%C3%A2-lignocaine-with-1-200-000-epinephrine-and-4%C3%A2-mg-dexamethasone-randomized
#8
Darpan Bhargava, Ashwini Deshpande, Shaji Thomas, Yogesh Sharma, Piush Khare, Sanjeev Kumar Sahu, Suyash Dubey, Ankit Pandey, K Sreekumar
PURPOSE: To determine systemic absorption of dexamethasone by detection of plasma concentration using high performance liquid chromatography following its administration along with local anesthetic agent as a mixture via pterygomandibular space. METHODS: A prospective randomized double-blind clinical study was undertaken to analyze the plasma concentration of dexamethasone after intra-space pterygomandibular injection along with local anesthesia. The study was performed as per split mouth model where the mandibular quadrant allocation was done on a random basis considering each of the 30 patients is included in the two study interventions (SS and CS)...
September 2016: Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/27195644/back-pain-and-neuraxial-anesthesia
#9
Honorio T Benzon, Yogen G Asher, Craig T Hartrick
The incidence of back pain after neuraxial anesthesia in the adult population is not different from that after general anesthesia. The pain is usually mild, localized in the low back, rarely radiates to the lower extremities, and has a duration of only a few days. The risk factors for development of back pain include the lithotomy position, multiple attempts at block placement, duration of surgery longer than 2.5 hours, body mass index ≥32 kg/m, and a history of back pain. However, there is no permanent worsening of preexisting back pain after neuraxial anesthesia...
June 2016: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/27192920/-the-diagnosis-and-treatment-of-one-huge-cystic-lymphangioma-in-etropharyngeal-space
#10
Hua Zhang, Xicheng Song, Chuanliang Jia
One child was hospitalized because of repeated cough and sputum. The biopsy diagnosis in local hospital was cystic lymphangioma in retropharyngeal space. We carried out transoral incision and drainage by catheter under general anesthesia. Put into the surgical cavity a suction drainage tube, and injected 5 mg dexamethasone and 8mg Bleomycin. He had nasogastric liquid diet after operation. We removed the suction drainage tube two weeks later. No recurrence was found following up over two years.
January 2016: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
https://www.readbyqxmd.com/read/27015546/a-multicenter-randomized-comparison-between-intravenous-and-perineural-dexamethasone-for-ultrasound-guided-infraclavicular-block
#11
Prangmalee Leurcharusmee, Julian Aliste, Tom C R V Van Zundert, Phatthanaphol Engsusophon, Vanlapa Arnuntasupakul, Worakamol Tiyaprasertkul, Amornrat Tangjitbampenbun, Sonia Ah-Kye, Roderick J Finlayson, De Q H Tran
BACKGROUND AND OBJECTIVES: This multicenter, randomized trial compared intravenous (IV) and perineural (PN) dexamethasone for ultrasound (US)-guided infraclavicular brachial plexus block. Our research hypothesis was both modalities would result in similar durations of motor block. METHODS: One hundred fifty patients undergoing upper limb surgery with US-guided infraclavicular block were randomly allocated to receive IV or PN dexamethasone (5 mg). The local anesthetic agent (35 mL of lidocaine 1%-bupivacaine 0...
May 2016: Regional Anesthesia and Pain Medicine
https://www.readbyqxmd.com/read/26952122/-glucocorticoids-as-an-adjunct-in-peripheral-regional-anesthesia-move-to-the-holy-grail-of-perineural-analgesia
#12
T Wiesmann, T Volk, T Steinfeldt
BACKGROUND: The role of dexamethasone as an adjunct in peripheral nerve blockades is still unclear. OBJECTIVES: This article reviews the actual knowledge and scientific evidence for dexamethasone as an adjunct in peripheral regional anesthesia. Moreover, it discusses the benefits of the systemic versus the perineural mode of application. RESULTS: Dexamethasone prolongs sensible as well as motor blockades in peripheral nerve blocks when applied intravenously or perineurally...
April 2016: Der Anaesthesist
https://www.readbyqxmd.com/read/26890790/local-drug-infiltration-analgesia-during-knee-surgery-to-reduce-postoperative-pain-in-rats
#13
Asokumar Buvanendran, Jeffrey S Kroin, Craig J Della Valle, Mario Moric, Kenneth J Tuman
BACKGROUND AND OBJECTIVES: There is increasing interest in local infiltration analgesia (LIA) to reduce postoperative pain with knee surgery. Despite widespread use of LIA, wide variations in drug combinations, infiltration techniques, and the concomitant use of systemic analgesics have made it difficult to determine the optimal drug combination for LIA.Using a previously validated animal knee surgery model, we aimed to determine the optimal combination of medications to reduce postoperative pain, and the best anatomical location and timing for local drug injection during surgery...
May 2016: Regional Anesthesia and Pain Medicine
https://www.readbyqxmd.com/read/26355598/local-anesthetic-peripheral-nerve-block-adjuvants-for-prolongation-of-analgesia-a-systematic-qualitative-review
#14
Meghan A Kirksey, Stephen C Haskins, Jennifer Cheng, Spencer S Liu
BACKGROUND: The use of peripheral nerve blocks for anesthesia and postoperative analgesia has increased significantly in recent years. Adjuvants are frequently added to local anesthetics to prolong analgesia following peripheral nerve blockade. Numerous randomized controlled trials and meta-analyses have examined the pros and cons of the use of various individual adjuvants. OBJECTIVES: To systematically review adjuvant-related randomized controlled trials and meta-analyses and provide clinical recommendations for the use of adjuvants in peripheral nerve blocks...
2015: PloS One
https://www.readbyqxmd.com/read/25886227/comparative-evaluation-of-ropivacaine-and-ropivacaine-with-dexamethasone-in-supraclavicular-brachial-plexus-block-for-postoperative-analgesia
#15
Santosh Kumar, Urmila Palaria, Ajay K Sinha, D C Punera, Vijita Pandey
BACKGROUND: Mixing of various adjuvants has been tried with local anesthetics in an attempt to prolong anesthesia from peripheral nerve blocks but have met with inconclusive success. More recent studies indicate that 8 mg dexamethasone added to perineural local anesthetic injections augment the duration of peripheral nerve block analgesia. AIMS: Evaluating the hypothesis that adding dexamethasone to ropivacaine significantly prolongs the duration of analgesia in supraclavicular brachial plexus block compared with ropivacaine alone...
May 2014: Anesthesia, Essays and Researches
https://www.readbyqxmd.com/read/25853044/pre-emptive-effect-of-dexamethasone-injection-and-consumption-on-post-operative-swelling-pain-and-trismus-after-third-molar-surgery-a-prospective-double-blind-and-randomized-study
#16
Pradeep D Chaudhary, Sanjay Rastogi, Prashant Gupta, B Niranjanaprasad Indra, Roy Thomas, Rupshikha Choudhury
AIM: To evaluate the preventative effect of intravenous 4 mg of dexamethasone and 8 mg oral dexamethasone on post-operative pain, swelling and trismus after the surgical extraction of mandibular third molars. MATERIALS AND METHODS: A randomized clinical trial comprised of 200 patients (control group I intravenous and experimental group II orally) with impacted lower third molars, average age 20.8 years with no local or systemic problems, with bilateral impacted lower third molars, were operated under local anesthesia...
January 2015: Journal of Oral Biology and Craniofacial Research
https://www.readbyqxmd.com/read/25785683/dexamethasone-added-to-local-lidocaine-for-infiltration-along-the-spinal-epidural-needle-pathway-decreases-incidence-and-severity-of-backache-after-gynecological-surgery
#17
RANDOMIZED CONTROLLED TRIAL
Wei Gao, Yi Ren, Guang Xiao Cui
BACKGROUND: The aim of this study was to evaluate the effect of dexamethasone added to local lidocaine infiltration on incidence and severity of backache after combined spinal-epidural anesthesia for gynecological surgery. MATERIAL AND METHODS: We randomly allocated 160 patients to receive either local lidocaine infiltration along the pathway of the spinal-epidural needle (Group L) or local dexamethasone and lidocaine infiltration (Group DL). The incidence and scores for back pain were evaluated on the first, second, and third day (acute lumbago) and first, second, and sixth month (chronic lumbago) after surgery...
2015: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/25675053/perineural-dexamethasone-added-to-local-anesthesia-for-brachial-plexus-block-improves-pain-but-delays-block-onset-and-motor-blockade-recovery
#18
REVIEW
Nebojsa Nick Knezevic, Utchariya Anantamongkol, Kenneth D Candido
BACKGROUND: Multiple studies have shown that perineural dexamethasone improves postoperative analgesia. However, some studies have shown minimal benefit, and have raised concerns regarding adverse physio-chemical effects of perineural dexamethasone. Furthermore, there is a paucity of studies wherein control (IV) dexamethasone was considered. OBJECTIVE: The purpose of this meta-analysis was to evaluate the effectiveness of different concentrations of perineural dexamethasone injection on postoperative analgesia, as well as complications from its use for brachial plexus blocks...
January 2015: Pain Physician
https://www.readbyqxmd.com/read/25637938/is-there-a-dose-response-of-dexamethasone-as-adjuvant-for-supraclavicular-brachial-plexus-nerve-block-a-prospective-randomized-double-blinded-clinical-study
#19
RANDOMIZED CONTROLLED TRIAL
Jiabin Liu, Kenneth A Richman, Samuel R Grodofsky, Siya Bhatt, George Russell Huffman, John D Kelly, David L Glaser, Nabil Elkassabany
STUDY OBJECTIVE: The study objective is to examine the analgesic effect of 3 doses of dexamethasone in combination with low concentration local anesthetics to determine the lowest effective dose of dexamethasone for use as an adjuvant in supraclavicular brachial plexus nerve block. DESIGN: The design is a prospective randomized double-blinded clinical study. SETTING: The setting is an academic medical center. PATIENTS: The patients are 89 adult patients scheduled for shoulder arthroscopy...
May 2015: Journal of Clinical Anesthesia
https://www.readbyqxmd.com/read/25376140/outcomes-of-arthrocentesis-for-the-treatment-of-internal-derangement-pain-with-or-without-corticosteroids
#20
RANDOMIZED CONTROLLED TRIAL
Reza Tabrizi, Tuba Karagah, Hamidreza Arabion, Mohammad Reza Soleimanpour, Mehrnaz Soleimanpour
PURPOSE: Arthrocentesis (AC) is an acceptable treatment modality in the treatment of internal derangement (ID) pain. This study evaluated outcomes of AC on pain relief of ID pain with or without corticosteroids. MATERIALS AND METHODS: This single-blind clinical trial was conducted on 60 patients with ID pain who were randomly assigned to 2 groups (30 in each group) for AC. The AC of the upper joint space was then performed by using Ringer lactate under local anesthesia in both groups...
November 2014: Journal of Craniofacial Surgery
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